Published in Mol Microbiol on September 07, 2011
Cyclic di-GMP: the first 25 years of a universal bacterial second messenger. Microbiol Mol Biol Rev (2013) 4.69
You've come a long way: c-di-GMP signaling. Curr Opin Microbiol (2012) 1.93
Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development. Cell (2014) 1.74
Second messenger regulation of biofilm formation: breakthroughs in understanding c-di-GMP effector systems. Annu Rev Cell Dev Biol (2012) 1.54
Sensing the messenger: the diverse ways that bacteria signal through c-di-GMP. Protein Sci (2012) 1.38
The FleQ protein from Pseudomonas aeruginosa functions as both a repressor and an activator to control gene expression from the pel operon promoter in response to c-di-GMP. Nucleic Acids Res (2012) 1.32
Fluorescence-based reporter for gauging cyclic di-GMP levels in Pseudomonas aeruginosa. Appl Environ Microbiol (2012) 1.24
Cyclic diguanosine monophosphate represses bacterial flagella synthesis by interacting with the Walker A motif of the enhancer-binding protein FleQ. Proc Natl Acad Sci U S A (2013) 1.19
Coordinated cyclic-di-GMP repression of Salmonella motility through YcgR and cellulose. J Bacteriol (2012) 1.18
Cyclic di-AMP impairs potassium uptake mediated by a cyclic di-AMP binding protein in Streptococcus pneumoniae. J Bacteriol (2013) 1.16
Identification and characterization of non-cellulose-producing mutants of Gluconacetobacter hansenii generated by Tn5 transposon mutagenesis. J Bacteriol (2013) 1.13
Cyclic di-GMP inhibits Vibrio cholerae motility by repressing induction of transcription and inducing extracellular polysaccharide production. Mol Microbiol (2013) 1.11
LtmA, a novel cyclic di-GMP-responsive activator, broadly regulates the expression of lipid transport and metabolism genes in Mycobacterium smegmatis. Nucleic Acids Res (2012) 1.07
Clearance of Pseudomonas aeruginosa foreign-body biofilm infections through reduction of the cyclic Di-GMP level in the bacteria. Infect Immun (2013) 1.04
Diversity of Cyclic Di-GMP-Binding Proteins and Mechanisms. J Bacteriol (2016) 0.99
Response of Burkholderia cenocepacia H111 to micro-oxia. PLoS One (2013) 0.92
The exopolysaccharide gene cluster Bcam1330-Bcam1341 is involved in Burkholderia cenocepacia biofilm formation, and its expression is regulated by c-di-GMP and Bcam1349. Microbiologyopen (2012) 0.91
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex. Virulence (2013) 0.91
Bacterial Rotary Export ATPases Are Allosterically Regulated by the Nucleotide Second Messenger Cyclic-di-GMP. J Biol Chem (2015) 0.90
The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi. Front Cell Infect Microbiol (2014) 0.88
Transcriptional activation of the mrkA promoter of the Klebsiella pneumoniae type 3 fimbrial operon by the c-di-GMP-dependent MrkH protein. PLoS One (2013) 0.88
The Cyclic AMP-Vfr Signaling Pathway in Pseudomonas aeruginosa Is Inhibited by Cyclic Di-GMP. J Bacteriol (2015) 0.87
Interbacterial signaling via Burkholderia contact-dependent growth inhibition system proteins. Proc Natl Acad Sci U S A (2016) 0.86
RsmA regulates biofilm formation in Xanthomonas campestris through a regulatory network involving cyclic di-GMP and the Clp transcription factor. PLoS One (2012) 0.85
Cyclic di-nucleotide signaling enters the eukaryote domain. IUBMB Life (2013) 0.82
BrlR from Pseudomonas aeruginosa is a c-di-GMP-responsive transcription factor. Mol Microbiol (2014) 0.82
FleQ DNA Binding Consensus Sequence Revealed by Studies of FleQ-Dependent Regulation of Biofilm Gene Expression in Pseudomonas aeruginosa. J Bacteriol (2015) 0.81
Comparative transcriptomic analysis of the Burkholderia cepacia tyrosine kinase bceF mutant reveals a role in tolerance to stress, biofilm formation, and virulence. Appl Environ Microbiol (2013) 0.81
Engineering of Bacillus subtilis strains to allow rapid characterization of heterologous diguanylate cyclases and phosphodiesterases. Appl Environ Microbiol (2014) 0.81
Capture compound mass spectrometry--a powerful tool to identify novel c-di-GMP effector proteins. J Vis Exp (2015) 0.81
Dissecting novel virulent determinants in the Burkholderia cepacia complex. Virulence (2012) 0.80
