Published in Gut on August 16, 2011
Panel-based testing for inherited colorectal cancer: a descriptive study of clinical testing performed by a US laboratory. Clin Genet (2014) 2.33
Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. Gastroenterology (2015) 1.84
Risk of colorectal cancer for carriers of mutations in MUTYH, with and without a family history of cancer. Gastroenterology (2014) 1.01
The molecular genetics of colorectal cancer. Frontline Gastroenterol (2013) 0.90
Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells. Carcinogenesis (2012) 0.87
MUTYH-associated colorectal cancer and adenomatous polyposis. Surg Today (2013) 0.82
Acceleration in colorectal carcinogenesis: the hare, the tortoise or myth? Gut (2012) 0.81
Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes. J Pathol (2015) 0.80
MUTYH-associated polyposis (MAP), the syndrome implicating base excision repair in inherited predisposition to colorectal tumors. Front Oncol (2012) 0.78
Factors Associated With the Performance of Extended Colonic Resection vs. Segmental Resection in Early-Onset Colorectal Cancer: A Population-Based Study. Clin Transl Gastroenterol (2016) 0.75
Oxidative DNA damage induces hypomethylation in a compromised base excision repair colorectal tumourigenesis. Br J Cancer (2017) 0.75
The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis. Oncotarget (2015) 0.75
Increased risk for colorectal adenomas and cancer in mono-allelic MUTYH mutation carriers: results from a cohort of North-African Jews. Fam Cancer (2015) 0.75
An adenovirus type 5 early gene function regulates expression of other early viral genes. Proc Natl Acad Sci U S A (1979) 13.21
Confidential inquiry into quality of care before admission to intensive care. BMJ (1998) 11.32
Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell (1979) 10.95
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34. Science (1997) 6.10
Screening for breast cancer with mammography. Cochrane Database Syst Rev (2006) 5.19
Rickettsia africae, a tick-borne pathogen in travelers to sub-Saharan Africa. N Engl J Med (2001) 5.08
Testing the validity of the Euroqol and comparing it with the SF-36 health survey questionnaire. Qual Life Res (1993) 5.01
Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer). J Med Genet (2007) 4.62
Isolation of deletion and substitution mutants of adenovirus type 5. Cell (1978) 4.29
ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J (1995) 3.93
Minor surgery by general practitioners under the 1990 contract: effects on hospital workload. BMJ (1993) 3.88
Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells. EMBO J (1987) 3.81
YAP1 dependent activation of TRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hydroperoxides. EMBO J (1994) 3.44
The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast. Genes Dev (1996) 3.36
Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1. Genes Dev (1998) 3.27
Peutz-Jeghers syndrome: a systematic review and recommendations for management. Gut (2010) 3.22
Functional analysis of adenovirus-5 host-range deletion mutants defective for transformation of rat embryo cells. Cold Spring Harb Symp Quant Biol (1980) 3.15
Milk intake and bone mineral acquisition in adolescent girls: randomised, controlled intervention trial. BMJ (1997) 3.01
Quality of minor surgery by general practitioners in 1990 and 1991. Br J Gen Pract (1994) 3.00
Efficient lysis of human immunodeficiency virus type 1-infected cells by cytotoxic T lymphocytes. J Virol (1996) 2.85
Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J (1997) 2.84
Molecular genetic advances in tuberous sclerosis. Hum Genet (2000) 2.72
E1A 13S and 12S mRNA products made in Escherichia coli both function as nucleus-localized transcription activators but do not directly bind DNA. Mol Cell Biol (1985) 2.68
Schizosaccharomyces pombe atf1+ encodes a transcription factor required for sexual development and entry into stationary phase. EMBO J (1995) 2.67
Cancer risks in BRCA2 families: estimates for sites other than breast and ovary. J Med Genet (2005) 2.65
Guidelines for the clinical management of familial adenomatous polyposis (FAP). Gut (2008) 2.65
Beckwith-Wiedemann syndrome and assisted reproduction technology (ART). J Med Genet (2003) 2.48
Treatment of health complaints attributed to amalgam. J Dent Res (2008) 2.48
Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: correction for ascertainment. J Med Genet (2005) 2.45
Older persons after hospitalization: a controlled study of home aide service. Am J Public Health (1972) 2.44
Is surveillance of the small bowel indicated for Lynch syndrome families? Gut (2007) 2.42
Use of a transposon (Tndif) to obtain suppressing and nonsuppressing insertions of the dif resolvase site of Escherichia coli. Genes Dev (1996) 2.42
Duodenal adenomatosis in familial adenomatous polyposis. Gut (2004) 2.38
Adenovirus E1a gene product expressed at high levels in Escherichia coli is functional. Science (1984) 2.38
Deletion of the TSC2 and PKD1 genes associated with severe infantile polycystic kidney disease--a contiguous gene syndrome. Nat Genet (1994) 2.35
Differences in risk factors for local and distant recurrence after breast-conserving therapy or mastectomy for stage I and II breast cancer: pooled results of two large European randomized trials. J Clin Oncol (2001) 2.28
Comprehensive mutation analysis of TSC1 and TSC2-and phenotypic correlations in 150 families with tuberous sclerosis. Am J Hum Genet (1999) 2.26
Basement membrane changes in breast cancer detected by immunohistochemical staining for laminin. Cancer Res (1981) 2.21
Facial growth in Cercocebus torquatus: an application of three-dimensional geometric morphometric techniques to the study of morphological variation. J Anat (1998) 2.16
