Published in BMC Syst Biol on May 04, 2011
GSTCD and INTS12 regulation and expression in the human lung. PLoS One (2013) 0.94
Identification of microRNA as sepsis biomarker based on miRNAs regulatory network analysis. Biomed Res Int (2014) 0.92
The landscape of antisense gene expression in human cancers. Genome Res (2015) 0.91
Regulation of Interferon-Stimulated Gene BST2 by a lncRNA Transcribed from a Shared Bidirectional Promoter. Front Immunol (2015) 0.90
Bidirectional promoters as important drivers for the emergence of species-specific transcripts. PLoS One (2013) 0.88
The preservation of bidirectional promoter architecture in eukaryotes: what is the driving force? BMC Syst Biol (2012) 0.84
Functional networking of human divergently paired genes (DPGs). PLoS One (2013) 0.83
Bidirectional promoters in seed development and related hormone/stress responses. BMC Plant Biol (2013) 0.82
Deep sequencing reveals a novel class of bidirectional promoters associated with neuronal genes. BMC Genomics (2014) 0.81
Positive Selection on a Regulatory Insertion-Deletion Polymorphism in FADS2 Influences Apparent Endogenous Synthesis of Arachidonic Acid. Mol Biol Evol (2016) 0.81
A study on promoter characteristics of head-to-head genes in Saccharomyces cerevisiae. BMC Genomics (2012) 0.79
Identification of regulatory regions of bidirectional genes in cervical cancer. BMC Med Genomics (2013) 0.79
LuFLA1PRO and LuBGAL1PRO promote gene expression in the phloem fibres of flax (Linum usitatissimum). Plant Cell Rep (2013) 0.77
Novel Biomarker MicroRNAs for Subtyping of Acute Coronary Syndrome: A Bioinformatics Approach. Biomed Res Int (2016) 0.75
Characteristics of Antisense Transcript Promoters and the Regulation of Their Activity. Int J Mol Sci (2015) 0.75
Genetic variability of the activity of bidirectional promoters: a pilot study in bovine muscle. DNA Res (2017) 0.75
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature (2005) 31.60
CpG islands in vertebrate genomes. J Mol Biol (1987) 23.16
TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes. Nucleic Acids Res (2006) 22.20
JASPAR: an open-access database for eukaryotic transcription factor binding profiles. Nucleic Acids Res (2004) 19.32
Genome-wide analysis of mammalian promoter architecture and evolution. Nat Genet (2006) 17.19
Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci U S A (2002) 12.33
An abundance of bidirectional promoters in the human genome. Genome Res (2004) 5.90
A new generation of JASPAR, the open-access repository for transcription factor binding site profiles. Nucleic Acids Res (2006) 4.32
Bidirectional gene organization: a common architectural feature of the human genome. Cell (2002) 3.47
Coexpression of neighboring genes in the genome of Arabidopsis thaliana. Genome Res (2004) 2.52
Transcription factor binding and modified histones in human bidirectional promoters. Genome Res (2007) 2.40
Regulation of adjacent yeast genes. Trends Genet (2000) 2.12
E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ (1998) 1.96
Isolation and characterisation of the NBR2 gene which lies head to head with the human BRCA1 gene. Hum Mol Genet (1997) 1.50
The bidirectional promoter of the divergently transcribed mouse Surf-1 and Surf-2 genes. Mol Cell Biol (1991) 1.50
Alpha 1(IV) and alpha 2(IV) collagen genes are regulated by a bidirectional promoter and a shared enhancer. Proc Natl Acad Sci U S A (1988) 1.44
Characterization of a bidirectional promoter shared between two human genes related to aging: SIRT3 and PSMD13. Genomics (2006) 1.21
Origins of bidirectional promoters: computational analyses of intergenic distance in the human genome. Mol Biol Evol (2003) 1.20
Identification of the functional elements in the bidirectional promoter of the mouse O-sialoglycoprotein endopeptidase and APEX nuclease genes. Biochem Biophys Res Commun (2002) 1.18
Coexpression of two closely linked avian genes for purine nucleotide synthesis from a bidirectional promoter. Mol Cell Biol (1993) 1.11
Analysis of the chicken GPAT/AIRC bidirectional promoter for de novo purine nucleotide synthesis. J Biol Chem (1995) 1.08
A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: amino acid sequence, structure and expression studies. Hum Mol Genet (1996) 1.06
