Published in EMBO J on April 18, 1995
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol (1996) 6.91
Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J (1996) 6.07
ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. EMBO J (1995) 4.28
Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases. Microbiol Mol Biol Rev (2006) 3.30
Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1. Genes Dev (1998) 3.27
Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation. EMBO J (1995) 3.19
The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol Cell Biol (2002) 3.08
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J (1998) 3.06
Schizosaccharomyces pombe atf1+ encodes a transcription factor required for sexual development and entry into stationary phase. EMBO J (1995) 2.67
The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor. EMBO J (1996) 2.64
Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase. EMBO J (1996) 2.59
Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors. Mol Cell Biol (1997) 2.58
Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1. EMBO J (1998) 2.54
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase. Proc Natl Acad Sci U S A (1997) 2.46
The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif. Mol Cell Biol (1998) 2.44
Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10. Mol Cell Biol (1996) 2.41
Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase. EMBO J (1996) 2.38
Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors. Mol Cell Biol (1999) 2.36
The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase. EMBO J (1996) 2.22
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity. Proc Natl Acad Sci U S A (1997) 2.21
A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression. J Cell Biol (1997) 2.19
The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light. EMBO J (1996) 2.13
Lytic induction therapy for Epstein-Barr virus-positive B-cell lymphomas. J Virol (2004) 2.11
Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation. EMBO J (1998) 2.08
Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3. Mol Biol Cell (2003) 2.03
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms. EMBO J (2000) 2.00
Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production. J Exp Med (1998) 1.99
Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3. Mol Cell Biol (2000) 1.93
MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6. EMBO J (1996) 1.92
Distinct regulatory proteins control the graded transcriptional response to increasing H(2)O(2) levels in fission yeast Schizosaccharomyces pombe. Mol Biol Cell (2002) 1.86
Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation. EMBO J (1998) 1.83
The structure of mitogen-activated protein kinase p38 at 2.1-A resolution. Proc Natl Acad Sci U S A (1997) 1.83
The herpesvirus transactivator VP16 mimics a human basic domain leucine zipper protein, luman, in its interaction with HCF. J Virol (1998) 1.81
Peroxide sensors for the fission yeast stress-activated mitogen-activated protein kinase pathway. Mol Biol Cell (2001) 1.80
Epstein-Barr virus immediate-early proteins BZLF1 and BRLF1 activate the ATF2 transcription factor by increasing the levels of phosphorylated p38 and c-Jun N-terminal kinases. J Virol (2000) 1.77
Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway. Genes Dev (1997) 1.75
Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase. Proc Natl Acad Sci U S A (1998) 1.66
Multistep phosphorelay proteins transmit oxidative stress signals to the fission yeast stress-activated protein kinase. Mol Biol Cell (2000) 1.66
UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells. EMBO J (1998) 1.65
Independent regulation of JNK/p38 mitogen-activated protein kinases by metabolic oxidative stress in the liver. Proc Natl Acad Sci U S A (1996) 1.63
3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways. Mol Cell Biol (1996) 1.63
CREB controls LAP/C/EBP beta transcription. Mol Cell Biol (1997) 1.62
Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38. EMBO J (2002) 1.60
c-Jun NH(2)-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor. Mol Cell Biol (2003) 1.58
Sequential DNA damage-independent and -dependent activation of NF-kappaB by UV. EMBO J (1998) 1.55
Amino acids control mammalian gene transcription: activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter. Mol Cell Biol (2000) 1.54
Identification of the cyclin D1 gene as a target of activating transcription factor 2 in chondrocytes. Proc Natl Acad Sci U S A (1999) 1.50
p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells. Genes Dev (1998) 1.50
