Published in Pulm Med on March 21, 2011
MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation. Am J Respir Cell Mol Biol (2011) 1.12
Mechanistic links between aging and lung fibrosis. Biogerontology (2013) 0.91
Structure-function correlations of pulmonary surfactant protein SP-B and the saposin-like family of proteins. Eur Biophys J (2012) 0.89
Rapamycin increases CCN2 expression of lung fibroblasts via phosphoinositide 3-kinase. Lab Invest (2015) 0.81
p70 ribosomal S6 kinase regulates subpleural fibrosis following transforming growth factor-α expression in the lung. Am J Physiol Lung Cell Mol Physiol (2015) 0.80
Effects of rapamycin against paraquat-induced pulmonary fibrosis in mice. J Zhejiang Univ Sci B (2015) 0.79
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A mutation in the surfactant protein C gene associated with familial interstitial lung disease. N Engl J Med (2001) 4.68
Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred. Am J Respir Crit Care Med (2002) 4.66
Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis. Proc Natl Acad Sci U S A (2000) 3.47
Hydrophobic surfactant proteins in lung function and disease. N Engl J Med (2002) 2.94
mTOR, translational control and human disease. Semin Cell Dev Biol (2004) 2.77
Mortality from pulmonary fibrosis increased in the United States from 1992 to 2003. Am J Respir Crit Care Med (2007) 2.66
Rapamycin attenuates unilateral ureteral obstruction-induced renal fibrosis. Kidney Int (2006) 2.24
Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis. Int J Biochem Cell Biol (2009) 1.90
Rapamycin: something old, something new, sometimes borrowed and now renewed. Clin Pharmacol Ther (2007) 1.90
Mammalian target of rapamycin pathway blockade slows progression of diabetic kidney disease in rats. J Am Soc Nephrol (2006) 1.79
Genetic disorders of surfactant dysfunction. Pediatr Dev Pathol (2009) 1.77
Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin. Am J Pathol (2005) 1.76
Noninfectious pneumonitis after everolimus therapy for advanced renal cell carcinoma. Am J Respir Crit Care Med (2010) 1.66
Pneumonitis and emphysema in sp-C gene targeted mice. J Biol Chem (2003) 1.62
Conditional expression of transforming growth factor-alpha in adult mouse lung causes pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2003) 1.53
EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2008) 1.51
Mutation of SFTPC in infantile pulmonary alveolar proteinosis with or without fibrosing lung disease. Am J Med Genet A (2004) 1.39
Surfactant protein deficiency in familial interstitial lung disease. J Pediatr (2001) 1.37
Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis. Am J Respir Cell Mol Biol (2007) 1.29
Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis. J Hepatol (2006) 1.27
Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis. Am J Respir Cell Mol Biol (2009) 1.24
Brief communication: sirolimus-associated pneumonitis: 24 cases in renal transplant recipients. Ann Intern Med (2006) 1.20
The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats. Eur Respir J (2002) 1.13
Dysfunction of pulmonary surfactant in chronically ventilated premature infants. Pediatr Res (2004) 1.12
Low-dose mTOR inhibition by rapamycin attenuates progression in anti-thy1-induced chronic glomerulosclerosis of the rat. Am J Physiol Renal Physiol (2007) 1.10
A matrix for new ideas in pulmonary fibrosis. Am J Respir Cell Mol Biol (2002) 0.96
Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection. Am J Physiol Lung Cell Mol Physiol (2009) 0.96
Challenges in translating preclinical studies to effective drug therapies in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2010) 0.91
[Successful treatment of a severe case of idiopathic pulmonary fibrosis with rapamycin]. Med Klin (Munich) (2005) 0.88
Interstitial pneumonitis in the transplant patient: consider sirolimus-associated pulmonary toxicity. J La State Med Soc (2009) 0.86
Diffuse alveolar hemorrhage induced by everolimus. Chest (2010) 0.83
Maintenance of the mouse type II cell phenotype in vitro. Am J Physiol Lung Cell Mol Physiol (2002) 2.61
Foxa2 regulates alveolarization and goblet cell hyperplasia. Development (2004) 2.35
Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis. Am J Respir Cell Mol Biol (2014) 2.12
Emerging concepts in the pathogenesis of lung fibrosis. Am J Pathol (2009) 2.05
SP-B deficiency causes respiratory failure in adult mice. Am J Physiol Lung Cell Mol Physiol (2003) 2.00
Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin. Am J Pathol (2005) 1.76
Early gestational intra-amniotic endotoxin: lung function, surfactant, and morphometry. Am J Respir Crit Care Med (2002) 1.72
Gastrointestinal bleeding rates in recipients of nonpulsatile and pulsatile left ventricular assist devices. J Thorac Cardiovasc Surg (2008) 1.71
C/EBPalpha is required for lung maturation at birth. Development (2006) 1.65