The Surf-1 and Surf-2 genes and their essential bidirectional promoter elements are conserved between mouse and human. DNA Cell Biol (1994) 1.00
Identification of functional elements in the murine Gabp alpha/ATP synthase coupling factor 6 bi-directional promoter. Gene (2005) 0.99
Structural organization and promoter analysis of murine heat shock transcription factor-1 gene. J Biol Chem (1998) 0.99
Alternate activation of two divergently transcribed mouse genes from a bidirectional promoter is linked to changes in histone modification. J Biol Chem (2002) 0.99
Two non-homologous brain diseases-related genes, SERPINI1 and PDCD10, are tightly linked by an asymmetric bidirectional promoter in an evolutionarily conserved manner. BMC Mol Biol (2007) 0.98
Cross-species mapping of bidirectional promoters enables prediction of unannotated 5' UTRs and identification of species-specific transcripts. BMC Genomics (2009) 0.91
Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma. BMC Mol Biol (2009) 0.89
COTRASIF: conservation-aided transcription-factor-binding site finder. Nucleic Acids Res (2009) 0.89
Identification of functional elements in the bidirectional promoter of the mouse Nthl1 and Tsc2 genes. Biochem Biophys Res Commun (2000) 0.87
Silencing of LRRC49 and THAP10 genes by bidirectional promoter hypermethylation is a frequent event in breast cancer. Int J Oncol (2008) 0.87
Cooperative and competitive interactions of regulatory elements are involved in the control of divergent transcription of human Col4A1 and Col4A2 genes. FEBS Lett (1997) 0.83
Cooperation between NRF-2 and YY-1 transcription factors is essential for triggering the expression of the PREPL-C2ORF34 bidirectional gene pair. BMC Mol Biol (2009) 0.82
The Pxmp2 and PoleI genes are linked by a bidirectional promoter in an evolutionary conserved fashion. Gene (2003) 0.81
NF-Y influences directionality of transcription from the bidirectional Mrps12/Sarsm promoter in both mouse and human cells. Biochim Biophys Acta (2009) 0.80
A practical comparison of de novo genome assembly software tools for next-generation sequencing technologies. PLoS One (2011) 2.55
Performance comparison and evaluation of software tools for microRNA deep-sequencing data analysis. Nucleic Acids Res (2012) 1.80
Translational biomedical informatics in the cloud: present and future. Biomed Res Int (2013) 1.28
Biomedical text mining and its applications in cancer research. J Biomed Inform (2012) 1.22
Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family. J Biol Chem (2003) 1.19
Identification of novel microRNA regulatory pathways associated with heterogeneous prostate cancer. BMC Syst Biol (2013) 1.12
Identifying novel prostate cancer associated pathways based on integrative microarray data analysis. Comput Biol Chem (2011) 1.08
Characterization of CA XV, a new GPI-anchored form of carbonic anhydrase. Biochem J (2005) 1.07
Clear cell renal cell carcinoma associated microRNA expression signatures identified by an integrated bioinformatics analysis. J Transl Med (2013) 1.05
Genome wide analysis of pathogenic SH2 domain mutations. Proteins (2008) 1.05
Punicalagin inhibits inflammation in LPS-induced RAW264.7 macrophages via the suppression of TLR4-mediated MAPKs and NF-κB activation. Inflammation (2014) 1.01
Translational bioinformatics for diagnostic and prognostic prediction of prostate cancer in the next-generation sequencing era. Biomed Res Int (2013) 0.93
Sustained mechanical release of dexamethasone sodium phosphate from a foldable capsular vitreous body. Invest Ophthalmol Vis Sci (2009) 0.93
Technical standards of a foldable capsular vitreous body in terms of mechanical, optical, and biocompatible properties. Artif Organs (2010) 0.93
Post genome-wide association studies functional characterization of prostate cancer risk loci. BMC Genomics (2013) 0.91
Genome-scale analysis of the metabolic networks of oleaginous Zygomycete fungi. Gene (2013) 0.91
Integrative analysis reveals disease-associated genes and biomarkers for prostate cancer progression. BMC Med Genomics (2014) 0.91
