Published in Nat Cell Biol on November 30, 2008
Planar cell polarity acts through septins to control collective cell movement and ciliogenesis. Science (2010) 2.89
Septins: the fourth component of the cytoskeleton. Nat Rev Mol Cell Biol (2012) 2.77
Breaching multiple barriers: leukocyte motility through venular walls and the interstitium. Nat Rev Mol Cell Biol (2010) 2.72
Significantly improved precision of cell migration analysis in time-lapse video microscopy through use of a fully automated tracking system. BMC Cell Biol (2010) 2.04
Septin assemblies form by diffusion-driven annealing on membranes. Proc Natl Acad Sci U S A (2014) 1.89
Bringing up the rear: defining the roles of the uropod. Nat Rev Mol Cell Biol (2009) 1.74
Use the force: membrane tension as an organizer of cell shape and motility. Trends Cell Biol (2012) 1.56
Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission. J Cell Biol (2010) 1.55
Microtubules regulate migratory polarity through Rho/ROCK signaling in T cells. PLoS One (2010) 1.49
Integrin function in T-cell homing to lymphoid and nonlymphoid sites: getting there and staying there. Crit Rev Immunol (2009) 1.49
Septin filaments exhibit a dynamic, paired organization that is conserved from yeast to mammals. J Cell Biol (2011) 1.41
Deciphering the rules governing assembly order of mammalian septin complexes. Mol Biol Cell (2011) 1.35
The emerging functions of septins in metazoans. EMBO Rep (2011) 1.34
Control of cortical rigidity by the cytoskeleton: emerging roles for septins. Cytoskeleton (Hoboken) (2010) 1.24
The multiple faces of leukocyte interstitial migration. Semin Immunopathol (2014) 1.12
The septin cytoskeleton facilitates membrane retraction during motility and blebbing. J Cell Biol (2012) 1.11
Septin functions in organ system physiology and pathology. Biol Chem (2014) 1.10
Spatial guidance of cell asymmetry: septin GTPases show the way. Traffic (2011) 1.10
Septin Form and Function at the Cell Cortex. J Biol Chem (2015) 1.08
Septins promote stress fiber-mediated maturation of focal adhesions and renal epithelial motility. J Cell Biol (2014) 1.07
Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton. J Cell Biol (2016) 1.07
Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length. J Cell Sci (2013) 1.04
Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis. PLoS Genet (2014) 0.97
Tumor treating fields perturb the localization of septins and cause aberrant mitotic exit. PLoS One (2015) 0.94
Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation. Nat Commun (2013) 0.94
Microtubules support a disk-like septin arrangement at the plasma membrane of mammalian cells. Mol Biol Cell (2011) 0.90
The Carboxy-Terminal Tails of Septins Cdc11 and Shs1 Recruit Myosin-II Binding Factor Bni5 to the Bud Neck in Saccharomyces cerevisiae. Genetics (2015) 0.88
Uncovering principles that control septin-septin interactions. J Biol Chem (2012) 0.85
Distinct septin heteropolymers co-exist during multicellular development in the filamentous fungus Aspergillus nidulans. PLoS One (2014) 0.84
Dynamics of dendritic cell-T cell interactions: a role in T cell outcome. Semin Immunopathol (2010) 0.84
Septin dynamics are essential for exocytosis. J Biol Chem (2015) 0.82
Uncovering the Roles of Septins in Cilia. Front Cell Dev Biol (2017) 0.82
A septin requirement differentiates autonomous and contact-facilitated T cell proliferation. Nat Immunol (2015) 0.81
NSOM/QD-based fluorescence-topographic image fusion directly reveals nano-spatial peak-valley polarities of CD69 and CD71 activation molecules on cell-membrane fluctuations during T-cell activation. Immunol Lett (2011) 0.81
Rho1- and Pkc1-dependent phosphorylation of the F-BAR protein Syp1 contributes to septin ring assembly. Mol Biol Cell (2015) 0.81
Actomyosin Cortical Mechanical Properties in Nonadherent Cells Determined by Atomic Force Microscopy. Biophys J (2016) 0.80
Unraveling the equine lymphocyte proteome: differential septin 7 expression associates with immune cells in equine recurrent uveitis. PLoS One (2014) 0.80
An Overview of Alternating Electric Fields Therapy (NovoTTF Therapy) for the Treatment of Malignant Glioma. Curr Neurol Neurosci Rep (2016) 0.78
Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins. Int J Parasitol (2014) 0.78
Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts. Small GTPases (2016) 0.77
Physical view on migration modes. Cell Adh Migr (2015) 0.77
Partial Functional Diversification of Drosophila melanogaster Septin Genes Sep2 and Sep5. G3 (Bethesda) (2016) 0.77
The planar cell polarity effector protein Wdpcp (Fritz) controls epithelial cell cortex dynamics via septins and actomyosin. Biochem Biophys Res Commun (2014) 0.76
Undressing a cellular corset: septins exposed. Nat Cell Biol (2009) 0.76
