Formaldehyde substitute fixatives: effects on nucleic acid preservation.

PubWeight™: 1.02‹?› | Rank: Top 15%

🔗 View Article (PMID 21715573)

Published in J Clin Pathol on June 29, 2011

Authors

Cathy B Moelans1, Daphne Oostenrijk, Michiel J Moons, Paul J van Diest

Author Affiliations

1: Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands. cmoelans@umcutrecht.nl

Articles citing this

Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study. Nat Biotechnol (2014) 1.68

Limitations of widely used high-risk human papillomavirus laboratory-developed testing in cervical cancer screening. Drug Healthc Patient Saf (2012) 0.99

Stability of cervical specimens in SurePath medium for human papillomavirus testing with the Roche cobas 4800 assay. J Clin Microbiol (2013) 0.87

A review of room temperature storage of biospecimen tissue and nucleic acids for anatomic pathology laboratories and biorepositories. Clin Biochem (2013) 0.86

The BD Onclarity HPV Assay on Samples Collected in SurePath Medium Meets the International Guidelines for Human Papillomavirus Test Requirements for Cervical Screening. J Clin Microbiol (2016) 0.82

Evaluation of two commercial and three home-made fixatives for the substitution of formalin: a formaldehyde-free laboratory is possible. Environ Health (2012) 0.79

KINFix - A formalin-free non-commercial fixative optimized for histological, immunohistochemical and molecular analyses of neurosurgical tissue specimens. Clin Neuropathol (2015) 0.79

Whole genome and transcriptome amplification: practicable tools for sustainable tissue biobanking? Virchows Arch (2012) 0.77

Michel's Transport Medium as an Alternative to Liquid Nitrogen for PCR Analysis of Skin Biopsy Specimens. Dermatopathology (Basel) (2014) 0.75

Biobanking in genomic medicine. Arch Pathol Lab Med (2015) 0.75

A Buffered Alcohol-Based Fixative for Histomorphologic and Molecular Applications. J Histochem Cytochem (2016) 0.75

Assessment of alternatives to environmental toxic formalin for DNA conservation in biological specimens. Environ Sci Pollut Res Int (2017) 0.75

Articles by these authors

(truncated to the top 100)

Micrometastases or isolated tumor cells and the outcome of breast cancer. N Engl J Med (2009) 5.36

Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma. Cancer (2003) 3.47

Biologic correlates of (18)fluorodeoxyglucose uptake in human breast cancer measured by positron emission tomography. J Clin Oncol (2002) 2.56

Fallopian tube intraluminal tumor spread from noninvasive precursor lesions: a novel metastatic route in early pelvic carcinogenesis. Am J Surg Pathol (2013) 2.19

Cytogenetic alterations and cytokeratin expression patterns in breast cancer: integrating a new model of breast differentiation into cytogenetic pathways of breast carcinogenesis. Lab Invest (2002) 2.06

Brief fixation does not affect assessment of hormone receptor expression in invasive breast carcinoma biopsies: paving the road for same-day tissue diagnostics. Am J Surg Pathol (2014) 1.95

Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene. Neoplasia (2004) 1.92

Receptor conversion in distant breast cancer metastases. Breast Cancer Res (2010) 1.85

HER-2/neu amplification testing in breast cancer by multiplex ligation-dependent probe amplification in comparison with immunohistochemistry and in situ hybridization. Cell Oncol (2009) 1.70

Going fully digital: Perspective of a Dutch academic pathology lab. J Pathol Inform (2013) 1.67

Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment. Clin Cancer Res (2011) 1.64

Serum CA-125 in relation to adnexal dysplasia and cancer in women at hereditary high risk of ovarian cancer. J Clin Oncol (2007) 1.58

The sentinel node in cervical cancer: scintigraphy and laparoscopic gamma probe-guided biopsy. Eur J Nucl Med Mol Imaging (2004) 1.56

The origin of vimentin expression in invasive breast cancer: epithelial-mesenchymal transition, myoepithelial histogenesis or histogenesis from progenitor cells with bilinear differentiation potential? J Pathol (2005) 1.56

