Published in Mol Biol Cell on July 07, 2011
Septins: the fourth component of the cytoskeleton. Nat Rev Mol Cell Biol (2012) 2.77
Subunit-dependent modulation of septin assembly: budding yeast septin Shs1 promotes ring and gauze formation. J Cell Biol (2011) 1.40
The emerging functions of septins in metazoans. EMBO Rep (2011) 1.34
SEPT9 occupies the terminal positions in septin octamers and mediates polymerization-dependent functions in abscission. J Cell Biol (2011) 1.22
Septin functions in organ system physiology and pathology. Biol Chem (2014) 1.10
Spatial guidance of cell asymmetry: septin GTPases show the way. Traffic (2011) 1.10
Septin Form and Function at the Cell Cortex. J Biol Chem (2015) 1.08
Septins promote stress fiber-mediated maturation of focal adhesions and renal epithelial motility. J Cell Biol (2014) 1.07
Novel septin 9 repeat motifs altered in neuralgic amyotrophy bind and bundle microtubules. J Cell Biol (2013) 1.06
Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length. J Cell Sci (2013) 1.04
Cytoskeletal dynamics: a view from the membrane. J Cell Biol (2015) 1.03
Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis. PLoS Genet (2014) 0.97
Mammalian SEPT9 isoforms direct microtubule-dependent arrangements of septin core heteromers. Mol Biol Cell (2012) 0.93
Cytosolic chaperones mediate quality control of higher-order septin assembly in budding yeast. Mol Biol Cell (2015) 0.91
Microtubules support a disk-like septin arrangement at the plasma membrane of mammalian cells. Mol Biol Cell (2011) 0.90
The Carboxy-Terminal Tails of Septins Cdc11 and Shs1 Recruit Myosin-II Binding Factor Bni5 to the Bud Neck in Saccharomyces cerevisiae. Genetics (2015) 0.88
Store-independent modulation of Ca(2+) entry through Orai by Septin 7. Nat Commun (2016) 0.87
Mitotic regulation of SEPT9 protein by cyclin-dependent kinase 1 (Cdk1) and Pin1 protein is important for the completion of cytokinesis. J Biol Chem (2013) 0.87
A Förster Resonance Energy Transfer (FRET)-based System Provides Insight into the Ordered Assembly of Yeast Septin Hetero-octamers. J Biol Chem (2015) 0.85
Uncovering principles that control septin-septin interactions. J Biol Chem (2012) 0.85
Sept6 is required for ciliogenesis in Kupffer's vesicle, the pronephros, and the neural tube during early embryonic development. Mol Cell Biol (2014) 0.84
Distinct septin heteropolymers co-exist during multicellular development in the filamentous fungus Aspergillus nidulans. PLoS One (2014) 0.84
Kinetic partitioning during de novo septin filament assembly creates a critical G1 "window of opportunity" for mutant septin function. Cell Cycle (2016) 0.83
Cell type-specific expression of SEPT3-homology subgroup members controls the subunit number of heteromeric septin complexes. Mol Biol Cell (2014) 0.82
Functional insight into the role of Orc6 in septin complex filament formation in Drosophila. Mol Biol Cell (2014) 0.79
Septin cooperation with tubulin polyglutamylation contributes to cancer cell adaptation to taxanes. Oncotarget (2015) 0.78
Septins guide microtubule protrusions induced by actin-depolymerizing toxins like Clostridium difficile transferase (CDT). Proc Natl Acad Sci U S A (2016) 0.78
Septin 9 interacts with kinesin KIF17 and interferes with the mechanism of NMDA receptor cargo binding and transport. Mol Biol Cell (2016) 0.77
GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis. Sci Rep (2016) 0.77
Partial Functional Diversification of Drosophila melanogaster Septin Genes Sep2 and Sep5. G3 (Bethesda) (2016) 0.77
A FRET-based method for monitoring septin polymerization and binding of septin-associated proteins. Methods Cell Biol (2016) 0.76
Septin Mutations in Human Cancers. Front Cell Dev Biol (2016) 0.75
Preparing recombinant yeast septins and their analysis by electron microscopy. Methods Cell Biol (2016) 0.75
