Published in J Tissue Eng Regen Med on July 11, 2011
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Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death. Endocrinology (2003) 2.76
Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells. Diabetes (2009) 1.60
{beta}-Cell mass dynamics and islet cell plasticity in human type 2 diabetes. Endocrinology (2010) 1.32
Cross-talk between phosphatidylinositol 3-kinase/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets. Endocrinology (2004) 1.29
Ex vivo expansion of human mesenchymal stem cells in defined serum-free media. Stem Cells Int (2012) 1.20
Donor and isolation variables predicting human islet isolation success. Transplantation (2008) 1.08
Tubular complexes as a source for islet neogenesis in the pancreas of diabetes-prone BB rats. Lab Invest (2005) 1.03
New tissue dissociation protocol for scaled-up production of neural stem cells in suspension bioreactors. Tissue Eng (2004) 1.03
Spinal GABAergic transplants attenuate mechanical allodynia in a rat model of neuropathic pain. Stem Cells (2007) 1.01
Scale-up of breast cancer stem cell aggregate cultures to suspension bioreactors. Biotechnol Prog (2006) 0.99
The effect of extracellular matrix components on the preservation of human islet function in vitro. Biomaterials (2009) 0.99
Long-term in vitro human pancreatic islet culture using three-dimensional microfabricated scaffolds. Biomaterials (2010) 0.94
Amyloid inhibitors enhance survival of cultured human islets. Biochim Biophys Acta (2009) 0.94
Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture. Diabetes (2008) 0.93
Acinar plasticity: development of a novel in vitro model to study human acinar-to-duct-to-islet differentiation. Pancreas (2007) 0.92
Cell cycle kinetics of expanding populations of neural stem and progenitor cells in vitro. Biotechnol Bioeng (2004) 0.91
The engineering of tissues using progenitor cells. Curr Top Dev Biol (2004) 0.91
Identification of growth and attachment factors for the serum-free isolation and expansion of human mesenchymal stromal cells. Cytotherapy (2010) 0.90
Large-scale production of human mesenchymal stem cells for clinical applications. Biotechnol Appl Biochem (2013) 0.89
Using simulation to determine the need for ICU beds for surgery patients. Surgery (2009) 0.89
Tumor necrosis factor-alpha production by human islets leads to postisolation cell death. Transplantation (2006) 0.88
Integrin {alpha}3, but not {beta}1, regulates islet cell survival and function via PI3K/Akt signaling pathways. Endocrinology (2010) 0.88
INGAP peptide improves nerve function and enhances regeneration in streptozotocin-induced diabetic C57BL/6 mice. FASEB J (2004) 0.87
Expansion of mammalian neural stem cells in bioreactors: effect of power input and medium viscosity. Brain Res Dev Brain Res (2002) 0.87
Improved expansion of human bone marrow-derived mesenchymal stem cells in microcarrier-based suspension culture. J Tissue Eng Regen Med (2012) 0.87
Scaled-up production of mammalian neural precursor cell aggregates in computer-controlled suspension bioreactors. Biotechnol Bioeng (2006) 0.84
Morphological and functional studies on submucosal islet transplants in normal and diabetic hamsters. Cell Transplant (2002) 0.84
Enhanced islet expansion by beta-cell proliferation in young diabetes-prone rats fed a protective diet. J Cell Physiol (2010) 0.83
Expansion of human neural precursor cells in large-scale bioreactors for the treatment of neurodegenerative disorders. Biotechnol Prog (2009) 0.83
Identification and characterization of small cells in the adult pancreas: potential progenitor cells? Cell Tissue Res (2002) 0.83
The role of islet neogenesis-associated protein (INGAP) in islet neogenesis. Cell Biochem Biophys (2007) 0.83
Cellular origins of adult human islet in vitro dedifferentiation. Lab Invest (2008) 0.83
Pancreatic islet culture and preservation strategies: advances, challenges, and future outlook. Cell Transplant (2010) 0.82
A review of bioreactor protocols for human neural precursor cell expansion in preparation for clinical trials. Curr Stem Cell Res Ther (2011) 0.82
