Reversible modulation of liver hydroxymethylglutaryl CoA reductase.

PubWeight™: 1.11‹?› | Rank: Top 10%

🔗 View Article (PMID 216867)

Published in Life Sci on December 31, 1978

Authors

D M Gibson, T S Ingebritsen

Articles citing this

Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase. J Clin Invest (1980) 2.26

Tumor necrosis factor-alpha stimulates hepatic lipogenesis in the rat in vivo. J Clin Invest (1987) 1.95

Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in murine epidermis. Modulation of enzyme content and activation state by barrier requirements. J Clin Invest (1990) 1.06

Can phosphorylation of phosphatidate phosphohydrolase by a cyclic AMP-dependent mechanism regulate its activity and subcellular distribution and control hepatic glycerolipid synthesis? Biochem J (1984) 1.03

Characterization and regulation of reductase kinase, a protein kinase that modulates the enzymic activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Proc Natl Acad Sci U S A (1979) 0.93

Modulation of 3-hydroxy-3-methylglutaryl-CoA reductase by changes in microsomal cholesterol content or phospholipid composition. Proc Natl Acad Sci U S A (1987) 0.84

Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in rat liver and Morris hepatomas 5123C, 9618A and 5123t.c. Biochem J (1982) 0.82

Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mol Cell Biochem (1983) 0.77

Diurnal variation in the fraction of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the active form in the mammary gland of the lactating rat. Biochem J (1986) 0.76

Role of protein synthesis in the carbohydrate-induced changes in the activities of acetyl-CoA carboxylase and hydroxymethylglutaryl-CoA reductase in cultured rat hepatocytes. Biochem J (1985) 0.75

Articles by these authors

Evidence of functional lymphocytes in some (leaky) scid mice. J Exp Med (1988) 3.09

Discovery of a Ca2+- and calmodulin-dependent protein phosphatase: probable identity with calcineurin (CaM-BP80). FEBS Lett (1982) 2.75

Protein phosphatases: properties and role in cellular regulation. Science (1983) 2.61

Mutant immunoglobulin genes have repetitive DNA elements inserted into their intervening sequences. Proc Natl Acad Sci U S A (1982) 2.44

Pharmacodynamic effects and pharmacokinetics of atorvastatin after administration to normocholesterolemic subjects in the morning and evening. J Clin Pharmacol (1996) 2.37

Evidence for close linkage of a mouse light chain marker with the Ly-2,3 locus. J Immunol (1978) 2.34

The protein phosphatases involved in cellular regulation. 1. Classification and substrate specificities. Eur J Biochem (1983) 2.31

Symposium on microbial changes in foods. Bacteria active in the spoilage of certain sea foods. J Appl Bacteriol (1971) 2.01

The protein phosphatases involved in cellular regulation. 6. Measurement of type-1 and type-2 protein phosphatases in extracts of mammalian tissues; an assessment of their physiological roles. Eur J Biochem (1983) 1.85

Taxonomic position and seasonal variations in marine neritic environment of some gram-negative antibiotic-producing bacteria. J Gen Microbiol (1975) 1.74

Short-term effects of insulin and glucagon on lipid synthesis in isolated rat hepatocytes. Covariance of acetyl-CoA carboxylase activity and the rate of 3H2O incorporation into fatty acids. FEBS Lett (1978) 1.59

Protein phosphatase 2A subunit assembly: the catalytic subunit carboxy terminus is important for binding cellular B subunit but not polyomavirus middle tumor antigen. Oncogene (1997) 1.57

Sequence diversity within a subgroup of mouse immunoglobulin kappa chains controlled by the IgK-Ef2 locus. J Exp Med (1981) 1.55

Extracellular phytase (E.C. 3.1.3.8) from Aspergillus ficuum NRRL 3135: purification and characterization. Prep Biochem (1987) 1.54

