PubRank

David C Henshall

Author PubWeight™ 63.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Increased hippocampal neurogenesis in Alzheimer's disease. Proc Natl Acad Sci U S A 2003 3.52
2 Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects. Nat Med 2012 1.92
3 Endotoxin preconditioning prevents cellular inflammatory response during ischemic neuroprotection in mice. Stroke 2004 1.79
4 To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways. Prog Neurobiol 2003 1.66
5 CREB-mediated Bcl-2 protein expression after ischemic preconditioning. J Cereb Blood Flow Metab 2005 1.60
6 Endotoxin preconditioning protects against the cytotoxic effects of TNFalpha after stroke: a novel role for TNFalpha in LPS-ischemic tolerance. J Cereb Blood Flow Metab 2007 1.55
7 miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132. Am J Pathol 2011 1.52
8 Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy. J Clin Invest 2004 1.34
9 Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice. Brain Res 2008 1.18
10 Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways. Neurobiol Dis 2008 1.16
11 Differential DNA methylation patterns define status epilepticus and epileptic tolerance. J Neurosci 2012 1.12
12 In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury. J Cereb Blood Flow Metab 2011 1.11
13 Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis. PLoS One 2012 1.10
14 Expression profiling the microRNA response to epileptic preconditioning identifies miR-184 as a modulator of seizure-induced neuronal death. Exp Neurol 2012 1.07
15 Formation of a tumour necrosis factor receptor 1 molecular scaffolding complex and activation of apoptosis signal-regulating kinase 1 during seizure-induced neuronal death. Eur J Neurosci 2003 1.07
16 Characterization of neuronal death induced by focally evoked limbic seizures in the C57BL/6 mouse. J Neurosci Res 2002 1.05
17 Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma. FASEB J 2009 1.03
18 Apoptosis, Bcl-2 family proteins and caspases: the ABCs of seizure-damage and epileptogenesis? Int J Physiol Pathophysiol Pharmacol 2009 1.03
19 CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures. Brain 2013 1.02
20 Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice. FASEB J 2011 1.01
21 Endoplasmic reticulum stress and apoptosis signaling in human temporal lobe epilepsy. J Neuropathol Exp Neurol 2006 0.99
22 NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner. J Neurochem 2007 0.97
23 Cell signaling underlying epileptic behavior. Front Behav Neurosci 2011 0.96
24 Development of a model of seizure-induced hippocampal injury with features of programmed cell death in the BALB/c mouse. J Neurosci Res 2004 0.94
25 Evidence of tumor necrosis factor receptor 1 signaling in human temporal lobe epilepsy. Exp Neurol 2006 0.91
26 BH3-only protein Bid is dispensable for seizure-induced neuronal death and the associated nuclear accumulation of apoptosis-inducing factor. J Neurochem 2010 0.90
27 Depletion of 14-3-3 zeta elicits endoplasmic reticulum stress and cell death, and increases vulnerability to kainate-induced injury in mouse hippocampal cultures. J Neurochem 2008 0.90
28 Experimental neonatal status epilepticus and the development of temporal lobe epilepsy with unilateral hippocampal sclerosis. Am J Pathol 2009 0.89
29 Caspase-3 cleavage and nuclear localization of caspase-activated DNase in human temporal lobe epilepsy. J Cereb Blood Flow Metab 2006 0.88
30 Expression, proteolysis and activation of caspases 6 and 7 during rat C6 glioma cell apoptosis. Neurosci Lett 2002 0.88
31 Convulsant doses of a dopamine D1 receptor agonist result in Erk-dependent increases in Zif268 and Arc/Arg3.1 expression in mouse dentate gyrus. PLoS One 2011 0.87
32 Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079. Epilepsia 2013 0.87
33 Elevated p53 and lower MDM2 expression in hippocampus from patients with intractable temporal lobe epilepsy. Epilepsy Res 2007 0.87