Activation of cJUN N-terminal kinase by herpes simplex virus type 1 enhances viral replication. J Virol (1999) 1.48
Heat stress activates fission yeast Spc1/StyI MAPK by a MEKK-independent mechanism. Mol Biol Cell (1998) 1.48
The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells. Mol Cell Biol (1999) 1.47
Selective activation of the mitogen-activated protein kinase subgroups c-Jun NH2 terminal kinase and p38 by IL-1 and TNF in human articular chondrocytes. J Clin Invest (1996) 1.44
Stress-activated protein kinases are negatively regulated by cell density. EMBO J (1998) 1.43
Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells. Genes Dev (2007) 1.43
Arachidonic acid activates c-jun N-terminal kinase through NADPH oxidase in rabbit proximal tubular epithelial cells. Proc Natl Acad Sci U S A (1997) 1.41
Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization. EMBO J (2006) 1.41
TGFbeta and PTHrP control chondrocyte proliferation by activating cyclin D1 expression. Mol Biol Cell (2001) 1.37
The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents. Mol Cell Biol (1997) 1.36
Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway. EMBO J (1996) 1.36
Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation. Mol Cell Biol (1997) 1.35
Erythroid Krüppel-like factor (EKLF) contains a multifunctional transcriptional activation domain important for inter- and intramolecular interactions. EMBO J (1996) 1.33
A docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substrates. J Biol Chem (2003) 1.31
Cross-linking CD40 on B cells preferentially induces stress-activated protein kinases rather than mitogen-activated protein kinases. EMBO J (1996) 1.31
Global gene expression responses of fission yeast to ionizing radiation. Mol Biol Cell (2003) 1.30
Activation of the BRLF1 promoter and lytic cycle of Epstein-Barr virus by histone acetylation. Nucleic Acids Res (2000) 1.28
Polyamines regulate the stability of activating transcription factor-2 mRNA through RNA-binding protein HuR in intestinal epithelial cells. Mol Biol Cell (2007) 1.28
The carboxy-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain. Mol Cell Biol (1997) 1.25
Adenovirus E4 open reading frame 4 protein autoregulates E4 transcription by inhibiting E1A transactivation of the E4 promoter. J Virol (1996) 1.24
Reduced levels of ATF-2 predispose mice to mammary tumors. Mol Cell Biol (2006) 1.22
Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity. Proc Natl Acad Sci U S A (1997) 1.20
ATF2 - at the crossroad of nuclear and cytosolic functions. J Cell Sci (2012) 1.20
Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: a MLK-3-MKK7-dependent mechanism. Cell Signal (2007) 1.15
Ubiquitination and degradation of ATF2 are dimerization dependent. Mol Cell Biol (1999) 1.14
ATF2 on the double - activating transcription factor and DNA damage response protein. Pigment Cell Res (2007) 1.12
Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation. Mol Cell Biol (1999) 1.11
ATF-2 regulates fat metabolism in Drosophila. Mol Biol Cell (2007) 1.10
Stress-activated protein kinases are involved in coxsackievirus B3 viral progeny release. J Virol (2005) 1.10
ATF2 is required for amino acid-regulated transcription by orchestrating specific histone acetylation. Nucleic Acids Res (2007) 1.09
TIP49b, a regulator of activating transcription factor 2 response to stress and DNA damage. Mol Cell Biol (2001) 1.09
Defective transcription factor activation for proinflammatory gene expression in poly(ADP-ribose) polymerase 1-deficient glia. Proc Natl Acad Sci U S A (2004) 1.06
Multiple roles for acetylation in the interaction of p300 HAT with ATF-2. Biochemistry (2007) 1.05
The role of ATF-2 family transcription factors in adipocyte differentiation: antiobesity effects of p38 inhibitors. Mol Cell Biol (2009) 1.05
Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein. Biochem J (2002) 1.04
Genomic binding profiling of the fission yeast stress-activated MAPK Sty1 and the bZIP transcriptional activator Atf1 in response to H2O2. PLoS One (2010) 1.04
Identification of a novel amino acid response pathway triggering ATF2 phosphorylation in mammals. Mol Cell Biol (2009) 1.01
Drosophila activating transcription factor-2 is involved in stress response via activation by p38, but not c-Jun NH(2)-terminal kinase. Mol Biol Cell (2005) 1.00
Cell stress-induced phosphorylation of ATF2 and c-Jun transcription factors in rat ventricular myocytes. Biochem J (1997) 0.99
Transcription factor ATF2 cooperates with v-Jun to promote growth factor-independent proliferation in vitro and tumor formation in vivo. Mol Cell Biol (1998) 0.98