Electronic measurement of bacterial growth. J Phys E (1978) 1.50

Multiple-dose pharmacokinetics, pharmacodynamics, and safety of atorvastatin, an inhibitor of HMG-CoA reductase, in healthy subjects. Clin Pharmacol Ther (1996) 1.48

The kinetics of taxoid accumulation in cell suspension cultures of Taxus following elicitation with methyl jasmonate. Biotechnol Bioeng (1999) 1.44

Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and wth protein fractions of rat liver cytosol. Biochem Biophys Res Commun (1973) 1.38

Tuberculosis Prevention. Can Med Assoc J (1945) 1.38

Cytochrome P450-catalyzed hydroxylation of taxa-4(5),11(12)-diene to taxa-4(20),11(12)-dien-5alpha-ol: the first oxygenation step in taxol biosynthesis. Chem Biol (1996) 1.34

Purification and properties of a novel cytochrome: flavocytochrome c from Shewanella putrefaciens. Biochem J (1994) 1.33

The txtAB genes of the plant pathogen Streptomyces acidiscabies encode a peptide synthetase required for phytotoxin thaxtomin A production and pathogenicity. Mol Microbiol (2000) 1.30

Reversible modulation of the activities of both liver microsomal hydroxymethylglutaryl coenzyme A reductase and its inactivating enzyme. Evidence for regulation by phosphorylation-dephosphorylation. Biochem Biophys Res Commun (1978) 1.29

The protein phosphatases involved in cellular regulation. 5. Purification and properties of a Ca2+/calmodulin-dependent protein phosphatase (2B) from rabbit skeletal muscle. Eur J Biochem (1983) 1.28

Regulation of rhodopsin dephosphorylation by arrestin. J Biol Chem (1989) 1.27

A device for recording automatic audio tape recording. J Appl Behav Anal (1971) 1.24

Identification of protein phosphatase 1 in synaptic junctions: dephosphorylation of endogenous calmodulin-dependent kinase II and synapse-enriched phosphoproteins. J Neurosci (1985) 1.23

Phosphotyrosyl-protein phosphatases. I. Separation of multiple forms from bovine brain and purification of the major form to near homogeneity. J Biol Chem (1989) 1.22

Modulation of hydroxymethylglutaryl-CoA reductase activity, reductase kinase activity, and cholesterol synthesis in rat hepatocytes in response to insulin and glucagon. J Biol Chem (1979) 1.19

A guanosine triphosphate-dependent acyl coenzyme A synthetase from rat liver mitochondria. J Biol Chem (1967) 1.19

Inhibition of hyperlipogenesis with puromycin or actinomycin D. Biochim Biophys Acta (1965) 1.18

Phosphorylation of native 97-kDa 3-hydroxy-3-methylglutaryl-coenzyme A reductase from rat liver. Impact on activity and degradation of the enzyme. J Biol Chem (1989) 1.17

Subcellular Localizations of Two Dolichos biflorus Lectins. Plant Physiol (1984) 1.15

Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: implications for cinnamon regulation of insulin signalling. Horm Res (1998) 1.14

Protein (serine and threonine) phosphate phosphatases. Methods Enzymol (1984) 1.13

Protein tyrosine phosphatase stimulates Ca(2+)-dependent amylase secretion from pancreatic acini. J Biol Chem (1991) 1.10

Antibody gene linkage studies in (NZB X C58) recombinant-inbred lines. J Immunol (1980) 1.09

pp54 microtubule-associated protein-2 kinase requires both tyrosine and serine/threonine phosphorylation for activity. J Biol Chem (1991) 1.08

The catalytic subunit of phosphatase 2A dephosphorylates phosphoopsin. Biochemistry (1989) 1.08

Microbiological quality and shelf life prediction of chilled fish. Int J Food Microbiol (1988) 1.07

Regulation of Xenopus laevis DNA topoisomerase I activity by phosphorylation in vitro. Biochemistry (1988) 1.07

Synthesis and degradation of the lipogenic enzymes of rat liver. Adv Enzyme Regul (1972) 1.06

