Translational control in oocyte development.

POS-1 Promotes Endo-mesoderm Development by Inhibiting the Cytoplasmic Polyadenylation of neg-1 mRNA. Dev Cell (2015) 1.38

Zygotic genome activation during the maternal-to-zygotic transition. Annu Rev Cell Dev Biol (2014) 1.30

Cooperativity in RNA-protein interactions: global analysis of RNA binding specificity. Cell Rep (2012) 1.22

Stable intronic sequence RNA (sisRNA), a new class of noncoding RNA from the oocyte nucleus of Xenopus tropicalis. Genes Dev (2012) 1.15

Germline stem cells: origin and destiny. Cell Stem Cell (2012) 1.04

A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins. Genes Dev (2014) 0.97

Identification of a conserved interface between PUF and CPEB proteins. J Biol Chem (2012) 0.90

PARP12, an interferon-stimulated gene involved in the control of protein translation and inflammation. J Biol Chem (2014) 0.90

Lariat intronic RNAs in the cytoplasm of Xenopus tropicalis oocytes. RNA (2014) 0.89

BTG4 is a meiotic cell cycle-coupled maternal-zygotic-transition licensing factor in oocytes. Nat Struct Mol Biol (2016) 0.89

The Maternal-to-Zygotic Transition During Vertebrate Development: A Model for Reprogramming. Curr Top Dev Biol (2015) 0.89

New insights into the regulation of RNP granule assembly in oocytes. Int Rev Cell Mol Biol (2012) 0.88

Extensive use of RNA-binding proteins in Drosophila sensory neuron dendrite morphogenesis. G3 (Bethesda) (2014) 0.81

Evidence against a germ plasm in the milkweed bug Oncopeltus fasciatus, a hemimetabolous insect. Biol Open (2013) 0.81

Positional RNA-Seq identifies candidate genes for phenotypic engineering of sexual traits. Front Zool (2015) 0.81

RNA-binding profiles of Drosophila CPEB proteins Orb and Orb2. Proc Natl Acad Sci U S A (2016) 0.81

On the Diversification of the Translation Apparatus across Eukaryotes. Comp Funct Genomics (2012) 0.79

RNA profiles of porcine embryos during genome activation reveal complex metabolic switch sensitive to in vitro conditions. PLoS One (2013) 0.76

New Phosphospecific Antibody Reveals Isoform-Specific Phosphorylation of CPEB3 Protein. PLoS One (2016) 0.76

Drosha protein levels are translationally regulated during Xenopus oocyte maturation. Mol Biol Cell (2014) 0.76

Localized Translation of gurken/TGF-α mRNA during Axis Specification Is Controlled by Access to Orb/CPEB on Processing Bodies. Cell Rep (2016) 0.76

Preovulatory Aging In Vivo and In Vitro Affects Maturation Rates, Abundance of Selected Proteins, Histone Methylation Pattern and Spindle Integrity in Murine Oocytes. PLoS One (2016) 0.75

CPEB1 restrains proliferation of Glioblastoma cells through the regulation of p27(Kip1) mRNA translation. Sci Rep (2016) 0.75

Long non-coding RNA exchange during the oocyte-to-embryo transition in mice. DNA Res (2017) 0.75

Novel functions for the RNA-binding protein ETR-1 in Caenorhabditis elegans reproduction and engulfment of germline apoptotic cell corpses. Dev Biol (2017) 0.75

microRNA functions. Annu Rev Cell Dev Biol (2007) 15.74

RISC assembly defects in the Drosophila RNAi mutant armitage. Cell (2004) 4.88

The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo. Nature (1989) 4.81

Induction of germ cell formation by oskar. Nature (1992) 4.23

The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo. EMBO J (1988) 4.19

Aubergine encodes a Drosophila polar granule component required for pole cell formation and related to eIF2C. Development (2001) 4.13

A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans. Nature (2002) 3.90

Translational regulation of oskar mRNA by bruno, an ovarian RNA-binding protein, is essential. Cell (1995) 3.71

CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses. Neuron (1998) 3.58

RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos. Cell (1991) 3.39

The ends of the affair: capping and polyadenylation. Nat Struct Biol (2000) 3.31

Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster. Proc Natl Acad Sci U S A (2007) 3.31

zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline. Dev Cell (2007) 3.29

A combinatorial code for CPE-mediated translational control. Cell (2008) 3.23

Me31B silences translation of oocyte-localizing RNAs through the formation of cytoplasmic RNP complex during Drosophila oogenesis. Development (2001) 3.22

Lipoxygenase mRNA silencing in erythroid differentiation: The 3'UTR regulatory complex controls 60S ribosomal subunit joining. Cell (2001) 3.19

Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA. Nature (2000) 3.12

Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element. Genes Dev (1989) 3.10

The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP. Cell (2008) 3.10

Symplekin and xGLD-2 are required for CPEB-mediated cytoplasmic polyadenylation. Cell (2004) 3.10

Maskin is a CPEB-associated factor that transiently interacts with elF-4E. Mol Cell (1999) 3.05

Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease. Nature (2006) 2.95

The 3'-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation. Genes Dev (1994) 2.95

Drosophila Brain Tumor is a translational repressor. Genes Dev (2001) 2.90

A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP. Cell (2005) 2.80

Poly(A) addition during maturation of frog oocytes: distinct nuclear and cytoplasmic activities and regulation by the sequence UUUUUAU. Genes Dev (1989) 2.78

Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles. Cell (2006) 2.77

Drosophila cup is an eIF4E binding protein that associates with Bruno and regulates oskar mRNA translation in oogenesis. Dev Cell (2004) 2.66

Transcription termination by nuclear RNA polymerases. Genes Dev (2009) 2.65

SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase. Dev Cell (2007) 2.64

The Drosophila SDE3 homolog armitage is required for oskar mRNA silencing and embryonic axis specification. Cell (2004) 2.59

Maelstrom, a Drosophila spindle-class gene, encodes a protein that colocalizes with Vasa and RDE1/AGO1 homolog, Aubergine, in nuage. Development (2003) 2.58

RNA recognition and translational regulation by a homeodomain protein. Nature (1996) 2.49

The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes. EMBO J (1998) 2.49

Opposing polymerase-deadenylase activities regulate cytoplasmic polyadenylation. Mol Cell (2006) 2.45

vasa is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst development. Development (1998) 2.44

Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation. Genes Dev (2006) 2.36

Cytoplasmic polyadenylation in development and beyond. Microbiol Mol Biol Rev (1999) 2.29

Coordinate initiation of Drosophila development by regulated polyadenylation of maternal messenger RNAs. Science (1994) 2.25

Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA. Cell (2002) 2.23

smaug protein represses translation of unlocalized nanos mRNA in the Drosophila embryo. Genes Dev (1996) 2.22

Phosphorylation of CPEB by Eg2 mediates the recruitment of CPSF into an active cytoplasmic polyadenylation complex. Mol Cell (2000) 2.21

A conserved role of a DEAD box helicase in mRNA masking. RNA (2001) 2.20

CPEB controls the cytoplasmic polyadenylation of cyclin, Cdk2 and c-mos mRNAs and is necessary for oocyte maturation in Xenopus. EMBO J (1996) 2.19

Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo. Curr Biol (2005) 2.18

Drosophila PTB promotes formation of high-order RNP particles and represses oskar translation. Genes Dev (2009) 2.16

RNA binding and translational suppression by bicoid. Nature (1996) 2.08

Differential mRNA translation and meiotic progression require Cdc2-mediated CPEB destruction. EMBO J (2002) 2.04

Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression. EMBO J (2003) 2.03

aubergine enhances oskar translation in the Drosophila ovary. Development (1996) 1.98

Oskar allows nanos mRNA translation in Drosophila embryos by preventing its deadenylation by Smaug/CCR4. Development (2006) 1.97

