White matter damage in primary progressive aphasias: a diffusion tensor tractography study.

PubWeight™: 1.73‹?› | Rank: Top 3%

🔗 View Article (PMC 3187537)

Published in Brain on June 11, 2011

Authors

Sebastiano Galantucci1, Maria Carmela Tartaglia, Stephen M Wilson, Maya L Henry, Massimo Filippi, Federica Agosta, Nina F Dronkers, Roland G Henry, Jennifer M Ogar, Bruce L Miller, Maria Luisa Gorno-Tempini

Author Affiliations

1: Memory and Ageing Centre, Department of Neurology, University of California, San Francisco, San Francisco, CA 94143-1207, USA.

Associated clinical trials:

Language Functional Reorganization in Subcortical Infarction Patients | NCT03668132

Articles citing this

Dissecting the uncinate fasciculus: disorders, controversies and a hypothesis. Brain (2013) 1.59

The non-fluent/agrammatic variant of primary progressive aphasia. Lancet Neurol (2012) 1.33

A novel frontal pathway underlies verbal fluency in primary progressive aphasia. Brain (2013) 1.32

Syntactic processing depends on dorsal language tracts. Neuron (2011) 1.31

Frontotemporal dementia: implications for understanding Alzheimer disease. Cold Spring Harb Perspect Med (2012) 1.23

The paradox of syndromic diversity in Alzheimer disease. Nat Rev Neurol (2012) 1.18

Dynamic processing in the human language system: synergy between the arcuate fascicle and extreme capsule. J Neurosci (2011) 1.13

White matter imaging contributes to the multimodal diagnosis of frontotemporal lobar degeneration. Neurology (2012) 1.05

Disruption of large-scale neural networks in non-fluent/agrammatic variant primary progressive aphasia associated with frontotemporal degeneration pathology. Brain Lang (2012) 1.01

Tracing superior longitudinal fasciculus connectivity in the human brain using high resolution diffusion tensor tractography. Brain Struct Funct (2013) 0.97

White matter tract signatures of the progressive aphasias. Neurobiol Aging (2013) 0.95

White matter atrophy in Alzheimer's disease variants. Alzheimers Dement (2012) 0.91

Frontal white matter tracts sustaining speech production in primary progressive aphasia. J Neurosci (2014) 0.90

The neural basis of syntactic deficits in primary progressive aphasia. Brain Lang (2012) 0.90

MRI signatures of brain macrostructural atrophy and microstructural degradation in frontotemporal lobar degeneration subtypes. J Alzheimers Dis (2013) 0.89

White matter abnormalities correlating with memory and depression in heroin users under methadone maintenance treatment. PLoS One (2012) 0.86

Mapping a lateralization gradient within the ventral stream for auditory speech perception. Front Hum Neurosci (2013) 0.85

In vivo signatures of nonfluent/agrammatic primary progressive aphasia caused by FTLD pathology. Neurology (2013) 0.85

Clinical, cognitive, and behavioural correlates of white matter damage in progressive supranuclear palsy. J Neurol (2014) 0.84

Grammatical comprehension deficits in non-fluent/agrammatic primary progressive aphasia. J Neurol Neurosurg Psychiatry (2013) 0.83

Ideomotor apraxia in agrammatic and logopenic variants of primary progressive aphasia. J Neurol (2013) 0.82

Clinical and neuroimaging biomarkers of amyloid-negative logopenic primary progressive aphasia. Brain Lang (2015) 0.81

Grammatical Impairments in PPA. Aphasiology (2014) 0.81

Pediatric traumatic brain injury: language outcomes and their relationship to the arcuate fasciculus. Brain Lang (2013) 0.81

Motor Speech Disorders Associated with Primary Progressive Aphasia. Aphasiology (2014) 0.81

Local but not long-range microstructural differences of the ventral temporal cortex in developmental prosopagnosia. Neuropsychologia (2015) 0.80

A multimodal neuroimaging study of a case of crossed nonfluent/agrammatic primary progressive aphasia. J Neurol (2015) 0.80

Upper motor neuron involvement in amyotrophic lateral sclerosis evaluated by triple stimulation technique and diffusion tensor MRI. J Neurol (2013) 0.80

Identification of an atypical variant of logopenic progressive aphasia. Brain Lang (2013) 0.80

Contributions of bilateral white matter to chronic aphasia symptoms as assessed by diffusion tensor MRI. Brain Lang (2015) 0.79

