Published in Hepatology on August 08, 2011
An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell (2011) 4.29
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms. Nat Rev Cancer (2013) 4.02
Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model. J Exp Med (2013) 2.50
Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma. Gastroenterology (2013) 2.21
Hepatoprotective and anti-inflammatory cytokines in alcoholic liver disease. J Gastroenterol Hepatol (2012) 1.49
Immunity, inflammation, and cancer: an eternal fight between good and evil. J Clin Invest (2015) 1.24
Pivotal roles of T-helper 17-related cytokines, IL-17, IL-22, and IL-23, in inflammatory diseases. Clin Dev Immunol (2013) 1.20
Therapy for alcoholic liver disease. World J Gastroenterol (2014) 1.17
STAT proteins - key regulators of anti-viral responses, inflammation, and tumorigenesis in the liver. J Hepatol (2012) 1.15
Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences. Cell Biosci (2015) 1.15
Interleukin-22 serum levels are a negative prognostic indicator in patients with hepatocellular carcinoma. Hepatology (2013) 1.12
Increased circulating Th22 and Th17 cells are associated with tumor progression and patient survival in human gastric cancer. J Clin Immunol (2012) 1.07
Recent advancement of molecular mechanisms of liver fibrosis. J Hepatobiliary Pancreat Sci (2015) 1.05
Cytokines and STATs in Liver Fibrosis. Front Physiol (2012) 1.02
Interleukin-22 ameliorates cerulein-induced pancreatitis in mice by inhibiting the autophagic pathway. Int J Biol Sci (2012) 1.02
IL-22 is related to development of human colon cancer by activation of STAT3. BMC Cancer (2013) 1.01
Expanding roles for CD4 T cells and their subpopulations in tumor immunity and therapy. Front Oncol (2013) 0.99
IL-22 in tissue-protective therapy. Br J Pharmacol (2013) 0.98
Inflammatory immune responses in tumor microenvironment and metastasis of hepatocellular carcinoma. Cancer Microenviron (2012) 0.94
Hepatoprotective and anti-fibrotic functions of interleukin-22: therapeutic potential for the treatment of alcoholic liver disease. J Gastroenterol Hepatol (2013) 0.94
Interleukin-37 mediates the antitumor activity in hepatocellular carcinoma: role for CD57+ NK cells. Sci Rep (2014) 0.93
Pro-tumour activity of interleukin-22 in HPAFII human pancreatic cancer cells. Clin Exp Immunol (2012) 0.92
Th22 cells are associated with hepatocellular carcinoma development and progression. Chin J Cancer Res (2014) 0.92
B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets. J Clin Invest (2014) 0.89
Diagnosis and Management of Alcoholic Liver Disease. J Clin Transl Hepatol (2015) 0.89
IL-22 produced by cancer-associated fibroblasts promotes gastric cancer cell invasion via STAT3 and ERK signaling. Br J Cancer (2014) 0.87
Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival. Oncoimmunology (2015) 0.87
Hepatitis C virus activates Bcl-2 and MMP-2 expression through multiple cellular signaling pathways. J Virol (2012) 0.85
Effects of antiviral therapy on preventing liver tumorigenesis and hepatocellular carcinoma recurrence. World J Gastroenterol (2013) 0.85
Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study. BMC Med (2012) 0.85
The multifaceted role of Th17 lymphocytes and their associated cytokines in cancer. Clin Dev Immunol (2013) 0.85
Increased Tc22 and Treg/CD8 ratio contribute to aggressive growth of transplant associated squamous cell carcinoma. PLoS One (2013) 0.85
Interleukins in chronic liver disease: lessons learned from experimental mouse models. Clin Exp Gastroenterol (2014) 0.85
Expression of interleukin-22/STAT3 signaling pathway in ulcerative colitis and related carcinogenesis. World J Gastroenterol (2013) 0.85
Role of interleukin-22 in liver diseases. Inflamm Res (2014) 0.81
miR-19b downregulates intestinal SOCS3 to reduce intestinal inflammation in Crohn's disease. Sci Rep (2015) 0.81
Biological and pathological activities of interleukin-22. J Mol Med (Berl) (2016) 0.80
T Helper Lymphocyte Subsets and Plasticity in Autoimmunity and Cancer: An Overview. Biomed Res Int (2015) 0.80
Interleukin (IL)-22 receptor 1 is over-expressed in primary Sjogren's syndrome and Sjögren-associated non-Hodgkin lymphomas and is regulated by IL-18. Clin Exp Immunol (2015) 0.79
IL22/IL-22R pathway induces cell survival in human glioblastoma cells. PLoS One (2015) 0.79
Regulation of T helper 17 by bacteria: an approach for the treatment of hepatocellular carcinoma. Int J Hepatol (2012) 0.78