Two functional microRNA-126s repress a novel target gene p21-activated kinase 1 to regulate vascular integrity in zebrafish. Circ Res (2010) 0.90
The protective effect of the recombinant 53-kDa protein of Trichinella spiralis on experimental colitis in mice. Dig Dis Sci (2011) 0.90
Profiling the repertoire of T-cell receptor beta-chain variable genes in peripheral blood lymphocytes from subjects who have recovered from acute hepatitis B virus infection. Cell Mol Immunol (2014) 0.90
Immunosuppressive effects of ginsenoside-Rd on skin allograft rejection in rats. J Surg Res (2011) 0.89
Molecular signature of cancer at gene level or pathway level? Case studies of colorectal cancer and prostate cancer microarray data. Comput Math Methods Med (2013) 0.88
Adsorption of double-stranded DNA to graphene oxide preventing enzymatic digestion. Nanoscale (2011) 0.88
Structure-based prediction of the effects of a missense variant on protein stability. Amino Acids (2012) 0.87
Catalytic mechanism investigation of lysine-specific demethylase 1 (LSD1): a computational study. PLoS One (2011) 0.87
Combined SVM-CRFs for biological named entity recognition with maximal bidirectional squeezing. PLoS One (2012) 0.86
Computational analysis of microRNA function in heart development. Acta Biochim Biophys Sin (Shanghai) (2010) 0.86
Key regulators in prostate cancer identified by co-expression module analysis. BMC Genomics (2014) 0.86
Systematic investigation of global coordination among mRNA and protein in cellular society. BMC Genomics (2010) 0.85
The construction of an amino acid network for understanding protein structure and function. Amino Acids (2014) 0.84
The preservation of bidirectional promoter architecture in eukaryotes: what is the driving force? BMC Syst Biol (2012) 0.84
Gene cloning, expression, and localization of antigen 5 in the life cycle of Echinococcus granulosus. Parasitol Res (2011) 0.84
Origination of new immunological functions in the costimulatory molecule B7-H3: the role of exon duplication in evolution of the immune system. PLoS One (2011) 0.83
Effects of time point measurement on the reconstruction of gene regulatory networks. Molecules (2010) 0.83
Discovery and characterization of long intergenic non-coding RNAs (lincRNA) module biomarkers in prostate cancer: an integrative analysis of RNA-Seq data. BMC Genomics (2015) 0.83
Towards patterns tree of gene coexpression in eukaryotic species. Bioinformatics (2008) 0.83
InCoB2013 introduces Systems Biology as a major conference theme. BMC Syst Biol (2013) 0.83
Skewed T-cell receptor beta chain variable gene (TCRBV) usage among different clinical types of patients with chronic HBV infection. FEMS Immunol Med Microbiol (2012) 0.83
Wnt4, a pleiotropic signal for controlling cell polarity, basement membrane integrity, and antimüllerian hormone expression during oocyte maturation in the female follicle. FASEB J (2013) 0.83
Inhibitory effect of ginsenoside-Rd on carrageenan-induced inflammation in rats. Can J Physiol Pharmacol (2012) 0.82
Expression of RBMX after spinal cord injury in rats. J Mol Neurosci (2012) 0.82
Downgrading MELD improves the outcomes after liver transplantation in patients with acute-on-chronic hepatitis B liver failure. PLoS One (2012) 0.81
Investigation of the acetylation mechanism by GCN5 histone acetyltransferase. PLoS One (2012) 0.81
Identification and functional annotation of genome-wide ER-regulated genes in breast cancer based on ChIP-Seq data. Comput Math Methods Med (2012) 0.80
Review of MARCH-INSIDE & complex networks prediction of drugs: ADMET, anti-parasite activity, metabolizing enzymes and cardiotoxicity proteome biomarkers. Curr Drug Metab (2010) 0.80
Identifying novel glioma associated pathways based on systems biology level meta-analysis. BMC Syst Biol (2013) 0.80
Biocompatibility and retinal support of a foldable capsular vitreous body injected with saline or silicone oil implanted in rabbit eyes. Clin Experiment Ophthalmol (2011) 0.80
NF-Y influences directionality of transcription from the bidirectional Mrps12/Sarsm promoter in both mouse and human cells. Biochim Biophys Acta (2009) 0.80
Molecular cloning, expression, and characterization of cyclophilin A from Clonorchis sinensis. Parasitol Res (2011) 0.79