Translational repressor bruno plays multiple roles in development and is widely conserved. Genes Dev (1997) 1.95

Dissolution of the maskin-eIF4E complex by cytoplasmic polyadenylation and poly(A)-binding protein controls cyclin B1 mRNA translation and oocyte maturation. EMBO J (2002) 1.92

Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice. Dev Cell (2001) 1.90

Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression. Dev Cell (2007) 1.88

Distinct roles of two conserved Staufen domains in oskar mRNA localization and translation. EMBO J (2000) 1.87

Translational control of oskar generates short OSK, the isoform that induces pole plasma assembly. Development (1995) 1.85

Cutoff and aubergine mutations result in retrotransposon upregulation and checkpoint activation in Drosophila. Curr Biol (2007) 1.84

Biochemical identification of Xenopus Pumilio as a sequence-specific cyclin B1 mRNA-binding protein that physically interacts with a Nanos homolog, Xcat-2, and a cytoplasmic polyadenylation element-binding protein. J Biol Chem (2001) 1.81

Regulation of the meiotic cell cycle in oocytes. Curr Opin Cell Biol (2000) 1.80

Under arrest: cytostatic factor (CSF)-mediated metaphase arrest in vertebrate eggs. Genes Dev (2003) 1.80

CPEB interacts with an ovary-specific eIF4E and 4E-T in early Xenopus oocytes. J Biol Chem (2007) 1.79

Cytoplasmic poly(A) polymerases mediate cellular responses to S phase arrest. Proc Natl Acad Sci U S A (2002) 1.75

Meiotic maturation of mouse oocytes triggers the translation and polyadenylation of dormant tissue-type plasminogen activator mRNA. Genes Dev (1987) 1.74

Polyadenylation of maternal RNA of sea urchin eggs after fertilization. Proc Natl Acad Sci U S A (1973) 1.72

VASA mediates translation through interaction with a Drosophila yIF2 homolog. Mol Cell (2000) 1.72

Expression of a histone H1-like protein is restricted to early Xenopus development. Genes Dev (1988) 1.72

Cup is an eIF4E binding protein required for both the translational repression of oskar and the recruitment of Barentsz. J Cell Biol (2003) 1.70

Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene. Learn Mem (2004) 1.69

The Drosophila hnRNPA/B homolog, Hrp48, is specifically required for a distinct step in osk mRNA localization. Dev Cell (2004) 1.68

CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation. Genes Dev (2008) 1.66

A novel p34(cdc2)-binding and activating protein that is necessary and sufficient to trigger G(2)/M progression in Xenopus oocytes. Genes Dev (1999) 1.66

Antisense RNA directed against the 3' noncoding region prevents dormant mRNA activation in mouse oocytes. Science (1988) 1.63

Hrp48, a Drosophila hnRNPA/B homolog, binds and regulates translation of oskar mRNA. Dev Cell (2004) 1.57

PAP- and GLD-2-type poly(A) polymerases are required sequentially in cytoplasmic polyadenylation and oogenesis in Drosophila. Development (2008) 1.56

Interaction with eIF5B is essential for Vasa function during development. Development (2004) 1.55

Oocyte polarity depends on regulation of gurken by Vasa. Development (1998) 1.51

Specific isoforms of squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesis. Genes Dev (1999) 1.50

Musashi regulates the temporal order of mRNA translation during Xenopus oocyte maturation. EMBO J (2006) 1.49

Cap-dependent translational inhibition establishes two opposing morphogen gradients in Drosophila embryos. Curr Biol (2006) 1.47

Control of cellular senescence by CPEB. Genes Dev (2006) 1.47

Progesterone and insulin stimulation of CPEB-dependent polyadenylation is regulated by Aurora A and glycogen synthase kinase-3. Genes Dev (2004) 1.46

Hrb27C, Sqd and Otu cooperatively regulate gurken RNA localization and mediate nurse cell chromosome dispersion in Drosophila oogenesis. Development (2004) 1.46