Correlations between mutation site in APC and phenotype of familial adenomatous polyposis (FAP): a review of the literature. Crit Rev Oncol Hematol (2006) 2.13
Effects on quality of life with comprehensive rehabilitation after acute myocardial infarction. Am J Cardiol (1991) 2.13
Improving the sensitivity of the American College of Rheumatology classification criteria for systemic sclerosis. Clin Exp Rheumatol (2007) 2.12
Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins. Nature (1997) 2.10
EAACI position paper on rhinosinusitis and nasal polyps executive summary. Allergy (2005) 2.07
Osteogenesis imperfecta is linked to both type I collagen structural genes. Lancet (1986) 2.07
Antenatal screening in Oxford for fetal neural tube defects. Br J Obstet Gynaecol (1979) 2.06
Characterization and expression of the human alpha beta T cell receptor by using a framework monoclonal antibody. J Immunol (1987) 2.05
Brain glutamate transporter proteins form homomultimers. J Biol Chem (1996) 2.01
Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2. Cardiovasc Res (2001) 1.95
Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells. Science (1995) 1.92
Screening for familial ovarian cancer: poor survival of BRCA1/2 related cancers. J Med Genet (2008) 1.90
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III. Proc Natl Acad Sci U S A (1997) 1.89
The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination. Oncogene (2000) 1.89
Lead-catalyzed cleavage of yeast tRNAPhe mutants. Biochemistry (1990) 1.87
Somatic APC mosaicism: an underestimated cause of polyposis coli. Gut (2007) 1.79
Patients' attitude towards the use of a chaperone in breast examination. Ann R Coll Surg Engl (2008) 1.76
Effect of deletions in adenovirus early region 1 genes upon replication of adeno-associated virus. J Virol (1982) 1.76
A mutation which alters initiation of transcription by RNA polymerase III on the Ad5 chromosome. Cell (1979) 1.75
The transfer RNA identity problem: a search for rules. Science (1994) 1.75
The frequency of a positive family history for colorectal cancer: a population-based study in the Netherlands. Neth J Med (2006) 1.74
Redox control of AP-1-like factors in yeast and beyond. Oncogene (2001) 1.72
Interaction of convulsive ligands with benzodiazepine receptors. Science (1982) 1.72
Structure of an unmodified tRNA molecule. Biochemistry (1989) 1.71
Oxygen or air? Anaesthesia (2001) 1.66
Prediction of protein secondary structure at 80% accuracy. Proteins (2000) 1.65
ABC of intensive care. Criteria for admission. BMJ (1999) 1.65
Long-read sequence analysis of the MECP2 gene in Rett syndrome patients: correlation of disease severity with mutation type and location. Hum Mol Genet (2000) 1.61
Task-dependent influences of attention on the activation of human primary visual cortex. Proc Natl Acad Sci U S A (1998) 1.60
pct1+, which encodes a new DNA-binding partner of p85cdc10, is required for meiosis in the fission yeast Schizosaccharomyces pombe. Genes Dev (1994) 1.60
Vaccination of seronegative volunteers with a human immunodeficiency virus type 1 env/rev DNA vaccine induces antigen-specific proliferation and lymphocyte production of beta-chemokines. J Infect Dis (2000) 1.59
Household crowding a major risk factor for epidemic meningococcal disease in Auckland children. Pediatr Infect Dis J (2000) 1.57
Type II myosin involved in cytokinesis in the fission yeast, Schizosaccharomyces pombe. Cell Motil Cytoskeleton (1997) 1.57
Coexisting somatic promoter hypermethylation and pathogenic MLH1 germline mutation in Lynch syndrome. J Pathol (2008) 1.56
Decision analysis in the surgical treatment of colorectal cancer due to a mismatch repair gene defect. Gut (2003) 1.55
Presumed tuberculous uveitis: diagnosis, management, and outcome. Eye (Lond) (2011) 1.54
Acute hantavirus infection. Lancet (1991) 1.53
Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro. Signaling pathways controlling surface and gene expression. Am J Respir Cell Mol Biol (2000) 1.53
Mapping of functional domains in adenovirus E1A proteins. Proc Natl Acad Sci U S A (1985) 1.53
SARS CTL vaccine candidates; HLA supertype-, genome-wide scanning and biochemical validation. Tissue Antigens (2004) 1.52
[S3-guideline colorectal cancer version 1.0]. Z Gastroenterol (2013) 1.51
p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells. Genes Dev (1998) 1.50
Molecular genetic and phenotypic analysis reveals differences between TSC1 and TSC2 associated familial and sporadic tuberous sclerosis. Hum Mol Genet (1997) 1.49
Stress-activated signalling pathways in yeast. Genes Cells (1998) 1.47
Expression of the human EGF receptor with ligand-stimulatable kinase activity in insect cells using a baculovirus vector. EMBO J (1988) 1.46
Audit of telephone advice in a paediatric accident and emergency department. J Accid Emerg Med (1994) 1.45
Metastases to the breast from extramammary carcinomas. Acta Pathol Microbiol Scand A (1981) 1.45
Economic evaluation of cardiac rehabilitation soon after acute myocardial infarction. Am J Cardiol (1993) 1.44
Phosphorylation of E2F-1 modulates its interaction with the retinoblastoma gene product and the adenoviral E4 19 kDa protein. Cell (1994) 1.44
Flash pulmonary oedema. Lancet (2001) 1.43
The GAP-related domain of tuberin, the product of the TSC2 gene, is a target for missense mutations in tuberous sclerosis. Hum Mol Genet (1997) 1.43
Corpus callosum abnormalities, intellectual disability, speech impairment, and autism in patients with haploinsufficiency of ARID1B. Clin Genet (2011) 1.42
Regional scale impacts of distinct CO(2) additions in the North Sea. Mar Pollut Bull (2008) 1.41