IL-22 promotes the migration and invasion of gastric cancer cells via IL-22R1/AKT/MMP-9 signaling. Int J Clin Exp Pathol (2014) 0.78
The interplay between the microbiome and the adaptive immune response in cancer development. Therap Adv Gastroenterol (2016) 0.78
Highest frequencies of interleukin-22-producing T helper cells in alcoholic hepatitis patients with a favourable short-term course. PLoS One (2013) 0.77
Emerging Role of Interleukin 22 in Hepatitis B Virus Infection: a Double-edged Sword. J Clin Transl Hepatol (2013) 0.77
Mouse models of liver cancer: Progress and recommendations. Oncotarget (2015) 0.77
The crystal structure of zebrafish IL-22 reveals an evolutionary, conserved structure highly similar to that of human IL-22. Genes Immun (2014) 0.76
The Role of IL-22 in Viral Infections: Paradigms and Paradoxes. Front Immunol (2016) 0.76
New Approaches for Studying Alcoholic Liver Disease. Curr Pathobiol Rep (2014) 0.76
Matrix stiffness-mediated effects on stemness characteristics occurring in HCC cells. Oncotarget (2016) 0.76
The inflammatory cytokine IL-22 promotes murine gliomas via proliferation. Exp Ther Med (2017) 0.75
Th-17 regulatory cytokines inhibit corticosteroid induced airway structural cells apoptosis. Respir Res (2016) 0.75
SOCS3 genetic variants and promoter hypermethylation in patients with chronic hepatitis B. Oncotarget (2017) 0.75
STAT3, a Key Parameter of Cytokine-Driven Tissue Protection during Sterile Inflammation - the Case of Experimental Acetaminophen (Paracetamol)-Induced Liver Damage. Front Immunol (2016) 0.75
How Does Interleukin-22 Mediate Liver Regeneration and Prevent Injury and Fibrosis? J Immunol Res (2016) 0.75
Pathological Roles of Interleukin-22 in the Development of Recurrent Hepatitis C after Liver Transplantation. PLoS One (2016) 0.75
Th22 cells control colon tumorigenesis through STAT3 and Polycomb Repression complex 2 signaling. Oncoimmunology (2015) 0.75
Reply: To PMID 21674558. Hepatology (2014) 0.75
The role of IL-17 signaling in regulation of the liver-brain axis and intestinal permeability in Alcoholic Liver Disease. Curr Pathobiol Rep (2016) 0.75
The long noncoding RNA lnc-EGFR stimulates T-regulatory cells differentiation thus promoting hepatocellular carcinoma immune evasion. Nat Commun (2017) 0.75
Expression of IL-23/Th17-related cytokines in basal cell carcinoma and in the response to medical treatments. PLoS One (2017) 0.75
The roles of signal transducer and activator of transcription factor 3 in tumor angiogenesis. Oncotarget (2017) 0.75
A promoter-level mammalian expression atlas. Nature (2014) 6.25
Bayesian population decoding of motor cortical activity using a Kalman filter. Neural Comput (2006) 3.63
Phosphotyrosine interactome of the ErbB-receptor kinase family. Mol Syst Biol (2005) 3.48
Structure-based prediction of protein-protein interactions on a genome-wide scale. Nature (2012) 3.37
Efficacy and safety of three antiretroviral regimens for initial treatment of HIV-1: a randomized clinical trial in diverse multinational settings. PLoS Med (2012) 2.40
Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells. J Immunol (2010) 2.20
Simultaneous stretching and contraction of stress fibers in vivo. Mol Biol Cell (2004) 2.12
Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality. Nat Struct Mol Biol (2013) 2.11
Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells. Autophagy (2009) 2.09
Calcineurin/NFAT signaling in osteoblasts regulates bone mass. Dev Cell (2006) 1.95
The genomics of selection in dogs and the parallel evolution between dogs and humans. Nat Commun (2013) 1.86
Bax regulates primary necrosis through mitochondrial dynamics. Proc Natl Acad Sci U S A (2012) 1.80
The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4. J Mol Biol (2012) 1.69
Comparison of craniotomy and decompressive craniectomy in severely head-injured patients with acute subdural hematoma. J Trauma (2011) 1.60
PrePPI: a structure-informed database of protein-protein interactions. Nucleic Acids Res (2012) 1.59
Modeling and decoding motor cortical activity using a switching Kalman filter. IEEE Trans Biomed Eng (2004) 1.53
Cross species comparison of C/EBPα and PPARγ profiles in mouse and human adipocytes reveals interdependent retention of binding sites. BMC Genomics (2011) 1.52
Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genes. Nat Struct Mol Biol (2011) 1.51
Lack of synergy for inhibitors targeting a multi-drug-resistant HIV-1 protease. Protein Sci (2002) 1.49