Purification and characterization of acid phosphatase from cotyledons of germinating soybean seeds. Arch Biochem Biophys (1988) 1.06

Influence of respiratory substrate on the cytochrome content of Shewanella putrefaciens. FEMS Microbiol Lett (1990) 1.05

Lack of correlation between the rate of cholesterol biosynthesis and the activity of 3-hydroxy-3-methylgutaryl coenzyme A reductase in rats and in fibroblasts treated with ML-236B. Biochem Biophys Res Commun (1978) 1.03

The protein phosphatases involved in cellular regulation. 2. Glycogen metabolism. Eur J Biochem (1983) 1.01

Acidic residues are involved in substrate recognition by two soluble protein tyrosine phosphatases, PTP-5 and rrbPTP-1. Biochemistry (1993) 1.00

Phosphorylation and inactivation of protein phosphatase 1 by pp60v-src. Proc Natl Acad Sci U S A (1986) 1.00

The protein phosphatases involved in cellular regulation. 3. Fatty acid synthesis, cholesterol synthesis and glycolysis/gluconeogenesis. Eur J Biochem (1983) 0.98

Ef2: a new LY-3-linked light-chain marker expressed in normal mouse serum immunoglobulin. J Exp Med (1979) 0.96

Iturin levels on wheat spikes linked to biological control of Fusarium head blight by Bacillus amyloliquefaciens. Phytopathology (2013) 0.96

Food increases the bioavailability of isotretinoin. J Clin Pharmacol (1984) 0.96

Deletions in immunoglobulin polypeptide chains as evidence for breakage and repair in DNA. Science (1971) 0.96

Evidence for 65 electrophoretically distinct groups of light chains in BALB/c and NZB myelomas. Mol Immunol (1984) 0.96

Phosphorylation of microsomal HMG CoA reductase increases susceptibility to proteolytic degradation in vitro. Biochem Biophys Res Commun (1984) 0.95

The protein phosphatases involved in cellular regulation. 4. Classification of two homogeneous myosin light chain phosphatases from smooth muscle as protein phosphatase-2A1 and 2C, and a homogeneous protein phosphatase from reticulocytes active on protein synthesis initiation factor eIF-2 as protein phosphatase-2A2. Eur J Biochem (1983) 0.94

Involvement of a cytochrome P450 monooxygenase in thaxtomin A biosynthesis by Streptomyces acidiscabies. J Bacteriol (2002) 0.94

Phosphorylation and degradation of HMG CoA reductase. Adv Enzyme Regul (1989) 0.92

Limited clonal diversity of serum immunoglobulin in leaky scid mice. Curr Top Microbiol Immunol (1989) 0.92

A simple method for enhancing paclitaxel release from Taxus canadensis cell suspension cultures utilizing cell wall digesting enzymes. Plant Cell Rep (2003) 0.92

The Potential of Thiarubrine C as a Nematicidal Agent against Plant- parasitic Nematodes. J Nematol (1998) 0.92

The organization of immunoglobulin variable kappa chain genes on mouse chromosome 6. Immunogenetics (1986) 0.92

Conversion of protein phosphatase 1 catalytic subunit to a Mn(2+)-dependent enzyme impairs its regulation by inhibitor 1. Biochemistry (1997) 0.91

Regulation of liver hydroxymethylglutaryl-CoA reductase by a bicyclic phosphorylation system. J Biol Chem (1981) 0.91

Structurally different members of the okadaic acid class selectively inhibit protein serine/threonine but not tyrosine phosphatase activity. Toxicon (1992) 0.91

Positive identification of a lambda gt11 clone containing a region of fungal phytase gene by immunoprobe and sequence verification. Appl Microbiol Biotechnol (1991) 0.90

Thiophosphorylated substrate analogs are potent active site-directed inhibitors of protein-tyrosine phosphatases. Anal Biochem (1994) 0.90

A major group of mouse kappa chains controlled by the chromosome 6 locus, IgK-Ef2. J Exp Med (1980) 0.90