Safety of avoiding routine use of axillary dissection in early stage breast cancer: a systematic review. Breast Cancer Res Treat (2010) 1.53

Genome-wide-array-based comparative genomic hybridization reveals genetic homogeneity and frequent copy number increases encompassing CCNE1 in fallopian tube carcinoma. Oncogene (2003) 1.52

Creation of a fully digital pathology slide archive by high-volume tissue slide scanning. Hum Pathol (2010) 1.52

Tubal and ovarian pathways to pelvic epithelial cancer: a pathological perspective. Histopathology (2009) 1.51

Breast cancer histopathology image analysis: a review. IEEE Trans Biomed Eng (2014) 1.47

Cultures of ovarian surface epithelium from women with and without a hereditary predisposition to develop female adnexal carcinoma. Gynecol Oncol (2004) 1.45

Sentinel node biopsy for nonpalpable breast tumors requires a preoperative diagnosis of invasive breast cancer. Breast J (2003) 1.44

Automatic nuclei segmentation in H&E stained breast cancer histopathology images. PLoS One (2013) 1.43

Hypoxic regulation of metastasis via hypoxia-inducible factors. Curr Mol Med (2008) 1.41

The 3-layered ductal epithelium in gynecomastia. Am J Surg Pathol (2012) 1.40

Promoter hypermethylation patterns in fallopian tube epithelium of BRCA1 and BRCA2 germ line mutation carriers. Endocr Relat Cancer (2012) 1.40

Confocal 3D DNA cytometry: assessment of required coefficient of variation by computer simulation. Cell Oncol (2004) 1.39

Ischemia/reperfusion accelerates the outgrowth of hepatic micrometastases in a highly standardized murine model. Hepatology (2005) 1.37

The molecular genetics and morphometry-based endometrial intraepithelial neoplasia classification system predicts disease progression in endometrial hyperplasia more accurately than the 1994 World Health Organization classification system. Cancer (2005) 1.36

Rapid visualization of human tumor xenografts through optical imaging with a near-infrared fluorescent anti-epidermal growth factor receptor nanobody. Mol Imaging (2012) 1.33

Frequent promoter hypermethylation of BRCA2, CDH13, MSH6, PAX5, PAX6 and WT1 in ductal carcinoma in situ and invasive breast cancer. J Pathol (2011) 1.32

BRCA1/2-related ovarian cancers are of tubal origin: a hypothesis. Gynecol Oncol (2003) 1.31

c-Jun activation is associated with proliferation and angiogenesis in invasive breast cancer. Hum Pathol (2006) 1.30

COMMD1 disrupts HIF-1alpha/beta dimerization and inhibits human tumor cell invasion. J Clin Invest (2010) 1.28

Pathology of hereditary breast cancer. Cell Oncol (Dordr) (2011) 1.28

Accelerated perinecrotic outgrowth of colorectal liver metastases following radiofrequency ablation is a hypoxia-driven phenomenon. Ann Surg (2009) 1.24

Methylation of the TWIST1 promoter, TWIST1 mRNA levels, and immunohistochemical expression of TWIST1 in breast cancer. Cancer Epidemiol Biomarkers Prev (2008) 1.22

Whole slide images for primary diagnostics in dermatopathology: a feasibility study. J Clin Pathol (2011) 1.21

Determination of amplicon boundaries at 20q13.2 in tissue samples of human gastric adenocarcinomas by high-resolution microarray comparative genomic hybridization. J Pathol (2003) 1.21

Whole slide images for primary diagnostics of gastrointestinal tract pathology: a feasibility study. Hum Pathol (2011) 1.21

Protein expression of B-cell lymphoma gene 6 (BCL-6) in invasive breast cancer is associated with cyclin D1 and hypoxia-inducible factor-1alpha (HIF-1alpha). Oncogene (2003) 1.20

The role of hypoxia inducible factor-1alpha in gynecological cancer. Crit Rev Oncol Hematol (2010) 1.19

Prognostic value of estrogen receptor α and progesterone receptor conversion in distant breast cancer metastases. Cancer (2012) 1.18