Staphylococcal PknB as the first prokaryotic representative of the proline-directed kinases. PLoS One (2010) 0.97
The regulatory role of activating transcription factor 2 in inflammation. Mediators Inflamm (2014) 0.96
A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system. Proc Natl Acad Sci U S A (1998) 0.96
Thrombin induces endothelial arginase through AP-1 activation. Am J Physiol Cell Physiol (2009) 0.95
Differential proteomic analysis of mammalian tissues using SILAM. PLoS One (2011) 0.94
Mechanism of IL-1β modulation of intestinal epithelial barrier involves p38 kinase and activating transcription factor-2 activation. J Immunol (2013) 0.94
How do pleiotropic kinase hubs mediate specific signaling by TNFR superfamily members? Immunol Rev (2011) 0.94
Sumoylation delays the ATF7 transcription factor subcellular localization and inhibits its transcriptional activity. Nucleic Acids Res (2007) 0.94
Role of mitogen-activated protein kinase in cardiac hypertrophy and heart failure. Exp Clin Cardiol (2003) 0.94
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress. Proc Natl Acad Sci U S A (2015) 0.93
p38α Signaling Induces Anoikis and Lumen Formation During Mammary Morphogenesis. Sci Signal (2011) 0.93
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell (1994) 16.30
The stress-activated protein kinase subfamily of c-Jun kinases. Nature (1994) 11.45
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell (1989) 11.41
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene. Proc Natl Acad Sci U S A (1986) 10.41
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev (1993) 10.01
ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell (1991) 9.54
Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature (1994) 9.37
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev (1994) 8.92
A vector for expressing GAL4(1-147) fusions in mammalian cells. Nucleic Acids Res (1989) 8.06
The regulation of transcription by phosphorylation. Cell (1992) 7.99
The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1. Cell (1988) 7.76
Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses. Genes Dev (1988) 7.52
Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev (1989) 7.47
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell (1993) 7.37
Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity. Proc Natl Acad Sci U S A (1991) 6.79
Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science (1994) 6.07
MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr Opin Genet Dev (1994) 5.96
Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter. Nature (1992) 5.69
Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature (1994) 5.65
The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science (1992) 5.55
A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein. Cell (1990) 4.67
A nonchromatographic assay for expression of the chloramphenicol acetyltransferase gene in eucaryotic cells. Anal Biochem (1986) 4.60
ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. EMBO J (1995) 4.28
Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements. Cell (1993) 4.01
Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron (1990) 3.70
Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol Cell Biol (1991) 3.70
Functional analysis of a growth factor-responsive transcription factor complex. Cell (1993) 3.66
Retracted Cyclic-AMP-responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains. EMBO J (1990) 3.29
NF-kappa B activation by ultraviolet light not dependent on a nuclear signal. Science (1993) 3.25
Heterodimer formation between CREB and JUN proteins. Oncogene (1990) 3.04
Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein. EMBO J (1993) 2.83
Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains. J Biol Chem (1986) 2.80
Mitogen-activated protein kinases: versatile transducers for cell signaling. Trends Biochem Sci (1992) 2.80
Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors. Curr Opin Cell Biol (1994) 2.76
Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21-base-pair sequence. J Virol (1988) 2.67
Transcriptional activation by the SV40 AP-1 recognition element in yeast is mediated by a factor similar to AP-1 that is distinct from GCN4. Cell (1988) 2.56
Direct cloning of leucine zipper proteins: Jun binds cooperatively to the CRE with CRE-BP1. Oncogene (1990) 2.51
Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains. Nature (1994) 2.42
Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences. Mol Cell Biol (1988) 2.40
mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element. Mol Cell Biol (1990) 2.38
Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73. Mol Cell Biol (1992) 2.34
