Published in J Pathol on June 27, 2011
Paternal age effect mutations and selfish spermatogonial selection: causes and consequences for human disease. Am J Hum Genet (2012) 1.78
Genome wide DNA methylation profiles provide clues to the origin and pathogenesis of germ cell tumors. PLoS One (2015) 1.45
Germline stem cells: toward the regeneration of spermatogenesis. Fertil Steril (2013) 0.96
Fluorescence- and magnetic-activated cell sorting strategies to isolate and enrich human spermatogonial stem cells. Fertil Steril (2014) 0.88
Testicular cancer: biology and biomarkers. Virchows Arch (2014) 0.86
Selfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly men. PLoS One (2012) 0.85
Morphological and immunohistochemical characterisation of seminomas in Norwegian dogs. Acta Vet Scand (2012) 0.85
Oncogenic functions of the cancer-testis antigen SSX on the proliferation, survival, and signaling pathways of cancer cells. PLoS One (2014) 0.84
Evaluation of candidate spermatogonial markers ID4 and GPR125 in testes of adult human cadaveric organ donors. Andrology (2014) 0.80
[Spermatocytic seminoma. A tumor with many faces]. Pathologe (2014) 0.79
Spermatocytic seminoma: toward further understanding of pathogenesis. J Pathol (2011) 0.78
Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline. PLoS One (2017) 0.75
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes. Nature (1986) 14.34
A genecentric Human Protein Atlas for expression profiles based on antibodies. Mol Cell Proteomics (2008) 6.45
Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature (1989) 5.68
The cancer/testis genes: review, standardization, and commentary. Cancer Immun (2004) 4.78
Testicular germ-cell tumours in a broader perspective. Nat Rev Cancer (2005) 3.75
Carcinoma-in-situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma. Int J Androl (1987) 2.61
The SSX-2 gene, which is involved in the t(X;18) translocation of synovial sarcomas, codes for the human tumor antigen HOM-MEL-40. Cancer Res (1996) 1.93
Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors. Nat Genet (2009) 1.72
Immunohistochemical profiling of germ cells within the human fetal testis: identification of three subpopulations. Biol Reprod (2004) 1.51
Pathobiological implications of the expression of markers of testicular carcinoma in situ by fetal germ cells. J Pathol (2004) 1.47
Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene. Cancer Res (2006) 1.41
The cycle of the seminiferous epithelium in man. Am J Anat (1963) 1.40
Monoclonal antibody 57B stains tumor tissues that express gene MAGE-A4. Int J Cancer (2000) 1.39
Renewal of spermatogonia in man. Am J Anat (1966) 1.36
Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte. Cancer Res (2009) 1.35
Developmental expression of POU5F1 (OCT-3/4) in normal and dysgenetic human gonads. Hum Reprod (2004) 1.34
Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus. Hum Mol Genet (1999) 1.31
[Not Available]. Rev Can Biol (1946) 1.28
Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines. Cancer Res (2000) 1.22
Spermatogonial stem cells: mouse and human comparisons. Birth Defects Res C Embryo Today (2009) 1.18
Identification on a human sarcoma of two new genes with tumor-specific expression. Cancer Res (2000) 1.17
Expression of immunohistochemical markers for testicular carcinoma in situ by normal human fetal germ cells. Lab Invest (1995) 1.17
From gonocytes to testicular cancer: the role of impaired gonadal development. Ann N Y Acad Sci (2007) 1.08
Population based incidence and age distribution of spermatocytic seminoma. J Urol (2007) 1.07
The POU domain transcription factor POU3F1 is an important intrinsic regulator of GDNF-induced survival and self-renewal of mouse spermatogonial stem cells. Biol Reprod (2010) 1.07
Spermatocytic seminoma. Hum Pathol (1994) 1.06
The immunohistochemical expression pattern of Chk2, p53, p19INK4d, MAGE-A4 and other selected antigens provides new evidence for the premeiotic origin of spermatocytic seminoma. Histopathology (2003) 1.01
Induction of the POU domain transcription factor Oct-2 during T-cell activation by cognate antigen. Mol Cell Biol (1992) 0.93