White matter disease correlates with lexical retrieval deficits in primary progressive aphasia. Front Neurol (2013) 0.78

Recent advances in the imaging of frontotemporal dementia. Curr Neurol Neurosci Rep (2012) 0.78

The semantic variant of primary progressive aphasia: clinical and neuroimaging evidence in single subjects. PLoS One (2015) 0.78

White matter abnormalities and impaired attention abilities in children born very preterm. Neuroimage (2015) 0.78

Longitudinal gray matter contraction in three variants of primary progressive aphasia: A tenser-based morphometry study. Neuroimage Clin (2015) 0.78

White matter tract signatures of impaired social cognition in frontotemporal lobar degeneration. Neuroimage Clin (2015) 0.77

Healthy brain connectivity predicts atrophy progression in non-fluent variant of primary progressive aphasia. Brain (2016) 0.77

Segregation of anterior temporal regions critical for retrieving names of unique and non-unique entities reflects underlying long-range connectivity. Cortex (2015) 0.77

Classification of the primary progressive aphasias: principles and review of progress since 2011. Alzheimers Res Ther (2016) 0.76

Dissociation of quantifiers and object nouns in speech in focal neurodegenerative disease. Neuropsychologia (2016) 0.76

Neuropsychological, behavioral, and anatomical evolution in right temporal variant frontotemporal dementia: a longitudinal and post-mortem single case analysis. Neurocase (2012) 0.76

Structural connectivity of the human anterior temporal lobe: A diffusion magnetic resonance imaging study. Hum Brain Mapp (2016) 0.76

A clinicopathological approach to the diagnosis of dementia. Nat Rev Neurol (2017) 0.75

Frontotemporal networks and behavioral symptoms in primary progressive aphasia. Neurology (2016) 0.75

Diverging Progression of Network Disruption and Atrophy in Alzheimer's Disease and Semantic Dementia. J Alzheimers Dis (2016) 0.75

Critical Neural Networks in Awake Surgery for Gliomas. Neurol Med Chir (Tokyo) (2016) 0.75

The Brain Network of Naming: A Lesson from Primary Progressive Aphasia. PLoS One (2016) 0.75

Early-Onset Alzheimer Disease. Neurol Clin (2017) 0.75

Hemispheric Differences in White Matter Microstructure between Two Profiles of Children with High Intelligence Quotient vs. Controls: A Tract-Based Spatial Statistics Study. Front Neurosci (2017) 0.75

Biomarkers in the primary progressive aphasias. Aphasiology (2014) 0.75

Setting new tracks: not just creating another pretty picture. Brain (2011) 0.75

The Dorsal Rather than Ventral Pathway Better Reflects Individual Syntactic Abilities in Second Language. Front Hum Neurosci (2016) 0.75

Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease. Neuroimage Clin (2017) 0.75

Advanced magnetic resonance imaging of neurodegenerative diseases. Neurol Sci (2016) 0.75

The common dementias: a pictorial review. Eur Radiol (2013) 0.75

White Matter Disruption and Connected Speech in Non-Fluent and Semantic Variants of Primary Progressive Aphasia. Dement Geriatr Cogn Dis Extra (2017) 0.75

Articles cited by this

Unified segmentation. Neuroimage (2005) 30.20

Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology (1998) 26.77

MR diffusion tensor spectroscopy and imaging. Biophys J (1994) 22.78

A fast diffeomorphic image registration algorithm. Neuroimage (2007) 21.56

The basis of anisotropic water diffusion in the nervous system - a technical review. NMR Biomed (2002) 16.60

Probabilistic diffusion tractography with multiple fibre orientations: What can we gain? Neuroimage (2006) 12.78

Characterization and propagation of uncertainty in diffusion-weighted MR imaging. Magn Reson Med (2003) 12.09

Classification of primary progressive aphasia and its variants. Neurology (2011) 11.82

Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage (2002) 11.37

Cognition and anatomy in three variants of primary progressive aphasia. Ann Neurol (2004) 7.07

Virtual in vivo interactive dissection of white matter fasciculi in the human brain. Neuroimage (2002) 6.99

Perisylvian language networks of the human brain. Ann Neurol (2005) 6.66

Slowly progressive aphasia without generalized dementia. Ann Neurol (1982) 5.66

Segmentation of subcomponents within the superior longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI study. Cereb Cortex (2004) 4.50

Diffusion tensor imaging (DTI)-based white matter mapping in brain research: a review. J Mol Neurosci (2008) 4.48