Transcription factors: a new family gathers at the cAMP response site. Trends Genet (1990) 2.28
Cyclic AMP response element binding proteins: a cornucopia of transcription factors. Mol Endocrinol (1990) 2.16
cAMP response element-binding protein is activated by Ca2+/calmodulin- as well as cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1991) 2.04
Retinoblastoma gene product activates expression of the human TGF-beta 2 gene through transcription factor ATF-2. Nature (1992) 1.93
HTLV-I tax gene product activates transcription via pre-existing cellular factors and cAMP responsive element. J Biol Chem (1989) 1.87
Identification of LRF-1, a leucine-zipper protein that is rapidly and highly induced in regenerating liver. Proc Natl Acad Sci U S A (1991) 1.78
Differential effects of the adenovirus E1A oncogene on members of the AP-1 transcription factor family. Mol Cell Biol (1990) 1.66
Different binding specificities and transactivation of variant CRE's by CREB complexes. Nucleic Acids Res (1994) 1.64
Tax1 induction of the HTLV-I 21 bp enhancer requires cooperation between two cellular DNA-binding proteins. EMBO J (1990) 1.63
Transcriptional activation by the adenovirus larger E1a product is mediated by members of the cellular transcription factor ATF family which can directly associate with E1a. Mol Cell Biol (1993) 1.53
Two distinct forms of active transcription factor CREB (cAMP response element binding protein). Proc Natl Acad Sci U S A (1990) 1.47
Regulating transcription factor activity by phosphorylation. Trends Cell Biol (1992) 1.45
Differential regulation of three members of the ATF/CREB family of DNA-binding proteins. Oncogene (1991) 1.45
Phosphorylation of E2F-1 modulates its interaction with the retinoblastoma gene product and the adenoviral E4 19 kDa protein. Cell (1994) 1.44
v-src induction of the TIS10/PGS2 prostaglandin synthase gene is mediated by an ATF/CRE transcription response element. Mol Cell Biol (1994) 1.42
Activating transcription factor-1 can mediate Ca(2+)- and cAMP-inducible transcriptional activation. J Biol Chem (1993) 1.39
Ultraviolet-radiation induced c-jun gene transcription: two AP-1 like binding sites mediate the response. Photochem Photobiol (1992) 1.37
A new method for the isolation of recombinant baculovirus. Nucleic Acids Res (1992) 1.26
Binding of promoter-associated AP-1 is not altered during induction and subsequent repression of the c-jun promoter by TPA and UV irradiation. Carcinogenesis (1994) 1.19
Cyclic AMP response element-binding protein, CRE-BP1, mediates the E1A-induced but not the Tax-induced trans-activation. Oncogene (1991) 1.18
Interleukin 1 induction of the c-jun promoter. Proc Natl Acad Sci U S A (1993) 1.15
Identification of the functional domains of the transcriptional regulator CRE-BP1. J Biol Chem (1991) 1.06
Structural determinants outside of the leucine zipper influence the interactions of CREB and ATF-2: interaction of CREB with ATF-2 blocks E1a-ATF-2 complex formation. Oncogene (1993) 0.99
Complete putative metal finger and leucine zipper structures of CRE-BP1 are required for the E1A-induced trans-activation. J Biol Chem (1991) 0.86
An adenovirus type 5 early gene function regulates expression of other early viral genes. Proc Natl Acad Sci U S A (1979) 13.21
Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell (1979) 10.95
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Rickettsia africae, a tick-borne pathogen in travelers to sub-Saharan Africa. N Engl J Med (2001) 5.08
Testing the validity of the Euroqol and comparing it with the SF-36 health survey questionnaire. Qual Life Res (1993) 5.01
Isolation of deletion and substitution mutants of adenovirus type 5. Cell (1978) 4.29
Minor surgery by general practitioners under the 1990 contract: effects on hospital workload. BMJ (1993) 3.88
Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells. EMBO J (1987) 3.81
YAP1 dependent activation of TRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hydroperoxides. EMBO J (1994) 3.44
The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast. Genes Dev (1996) 3.36
Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1. Genes Dev (1998) 3.27
Functional analysis of adenovirus-5 host-range deletion mutants defective for transformation of rat embryo cells. Cold Spring Harb Symp Quant Biol (1980) 3.15
Milk intake and bone mineral acquisition in adolescent girls: randomised, controlled intervention trial. BMJ (1997) 3.01
Quality of minor surgery by general practitioners in 1990 and 1991. Br J Gen Pract (1994) 3.00