Reactivity of germ cell maturation stage-specific markers in spermatocytic seminoma: diagnostic and etiological implications. Lab Invest (2001) 0.92
The Oct-2 transcription factor. Int J Biochem Cell Biol (1996) 0.89
The spermatocytic seminoma: views on pathogenesis. Int J Androl (1987) 0.88
Analysis of SOX2 expression in developing human testis and germ cell neoplasia. Int J Dev Biol (2010) 0.88
Spermatogonial stem cells: unlimited potential. Reprod Fertil Dev (2009) 0.83
Transcription factor Oct-2 is expressed in primary murine macrophages. Blood (1996) 0.81
[Ultrastructure and histogenesis of spermatocytic seminoma]. Vopr Onkol (1983) 0.79
Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension. Neuron (2003) 2.89
Handling of radical prostatectomy specimens: total or partial embedding? Histopathology (2011) 2.73
Public health implications of altered puberty timing. Pediatrics (2008) 2.26
ATM activation in normal human tissues and testicular cancer. Cell Cycle (2005) 2.25
Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract. Hum Reprod (2010) 2.00
Next-generation sequencing (NGS) as a diagnostic tool for retinal degeneration reveals a much higher detection rate in early-onset disease. Eur J Hum Genet (2012) 1.80
Gene polymorphisms and male infertility--a meta-analysis and literature review. Reprod Biomed Online (2007) 1.79
Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors. Nat Genet (2009) 1.72
GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia. Blood (2013) 1.60
Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling. Cancer Res (2004) 1.56
Dysregulation of the mitosis-meiosis switch in testicular carcinoma in situ. J Pathol (2013) 1.56
Is human fecundity declining? Int J Androl (2006) 1.52
From embryonic stem cells to testicular germ cell cancer-- should we be concerned? Int J Androl (2006) 1.48
Neural tube defects and associated anomalies in a fetal and perinatal autopsy series. APMIS (2006) 1.45
Phenotypic characterisation of immune cell infiltrates in testicular germ cell neoplasia. J Reprod Immunol (2013) 1.41
Endoscopic ultrasound guided biopsy versus mediastinoscopy for analysis of paratracheal and subcarinal lymph nodes in lung cancer staging. Lung Cancer (2004) 1.40
Adventitious changes in long-range gene expression caused by polymorphic structural variation and promoter competition. Proc Natl Acad Sci U S A (2009) 1.35
Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte. Cancer Res (2009) 1.35
Developmental expression of POU5F1 (OCT-3/4) in normal and dysgenetic human gonads. Hum Reprod (2004) 1.34
Cryptorchidism: classification, prevalence and long-term consequences. Acta Paediatr (2007) 1.31
Increased number of sex chromosomes affects height in a nonlinear fashion: a study of 305 patients with sex chromosome aneuploidy. Am J Med Genet A (2010) 1.31
Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors. Clin Cancer Res (2004) 1.27
The origin of EFNB1 mutations in craniofrontonasal syndrome: frequent somatic mosaicism and explanation of the paucity of carrier males. Am J Hum Genet (2006) 1.22
Meaningful peer review is integral to quality science and should provide benefits to the authors and reviewers alike. Andrology (2013) 1.18
Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasms. Hum Reprod (2008) 1.13
The early human germ cell lineage does not express SOX2 during in vivo development or upon in vitro culture. Biol Reprod (2008) 1.13
Origin of pluripotent germ cell tumours: the role of microenvironment during embryonic development. Mol Cell Endocrinol (2008) 1.11
Increased risk of carcinoma in situ in patients with testicular germ cell cancer with ultrasonic microlithiasis in the contralateral testicle. J Urol (2003) 1.11
Association between testicular dysgenesis syndrome (TDS) and testicular neoplasia: evidence from 20 adult patients with signs of maldevelopment of the testis. APMIS (2003) 1.08
Frequent polymorphism of the mitochondrial DNA polymerase gamma gene (POLG) in patients with normal spermiograms and unexplained subfertility. Hum Reprod (2004) 1.08
Nuclear transit of human zipcode-binding protein IMP1. Biochem J (2003) 1.07
Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours. Virchows Arch (2006) 1.07
Development and descent of the testis in relation to cryptorchidism. Acta Paediatr (2007) 1.06
The changing number of cells in the human fetal forebrain and its subdivisions: a stereological analysis. Cereb Cortex (2003) 1.05
Leydig cell micronodules are a common finding in testicular biopsies from men with impaired spermatogenesis and are associated with decreased testosterone/LH ratio. J Pathol (2003) 1.05
Immunohistochemical demonstration of vascular endothelial growth factor in vestibular schwannomas correlates to tumor growth rate. Laryngoscope (2003) 1.04
Cellular interference in craniofrontonasal syndrome: males mosaic for mutations in the X-linked EFNB1 gene are more severely affected than true hemizygotes. Hum Mol Genet (2013) 1.02
The cancer-testis gene, NY-ESO-1, is expressed in normal fetal and adult testes and in spermatocytic seminomas and testicular carcinoma in situ. Lab Invest (2002) 1.02
Environment, testicular dysgenesis and carcinoma in situ testis. Best Pract Res Clin Endocrinol Metab (2007) 1.00
Natural history of seminiferous tubule degeneration in Klinefelter syndrome. Hum Reprod Update (2005) 1.00
Contributions of intrinsic mutation rate and selfish selection to levels of de novo HRAS mutations in the paternal germline. Proc Natl Acad Sci U S A (2013) 1.00
Deregulation of the G1/S-phase control in human testicular germ cell tumours. APMIS (2003) 0.98
Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers. Mol Cancer (2007) 0.98
Fetal cor triatriatum dexter: a report of two cases associated with nuchal edema in early second trimester. Pediatr Dev Pathol (2008) 0.97
Missing heritability: paternal age effect mutations and selfish spermatogonia. Nat Rev Genet (2010) 0.97
A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation. J Med Genet (2011) 0.96
Spatiotemporal distribution of PAX6 and MEIS2 expression and total cell numbers in the ganglionic eminence in the early developing human forebrain. Dev Neurosci (2010) 0.94
Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer. J Pathol (2003) 0.94
Reduced cell number in the neocortical part of the human fetal brain in Down syndrome. Ann Anat (2008) 0.93
Testicular dysgenesis syndrome and the origin of carcinoma in situ testis. Int J Androl (2008) 0.93
High-resolution comparative genomic hybridization detects extra chromosome arm 12p material in most cases of carcinoma in situ adjacent to overt germ cell tumors, but not before the invasive tumor development. Genes Chromosomes Cancer (2003) 0.91
Deregulation of the RB pathway in human testicular germ cell tumours. J Pathol (2003) 0.90
45,X/46,XY mosaicism: phenotypic characteristics, growth, and reproductive function--a retrospective longitudinal study. J Clin Endocrinol Metab (2012) 0.90
Epigenetic features of testicular germ cell tumours in relation to epigenetic characteristics of foetal germ cells. Int J Dev Biol (2013) 0.90
Testis-specific protein Y-encoded gene is expressed in early and late stages of gonadoblastoma and testicular carcinoma in situ. Urol Oncol (2007) 0.90
No AZF deletion in 160 patients with testicular germ cell neoplasia. Mol Hum Reprod (2003) 0.89
MicroRNA expression profiling of carcinoma in situ cells of the testis. Endocr Relat Cancer (2012) 0.89
Optimizing staining protocols for laser microdissection of specific cell types from the testis including carcinoma in situ. PLoS One (2009) 0.88
Autopsy standards of body parameters and fresh organ weights in nonmacerated and macerated human fetuses. Pediatr Dev Pathol (2005) 0.87
Origin of de novo KCNJ11 mutations and risk of neonatal diabetes for subsequent siblings. J Clin Endocrinol Metab (2007) 0.87
Immunoexpression of androgen receptor and nine markers of maturation in the testes of adolescent boys with Klinefelter syndrome: evidence for degeneration of germ cells at the onset of meiosis. J Clin Endocrinol Metab (2006) 0.87
Analysis of meiosis regulators in human gonads: a sexually dimorphic spatio-temporal expression pattern suggests involvement of DMRT1 in meiotic entry. Mol Hum Reprod (2012) 0.86