Regulation of Store-Operated Ca(2+) Entry by Septins. Front Cell Dev Biol (2016) 0.75
The requirement of SEPT2 and SEPT7 for migration and invasion in human breast cancer via MEK/ERK activation. Oncotarget (2016) 0.75
Cancer-Related Functions and Subcellular Localizations of Septins. Front Cell Dev Biol (2016) 0.75
Septin 9_i2 is downregulated in tumors, impairs cancer cell migration and alters subnuclear actin filaments. Sci Rep (2017) 0.75
A theoretical model of cytokinesis implicates feedback between membrane curvature and cytoskeletal organization in asymmetric cytokinetic furrowing. Mol Biol Cell (2016) 0.75
The Mammalian Septin Interactome. Front Cell Dev Biol (2017) 0.75
The Borg family of Cdc42 effector proteins Cdc42EP1-5. Biochem Soc Trans (2016) 0.75
Effects of Bni5 Binding on Septin Filament Organization. J Mol Biol (2016) 0.75
Functional Redundancy of Septin Homologs in Dendritic Branching. Front Cell Dev Biol (2017) 0.75
Structural and Thermodynamic Properties of Septin 3 Investigated by Small-Angle X-Ray Scattering. Biophys J (2015) 0.75
Colorectal cancer screening: An updated review of the available options. World J Gastroenterol (2017) 0.75
Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases. Biochim Biophys Acta (1966) 16.27
Self- and actin-templated assembly of Mammalian septins. Dev Cell (2002) 4.48
A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution. Science (2010) 4.11
Structural insight into filament formation by mammalian septins. Nature (2007) 2.90
Planar cell polarity acts through septins to control collective cell movement and ciliogenesis. Science (2010) 2.89
A purified Drosophila septin complex forms filaments and exhibits GTPase activity. J Cell Biol (1996) 2.76
Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly. Proc Natl Acad Sci U S A (2008) 2.46
Septins and the lateral compartmentalization of eukaryotic membranes. Dev Cell (2009) 2.44
The septin family of GTPases: architecture and dynamics. Nat Rev Mol Cell Biol (2008) 2.38
GTP binding induces filament assembly of a recombinant septin. Curr Biol (2002) 2.16
Oncoprotein 18 is a phosphorylation-responsive regulator of microtubule dynamics. EMBO J (1996) 2.15
Analysis of septins across kingdoms reveals orthology and new motifs. BMC Evol Biol (2007) 2.04
Septin structure and function in yeast and beyond. Trends Cell Biol (2010) 1.99
Amoeboid T lymphocytes require the septin cytoskeleton for cortical integrity and persistent motility. Nat Cell Biol (2008) 1.88
Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4. Mol Biol Cell (2005) 1.75
The Caenorhabditis elegans septin complex is nonpolar. EMBO J (2007) 1.69
Borg/septin interactions and the assembly of mammalian septin heterodimers, trimers, and filaments. J Biol Chem (2002) 1.69
Expression profiling the human septin gene family. J Pathol (2005) 1.67
Assembly of mammalian septins. J Biochem (2003) 1.64
The septins. Genome Biol (2003) 1.58
Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission. J Cell Biol (2010) 1.55
Regulation of microtubule dynamics by extracellular signals: cAMP-dependent protein kinase switches off the activity of oncoprotein 18 in intact cells. J Cell Biol (1998) 1.36
GTP-induced conformational changes in septins and implications for function. Proc Natl Acad Sci U S A (2009) 1.35
Conquering the complex world of human septins: implications for health and disease. Clin Genet (2010) 1.29
Structural analysis of septin 2, 6, and 7 complexes. J Biol Chem (2006) 1.08
Phylogenetic and evolutionary analysis of the septin protein family in metazoan. FEBS Lett (2007) 1.08
GTP binding and hydrolysis kinetics of human septin 2. FEBS J (2006) 1.04
3D reconstruction of mammalian septin filaments. J Mol Biol (2007) 1.02