34 Hippocampal damage after intra-amygdala kainic acid-induced status epilepticus and seizure preconditioning-mediated neuroprotection in SJL mice. Epilepsy Res 2010 0.86
35 P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control. Int J Physiol Pathophysiol Pharmacol 2012 0.86
36 Antagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epilepticus. Brain Struct Funct 2014 0.85
37 Bcl-2 homology domain 3-only proteins Puma and Bim mediate the vulnerability of CA1 hippocampal neurons to proteasome inhibition in vivo. Eur J Neurosci 2010 0.85
38 Isoform- and subcellular fraction-specific differences in hippocampal 14-3-3 levels following experimentally evoked seizures and in human temporal lobe epilepsy. J Neurochem 2006 0.85
39 Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection. J Biol Chem 2011 0.85
40 Subcellular distribution of Bcl-2 family proteins and 14-3-3 within the hippocampus during seizure-induced neuronal death in the rat. Neurosci Lett 2004 0.85
41 Seizure preconditioning and epileptic tolerance: models and mechanisms. Int J Physiol Pathophysiol Pharmacol 2009 0.85
42 Mutation of Semaphorin-6A disrupts limbic and cortical connectivity and models neurodevelopmental psychopathology. PLoS One 2011 0.85
43 Upregulation of mitochondrial base-excision repair capability within rat brain after brief ischemia. J Cereb Blood Flow Metab 2003 0.84
44 Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. PLoS One 2013 0.84
45 Protective neuronal induction of ATF5 in endoplasmic reticulum stress induced by status epilepticus. Brain 2013 0.84
46 IgG leakage may contribute to neuronal dysfunction in drug-refractory epilepsies with blood-brain barrier disruption. J Neuropathol Exp Neurol 2012 0.82
47 Detection of 14-3-3zeta in cerebrospinal fluid following experimentally evoked seizures. Biomarkers 2008 0.82
48 Dopamine D1 vs D5 receptor-dependent induction of seizures in relation to DARPP-32, ERK1/2 and GluR1-AMPA signalling. Neuropharmacology 2008 0.81
49 Expression, interaction, and proteolysis of death-associated protein kinase and p53 within vulnerable and resistant hippocampal subfields following seizures. Hippocampus 2004 0.81
50 Effects of transient focal cerebral ischemia in mice deficient in puma. Neurosci Lett 2009 0.81
51 Interaction of 14-3-3 with Bid during seizure-induced neuronal death. J Neurochem 2003 0.80
52 P2X7 receptor inhibition interrupts the progression of seizures in immature rats and reduces hippocampal damage. CNS Neurosci Ther 2014 0.79
53 Kainic acid-induced seizures modulate Akt (SER473) phosphorylation in the hippocampus of dopamine D2 receptor knockout mice. J Mol Neurosci 2012 0.79
54 Expression of neurogenesis genes in human temporal lobe epilepsy with hippocampal sclerosis. Int J Physiol Pathophysiol Pharmacol 2010 0.78
55 Mitochondrial localization of the forkhead box class O transcription factor FOXO3a in brain. J Neurochem 2013 0.78
56 Increased expression of microRNA-29a in ALS mice: functional analysis of its inhibition. J Mol Neurosci 2014 0.78
57 Spatio-temporally restricted blood-brain barrier disruption after intra-amygdala kainic acid-induced status epilepticus in mice. Epilepsy Res 2012 0.78
58 Bi-lateral changes to hippocampal cholesterol levels during epileptogenesis and in chronic epilepsy following focal-onset status epilepticus in mice. Brain Res 2012 0.77
59 Investigating gene promoter methylation in a mouse model of status epilepticus. Methods Mol Biol 2013 0.77
60 Proteomic analysis of 14-3-3 zeta binding proteins in the mouse hippocampus. Int J Physiol Pathophysiol Pharmacol 2012 0.77
61 Overexpression of 14-3-3ζ Increases Brain Levels of C/EBP Homologous Protein CHOP. J Mol Neurosci 2015 0.77
62 Suppression of TNF receptor-1 signaling in an in vitro model of epileptic tolerance. Int J Physiol Pathophysiol Pharmacol 2011 0.76
63 Elevated serum Bcl-2 in children with temporal lobe epilepsy. Seizure 2012 0.76