Dynamic behavior of cells within neurospheres in expanding populations of neural precursors. Brain Res (2006) 0.82
Transforming growth factor beta is a critical regulator of adult human islet plasticity. Mol Endocrinol (2007) 0.81
Large-scale expansion of mammary epithelial stem cell aggregates in suspension bioreactors. Biotechnol Prog (2005) 0.80
Secretome of mesenchymal progenitors from the umbilical cord acts as modulator of neural/glial proliferation and differentiation. Stem Cell Rev (2015) 0.80
Production of islet-like structures from neonatal porcine pancreatic tissue in suspension bioreactors. Biotechnol Prog (2006) 0.79
Bioreactor expansion of human neural precursor cells in serum-free media retains neurogenic potential. Biotechnol Bioeng (2010) 0.79
Neurite outgrowth in dorsal root ganglia induced by islet neogenesis-associated protein peptide involves protein kinase A activation. Neuroreport (2006) 0.78
Epidermal growth factor induces adult human islet cell dedifferentiation. J Endocrinol (2011) 0.78
Insulin-like growth factor II allows prolonged blood glucose normalization with a reduced islet cell mass transplantation. Endocrinology (2003) 0.78
Passaging protocols for mammalian neural stem cells in suspension bioreactors. Biotechnol Prog (2002) 0.78
Islet-neogenesis-associated protein enhances neurite outgrowth from DRG neurons. Biochem Biophys Res Commun (2002) 0.78
Islet-derived progenitors as a source of in vitro islet regeneration. Methods Mol Biol (2009) 0.78
Design and analysis of a long-term live-cell imaging chamber for tracking cellular dynamics within cultured human islets of Langerhans. Biotechnol Bioeng (2007) 0.78
Prospects and challenges for islet regeneration as a treatment for diabetes: a review of islet neogenesis associated protein. J Diabetes Sci Technol (2007) 0.78
Inhibition of caspase-mediated PARP-1 cleavage results in increased necrosis in isolated islets of Langerhans. J Mol Med (Berl) (2004) 0.78
Islet neogenesis: a potential therapeutic tool in type 1 diabetes. Int J Biochem Cell Biol (2005) 0.78
Dielectric spectroscopy for non-invasive monitoring of epithelial cell differentiation within three-dimensional scaffolds. Phys Med Biol (2012) 0.77
Effect of calcium on the proliferation kinetics of synovium-derived mesenchymal stromal cells. Cytotherapy (2013) 0.77
Bioprocessing of human glioblastoma brain cancer tissue. Tissue Eng Part A (2010) 0.77
Transplantation of GABAergic cells derived from bioreactor-expanded human neural precursor cells restores motor and cognitive behavioral deficits in a rodent model of Huntington's disease. Cell Transplant (2012) 0.77
Characterization of human islet-like structures generated from pancreatic precursor cells in culture. Biotechnol Bioeng (2006) 0.76
Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression. J Endocrinol (2006) 0.76
The identification and sequence analysis of a new Reg3gamma and Reg2 in the Syrian golden hamster. Biochim Biophys Acta (2007) 0.76
Block-copolymer micelles as carriers of cell signaling modulators for the inhibition of JNK in human islets of Langerhans. Biomaterials (2009) 0.76
New bioengineering insights into human neural precursor cell expansion in culture. Biotechnol Prog (2011) 0.76
Real time monitoring of biofilm development under flow conditions in porous media. Biofouling (2012) 0.76
Survival, differentiation, and migration of bioreactor-expanded human neural precursor cells in a model of Parkinson disease in rats. Neurosurg Focus (2008) 0.76
Production and characterization of the recombinant Islet Neogenesis Associated Protein (rINGAP). Protein Expr Purif (2009) 0.76
Mechanisms of action of islet neogenesis-associated protein: comparison of the full-length recombinant protein and a bioactive peptide. Am J Physiol Endocrinol Metab (2012) 0.75
A new approach to model the spatiotemporal development of biofilm phase in porous media. Environ Microbiol (2011) 0.75
Optimization of reovirus production from mouse L-929 cells in suspension culture. Biotechnol Bioeng (2004) 0.75
Special issue on Canadian bioengineering research. Biotechnol Prog (2009) 0.75