Lighting up mRNA localization in Drosophila oogenesis. Development (2009) 1.46

The role of oocyte transcription, the 5'UTR, and translation repression and derepression in Drosophila gurken mRNA and protein localization. Mol Cell (1999) 1.44

RINGO/cdk1 and CPEB mediate poly(A) tail stabilization and translational regulation by ePAB. Genes Dev (2007) 1.42

A deadenylation negative feedback mechanism governs meiotic metaphase arrest. Nature (2008) 1.40

Localization-dependent translation requires a functional interaction between the 5' and 3' ends of oskar mRNA. Genes Dev (1998) 1.40

The Drosophila CPEB homolog, orb, is required for oskar protein expression in oocytes. Dev Biol (1999) 1.39

Poly(A)-independent regulation of maternal hunchback translation in the Drosophila embryo. Proc Natl Acad Sci U S A (2001) 1.38

Glorund, a Drosophila hnRNP F/H homolog, is an ovarian repressor of nanos translation. Dev Cell (2006) 1.38

Vasa promotes Drosophila germline stem cell differentiation by activating mei-P26 translation by directly interacting with a (U)-rich motif in its 3' UTR. Genes Dev (2009) 1.37

Role of p54 RNA helicase activity and its C-terminal domain in translational repression, P-body localization and assembly. Mol Biol Cell (2009) 1.36

Involvement of Xenopus Pumilio in the translational regulation that is specific to cyclin B1 mRNA during oocyte maturation. Mech Dev (2003) 1.35

An essential role for the RNA-binding protein Smaug during the Drosophila maternal-to-zygotic transition. Development (2009) 1.31

Overlapping but distinct RNA elements control repression and activation of nanos translation. Mol Cell (2000) 1.30

Wispy, the Drosophila homolog of GLD-2, is required during oogenesis and egg activation. Genetics (2008) 1.30

Reduced extinction of hippocampal-dependent memories in CPEB knockout mice. Learn Mem (2006) 1.29

Control of poly(A) polymerase level is essential to cytoplasmic polyadenylation and early development in Drosophila. EMBO J (2002) 1.29

Premature translation of oskar in oocytes lacking the RNA-binding protein bicaudal-C. Mol Cell Biol (1998) 1.28

Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature (2012) 3.13

A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP. Cell (2005) 2.80

mRNA helicases: the tacticians of translational control. Nat Rev Mol Cell Biol (2011) 2.41

Phosphorylation of eukaryotic translation initiation factor 4E is critical for growth. Mol Cell Biol (2002) 1.92

Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression. Dev Cell (2007) 1.88

Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells. Nature (2008) 1.77

Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies. Mol Biol Cell (2009) 1.60

Interaction with eIF5B is essential for Vasa function during development. Development (2004) 1.55

Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization. RNA (2009) 1.53

Isolation of new polar granule components in Drosophila reveals P body and ER associated proteins. Mech Dev (2008) 1.48

Cap-dependent translational inhibition establishes two opposing morphogen gradients in Drosophila embryos. Curr Biol (2006) 1.47

Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol (2005) 1.45

Nuclear retention of MBP mRNAs in the quaking viable mice. Neuron (2002) 1.41

Drosophila tudor is essential for polar granule assembly and pole cell specification, but not for posterior patterning. Genesis (2004) 1.41

Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster. Mol Cell Biol (2003) 1.41

Translational control in cellular and developmental processes. Nat Rev Genet (2012) 1.39

Vasa promotes Drosophila germline stem cell differentiation by activating mei-P26 translation by directly interacting with a (U)-rich motif in its 3' UTR. Genes Dev (2009) 1.37

Localization, anchoring and translational control of oskar, gurken, bicoid and nanos mRNA during Drosophila oogenesis. Fly (Austin) (2009) 1.32

VASA localization requires the SPRY-domain and SOCS-box containing protein, GUSTAVUS. Dev Cell (2002) 1.29

