Published in Hum Mol Genet on July 08, 2011
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. Nat Genet (2014) 2.72
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. Am J Hum Genet (2013) 2.24
ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens. Genome Res (2012) 1.86
Comprehensive functional annotation of 77 prostate cancer risk loci. PLoS Genet (2014) 1.48
A genome-wide pleiotropy scan for prostate cancer risk. Eur Urol (2014) 1.48
A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. Hum Mol Genet (2012) 1.47
Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma. Nat Genet (2014) 1.41
An analysis of the association between prostate cancer risk loci, PSA levels, disease aggressiveness and disease-specific mortality. Br J Cancer (2015) 1.39
The genetic epidemiology of prostate cancer and its clinical implications. Nat Rev Urol (2013) 1.39
Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus. Genome Res (2012) 1.35
Genome-wide association study identifies multiple loci associated with bladder cancer risk. Hum Mol Genet (2013) 1.34
Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33. Hum Mol Genet (2014) 1.09
Evaluating genetic risk for prostate cancer among Japanese and Latinos. Cancer Epidemiol Biomarkers Prev (2012) 1.08
Two susceptibility loci identified for prostate cancer aggressiveness. Nat Commun (2015) 1.06
Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium. Am J Epidemiol (2012) 1.05
Genetic variation in the vitamin d pathway in relation to risk of prostate cancer--results from the breast and prostate cancer cohort consortium. Cancer Epidemiol Biomarkers Prev (2013) 1.03
Re-ranking sequencing variants in the post-GWAS era for accurate causal variant identification. PLoS Genet (2013) 1.00
The role of BRCA1 and BRCA2 in prostate cancer. Asian J Androl (2012) 1.00
Prostate cancer risk-associated genetic markers and their potential clinical utility. Asian J Androl (2013) 0.97
A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. Cancer Discov (2015) 0.97
Generalizability of established prostate cancer risk variants in men of African ancestry. Int J Cancer (2014) 0.96
Plateau effect of prostate cancer risk-associated SNPs in discriminating prostate biopsy outcomes. Prostate (2013) 0.96
Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk. Proc Natl Acad Sci U S A (2012) 0.91
Genetics and genomics of prostate cancer. Asian J Androl (2013) 0.90
Genetic variation in prostate-specific antigen-detected prostate cancer and the effect of control selection on genetic association studies. Cancer Epidemiol Biomarkers Prev (2014) 0.89
The genomic landscape of prostate cancer. Int J Mol Sci (2013) 0.88
Variants at IRX4 as prostate cancer expression quantitative trait loci. Eur J Hum Genet (2013) 0.87
CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants. Nat Med (2015) 0.87
A scalable and portable framework for massively parallel variable selection in genetic association studies. Bioinformatics (2012) 0.86
Common genetic variation of the calcium-sensing receptor and lethal prostate cancer risk. Cancer Epidemiol Biomarkers Prev (2012) 0.86
Gene variants in the angiogenesis pathway and prostate cancer. Carcinogenesis (2012) 0.85
Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions. Hum Mol Genet (2015) 0.85
The prostate cancer susceptibility variant rs2735839 near KLK3 gene is associated with aggressive prostate cancer and can stratify gleason score 7 patients. Clin Cancer Res (2014) 0.84
One thousand genomes imputation in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium aggressive prostate cancer genome-wide association study. Prostate (2012) 0.83
The role of single nucleotide polymorphisms in predicting prostate cancer risk and therapeutic decision making. Biomed Res Int (2014) 0.83
An expressed retrogene of the master embryonic stem cell gene POU5F1 is associated with prostate cancer susceptibility. Am J Hum Genet (2014) 0.82
Genetic susceptibility loci, pesticide exposure and prostate cancer risk. PLoS One (2013) 0.82
Genome-wide association scan for variants associated with early-onset prostate cancer. PLoS One (2014) 0.82
Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions. Hum Mol Genet (2015) 0.81
Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk. Hum Mol Genet (2015) 0.81
Fine-mapping of IL16 gene and prostate cancer risk in African Americans. Cancer Epidemiol Biomarkers Prev (2012) 0.81
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nat Commun (2016) 0.81
Synonymous Polymorphisms in HOXB13 as a Protective Factor for Prostate Cancer. J Cancer (2015) 0.80
Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk. PLoS Genet (2017) 0.79
Reclassification of genetic-based risk predictions as GWAS data accumulate. Genome Med (2016) 0.79
Functional annotation of putative regulatory elements at cancer susceptibility Loci. Cancer Inform (2014) 0.79
Validation of association of genetic variants at 10q with prostate-specific antigen (PSA) levels in men at high risk for prostate cancer. BJU Int (2013) 0.79
Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry. Hum Genet (2012) 0.79
Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis. PLoS One (2014) 0.79
Genome-wide association studies on prostate cancer: the end or the beginning? Protein Cell (2013) 0.79
Circadian clock genes and risk of fatal prostate cancer. Cancer Causes Control (2014) 0.79
A comprehensive resequence-analysis of 250 kb region of 8q24.21 in men of African ancestry. Prostate (2014) 0.78
Genome-wide association study identifies possible genetic risk factors for colorectal adenomas. Cancer Epidemiol Biomarkers Prev (2013) 0.78
A genetic study and meta-analysis of the genetic predisposition of prostate cancer in a Chinese population. Oncotarget (2016) 0.78
Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis. BJU Int (2012) 0.77
Analysis of Prostate Cancer Susceptibility Variants in South African Men: Replicating Associations on Chromosomes 8q24 and 10q11. Prostate Cancer (2015) 0.77
The use of exome genotyping to predict pathological Gleason score upgrade after radical prostatectomy in low-risk prostate cancer patients. PLoS One (2014) 0.77
Folate intake, alcohol consumption, and the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism: influence on prostate cancer risk and interactions. Front Oncol (2012) 0.76
Prostate Cancer Genetics: A Review. EJIFCC (2015) 0.75
PharmGKB summary: very important pharmacogene information for SLC22A1. Pharmacogenet Genomics (2014) 0.75
HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer. Oncotarget (2016) 0.75
Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21. Hum Genet (2016) 0.75
A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts. PLoS One (2017) 0.75
Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits. Genome Med (2017) 0.75
Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. PLoS One (2017) 0.75
Utility of single nucleotide polymorphisms in prostate biopsy decisions. Rev Urol (2012) 0.75
Assessing the Cumulative Contribution of New and Established Common Genetic Risk Factors to Early-Onset Prostate Cancer. Cancer Epidemiol Biomarkers Prev (2015) 0.75
Germline genetic profiling in prostate cancer: latest developments and potential clinical applications. Future Sci OA (2015) 0.75
ABO blood group alleles and prostate cancer risk: Results from the breast and prostate cancer cohort consortium (BPC3). Prostate (2015) 0.75
Use of a Novel Nonparametric Version of DEPTH to Identify Genomic Regions Associated with Prostate Cancer Risk. Cancer Epidemiol Biomarkers Prev (2016) 0.75
Putative Prostate Cancer Risk SNP in an Androgen Receptor-Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites. Hum Mutat (2015) 0.75
Incorporating Known Genetic Variants Does Not Improve the Accuracy of PSA Testing to Identify High Risk Prostate Cancer on Biopsy. PLoS One (2015) 0.75
Heritability of prostate cancer: a tale of rare variants and common single nucleotide polymorphisms. Ann Transl Med (2016) 0.75
Identification of candidate protective variants for common diseases and evaluation of their protective potential. BMC Genomics (2017) 0.75
Prospective study of DNA methylation at chromosome 8q24 in peripheral blood and prostate cancer risk. Br J Cancer (2017) 0.75
Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer. PLoS Genet (2017) 0.75
Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med (2000) 25.49
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet (2007) 19.18
Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65
Radical prostatectomy versus watchful waiting in early prostate cancer. N Engl J Med (2005) 16.35
Multiple newly identified loci associated with prostate cancer susceptibility. Nat Genet (2008) 15.43
A common variant associated with prostate cancer in European and African populations. Nat Genet (2006) 13.47
Practical aspects of imputation-driven meta-analysis of genome-wide association studies. Hum Mol Genet (2008) 13.26
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet (2007) 12.65
20-year outcomes following conservative management of clinically localized prostate cancer. JAMA (2005) 12.25
Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat Genet (2010) 9.07