Feasibility of 7 Tesla breast magnetic resonance imaging determination of intrinsic sensitivity and high-resolution magnetic resonance imaging, diffusion-weighted imaging, and (1)H-magnetic resonance spectroscopy of breast cancer patients receiving neoadjuvant therapy. Invest Radiol (2011) 1.18

Molecular subtyping of male breast cancer by immunohistochemistry. Mod Pathol (2011) 1.17

High frequency of HIF-1alpha overexpression in BRCA1 related breast cancer. Breast Cancer Res Treat (2007) 1.16

Do we see what we think we see? The complexities of morphological assessment. J Pathol (2009) 1.16

Molecular profiling of invasive breast cancer by multiplex ligation-dependent probe amplification-based copy number analysis of tumor suppressor and oncogenes. Mod Pathol (2010) 1.16

Comparative molecular and histological grading of epithelial dysplasia of the oral cavity and the oropharynx. J Pathol (2003) 1.13

Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance. J Clin Invest (2011) 1.13

Absence of chromosome 17 polysomy in breast cancer: analysis by CEP17 chromogenic in situ hybridization and multiplex ligation-dependent probe amplification. Breast Cancer Res Treat (2009) 1.13

HIF1-alpha overexpression indicates a good prognosis in early stage squamous cell carcinomas of the oral floor. BMC Cancer (2005) 1.12

COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70. PLoS One (2009) 1.11

Ovarian carcinogenesis: an alternative hypothesis. Adv Exp Med Biol (2008) 1.09

Radiofrequency ablation of colorectal liver metastases induces an inflammatory response in distant hepatic metastases but not in local accelerated outgrowth. J Surg Oncol (2010) 1.08

Prospective multicenter validation of the independent prognostic value of the mitotic activity index in lymph node-negative breast cancer patients younger than 55 years. J Clin Oncol (2005) 1.08

Non-sentinel lymph node metastases associated with isolated breast cancer cells in the sentinel node. J Natl Cancer Inst (2008) 1.07

Histopathological characteristics of BRCA1- and BRCA2-associated intraperitoneal cancer: a clinic-based study. Fam Cancer (2003) 1.07

Prognostic factors in adult soft tissue sarcomas of the head and neck: a single-centre experience. Oral Oncol (2006) 1.06

Differential Notch and TGFbeta signaling in primary colorectal tumors and their corresponding metastases. Cell Oncol (2008) 1.06

Expression of hypoxia-inducible factor-1alpha and cell cycle proteins in invasive breast cancer are estrogen receptor related. Breast Cancer Res (2004) 1.06

Oncogene amplification in male breast cancer: analysis by multiplex ligation-dependent probe amplification. Breast Cancer Res Treat (2012) 1.06

Atypical MEN type 2B associated with two germline RET mutations on the same allele not involving codon 918. J Clin Endocrinol Metab (2002) 1.05

Her-2/neu testing and therapy in gastroesophageal adenocarcinoma. Patholog Res Int (2010) 1.05

Molecular markers predict outcome in squamous cell carcinoma of the head and neck after concomitant cisplatin-based chemoradiation. Int J Cancer (2009) 1.04

HIF-1 alpha expression is associated with an atheromatous inflammatory plaque phenotype and upregulated in activated macrophages. Atherosclerosis (2007) 1.04

Gene dosage PCR and fluorescence in situ hybridization reveal low frequency of egfr amplifications despite protein overexpression in invasive breast carcinoma. Lab Invest (2004) 1.03

p300 and p53 levels determine activation of HIF-1 downstream targets in invasive breast cancer. Hum Pathol (2006) 1.02

Low frequency of HER2 amplification and overexpression in early onset gastric cancer. Cell Oncol (Dordr) (2011) 1.02

Tales of how great drugs were brought down by a flawed rationale--letter. Clin Cancer Res (2013) 1.02

Prognostic value of automatically extracted nuclear morphometric features in whole slide images of male breast cancer. Mod Pathol (2012) 1.02

Confocal DNA cytometry: a contour-based segmentation algorithm for automated three-dimensional image segmentation. Cytometry (2002) 1.01

Accuracy of sentinel node biopsy after neoadjuvant chemotherapy in breast cancer patients: a systematic review. Eur J Cancer (2009) 1.01