Clinical and pathological characterization of progressive aphasia. Ann Neurol (2006) 4.37

Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies. Am J Pathol (2006) 4.32

A diffusion tensor imaging tractography atlas for virtual in vivo dissections. Cortex (2008) 4.26

A voxel-based morphometry study of semantic dementia: relationship between temporal lobe atrophy and semantic memory. Ann Neurol (2000) 4.22

Abeta amyloid and glucose metabolism in three variants of primary progressive aphasia. Ann Neurol (2008) 4.15

About "axial" and "radial" diffusivities. Magn Reson Med (2009) 4.13

Clinicopathological and imaging correlates of progressive aphasia and apraxia of speech. Brain (2006) 4.07

Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia. Ann Neurol (2008) 3.99

The logopenic/phonological variant of primary progressive aphasia. Neurology (2008) 3.95

Primary progressive aphasia. Ann Neurol (2001) 3.72

The evolution of the arcuate fasciculus revealed with comparative DTI. Nat Neurosci (2008) 3.65

The evolution and pathology of frontotemporal dementia. Brain (2005) 3.46

Understanding diffusion MR imaging techniques: from scalar diffusion-weighted imaging to diffusion tensor imaging and beyond. Radiographics (2006) 3.37

Office of Rare Diseases neuropathologic criteria for corticobasal degeneration. J Neuropathol Exp Neurol (2002) 3.02

The pathological basis of semantic dementia. Brain (2005) 2.96

DTI tractography of the human brain's language pathways. Cereb Cortex (2008) 2.84

Quantitative investigation of connections of the prefrontal cortex in the human and macaque using probabilistic diffusion tractography. J Neurosci (2005) 2.72

11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration. Neurology (2007) 2.65

The brain differentiates human and non-human grammars: functional localization and structural connectivity. Proc Natl Acad Sci U S A (2006) 2.60

Dissociating the human language pathways with high angular resolution diffusion fiber tractography. J Neurosci (2008) 2.50

Morphometry of in vivo human white matter association pathways with diffusion-weighted magnetic resonance imaging. Ann Neurol (1997) 2.48

Clinical syndromes associated with posterior atrophy: early age at onset AD spectrum. Neurology (2009) 2.46

Progressive aphasia secondary to Alzheimer disease vs FTLD pathology. Neurology (2008) 2.45

Quantitative template for subtyping primary progressive aphasia. Arch Neurol (2009) 2.42

Frontotemporal lobar degeneration: clinical and pathological relationships. Acta Neuropathol (2007) 2.33

The natural history of temporal variant frontotemporal dementia. Neurology (2005) 2.22

Primary progressive aphasia: clinicopathological correlations. Nat Rev Neurol (2010) 2.19

Alzheimer's disease: areal and laminar pathology in the occipital isocortex. Acta Neuropathol (1989) 2.09

White matter damage in frontotemporal dementia and Alzheimer's disease measured by diffusion MRI. Brain (2009) 2.08

Absolute diffusivities define the landscape of white matter degeneration in Alzheimer's disease. Brain (2009) 2.08

MR tractography: a review of its clinical applications. Magn Reson Med Sci (2009) 2.07

Nonfluent progressive aphasia and semantic dementia: a comparative neuropsychological study. J Int Neuropsychol Soc (1996) 2.04

TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions. J Neuropathol Exp Neurol (2007) 2.02

Regionally-specific diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease. Neuroimage (2009) 1.92

Diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease: a review. Curr Opin Neurol (2008) 1.92

Behavioral features in semantic dementia vs other forms of progressive aphasias. Neurology (2006) 1.80

Atrophy progression in semantic dementia with asymmetric temporal involvement: a tensor-based morphometry study. Neurobiol Aging (2007) 1.74

Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management. CNS Drugs (2010) 1.72

Dementia lacking distinctive histology (DLDH) revisited. Acta Neuropathol (2006) 1.58

White matter tract integrity in aging and Alzheimer's disease. Hum Brain Mapp (2009) 1.57

Gray and white matter water diffusion in the syndromic variants of frontotemporal dementia. Neurology (2010) 1.57

Automated MRI-based classification of primary progressive aphasia variants. Neuroimage (2009) 1.55

Language networks in semantic dementia. Brain (2009) 1.50

Longitudinal decline in autopsy-defined frontotemporal lobar degeneration. Neurology (2008) 1.48