Developed and developing world responsibilities for historical climate change and CO2 mitigation. Proc Natl Acad Sci U S A (2012) 1.44
Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90. J Med Chem (2006) 1.42
Mitochondrial fusion directs cardiomyocyte differentiation via calcineurin and Notch signaling. Science (2013) 1.39
Ultralow nanoscale wear through atom-by-atom attrition in silicon-containing diamond-like carbon. Nat Nanotechnol (2010) 1.34
Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer. Clin Proteomics (2011) 1.32
Direct interaction with filamins modulates the stability and plasma membrane expression of CFTR. J Clin Invest (2007) 1.29
Side-polished fiber Bragg grating hydrogen sensor with WO3-Pd composite film as sensing materials. Opt Express (2011) 1.28
PredUs: a web server for predicting protein interfaces using structural neighbors. Nucleic Acids Res (2011) 1.25
Ultrasonographic measures of cardiovascular disease risk in antiretroviral treatment-naive individuals with HIV infection. AIDS (2013) 1.23
Investigating the predictability of essential genes across distantly related organisms using an integrative approach. Nucleic Acids Res (2010) 1.21
Resveratrol suppresses the angiogenesis and tumor growth of gliomas in rats. Clin Cancer Res (2004) 1.21
Intracavernous transplantation of bone marrow-derived mesenchymal stem cells restores erectile function of streptozocin-induced diabetic rats. J Sex Med (2010) 1.20
miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells. Oncol Rep (2013) 1.18
Development of a porcine bladder acellular matrix with well-preserved extracellular bioactive factors for tissue engineering. Tissue Eng Part C Methods (2010) 1.15
IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation. J Immunol (2013) 1.14
Mitochondrial contagion induced by Parkin deficiency in Drosophila hearts and its containment by suppressing mitofusin. Circ Res (2013) 1.13
Synergistic effect of TGF-beta superfamily members on the induction of Foxp3+ Treg. Eur J Immunol (2010) 1.13
Zhihengliuella alba sp. nov., and emended description of the genus Zhihengliuella. Int J Syst Evol Microbiol (2009) 1.12
Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency. Proc Natl Acad Sci U S A (2010) 1.12
The Msx1 Homeoprotein Recruits Polycomb to the Nuclear Periphery during Development. Dev Cell (2011) 1.11
Analysis of the PC12 cell transcriptome after differentiation with pituitary adenylate cyclase-activating polypeptide (PACAP). J Neurochem (2002) 1.09
Brightness analysis by Z-scan fluorescence fluctuation spectroscopy for the study of protein interactions within living cells. Biophys J (2010) 1.09
Localization of lipids in the aortic wall with imaging TOF-SIMS. Biochim Biophys Acta (2006) 1.08
STAT6 specific shRNA inhibits proliferation and induces apoptosis in colon cancer HT-29 cells. Cancer Lett (2006) 1.08
Down-regulation of BMI-1 cooperates with artemisinin on growth inhibition of nasopharyngeal carcinoma cells. J Cell Biochem (2011) 1.08
The prognostic value of vascular endothelial growth factor in ovarian cancer: a systematic review and meta-analysis. Gynecol Oncol (2012) 1.06
Identification of novel AR-targeted microRNAs mediating androgen signalling through critical pathways to regulate cell viability in prostate cancer. PLoS One (2013) 1.06
Body composition, soluble markers of inflammation, and bone mineral density in antiretroviral therapy-naive HIV-1-infected individuals. J Acquir Immune Defic Syndr (2013) 1.05
Combined strategy of mesenchymal stem cell injection with vascular endothelial growth factor gene therapy for the treatment of diabetes-associated erectile dysfunction. J Androl (2011) 1.05
Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice. Cancer Lett (2009) 1.05
HULC and Linc00152 Act as Novel Biomarkers in Predicting Diagnosis of Hepatocellular Carcinoma. Cell Physiol Biochem (2015) 1.05
Engineering of acetyl-CoA metabolism for the improved production of polyhydroxybutyrate in Saccharomyces cerevisiae. AMB Express (2012) 1.04
Diversion of flux toward sesquiterpene production in Saccharomyces cerevisiae by fusion of host and heterologous enzymes. Appl Environ Microbiol (2010) 1.03
Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene α-santalene in a fed-batch mode. Metab Eng (2012) 1.03
Chronic encapsulated intracerebral haematoma. J Clin Neurosci (2006) 1.03