Nuclear morphometric features in benign breast tissue and risk of subsequent breast cancer. Breast Cancer Res Treat (2006) 1.00

The peptidyl-isomerase Pin1 regulates p27kip1 expression through inhibition of Forkhead box O tumor suppressors. Cancer Res (2008) 1.00

Incomplete thermal ablation stimulates proliferation of residual renal carcinoma cells in a translational murine model. BJU Int (2012) 1.00

Hypoxia and angiogenesis in endometrioid endometrial carcinogenesis. Cell Oncol (2007) 1.00

The invasive front in endometrial carcinoma: higher proliferation and associated derailment of cell cycle regulators. Hum Pathol (2007) 1.00

Phosphorylated p-70S6K predicts tamoxifen resistance in postmenopausal breast cancer patients randomized between adjuvant tamoxifen versus no systemic treatment. Breast Cancer Res (2014) 0.99

Local administration of granulocyte/macrophage colony-stimulating factor increases the number and activation state of dendritic cells in the sentinel lymph node of early-stage melanoma. Cancer Res (2004) 0.98

Perinecrotic hypoxia contributes to ischemia/reperfusion-accelerated outgrowth of colorectal micrometastases. Am J Pathol (2007) 0.98

Whole slide images for primary diagnostics of paediatric pathology specimens: a feasibility study. J Clin Pathol (2012) 0.98

Nuclear Kaiso expression is associated with high grade and triple-negative invasive breast cancer. PLoS One (2012) 0.98

PIK3CA mutations, phosphatase and tensin homolog, human epidermal growth factor receptor 2, and insulin-like growth factor 1 receptor and adjuvant tamoxifen resistance in postmenopausal breast cancer patients. Breast Cancer Res (2014) 0.97

Necrosis related HIF-1alpha expression predicts prognosis in patients with endometrioid endometrial carcinoma. BMC Cancer (2010) 0.97

Nuclear localization of the transcriptional coactivator YAP is associated with invasive lobular breast cancer. Cell Oncol (Dordr) (2013) 0.96

HER-2/neu amplification testing in breast cancer by Multiplex Ligation-dependent Probe Amplification: influence of manual- and laser microdissection. BMC Cancer (2009) 0.96

Regional recurrence in breast cancer patients with sentinel node micrometastases and isolated tumor cells. Ann Surg (2012) 0.96

Whole slide images as a platform for initial diagnostics in histopathology in a medium-sized routine laboratory. J Clin Pathol (2012) 0.96

Molecular imaging with a fluorescent antibody targeting carbonic anhydrase IX can successfully detect hypoxic ductal carcinoma in situ of the breast. Breast Cancer Res Treat (2013) 0.96

A novel method to quantify IRDye800CW fluorescent antibody probes ex vivo in tissue distribution studies. EJNMMI Res (2012) 0.96

Expression and localization of hypoxia proteins in prostate cancer: prognostic implications after radical prostatectomy. Urology (2009) 0.95

Low prevalence of (pre) malignant lesions in the breast and high prevalence in the ovary and Fallopian tube in women at hereditary high risk of breast and ovarian cancer. Int J Cancer (2006) 0.95

Active HIF-1 in the normal human retina. J Histochem Cytochem (2009) 0.95

Evolution of the ablation region after magnetic resonance-guided high-intensity focused ultrasound ablation in a Vx2 tumor model. Invest Radiol (2013) 0.94

Valproic acid causes dose- and time-dependent changes in nuclear structure in prostate cancer cells in vitro and in vivo. Mol Cancer Ther (2009) 0.94

Reduced cilia frequencies in human renal cell carcinomas versus neighboring parenchymal tissue. Cilia (2013) 0.94

Development of 3D chromatin texture analysis using confocal laser scanning microscopy. Cell Oncol (2005) 0.94

Re: Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer. J Natl Cancer Inst (2004) 0.94

Analysis of the progression of fibroepithelial tumours of the breast by PCR-based clonality assay. J Pathol (2002) 0.94

Promoter hypermethylation in male breast cancer: analysis by multiplex ligation-dependent probe amplification. Breast Cancer Res (2012) 0.94