Evidence of white matter changes on diffusion tensor imaging in frontotemporal dementia. Arch Neurol (2007) 1.42

Neuropathology of white matter changes in Alzheimer's disease and vascular dementia. Dement Geriatr Cogn Disord (1998) 1.41

Delineation of the middle longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI study. Cereb Cortex (2008) 1.30

Sporadic Pick's disease: a tauopathy characterized by a spectrum of pathological tau isoforms in gray and white matter. Ann Neurol (2002) 1.30

Multimodal predictors for Alzheimer disease in nonfluent primary progressive aphasia. Neurology (2010) 1.24

White matter diffusion alterations in normal women at risk of Alzheimer's disease. Neurobiol Aging (2008) 1.22

What is the role of the uncinate fasciculus? Surgical removal and proper name retrieval. Brain (2010) 1.22

Cerebral white matter damage in frontotemporal dementia assessed by diffusion tensor tractography. Neuroradiology (2008) 1.22

The logopenic variant of primary progressive aphasia. Curr Opin Neurol (2010) 1.06

Unexpected abundance of pathological tau in progressive supranuclear palsy white matter. Ann Neurol (2006) 0.98

Clinicopathological characterization of Pick's disease versus frontotemporal lobar degeneration with ubiquitin/TDP-43-positive inclusions. Acta Neuropathol (2009) 0.91

Social and emotional functioning following bilateral and unilateral neurosurgical prefrontal cortex lesions. J Neuropsychol (2009) 0.84

Articles by these authors

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science (2006) 27.96

Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol (2011) 25.66

Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol (2005) 24.22

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron (2011) 20.15

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain (2011) 9.90

Neurodegenerative diseases target large-scale human brain networks. Neuron (2009) 9.69

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature (2005) 8.55

Cognition and anatomy in three variants of primary progressive aphasia. Ann Neurol (2004) 7.07

Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med (2007) 6.80

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52

Frontotemporal dementia: clinicopathological correlations. Ann Neurol (2006) 5.14

Voxel-based lesion-symptom mapping. Nat Neurosci (2003) 5.07

Abeta amyloid and glucose metabolism in three variants of primary progressive aphasia. Ann Neurol (2008) 4.15

Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease. Brain (2010) 3.84

Clinical, neuroimaging and neuropathological features of a new chromosome 9p-linked FTD-ALS family. J Neurol Neurosurg Psychiatry (2010) 3.66

Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease. Cogn Behav Neurol (2003) 3.66

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol (2011) 3.52

MRI criteria for multiple sclerosis in patients presenting with clinically isolated syndromes: a multicentre retrospective study. Lancet Neurol (2007) 3.47

250 microg or 500 microg interferon beta-1b versus 20 mg glatiramer acetate in relapsing-remitting multiple sclerosis: a prospective, randomised, multicentre study. Lancet Neurol (2009) 3.37

Challenging the clinical utility of the 14-3-3 protein for the diagnosis of sporadic Creutzfeldt-Jakob disease. Arch Neurol (2003) 3.20

Placebo-controlled trial of oral laquinimod for multiple sclerosis. N Engl J Med (2012) 3.16

Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: initial experience. Radiology (2005) 3.14

Diffusion-weighted and fluid-attenuated inversion recovery imaging in Creutzfeldt-Jakob disease: high sensitivity and specificity for diagnosis. AJNR Am J Neuroradiol (2005) 3.11

Predicting regional neurodegeneration from the healthy brain functional connectome. Neuron (2012) 3.07

Criteria for the diagnosis of corticobasal degeneration. Neurology (2013) 3.07

Frontal paralimbic network atrophy in very mild behavioral variant frontotemporal dementia. Arch Neurol (2008) 3.03

Rapidly progressive dementia. Ann Neurol (2008) 3.00

Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies. J Neuropathol Exp Neurol (2008) 2.96

Neuroanatomical correlates of behavioural disorders in dementia. Brain (2005) 2.92

Unravelling Boléro: progressive aphasia, transmodal creativity and the right posterior neocortex. Brain (2007) 2.75

Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia. Brain (2007) 2.72

Clinical and pathological continuum of multisystem TDP-43 proteinopathies. Arch Neurol (2009) 2.68

Chronic cerebrospinal venous insufficiency and multiple sclerosis. Ann Neurol (2010) 2.63

Diffusion tensor imaging: serial quantitation of white matter tract maturity in premature newborns. Neuroimage (2004) 2.58