Quantitative characterization of cell behaviors through cell cycle progression via automated cell tracking. PLoS One (2014) 0.76
Matthew Krummel: visions enumerated. Interview by Amy Maxmen. J Exp Med (2009) 0.75
Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction. Elife (2016) 0.75
Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion. Exp Cell Res (2016) 0.75
In vivo TCR Signaling in CD4(+) T Cells Imprints a Cell-Intrinsic, Transient Low-Motility Pattern Independent of Chemokine Receptor Expression Levels, or Microtubular Network, Integrin, and Protein Kinase C Activity. Front Immunol (2015) 0.75
Cancer-Related Functions and Subcellular Localizations of Septins. Front Cell Dev Biol (2016) 0.75
Proteomics identifies differentially expressed proteins in neonatal murine thymus compared with adults. Proteome Sci (2012) 0.75
Editorial: Emerging Functions of Septins. Front Cell Dev Biol (2017) 0.75
Two distinct actin networks drive the protrusion of migrating cells. Science (2004) 7.69
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell (2003) 6.46
Genetic analysis of the mitotic transmission of minichromosomes. Cell (1985) 5.45
Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier. Science (2000) 4.95
Self- and actin-templated assembly of Mammalian septins. Dev Cell (2002) 4.48
Non-equilibration of hydrostatic pressure in blebbing cells. Nature (2005) 4.08
Chemotaxis in shallow gradients is mediated independently of PtdIns 3-kinase by biased choices between random protrusions. Nat Cell Biol (2007) 3.52
Compartmentalization of the cell cortex by septins is required for maintenance of cell polarity in yeast. Mol Cell (2000) 3.23
Leukocyte polarization in cell migration and immune interactions. EMBO J (1999) 3.08
N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility. Nat Cell Biol (2001) 2.91
Structural insight into filament formation by mammalian septins. Nature (2007) 2.90
Phosphorylation-dependent regulation of septin dynamics during the cell cycle. Dev Cell (2003) 2.65
Role of Septin cytoskeleton in spine morphogenesis and dendrite development in neurons. Curr Biol (2007) 2.60
The role of Cdc42p GTPase-activating proteins in assembly of the septin ring in yeast. Mol Biol Cell (2003) 2.57
A mitotic septin scaffold required for Mammalian chromosome congression and segregation. Science (2005) 2.37
G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motility. J Cell Biol (2007) 2.34
The mammalian septin MSF localizes with microtubules and is required for completion of cytokinesis. Mol Biol Cell (2002) 2.25
The pathobiology of the septin gene family. J Pathol (2004) 2.24
Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa. Dev Cell (2005) 2.21
A single class II myosin modulates T cell motility and stopping, but not synapse formation. Nat Immunol (2004) 2.20
WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility. EMBO J (2003) 1.98
Some assembly required: yeast septins provide the instruction manual. Trends Cell Biol (2005) 1.96
Actin and septin ultrastructures at the budding yeast cell cortex. Mol Biol Cell (2004) 1.94
Filament formation of MSF-A, a mammalian septin, in human mammary epithelial cells depends on interactions with microtubules. J Biol Chem (2003) 1.82
Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4. Mol Biol Cell (2005) 1.75
Diversity of septin scaffolds. Curr Opin Cell Biol (2005) 1.69
Expression profiling the human septin gene family. J Pathol (2005) 1.67
MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25). Proc Natl Acad Sci U S A (1999) 1.60
WASP deficiency leads to global defects of directed leukocyte migration in vitro and in vivo. J Leukoc Biol (2005) 1.59
The Septin 9 (MSF) gene is amplified and overexpressed in mouse mammary gland adenocarcinomas and human breast cancer cell lines. Cancer Res (2003) 1.56
Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11. J Biol Chem (2004) 1.54
Characterization of anillin mutants reveals essential roles in septin localization and plasma membrane integrity. Development (2005) 1.37
A prototypic platelet septin and its participation in secretion. Proc Natl Acad Sci U S A (2002) 1.36
Microtubule retraction into the uropod and its role in T cell polarization and motility. J Immunol (1997) 1.26
Do septins have a role in cancer? Br J Cancer (2005) 1.20
Lymphocyte HEV adhesion variants differ in the expression of multiple gene sequences. Gene (1990) 1.19
Sint1, a common integration site in SL3-3-induced T-cell lymphomas, harbors a putative proto-oncogene with homology to the septin gene family. J Virol (2000) 1.03
T cell synapse assembly: proteins, motors and the underlying cell biology. Semin Immunol (2005) 0.86
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol (2005) 7.44
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat Immunol (2009) 5.20
Deletional tolerance mediated by extrathymic Aire-expressing cells. Science (2008) 4.10
Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol (2005) 4.01
Entrapment of intracytosolic bacteria by septin cage-like structures. Cell Host Microbe (2010) 3.39
Type 2 innate lymphoid cells control eosinophil homeostasis. Nature (2013) 3.20
Stabilized imaging of immune surveillance in the mouse lung. Nat Methods (2010) 2.66
Role of Septin cytoskeleton in spine morphogenesis and dendrite development in neurons. Curr Biol (2007) 2.60
Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function. Cell (2011) 2.57
A mitotic septin scaffold required for Mammalian chromosome congression and segregation. Science (2005) 2.37
Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy. Dis Model Mech (2008) 2.34
The mammalian septin MSF localizes with microtubules and is required for completion of cytokinesis. Mol Biol Cell (2002) 2.25
Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa. Dev Cell (2005) 2.21
A single class II myosin modulates T cell motility and stopping, but not synapse formation. Nat Immunol (2004) 2.20
Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity. Neuron (2007) 2.08
Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Mol Cell Biol (2003) 2.03
Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation to T cells in the lung. J Exp Med (2012) 2.03
Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells. Cancer Cell (2012) 1.95
Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb. J Biol Chem (2007) 1.89
Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions. Nat Immunol (2010) 1.82
Dynamics of p56lck translocation to the T cell immunological synapse following agonist and antagonist stimulation. Immunity (2002) 1.77
Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella. Nat Cell Biol (2002) 1.75
Diagnostic criteria for dyslipidemia. Executive summary of Japan Atherosclerosis Society (JAS) guideline for diagnosis and prevention of atherosclerotic cardiovascular diseases for Japanese. J Atheroscler Thromb (2007) 1.70
Epithelial polarity requires septin coupling of vesicle transport to polyglutamylated microtubules. J Cell Biol (2008) 1.65
Myosin-IIA and ICAM-1 regulate the interchange between two distinct modes of T cell migration. J Immunol (2009) 1.63
Perivascular mast cells dynamically probe cutaneous blood vessels to capture immunoglobulin E. Immunity (2013) 1.62
Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission. J Cell Biol (2010) 1.55
Surface-bound chemokines capture and prime T cells for synapse formation. Nat Immunol (2006) 1.53
A synaptic basis for paracrine interleukin-2 signaling during homotypic T cell interaction. Immunity (2008) 1.52
Imaging synapse formation during thymocyte selection: inability of CD3zeta to form a stable central accumulation during negative selection. Immunity (2002) 1.51
Mammalian SEPT2 is required for scaffolding nonmuscle myosin II and its kinases. Dev Cell (2007) 1.50
Impact of early surgery in the active phase on long-term outcomes in left-sided native valve infective endocarditis. J Thorac Cardiovasc Surg (2011) 1.48
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Clinical outcomes of medical therapy and timely operation in initially diagnosed type a aortic intramural hematoma: a 20-year experience. Circulation (2009) 1.43
Intramuscular transplantation of G-CSF-mobilized CD34(+) cells in patients with critical limb ischemia: a phase I/IIa, multicenter, single-blinded, dose-escalation clinical trial. Stem Cells (2009) 1.43
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Mapping the cellular response to small molecules using chemogenomic fitness signatures. Science (2014) 1.39
Successful thrombus aspiration during primary percutaneous coronary intervention reduces infarct size and preserves myocardial viability: a cardiac magnetic resonance imaging study. J Invasive Cardiol (2011) 1.39
Real-time analysis of T cell receptors in naive cells in vitro and in vivo reveals flexibility in synapse and signaling dynamics. J Exp Med (2010) 1.38
Syntaxin 5 is required for cytokinesis and spermatid differentiation in Drosophila. Dev Biol (2002) 1.37
A prototypic platelet septin and its participation in secretion. Proc Natl Acad Sci U S A (2002) 1.36
Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ialpha impairs localized actin remodeling and suppresses phagocytosis. J Biol Chem (2002) 1.35
Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. Nature (2013) 1.30
Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect. Blood (2004) 1.27
Annular geometry in patients with chronic ischemic mitral regurgitation: three-dimensional magnetic resonance imaging study. Circulation (2005) 1.25
Control of cortical rigidity by the cytoskeleton: emerging roles for septins. Cytoskeleton (Hoboken) (2010) 1.24
Integration of the movement of signaling microclusters with cellular motility in immunological synapses. Nat Immunol (2012) 1.23
Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proc Natl Acad Sci U S A (2013) 1.23
SEPT9 occupies the terminal positions in septin octamers and mediates polymerization-dependent functions in abscission. J Cell Biol (2011) 1.22
Septins regulate developmental switching from microdomain to nanodomain coupling of Ca(2+) influx to neurotransmitter release at a central synapse. Neuron (2010) 1.22
Two-photon imaging of the immune system: a custom technology platform for high-speed, multicolor tissue imaging of immune responses. Curr Top Microbiol Immunol (2009) 1.19
The septin CDCrel-1 is dispensable for normal development and neurotransmitter release. Mol Cell Biol (2002) 1.19
Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies. J Biol Chem (2003) 1.19
Abnormalities of SNARE mechanism proteins in anterior frontal cortex in severe mental illness. Cereb Cortex (2002) 1.18
Amplification of autoimmune response through induction of dendritic cell maturation in inflamed tissues. J Immunol (2009) 1.18
Structural insights shed light onto septin assemblies and function. Curr Opin Cell Biol (2008) 1.17
Rho and anillin-dependent control of mDia2 localization and function in cytokinesis. Mol Biol Cell (2010) 1.17
Mammalian septins nomenclature. Mol Biol Cell (2002) 1.16
Mammalian septins are required for phagosome formation. Mol Biol Cell (2008) 1.16
Regulation of T cell priming by lymphoid stroma. PLoS One (2011) 1.14
Secondary T cell-T cell synaptic interactions drive the differentiation of protective CD8+ T cells. Nat Immunol (2013) 1.14
Syntaxins 13 and 7 function at distinct steps during phagocytosis. J Immunol (2002) 1.13
Quantifying signaling-induced reorientation of T cell receptors during immunological synapse formation. Proc Natl Acad Sci U S A (2002) 1.13
Coronin-1 function is required for phagosome formation. Mol Biol Cell (2005) 1.12
Stabilization of the actomyosin ring enables spermatocyte cytokinesis in Drosophila. Mol Biol Cell (2010) 1.11
The septin cytoskeleton facilitates membrane retraction during motility and blebbing. J Cell Biol (2012) 1.11
Septins. Curr Biol (2011) 1.10
Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naive T cells. J Immunol (2012) 1.10
Sept12 is a component of the mammalian sperm tail annulus. Cell Motil Cytoskeleton (2007) 1.10
Septins as diagnostic markers for a subset of human asthenozoospermia. J Urol (2008) 1.09
Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates myocardial ischemia/reperfusion injury in a rat model. Lab Invest (2003) 1.09
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New views of the immunological synapse: variations in assembly and function. Curr Opin Immunol (2004) 1.08
Disruption of Sept6, a fusion partner gene of MLL, does not affect ontogeny, leukemogenesis induced by MLL-SEPT6, or phenotype induced by the loss of Sept4. Mol Cell Biol (2005) 1.07
Metabolic syndrome. J Atheroscler Thromb (2008) 1.06
CD28 signals in the immature immunological synapse. J Immunol (2004) 1.06
Phosphatidic acid (PA)-preferring phospholipase A1 regulates mitochondrial dynamics. J Biol Chem (2014) 1.05
The septin Sept5/CDCrel-1 competes with alpha-SNAP for binding to the SNARE complex. Biochem J (2005) 1.05
Duration of antigen receptor signaling determines T-cell tolerance or activation. Proc Natl Acad Sci U S A (2010) 1.05
Retracted Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice. J Clin Invest (2010) 1.05
Characterization of a SEPT9 interacting protein, SEPT14, a novel testis-specific septin. Mamm Genome (2007) 1.04
Imaging the function of regulatory T cells in vivo. Curr Opin Immunol (2006) 1.04
GTP binding and hydrolysis kinetics of human septin 2. FEBS J (2006) 1.04
Uptake of oxidized low density lipoprotein by CD36 occurs by an actin-dependent pathway distinct from macropinocytosis. J Biol Chem (2009) 1.04
Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization. Dev Cell (2013) 1.04
Plasmalogens in human serum positively correlate with high- density lipoprotein and decrease with aging. J Atheroscler Thromb (2007) 1.03
Septin 3 (G-septin) is a developmentally regulated phosphoprotein enriched in presynaptic nerve terminals. J Neurochem (2004) 1.03
The structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of an inhibitor family. Structure (2007) 1.03
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication. Infect Immun (2008) 1.02
Proline-rich tyrosine kinase 2 and Rac activation by chemokine and integrin receptors controls NK cell transendothelial migration. J Immunol (2003) 1.02
Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice. Hum Mol Genet (2009) 1.01
Mediation of T-cell activation by actin meshworks. Cold Spring Harb Perspect Biol (2010) 1.00
Septins: traffic control at the cytokinesis intersection. Traffic (2005) 1.00