Tudor and its domains: germ cell formation from a Tudor perspective. Cell Res (2005) 1.12

Cytoplasmic polyadenylation element binding proteins in development, health, and disease. Annu Rev Cell Dev Biol (2014) 1.12

The development of germline stem cells in Drosophila. Methods Mol Biol (2008) 1.06

Spoltud-1 is a chromatoid body component required for planarian long-term stem cell self-renewal. Dev Biol (2009) 1.06

Fat facets interacts with vasa in the Drosophila pole plasm and protects it from degradation. Curr Biol (2003) 1.03

Nonmuscle myosin promotes cytoplasmic localization of PBX. Mol Cell Biol (2003) 1.03

The Drosophila poly(A) binding protein-interacting protein, dPaip2, is a novel effector of cell growth. Mol Cell Biol (2004) 1.01

Characterization of the Drosophila protein arginine methyltransferases DART1 and DART4. Biochem J (2004) 1.00

Bent out of shape: RNA unwinding by the DEAD-box helicase Vasa. Cell (2006) 0.98

Origins and evolution of the mechanisms regulating translation initiation in eukaryotes. Trends Biochem Sci (2009) 0.97

Regulation of Drosophila vasa in vivo through paralogous cullin-RING E3 ligase specificity receptors. Mol Cell Biol (2010) 0.95

Eukaryotic initiation factor 4E-3 is essential for meiotic chromosome segregation, cytokinesis and male fertility in Drosophila. Development (2012) 0.92

RanBPM regulates cell shape, arrangement, and capacity of the female germline stem cell niche in Drosophila melanogaster. J Cell Biol (2008) 0.90

Bicaudal-C associates with a Trailer Hitch/Me31B complex and is required for efficient Gurken secretion. Dev Biol (2009) 0.89

Kep1 interacts genetically with dredd/caspase-8, and kep1 mutants alter the balance of dredd isoforms. Proc Natl Acad Sci U S A (2003) 0.88

Stochastic variation: from single cells to superorganisms. HFSP J (2009) 0.84

Reduced cul-5 activity causes aberrant follicular morphogenesis and germ cell loss in Drosophila oogenesis. PLoS One (2010) 0.84

Murine homologues of the Drosophila gustavus gene are expressed in ovarian granulosa cells. Reproduction (2006) 0.83

Drosophila RNA binding proteins. Int Rev Cytol (2006) 0.83

The Bic-C family of developmental translational regulators. Comp Funct Genomics (2012) 0.83

Relationship between genome and epigenome--challenges and requirements for future research. BMC Genomics (2014) 0.82

Bruno negatively regulates germ cell-less expression in a BRE-independent manner. Mech Dev (2009) 0.81

The Distribution of eIF4E-Family Members across Insecta. Comp Funct Genomics (2012) 0.81

Mextli is a novel eukaryotic translation initiation factor 4E-binding protein that promotes translation in Drosophila melanogaster. Mol Cell Biol (2013) 0.79

The study of drugs for rare disorders: harnessing research contributions by Canadian academic institutions. J Popul Ther Clin Pharmacol (2014) 0.77

Map positions of third chromosomal female sterile and lethal mutations of Drosophila melanogaster. Genome (2004) 0.77

Vasa protein is localized in the germ cells and in the oocyte-associated pyriform follicle cells during early oogenesis in the lizard Podarcis sicula. Dev Genes Evol (2009) 0.77

A new model for translational regulation of specific mRNAs. Trends Biochem Sci (2006) 0.76

Breaking the A chain: regulating mRNAs in development through CCR4 deadenylase. F1000 Biol Rep (2009) 0.75

Genetic maps of the proximal half of chromosome arm 2L of Drosophila melanogaster. Genome (2007) 0.75

The 30th anniversary Crete fly meeting: from individual molecules to 12 genomes, and beyond. Fly (Austin) (2008) 0.75

Investigating translation initiation using Drosophila molecular genetics. Methods Enzymol (2007) 0.75