Interaction and well-being in old age: is it quantity or quality that counts? Int J Aging Hum Dev (1987) 0.90

Oxidation of long chain fatty acids by rat liver mitochondria. J Biol Chem (1967) 0.90

Characterization of allelic V kappa-1 region genes in inbred strains of mice. J Immunol (1989) 0.89

Short-term regulation of hydroxymethylglutaryl coenzyme A reductase by reversible phosphorylation: modulation of reductase phosphatase in rat hepatocytes. Adv Enzyme Regul (1982) 0.89

Influence of lecithin on the activity of the GTP-dependent acyl-coA synthetase. Biochem Biophys Res Commun (1967) 0.89

A rapid method for purifying bacterial deoxyribonucleic acid. J Appl Bacteriol (1979) 0.88

Selective dampening of lipogenic enzymes of liver by exogenous polyunsaturated fatty acids. Biochem Biophys Res Commun (1970) 0.88

Unique V kappa group associated with two mouse L chain genetic markers. Proc Natl Acad Sci U S A (1981) 0.88

Intraabdominal abscess after penetrating abdominal trauma. Am J Surg (1981) 0.88

Interferon kinetics and adverse reactions after intravenous, intramuscular, and subcutaneous injection. Clin Pharmacol Ther (1984) 0.88

Effect of food on the pharmacodynamics and pharmacokinetics of atorvastatin, an inhibitor of HMG-CoA reductase. Eur J Drug Metab Pharmacokinet (2001) 0.86

Lipid Composition of Cyst Stages of Globodera rostochiensis. J Nematol (1995) 0.86

Polymorphism of kappa variable region (V kappa-1) genes in inbred mice: relationship to the Ig kappa-Ef2 serum light chain marker. J Immunol (1985) 0.85

Taxol production and taxadiene synthase activity in Taxus canadensis cell suspension cultures. Arch Biochem Biophys (1997) 0.84

Light chain isotype regulation in the horse. Characterization of Ig kappa genes. J Immunol (1994) 0.84

Casein kinase II stimulates Xenopus laevis DNA topoisomerase I by physical association. Biochemistry (1994) 0.84

Continuing evaluation of the Queen's University tactile vocoder II: Identification of open set sentences and tracking narrative. J Rehabil Res Dev (1986) 0.84

Isolation of labeled 9-dihydrobaccatin III and related taxoids from cell cultures of taxuscell cultures of taxus canadensis elicited with m. J Nat Prod (1999) 0.83

Recombination between kappa chain genetic markers and the Lyt-3 locus. Immunogenetics (1983) 0.83

Continuing evaluation of the Queen's University tactile vocoder. I: Identification of open set words. J Rehabil Res Dev (1986) 0.82

Regulation of the metabolism of rabbit liver mitochondria by long chain fatty acids and other uncouplers of oxidative phosphorylation. J Biol Chem (1969) 0.82

Polyketide synthase genes in insect- and nematode-associated fungi. Appl Microbiol Biotechnol (2001) 0.81

Effects of phosphorylation of protein phosphatase 1 by pp60v-src on the interaction of the enzyme with substrates and inhibitor proteins. Biochim Biophys Acta (1987) 0.81

Reconstitution of scid mice by injection of varying numbers of normal fetal liver cells into scid neonates. Curr Top Microbiol Immunol (1989) 0.80

Recombination between kappa chain genetic markers in the mouse. Immunogenetics (1984) 0.80

L chain isotype regulation in horse. I. Characterization of Ig lambda genes. J Immunol (1992) 0.80

Pharmacokinetics of recombinant leukocyte A interferon following various routes and modes of administration to the dog. J Interferon Res (1985) 0.80

Analysis of T cell receptor beta chain expression by isoelectric focusing following gene amplification and in vitro translation. J Immunol Methods (1995) 0.79

Visualization of peroxidase isozymes with eugenol, a noncarcinogenic substrate. Anal Biochem (1977) 0.79