Molecular clustering of endometrial carcinoma based on estrogen-induced gene expression. Cancer Biol Ther (2009) 1.02
Arabidopsis WRKY45 transcription factor activates PHOSPHATE TRANSPORTER1;1 expression in response to phosphate starvation. Plant Physiol (2014) 1.02
Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition. BMC Cancer (2014) 1.01
Improving production of malonyl coenzyme A-derived metabolites by abolishing Snf1-dependent regulation of Acc1. MBio (2014) 1.01
Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance. Proc Natl Acad Sci U S A (2014) 1.01
Improving biobutanol production in engineered Saccharomyces cerevisiae by manipulation of acetyl-CoA metabolism. J Ind Microbiol Biotechnol (2013) 1.01
High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer. Int J Cancer (2010) 1.01
IL-22 is related to development of human colon cancer by activation of STAT3. BMC Cancer (2013) 1.01
Radiation-induced temporary alopecia after embolization of cerebral arteriovenous malformations. Clin Neurol Neurosurg (2003) 1.01
Imaging of lipids in human adipose tissue by cluster ion TOF-SIMS. Microsc Res Tech (2007) 1.01
Omega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescents. Atherosclerosis (2010) 1.01
Coincident elevation of cAMP and calcium influx by PACAP-27 synergistically regulates vasoactive intestinal polypeptide gene transcription through a novel PKA-independent signaling pathway. J Neurosci (2002) 1.01
Wireless amplified nuclear MR detector (WAND) for high-spatial-resolution MR imaging of internal organs: preclinical demonstration in a rodent model. Radiology (2013) 1.01
Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats. Toxicology (2010) 1.00
Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells. Proc Natl Acad Sci U S A (2012) 1.00
Arsenic contamination and potential health risk implications at an abandoned tungsten mine, southern China. Environ Pollut (2009) 0.99
Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities. Antiviral Res (2006) 0.99
OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion. Oncol Rep (2012) 0.98
New methods for finding common insertion sites and co-occurring common insertion sites in transposon- and virus-based genetic screens. Nucleic Acids Res (2012) 0.98
Stigmatizing attitudes and behaviors toward PLHA in rural China. AIDS Care (2010) 0.98
High physiological omega-3 Fatty Acid supplementation affects muscle Fatty Acid composition and glucose and insulin homeostasis in obese adolescents. J Nutr Metab (2012) 0.97
The abundance and host-seeking behavior of culicine species (Diptera: Culicidae) and Anopheles sinensis in Yongcheng city, People's Republic of China. Parasit Vectors (2011) 0.97
A serine sensor for multicellularity in a bacterium. Elife (2013) 0.97
Sylvian fissure dermoid cyst with intratumoral hemorrhage: case report. Clin Neurol Neurosurg (2004) 0.96
FAT10 mediates the effect of TNF-α in inducing chromosomal instability. J Cell Sci (2011) 0.96
MicroRNA-224 targets SMAD family member 4 to promote cell proliferation and negatively influence patient survival. PLoS One (2013) 0.96
Low expression of stathmin in tumor predicts high response to neoadjuvant chemotherapy with docetaxel-containing regimens in locally advanced breast cancer. Genet Test Mol Biomarkers (2012) 0.95
Crystal structure of 70S ribosome with both cognate tRNAs in the E and P sites representing an authentic elongation complex. PLoS One (2013) 0.95
Arabidopsis RAV1 transcription factor, phosphorylated by SnRK2 kinases, regulates the expression of ABI3, ABI4, and ABI5 during seed germination and early seedling development. Plant J (2014) 0.95
miR-22 promotes HBV-related hepatocellular carcinoma development in males. Clin Cancer Res (2011) 0.95
Primary tumor standardized uptake value measured on F18-Fluorodeoxyglucose positron emission tomography is of prediction value for survival and local control in non-small-cell lung cancer receiving radiotherapy: meta-analysis. J Thorac Oncol (2014) 0.94
TOF-SIMS analysis of lipid accumulation in the skeletal muscle of ob/ob mice. Obesity (Silver Spring) (2008) 0.94
Expression of leptin receptor gene in developing and adult zebrafish. Gen Comp Endocrinol (2009) 0.93
Racial differences in response to antiretroviral therapy for HIV infection: an AIDS clinical trials group (ACTG) study analysis. Clin Infect Dis (2013) 0.93
Lipopolysaccharide preconditioning protects hepatocytes from ischemia/reperfusion injury (IRI) through inhibiting ATF4-CHOP pathway in mice. PLoS One (2013) 0.93