The essential role of premotor cortex in speech perception. Curr Biol (2007) 2.58

The neural architecture of the language comprehension network: converging evidence from lesion and connectivity analyses. Front Syst Neurosci (2011) 2.56

Congruent embodied representations for visually presented actions and linguistic phrases describing actions. Curr Biol (2006) 2.45

Evidence for acute neurotoxicity after chemotherapy. Ann Neurol (2010) 2.45

MRI and the diagnosis of multiple sclerosis: expanding the concept of "no better explanation". Lancet Neurol (2006) 2.44

Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Am J Pathol (2008) 2.41

Early frontotemporal dementia targets neurons unique to apes and humans. Ann Neurol (2006) 2.38

Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Arch Neurol (2005) 2.36

FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration. Acta Neuropathol (2010) 2.30

Structural anatomy of empathy in neurodegenerative disease. Brain (2006) 2.28

Patterns of brain atrophy that differentiate corticobasal degeneration syndrome from progressive supranuclear palsy. Arch Neurol (2006) 2.27

Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons. Acta Neuropathol (2013) 2.26

Heritability of lobar brain volumes in twins supports genetic models of cerebral laterality and handedness. Proc Natl Acad Sci U S A (2002) 2.24

Cortical lesions and atrophy associated with cognitive impairment in relapsing-remitting multiple sclerosis. Arch Neurol (2009) 2.20

Connected speech production in three variants of primary progressive aphasia. Brain (2010) 2.19

The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration. Arch Neurol (2010) 2.19

A randomised, double blind, placebo controlled trial with vitamin D3 as an add on treatment to interferon β-1b in patients with multiple sclerosis. J Neurol Neurosurg Psychiatry (2012) 2.13

Quantitative diffusion tensor MRI fiber tractography of sensorimotor white matter development in premature infants. Neuroimage (2005) 2.13

Diagnosis of human prion disease. Proc Natl Acad Sci U S A (2005) 2.13

Sporadic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease. Arch Neurol (2003) 2.12

Clinically isolated syndromes suggestive of multiple sclerosis, part I: natural history, pathogenesis, diagnosis, and prognosis. Lancet Neurol (2005) 2.10

Spatiotemporal dynamics of word processing in the human brain. Front Neurosci (2007) 2.09

White matter damage in frontotemporal dementia and Alzheimer's disease measured by diffusion MRI. Brain (2009) 2.08

MRI in multiple sclerosis: current status and future prospects. Lancet Neurol (2008) 2.08

Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08

Magnetic resonance imaging pattern in natalizumab-associated progressive multifocal leukoencephalopathy. Ann Neurol (2012) 2.05

TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions. J Neuropathol Exp Neurol (2007) 2.02

Cortical adaptation in patients with MS: a cross-sectional functional MRI study of disease phenotypes. Lancet Neurol (2005) 2.01

Functional connectivity tracks clinical deterioration in Alzheimer's disease. Neurobiol Aging (2011) 2.01

Large-scale neuronal network dysfunction in relapsing-remitting multiple sclerosis. Neurology (2012) 2.00

Cognitive processing speed and the structure of white matter pathways: convergent evidence from normal variation and lesion studies. Neuroimage (2008) 1.99

Case records of the Massachusetts General Hospital. Case 9-2015. A 31-year-old man with personality changes and progressive neurologic decline. N Engl J Med (2015) 1.97

Neural stem cell engraftment and myelination in the human brain. Sci Transl Med (2012) 1.96

Serial quantitative diffusion tensor MRI of the premature brain: development in newborns with and without injury. J Magn Reson Imaging (2002) 1.96

Neuroimaging studies of word and pseudoword reading: consistencies, inconsistencies, and limitations. J Cogn Neurosci (2003) 1.92

Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease. Brain (2013) 1.91

TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia. Acta Neuropathol (2014) 1.90

Longitudinal MRI and cognitive change in healthy elderly. Neuropsychology (2007) 1.88

Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia. J Biol Chem (2011) 1.88

Relationships between β-amyloid and functional connectivity in different components of the default mode network in aging. Cereb Cortex (2011) 1.87

Clinicopathological correlations in corticobasal degeneration. Ann Neurol (2011) 1.86

Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden. Brain (2010) 1.86

Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol (2013) 1.84

Age effects on atrophy rates of entorhinal cortex and hippocampus. Neurobiol Aging (2005) 1.83

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease. Mol Neurodegener (2013) 1.83