The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 assembles into a nine-subunit oligomer with potential To inhibit Toll-like receptor signaling. Infect Immun (2009) 1.02
Global regulation of the interphase microtubule system by abundantly expressed Op18/stathmin. Mol Biol Cell (2008) 0.95
Interphase-specific phosphorylation-mediated regulation of tubulin dimer partitioning in human cells. Mol Biol Cell (2007) 0.95
Deciphering the cellular functions of the Op18/Stathmin family of microtubule-regulators by plasma membrane-targeted localization. Mol Biol Cell (2003) 0.87
Reconstitution of a microtubule plus-end tracking system in vitro. Nature (2007) 3.50
Differential functional interplay of TOGp/XMAP215 and the KinI kinesin MCAK during interphase and mitosis. EMBO J (2004) 1.55
MAP4 counteracts microtubule catastrophe promotion but not tubulin-sequestering activity in intact cells. Curr Biol (2002) 1.09
The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 assembles into a nine-subunit oligomer with potential To inhibit Toll-like receptor signaling. Infect Immun (2009) 1.02
CaMKIIgamma-mediated inactivation of the Kin I kinesin MCAK is essential for bipolar spindle formation. EMBO J (2005) 0.99
The evolutionarily conserved single-copy gene for murine Tpr encodes one prevalent isoform in somatic cells and lacks paralogs in higher eukaryotes. Chromosoma (2002) 0.97
Dynamic gradients of an intermediate filament-like cytoskeleton are recruited by a polarity landmark during apical growth. Proc Natl Acad Sci U S A (2013) 0.96
Interphase-specific phosphorylation-mediated regulation of tubulin dimer partitioning in human cells. Mol Biol Cell (2007) 0.95
Global regulation of the interphase microtubule system by abundantly expressed Op18/stathmin. Mol Biol Cell (2008) 0.95
Predominant regulators of tubulin monomer-polymer partitioning and their implication for cell polarization. Cell Mol Life Sci (2009) 0.93
Mammalian SEPT9 isoforms direct microtubule-dependent arrangements of septin core heteromers. Mol Biol Cell (2012) 0.93
Tubulin dimers oligomerize before their incorporation into microtubules. PLoS One (2008) 0.93
Interphase and monoastral-mitotic phenotypes of overexpressed MAP4 are modulated by free tubulin concentrations. J Cell Sci (2003) 0.91
Autonomous and phosphorylation-responsive microtubule-regulating activities of the N-terminus of Op18/stathmin. J Cell Sci (2003) 0.90
Microtubules support a disk-like septin arrangement at the plasma membrane of mammalian cells. Mol Biol Cell (2011) 0.90
Aneugenic activity of Op18/stathmin is potentiated by the somatic Q18-->e mutation in leukemic cells. Mol Biol Cell (2006) 0.89
Electron tomography reveals a flared morphology on growing microtubule ends. J Cell Sci (2011) 0.88
The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 is a membrane-binding protein that lacks the proposed microtubule-regulatory activity. Mol Biochem Parasitol (2007) 0.87
Deciphering the cellular functions of the Op18/Stathmin family of microtubule-regulators by plasma membrane-targeted localization. Mol Biol Cell (2003) 0.87
Op18/Stathmin counteracts the activity of overexpressed tubulin-disrupting proteins in a human leukemia cell line. Exp Cell Res (2008) 0.85
The N-terminal region of amyloid β controls the aggregation rate and fibril stability at low pH through a gain of function mechanism. J Am Chem Soc (2014) 0.85
Upregulated Op18/stathmin activity causes chromosomal instability through a mechanism that evades the spindle assembly checkpoint. Exp Cell Res (2010) 0.80
Molecular dissection of GTP exchange and hydrolysis within the ternary complex of tubulin heterodimers and Op18/stathmin family members. J Biol Chem (2003) 0.79
Non-sporulating ftsZ mutants in Streptomyces coelicolor reveal amino acid residues critical for FtsZ polymerization dynamics. Microbiology (2013) 0.75