Pneumonitis and emphysema in sp-C gene targeted mice. J Biol Chem (2003) 1.62
Differential effects of maternal betamethasone and cortisol on lung maturation and growth in fetal sheep. Am J Obstet Gynecol (2003) 1.60
The effects of intra-amniotic injection of periodontopathic lipopolysaccharides in sheep. Am J Obstet Gynecol (2005) 1.59
Foxa2 is required for transition to air breathing at birth. Proc Natl Acad Sci U S A (2004) 1.57
Stat-3 is required for pulmonary homeostasis during hyperoxia. J Clin Invest (2004) 1.51
EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2008) 1.51
Transcriptional programs controlling perinatal lung maturation. PLoS One (2012) 1.41
Decreased indicators of lung injury with continuous positive expiratory pressure in preterm lambs. Pediatr Res (2002) 1.38
Kruppel-like factor 5 is required for perinatal lung morphogenesis and function. Development (2008) 1.35
IL-1 mediates pulmonary and systemic inflammatory responses to chorioamnionitis induced by lipopolysaccharide. Am J Respir Crit Care Med (2009) 1.35
GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium. Am J Pathol (2008) 1.34
Calcineurin/Nfat signaling is required for perinatal lung maturation and function. J Clin Invest (2006) 1.33
Endotoxin-induced chorioamnionitis modulates innate immunity of monocytes in preterm sheep. Am J Respir Crit Care Med (2004) 1.31
Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis. Am J Respir Cell Mol Biol (2007) 1.29
LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice. J Clin Invest (2010) 1.27
Maternal glucocorticoids increase endotoxin-induced lung inflammation in preterm lambs. Am J Physiol Lung Cell Mol Physiol (2002) 1.25
Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis. Am J Respir Cell Mol Biol (2009) 1.24
Positive end-expiratory pressure and tidal volume during initial ventilation of preterm lambs. Pediatr Res (2008) 1.23
Vascular changes after intra-amniotic endotoxin in preterm lamb lungs. Am J Physiol Lung Cell Mol Physiol (2004) 1.22
GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression. J Biol Chem (2001) 1.19
Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production. Am J Respir Cell Mol Biol (2007) 1.19
Surfactant and physiologic responses of preterm lambs to continuous positive airway pressure. Am J Respir Crit Care Med (2004) 1.18
Experimental amniotic fluid infection in sheep: effects of Ureaplasma parvum serovars 3 and 6 on preterm or term fetal sheep. Am J Obstet Gynecol (2008) 1.17
Monocyte function in preterm, term, and adult sheep. Pediatr Res (2003) 1.17
Stat3 is required for cytoprotection of the respiratory epithelium during adenoviral infection. J Immunol (2006) 1.17
Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity. FASEB J (2006) 1.13
Complementation of pulmonary abnormalities in SP-D(-/-) mice with an SP-D/conglutinin fusion protein. J Biol Chem (2002) 1.12
Injury, inflammation, and remodeling in fetal sheep lung after intra-amniotic endotoxin. Am J Physiol Lung Cell Mol Physiol (2002) 1.12
MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation. Am J Respir Cell Mol Biol (2011) 1.12
Bubble continuous positive airway pressure enhances lung volume and gas exchange in preterm lambs. Am J Respir Crit Care Med (2007) 1.12
Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma. Am J Physiol Lung Cell Mol Physiol (2010) 1.12
Toll-like receptors and agonist responses in the developing fetal sheep lung. Pediatr Res (2008) 1.12
Patient-derived granulocyte/macrophage colony-stimulating factor autoantibodies reproduce pulmonary alveolar proteinosis in nonhuman primates. Am J Respir Crit Care Med (2010) 1.10
Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells. BMC Genomics (2007) 1.10
Intra-amniotic endotoxin induces lung maturation by direct effects on the developing respiratory tract in preterm sheep. Am J Obstet Gynecol (2002) 1.10
Deletion of Scap in alveolar type II cells influences lung lipid homeostasis and identifies a compensatory role for pulmonary lipofibroblasts. J Biol Chem (2008) 1.09
Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary fibrosis. Am J Pathol (2009) 1.07
Pulmonary and systemic induction of SAA3 after ventilation and endotoxin in preterm lambs. Pediatr Res (2005) 1.05
Surfactant protein B inhibits endotoxin-induced lung inflammation. Am J Respir Cell Mol Biol (2003) 1.05
Experimental intrauterine Ureaplasma infection in sheep. Am J Obstet Gynecol (2005) 1.05
Intra-amniotic injection of IL-1 induces inflammation and maturation in fetal sheep lung. Am J Physiol Lung Cell Mol Physiol (2002) 1.04
Antenatal betamethasone changes cord blood monocyte responses to endotoxin in preterm lambs. Pediatr Res (2004) 1.04
Intra-amniotic LPS and antenatal betamethasone: inflammation and maturation in preterm lamb lungs. Am J Physiol Lung Cell Mol Physiol (2011) 1.04
Chronic endotoxin exposure does not cause sustained structural abnormalities in the fetal sheep lungs. Am J Physiol Lung Cell Mol Physiol (2005) 1.03