Testicular dysgenesis syndrome and Leydig cell function. Basic Clin Pharmacol Toxicol (2008) 0.86
Molecular characteristics of malignant ovarian germ cell tumors and comparison with testicular counterparts: implications for pathogenesis. Endocr Rev (2013) 0.85
Excess of neurons in the human newborn mediodorsal thalamus compared with that of the adult. Cereb Cortex (2007) 0.85
Genome-wide assessment of the association of rare and common copy number variations to testicular germ cell cancer. Front Endocrinol (Lausanne) (2013) 0.85
Fibroblast growth factor receptor 2, gain-of-function mutations, and tumourigenesis: investigating a potential link. J Pathol (2005) 0.85
Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ. Cell Tissue Res (2005) 0.85
Selfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly men. PLoS One (2012) 0.85
Human endocrine gland-derived vascular endothelial growth factor: expression early in development and in Leydig cell tumors suggests roles in normal and pathological testis angiogenesis. J Clin Endocrinol Metab (2004) 0.84
CAG repeat length in androgen-receptor gene and reproductive variables in fertile and infertile men. Lancet (2002) 0.83
UGT2B17 Genotype and the Pharmacokinetic Serum Profile of Testosterone during Substitution Therapy with Testosterone Undecanoate. A Retrospective Experience from 207 Men with Hypogonadism. Front Endocrinol (Lausanne) (2013) 0.83
Recent advances and future directions in research on testicular germ cell cancer. Int J Androl (2007) 0.83
Vitamin D metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo. Neoplasia (2012) 0.83
Open access, scientific integrity and Andrology. Andrology (2013) 0.83
Associations of filaggrin gene loss-of-function variants with urinary phthalate metabolites and testicular function in young Danish Men. Environ Health Perspect (2014) 0.83
Association between polymorphisms in the aryl hydrocarbon receptor repressor gene and disseminated testicular germ cell cancer. Front Endocrinol (Lausanne) (2013) 0.82
Influence of vitamin D on cisplatin sensitivity in testicular germ cell cancer-derived cell lines and in a NTera2 xenograft model. J Steroid Biochem Mol Biol (2012) 0.82
Endoscopic ultrasound guided biopsy performed routinely in lung cancer staging spares futile thoracotomies: preliminary results from a randomised clinical trial. Lung Cancer (2005) 0.82
Accuracy of frozen section diagnosis: a retrospective analysis of 4785 cases. APMIS (2011) 0.82
Current approaches for detection of carcinoma in situ testis. Int J Androl (2007) 0.82
Improved gene expression signature of testicular carcinoma in situ. Int J Androl (2007) 0.82
The 'harsh and the hassle' of science and the slide to irreproducibility: a concern that must be addressed by investigators and journals. Andrology (2013) 0.82
Expression of FGFR3 during human testis development and in germ cell-derived tumours of young adults. Int J Dev Biol (2013) 0.81
Pathogenesis of testicular carcinoma in situ and germ cell cancer: still more questions than answers. Int J Androl (2011) 0.80
Characterization of the testicular, epididymal and endocrine phenotypes in the Leuven Vdr-deficient mouse model: targeting estrogen signalling. Mol Cell Endocrinol (2013) 0.80
Inhibin B: a marker for the functional state of the seminiferous epithelium in patients with azoospermia factor C microdeletions. J Clin Endocrinol Metab (2002) 0.80
Analysis of activin/TGFB-signaling modulators within the normal and dysfunctional adult human testis reveals evidence of altered signaling capacity in a subset of seminomas. Reproduction (2009) 0.80
Correlation between prenatal diagnosis by ultrasound and fetal autopsy findings in second-trimester abortions. Acta Obstet Gynecol Scand (2012) 0.79
Differential developmental expression of transcription factors GATA-4 and GATA-6, their cofactor FOG-2 and downstream target genes in testicular carcinoma in situ and germ cell tumors. Eur J Endocrinol (2009) 0.79
Heterogeneity of chromatin modifications in testicular spermatocytic seminoma point toward an epigenetically unstable phenotype. Cancer Genet (2012) 0.79