Efficient lysis of human immunodeficiency virus type 1-infected cells by cytotoxic T lymphocytes. J Virol (1996) 2.85
Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J (1997) 2.84
E1A 13S and 12S mRNA products made in Escherichia coli both function as nucleus-localized transcription activators but do not directly bind DNA. Mol Cell Biol (1985) 2.68
Schizosaccharomyces pombe atf1+ encodes a transcription factor required for sexual development and entry into stationary phase. EMBO J (1995) 2.67
Adenovirus E1a gene product expressed at high levels in Escherichia coli is functional. Science (1984) 2.38
Facial growth in Cercocebus torquatus: an application of three-dimensional geometric morphometric techniques to the study of morphological variation. J Anat (1998) 2.16
Effects on quality of life with comprehensive rehabilitation after acute myocardial infarction. Am J Cardiol (1991) 2.13
Improving the sensitivity of the American College of Rheumatology classification criteria for systemic sclerosis. Clin Exp Rheumatol (2007) 2.12
Sensitive assays for trypsin, elastase, and chymotrypsin using new fluorogenic substrates. Anal Biochem (1977) 2.12
Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins. Nature (1997) 2.10
EAACI position paper on rhinosinusitis and nasal polyps executive summary. Allergy (2005) 2.07
Osteogenesis imperfecta is linked to both type I collagen structural genes. Lancet (1986) 2.07
Antenatal screening in Oxford for fetal neural tube defects. Br J Obstet Gynaecol (1979) 2.06
Characterization and expression of the human alpha beta T cell receptor by using a framework monoclonal antibody. J Immunol (1987) 2.05
Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2. Cardiovasc Res (2001) 1.95
Association of primary sclerosing cholangitis with HLA-B8. Gut (1983) 1.79
Patients' attitude towards the use of a chaperone in breast examination. Ann R Coll Surg Engl (2008) 1.76
Effect of deletions in adenovirus early region 1 genes upon replication of adeno-associated virus. J Virol (1982) 1.76
A mutation which alters initiation of transcription by RNA polymerase III on the Ad5 chromosome. Cell (1979) 1.75
Evidence for accelerated colorectal adenoma--carcinoma progression in MUTYH-associated polyposis? Gut (2011) 1.74
Redox control of AP-1-like factors in yeast and beyond. Oncogene (2001) 1.72
A new fluorogenic substrate for chymotrypsin. Anal Biochem (1976) 1.68
Oxygen or air? Anaesthesia (2001) 1.66
pct1+, which encodes a new DNA-binding partner of p85cdc10, is required for meiosis in the fission yeast Schizosaccharomyces pombe. Genes Dev (1994) 1.60
Household crowding a major risk factor for epidemic meningococcal disease in Auckland children. Pediatr Infect Dis J (2000) 1.57
Type II myosin involved in cytokinesis in the fission yeast, Schizosaccharomyces pombe. Cell Motil Cytoskeleton (1997) 1.57
Presumed tuberculous uveitis: diagnosis, management, and outcome. Eye (Lond) (2011) 1.54
Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro. Signaling pathways controlling surface and gene expression. Am J Respir Cell Mol Biol (2000) 1.53
Acute hantavirus infection. Lancet (1991) 1.53
Mapping of functional domains in adenovirus E1A proteins. Proc Natl Acad Sci U S A (1985) 1.53
p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells. Genes Dev (1998) 1.50
Trypsinogen activation peptides assay in the early prediction of severity of acute pancreatitis. Lancet (1990) 1.49
Stress-activated signalling pathways in yeast. Genes Cells (1998) 1.47
Recurrent intravascular papillary endothelial hyperplasia developing from a pyogenic granuloma. J Eur Acad Dermatol Venereol (2001) 1.46
Expression of the human EGF receptor with ligand-stimulatable kinase activity in insect cells using a baculovirus vector. EMBO J (1988) 1.46
Audit of telephone advice in a paediatric accident and emergency department. J Accid Emerg Med (1994) 1.45
Economic evaluation of cardiac rehabilitation soon after acute myocardial infarction. Am J Cardiol (1993) 1.44
Phosphorylation of E2F-1 modulates its interaction with the retinoblastoma gene product and the adenoviral E4 19 kDa protein. Cell (1994) 1.44
Regional scale impacts of distinct CO(2) additions in the North Sea. Mar Pollut Bull (2008) 1.41
Predictors of health-related quality of life with cardiac rehabilitation after acute myocardial infarction. J Cardiopulm Rehabil (1998) 1.38
An objective study of alternative methods of heparin administration. Thromb Res (1980) 1.38
Trauma: the leading cause of maternal death. J Trauma (1992) 1.36
Supracrystallographic resolution of interactions contributing to enzyme catalysis by use of natural structural variants and reactivity-probe kinetics. Biochem J (1988) 1.35