Recruited inflammatory cells mediate endotoxin-induced lung maturation in preterm fetal lambs. Am J Respir Crit Care Med (2005) 1.03
Reversibility of pulmonary abnormalities by conditional replacement of surfactant protein D (SP-D) in vivo. J Biol Chem (2002) 1.01
Mapping and analysis of the lytic and fusogenic domains of surfactant protein B. Biochemistry (2005) 1.00
Early growth response-1 suppresses epidermal growth factor receptor-mediated airway hyperresponsiveness and lung remodeling in mice. Am J Respir Cell Mol Biol (2009) 1.00
Partial SP-B deficiency perturbs lung function and causes air space abnormalities. Am J Physiol Lung Cell Mol Physiol (2005) 1.00
Acute lung injury: functional genomics and genetic susceptibility. Chest (2002) 1.00
Inhibitors of inflammation and endogenous surfactant pool size as modulators of lung injury with initiation of ventilation in preterm sheep. Respir Res (2010) 0.99
Ibuprofen-induced patent ductus arteriosus closure: physiologic, histologic, and biochemical effects on the premature lung. Pediatrics (2008) 0.99
Correction of pulmonary abnormalities in Sftpd-/- mice requires the collagenous domain of surfactant protein D. J Biol Chem (2006) 0.98
C/EBP{alpha} is required for pulmonary cytoprotection during hyperoxia. Am J Physiol Lung Cell Mol Physiol (2009) 0.97
IL-1 alpha causes lung inflammation and maturation by direct effects on preterm fetal lamb lungs. Pediatr Res (2006) 0.97
Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection. Am J Physiol Lung Cell Mol Physiol (2009) 0.96
Macrophage dysfunction and susceptibility to pulmonary Pseudomonas aeruginosa infection in surfactant protein C-deficient mice. J Immunol (2008) 0.96
Acceptability and repeatability of spirometry in children using updated ATS/ERS criteria. Pediatr Pulmonol (2008) 0.96
Betamethasone effects on chorioamnionitis induced by intra-amniotic endotoxin in sheep. Am J Obstet Gynecol (2003) 0.96
An MRI system for imaging neonates in the NICU: initial feasibility study. Pediatr Radiol (2012) 0.96
Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice. Am J Physiol Lung Cell Mol Physiol (2010) 0.95
The genetics of ray pattern variation in Caenorhabditis briggsae. BMC Evol Biol (2005) 0.94
Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size. Am J Respir Cell Mol Biol (2013) 0.94
SP-B and SP-C containing new synthetic surfactant for treatment of extremely immature lamb lung. PLoS One (2012) 0.94
IL-8 signaling does not mediate intra-amniotic LPS-induced inflammation and maturation in preterm fetal lamb lung. Am J Physiol Lung Cell Mol Physiol (2009) 0.94
Intratracheal endotoxin causes systemic inflammation in ventilated preterm lambs. Am J Respir Crit Care Med (2002) 0.94
Perinatal increases in TGF-{alpha} disrupt the saccular phase of lung morphogenesis and cause remodeling: microarray analysis. Am J Physiol Lung Cell Mol Physiol (2007) 0.94
NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. J Immunol (2012) 0.94
Surfactant protein-d inhibits lung inflammation caused by ventilation in premature newborn lambs. Am J Respir Crit Care Med (2010) 0.93
Persistence of LPS-induced lung inflammation in surfactant protein-C-deficient mice. Am J Respir Cell Mol Biol (2013) 0.93
Increased IP-10 and MIG expression after intra-amniotic endotoxin in preterm lamb lung. Am J Respir Crit Care Med (2003) 0.93
Pathogenesis of Interstitial Lung Disease in Children and Adults. Pediatr Allergy Immunol Pulmonol (2010) 0.93
Deficiency of SP-B reveals protective role of SP-C during oxygen lung injury. J Appl Physiol (1985) (2002) 0.92
Conditional hypoxia inducible factor-1α induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis. Dev Biol (2011) 0.92
Disrupted pulmonary vascular development and pulmonary hypertension in transgenic mice overexpressing transforming growth factor-alpha. Am J Physiol Lung Cell Mol Physiol (2003) 0.91
Leptin does not influence surfactant synthesis in fetal sheep and mice lungs. Am J Physiol Lung Cell Mol Physiol (2011) 0.91
Resistin-like molecule α1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis. Respir Res (2012) 0.91
Surface tension influences cell shape and phagocytosis in alveolar macrophages. Am J Physiol Lung Cell Mol Physiol (2006) 0.90
Ureaplasma colonization of amniotic fluid and efficacy of antenatal corticosteroids for preterm lung maturation in sheep. Am J Obstet Gynecol (2009) 0.90
Betamethasone for lung maturation: testing dose and formulation in fetal sheep. Am J Obstet Gynecol (2007) 0.90
In vivo measurements of changes in respiratory mechanics with age in mice deficient in surfactant protein D. Pediatr Res (2003) 0.90
The murine SP-C promoter directs type II cell-specific expression in transgenic mice. Am J Physiol Lung Cell Mol Physiol (2004) 0.90
The fetal maturational and inflammatory responses to different routes of endotoxin infusion in sheep. Am J Obstet Gynecol (2002) 0.90