Schistosoma japonicum tegumental protein 20.8, role in reproduction through its calcium binding ability. Parasitol Res (2013) 0.79
Absolute quantification of histone PTM marks by MRM-based LC-MS/MS. Anal Chem (2014) 0.79
Spatiotemporal profile and essential role of RBM3 expression after spinal cord injury in adult rats. J Mol Neurosci (2014) 0.78
Diagnosis value of the serum amyloid A test in neonatal sepsis: a meta-analysis. Biomed Res Int (2013) 0.78
HBsAg as an important predictor of HBeAg seroconversion following antiviral treatment for HBeAg-positive chronic hepatitis B patients. J Transl Med (2014) 0.78
[Simultaneous determination of three coumarin constituents in roots of Peucedanum praeruptorum by RP-HPLC]. Zhongguo Zhong Yao Za Zhi (2009) 0.78
Pathway analysis of microRNAs in mouse heart development. Int J Bioinform Res Appl (2010) 0.78
The topology and dynamics of protein complexes: insights from intra- molecular network theory. Curr Protein Pept Sci (2013) 0.78
Deciphering oncogenic drivers: from single genes to integrated pathways. Brief Bioinform (2014) 0.77
Polyphenol extracts from Punica granatum and Terminalia chebula are anti-inflammatory and increase the survival rate of chickens challenged with Escherichia coli. Biol Pharm Bull (2014) 0.77
Translational bioinformatics and computational systems medicine. Comput Math Methods Med (2013) 0.76
Virtual screening and biological evaluation of novel small molecular inhibitors against protein arginine methyltransferase 1 (PRMT1). Org Biomol Chem (2014) 0.76
A systems biology perspective on rational design of peptide vaccine against virus infections. Curr Top Med Chem (2012) 0.76
Molecular dynamic simulation to explore the molecular basis of Btk-PH domain interaction with Ins(1,3,4,5)P4. ScientificWorldJournal (2013) 0.76
SVR_CAF: an integrated score function for detecting native protein structures among decoys. Proteins (2013) 0.76
The Expression of CUGBP1 After Spinal Cord Injury in Rats. Neurochem Res (2015) 0.76
Predictive value of serum ALT and T-cell receptor beta variable chain for HBeAg seroconversion in chronic hepatitis B patients during tenofovir treatment. Medicine (Baltimore) (2017) 0.75
Computational inference and analysis of genetic regulatory networks via a supervised combinatorial-optimization pattern. BMC Syst Biol (2010) 0.75
Clinical findings in 19 cases of invasive pulmonary aspergillosis with liver cirrhosis. Multidiscip Respir Med (2014) 0.75
Nuclear translocation of PKM2 modulates astrocyte proliferation via p27 and -catenin pathway after spinal cord injury. Cell Cycle (2015) 0.75
Successful treatment of multifoci nocardial brain abscesses: a case report and literature review. Medicine (Baltimore) (2015) 0.75
Evaluation of plasma exchange and continuous veno-venous hemofiltration for the treatment of severe avian influenza A (H7N9): a cohort study. Ther Apher Dial (2014) 0.75
Physical-layer network coding for passive optical interconnect in datacenter networks. Opt Express (2017) 0.75
Passive optical interconnects at top of the rack: offering high energy efficiency for datacenters. Opt Express (2015) 0.75
Multi-wavelength Transmission-Reflection Analysis for fiber monitoring. Opt Express (2014) 0.75
Review of computer-aided models for predicting collagen stability. Curr Comput Aided Drug Des (2011) 0.75
Computer-aided biomarker discovery for precision medicine: data resources, models and applications. Brief Bioinform (2017) 0.75
NGS-FC: A Next-Generation Sequencing Data Format Converter. IEEE/ACM Trans Comput Biol Bioinform (2017) 0.75
Full monitoring for long-reach TWDM passive optical networks. Opt Express (2016) 0.75
Effects of ACA Medicaid Expansions on Health Insurance Coverage and Labor Supply. J Policy Anal Manage (2017) 0.75
A Novel and Facile Method to Prepare Integrated Electrospun Nanofibrous Membrane with Soldered Junctions. J Nanosci Nanotechnol (2016) 0.75
Crosstalk of homocysteinylation, methylation and acetylation on histone H3. Analyst (2015) 0.75
[Therapeutic effect of heating and bandage treatment for chronic lymphedema of extremities accompanied with erysipelas: a report of 80 cases]. Zhonghua Zheng Xing Wai Ke Za Zhi (2015) 0.75