A Minimal Threshold of c-di-GMP Is Essential for Fruiting Body Formation and Sporulation in Myxococcus xanthus. PLoS Genet (2016) 0.79
Biofilms 2012: new discoveries and significant wrinkles in a dynamic field. J Bacteriol (2013) 0.79
Identification of potential genetic components involved in the deviant quorum-sensing signaling pathways of Burkholderia glumae through a functional genomics approach. Front Cell Infect Microbiol (2015) 0.79
Cyclic di-GMP: second messenger extraordinaire. Nat Rev Microbiol (2017) 0.79
In-Frame and Unmarked Gene Deletions in Burkholderia cenocepacia via an Allelic Exchange System Compatible with Gateway Technology. Appl Environ Microbiol (2015) 0.78
Global transcriptional analysis of Burkholderia pseudomallei high and low biofilm producers reveals insights into biofilm production and virulence. BMC Genomics (2015) 0.78
Two nucleotide second messengers regulate the production of the Vibrio cholerae colonization factor GbpA. BMC Microbiol (2015) 0.77
Cyclic Dinucleotide-Controlled Regulatory Pathways in Streptomyces Species. J Bacteriol (2016) 0.76
Diguanylate cyclase null mutant reveals that C-Di-GMP pathway regulates the motility and adherence of the extremophile bacterium Acidithiobacillus caldus. PLoS One (2015) 0.76
Sustained sensing as an emerging principle in second messenger signaling systems. Curr Opin Microbiol (2016) 0.76
AraC-like transcriptional activator CuxR binds c-di-GMP by a PilZ-like mechanism to regulate extracellular polysaccharide production. Proc Natl Acad Sci U S A (2017) 0.75
The Phytohormone Ethylene Enhances Cellulose Production, Regulates CRP/FNRKx Transcription and Causes Differential Gene Expression within the Bacterial Cellulose Synthesis Operon of Komagataeibacter (Gluconacetobacter) xylinus ATCC 53582. Front Microbiol (2015) 0.75
Structures of the activator of K. pneumonia biofilm formation, MrkH, indicates PilZ domains involved in c-di-GMP and DNA binding. Proc Natl Acad Sci U S A (2016) 0.75
Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB. Microbiologyopen (2017) 0.75
Extracellular DNA required for bacterial biofilm formation. Science (2002) 8.25
Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J (2003) 5.78
Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutants. Mol Microbiol (2003) 5.31
Antibiotic resistance of bacterial biofilms. Int J Antimicrob Agents (2010) 5.18
Retracted Cell-cell signaling in Xanthomonas campestris involves an HD-GYP domain protein that functions in cyclic di-GMP turnover. Proc Natl Acad Sci U S A (2006) 4.92
A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms. Mol Microbiol (2006) 4.49
The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants. Genome Biol (2008) 3.85
Cell death in Pseudomonas aeruginosa biofilm development. J Bacteriol (2003) 3.74
The N terminus of bacterial elongation factor Tu elicits innate immunity in Arabidopsis plants. Plant Cell (2004) 3.63
Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology (2002) 3.37
Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions. PLoS Pathog (2010) 3.15
Involvement of bacterial migration in the development of complex multicellular structures in Pseudomonas aeruginosa biofilms. Mol Microbiol (2003) 3.05
The versatility and adaptation of bacteria from the genus Stenotrophomonas. Nat Rev Microbiol (2009) 3.00
The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional. Mol Microbiol (2006) 2.94
Role of autolysin-mediated DNA release in biofilm formation of Staphylococcus epidermidis. Microbiology (2007) 2.92
Gene transfer occurs with enhanced efficiency in biofilms and induces enhanced stabilisation of the biofilm structure. Curr Opin Biotechnol (2003) 2.68
Quorum-sensing inhibitors as anti-pathogenic drugs. Int J Med Microbiol (2006) 2.68
Differential regulation of closely related R2R3-MYB transcription factors controls flavonol accumulation in different parts of the Arabidopsis thaliana seedling. Plant J (2007) 2.64
Why chronic wounds will not heal: a novel hypothesis. Wound Repair Regen (2008) 2.58
Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. J Clin Invest (2003) 2.54
Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients. