PubRank

Scott R Rajski

Author PubWeight™ 27.39‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 In situ generation of a bisubstrate analogue for protein arginine methyltransferase 1. J Am Chem Soc 2008 1.42
2 Engineered Streptomyces platensis strains that overproduce antibiotics platensimycin and platencin. Antimicrob Agents Chemother 2009 1.23
3 Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis. Proc Natl Acad Sci U S A 2011 1.15
4 Tirandamycins from Streptomyces sp. 17944 inhibiting the parasite Brugia malayi asparagine tRNA synthetase. Org Lett 2011 1.12
5 Engineered production of iso-migrastatin in heterologous Streptomyces hosts. Bioorg Med Chem 2008 1.11
6 Natural product diversification using a non-natural cofactor analogue of S-adenosyl-L-methionine. J Am Chem Soc 2006 1.10
7 Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency. Bioorg Med Chem Lett 2008 1.08
8 iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase. J Biol Chem 2009 1.08
9 Engineering of Streptomyces platensis MA7339 for overproduction of platencin and congeners. Org Lett 2010 1.05
10 Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration. J Am Chem Soc 2009 1.04
11 Characterization of the tautomycetin biosynthetic gene cluster from Streptomyces griseochromogenes provides new insight into dialkylmaleic anhydride biosynthesis. J Nat Prod 2009 1.03
12 Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600. J Nat Prod 2011 1.00
13 Identification and characterization of a novel estrogenic ligand actinopolymorphol A. Biochem Pharmacol 2010 0.99
14 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis. J Biol Chem 2008 0.96
15 In vivo investigation of the roles of FdmM and FdmM1 in fredericamycin biosynthesis unveiling a new family of oxygenases. J Biol Chem 2009 0.96
16 Design, synthesis, and preliminary biological evaluation of a DNA methyltransferase-directed alkylating agent. Chembiochem 2006 0.95
17 Efficient synthesis of azide-bearing cofactor mimics. J Org Chem 2004 0.94
18 DNA methyltransferase-moderated click chemistry. Org Lett 2005 0.94
19 Identification, synthesis, and enzymology of non-natural glucosinolate chemopreventive candidates. Chembiochem 2008 0.92
20 Conversion of aryl azides to O-alkyl imidates via modified Staudinger ligation. Org Lett 2003 0.90
21 Identification of fredericamycin E from Streptomyces griseus: Insights into fredericamycin A biosynthesis highlighting carbaspirocycle formation. J Nat Prod 2008 0.89
22 Discovery and total synthesis of a new estrogen receptor heterodimerizing actinopolymorphol A from Actinopolymorpha rutilus. Org Lett 2010 0.89
23 Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners. J Nat Prod 2012 0.87
24 Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity. Org Lett 2009 0.87
25 Conversion of DNA methyltransferases into azidonucleosidyl transferases via synthetic cofactors. Nucleic Acids Res 2005 0.85
26 Characterization of FdmV as an amide synthetase for fredericamycin A biosynthesis in Streptomyces griseus ATCC 43944. J Biol Chem 2010 0.83
27 Methyltransferase-directed DNA strand scission. J Am Chem Soc 2005 0.82
28 Cyclic Disulfides as Functional Mimics of the Histone Deacetylase Inhibitor FK-228. Tetrahedron Lett 2007 0.75
29 Tandem acyl carrier protein domains in polyunsaturated fatty acid synthases. Methods Enzymol 2009 0.75
30 o-nitrobenzenesulfonamides in nucleoside synthesis: efficient 5'-aziridination of adenosine. J Org Chem 2005 0.75
31 Co-culture of Marine Invertebrate-Associated Bacteria and Interdisciplinary Technologies Enable Biosynthesis and Discovery of a New Antibiotic, Keyicin. ACS Chem Biol 2017 0.75
32 Symbiosis-inspired approaches to antibiotic discovery. Nat Prod Rep 2017 0.75