Prostate cancer epidemiology. Lancet (2003) 6.30
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet (2008) 6.10
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet (2009) 6.04
Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. Nat Genet (2009) 5.06
Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP. J Natl Cancer Inst (2007) 4.85
Multiple loci on 8q24 associated with prostate cancer susceptibility. Nat Genet (2009) 3.94
Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat Genet (2009) 3.76
Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12. Nat Genet (2008) 3.14
Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. Nat Genet (2010) 2.92
Variation in KLK genes, prostate-specific antigen and risk of prostate cancer. Nat Genet (2008) 2.45
Sequence variants at 22q13 are associated with prostate cancer risk. Cancer Res (2009) 2.27
Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1). J Clin Invest (2003) 1.93
Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility. Proc Natl Acad Sci U S A (2009) 1.81
Two independent prostate cancer risk-associated Loci at 11q13. Cancer Epidemiol Biomarkers Prev (2009) 1.78
Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. Proc Natl Acad Sci U S A (2010) 1.59
Genomewide scan for prostate cancer-aggressiveness loci. Am J Hum Genet (2000) 1.57
A novel prostate cancer susceptibility locus at 19q13. Cancer Res (2009) 1.49
Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3. PLoS One (2011) 1.41
Control of cell survival and proliferation by mammalian eukaryotic initiation factor 4B. Mol Cell Biol (2010) 1.41
The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase. J Biol Chem (2002) 1.23
Genome-wide scan of brothers: replication and fine mapping of prostate cancer susceptibility and aggressiveness loci. Prostate (2003) 1.22
GWAS identifies a common breast cancer risk allele among BRCA1 carriers. Nat Genet (2010) 1.19
Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer. Hum Mol Genet (2011) 1.17
Genome-wide linkage scan for prostate cancer aggressiveness loci using families from the University of Michigan Prostate Cancer Genetics Project. Prostate (2006) 1.17
Confirmation of linkage of prostate cancer aggressiveness with chromosome 19q. Am J Hum Genet (2003) 1.10
Refining the prostate cancer genetic association within the JAZF1 gene on chromosome 7p15.2. Cancer Epidemiol Biomarkers Prev (2010) 0.99
Concordance of survival in family members with prostate cancer. J Clin Oncol (2008) 0.98
Cancer statistics, 2008. CA Cancer J Clin (2008) 86.74
Cancer statistics, 2009. CA Cancer J Clin (2009) 83.57
Finding the missing heritability of complex diseases. Nature (2009) 67.95
Cancer statistics, 2007. CA Cancer J Clin (2007) 53.49
Patterns of somatic mutation in human cancer genomes. Nature (2007) 38.41
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med (2003) 35.39
Cancer statistics, 2006. CA Cancer J Clin (2006) 30.71
Mortality results from a randomized prostate-cancer screening trial. N Engl J Med (2009) 30.05
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA (2002) 28.72
Cancer statistics, 2005. CA Cancer J Clin (2005) 25.65
Radical prostatectomy versus observation for localized prostate cancer. N Engl J Med (2012) 24.06
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med (2004) 23.44
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
International network of cancer genome projects. Nature (2010) 20.35
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet (2007) 19.18
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature (2007) 17.68
Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65
A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. N Engl J Med (2005) 17.32
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Assessing the impact of population stratification on genetic association studies. Nat Genet (2004) 16.28
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Replicating genotype-phenotype associations. Nature (2007) 16.11
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature (2008) 16.10
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Cancer statistics, 2004. CA Cancer J Clin (2004) 15.72
Multiple newly identified loci associated with prostate cancer susceptibility. Nat Genet (2008) 15.43
Cumulative association of five genetic variants with prostate cancer. N Engl J Med (2008) 15.34
Prevalence of prostate cancer among men with a prostate-specific antigen level < or =4.0 ng per milliliter. N Engl J Med (2004) 15.10
Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet (2007) 14.37