Time to move towards opt-out testing for HIV in the UK. BMJ (2007) 1.33
What the genome sequence is revealing about trypanosome antigenic variation. Biochem Soc Trans (2005) 1.32
Gram type-specific broad-range PCR amplification for rapid detection of 62 pathogenic bacteria. J Clin Microbiol (1999) 1.32
Inaccurate in vivo plasma potassium measurements due to in vitro changes in unseparated blood. Clin Chem (1984) 1.31
AP-1 transcription factors in yeast. Curr Opin Genet Dev (1999) 1.31
Modulation of p27(Kip1) levels by the cyclin encoded by Kaposi's sarcoma-associated herpesvirus. EMBO J (1999) 1.30
Multiple ErbB-2/Neu Phosphorylation Sites Mediate Transformation through Distinct Effector Proteins. J Biol Chem (2001) 1.29
Psychiatric medication-induced obesity: a review. Obes Rev (2004) 1.28
Physical location of host-range mutations of adenovirus type 5; deletion and marker-rescue mapping. Virology (1980) 1.27
A new method for the isolation of recombinant baculovirus. Nucleic Acids Res (1992) 1.26
Use of local neural tube defect registers to interpret national trends. Arch Dis Child Fetal Neonatal Ed (1994) 1.24
Streptococcus pneumoniae blood culture isolates from patients with and without human immunodeficiency virus infection: alterations in penicillin susceptibilities and in serogroups or serotypes. Clin Infect Dis (1997) 1.23
Dok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak. EMBO J (2001) 1.23
Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function. Mol Psychiatry (2009) 1.22
Neural tube defects 1974-94--down but not out. Arch Dis Child Fetal Neonatal Ed (1996) 1.21
Partial primary structure of the alpha and beta chains of human tumor T-cell receptors. Science (1985) 1.19
Convection warmers--not just hot air. Anaesthesia (1997) 1.19
Depressive symptoms in mid-pregnancy, lifetime stressors and the 5-HTTLPR genotype. Genes Brain Behav (2006) 1.18
Substrate-derived two-protonic-state electrophiles as sensitive kinetic specificity probes for cysteine proteinases. Activation of 2-pyridyl disulphides by hydrogen-bonding. Biochem J (1987) 1.17
Heartsink patients: a study of their general practitioners. Br J Gen Pract (1995) 1.15
Psychiatry and war. Learning lessons from the former Yugoslavia. Br J Psychiatry (1994) 1.13
Deposition and fate of arsenic in iron- and arsenic-enriched reservoir sediments. Environ Sci Technol (2002) 1.12
Randomised controlled trial and parallel economic evaluation of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR). Health Technol Assess (2010) 1.12
Immunogenicity of a recombinant human immunodeficiency virus (HIV)-canarypox vaccine in HIV-seronegative Ugandan volunteers: results of the HIV Network for Prevention Trials 007 Vaccine Study. J Infect Dis (2003) 1.11
Standards for the assay of Creutzfeldt-Jakob disease specimens. J Gen Virol (2004) 1.11
The implications of HIV for the anaesthetist and the intensivist. Anaesthesia (2000) 1.11
Genome-wide association study of Alzheimer's disease with psychotic symptoms. Mol Psychiatry (2011) 1.11
Functional characterization of the fission yeast Start-specific transcription factor Res2. EMBO J (1997) 1.09
Viral cyclin-cyclin-dependent kinase 6 complexes initiate nuclear DNA replication. Mol Cell Biol (2001) 1.09
Partial purification of DNA-polymerase from the non-histone chromatin proteins of rat liver. Nature (1967) 1.09
Achieving treatment goals for schoolchildren with asthma. Arch Dis Child (1997) 1.08
Achieving reuse of computable guideline systems. Stud Health Technol Inform (2001) 1.07
Experimental infection of human nasal mucosal explants with Neisseria meningitidis. J Med Microbiol (1995) 1.06
Identification of gene markers for the prediction of allograft rejection or permanent acceptance. Am J Transplant (2007) 1.05
Cell cycle-regulated transcription in fission yeast: Cdc10-Res protein interactions during the cell cycle and domains required for regulated transcription. Mol Biol Cell (1999) 1.04
A genomewide linkage study of preeclampsia/eclampsia reveals evidence for a candidate region on 4q. Am J Hum Genet (1997) 1.03
Expression of the 35kDa and low molecular weight surfactant-associated proteins in the lungs of infants dying with respiratory distress syndrome. Am J Pathol (1989) 1.03
Clinical aspects of 2009 pandemic influenza A (H1N1) virus infection in Austria. Infection (2011) 1.01
Obstetric skills drills: evaluation of teaching methods. Nurse Educ Today (2007) 0.99
Salivary duct determination in Drosophila: roles of the EGF receptor signalling pathway and the transcription factors fork head and trachealess. Development (1996) 0.99