PubRank

Lloyd C Trotman

Author PubWeight™ 44.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 2005 15.83
2 NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN. Cell 2007 5.20
3 Subtle variations in Pten dose determine cancer susceptibility. Nat Genet 2010 4.19
4 SUMO modification of Huntingtin and Huntington's disease pathology. Science 2004 3.85
5 A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis. J Clin Invest 2010 3.47
6 Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. Cancer Cell 2011 1.74
7 Towards patient-based cancer therapeutics. Nat Biotechnol 2010 1.63
8 Nuclear targeting of adenovirus type 2 requires CRM1-mediated nuclear export. Mol Biol Cell 2005 1.16
9 Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia. J Cell Biol 2012 1.13
10 Turning off AKT: PHLPP as a drug target. Annu Rev Pharmacol Toxicol 2014 1.12
11 PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer. Cancer Res 2012 1.10
12 The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells. J Immunol 2008 1.04
13 PTEN regulation of local and long-range connections in mouse auditory cortex. J Neurosci 2012 0.95
14 RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis. Cancer Discov 2014 0.93
15 Prostate cancer genetic-susceptibility locus on chromosome 20q13 is amplified and coupled to androgen receptor-regulation in metastatic tumors. Mol Cancer Res 2013 0.83
16 PTEN plasticity: how the taming of a lethal gene can go too far. Trends Cell Biol 2013 0.82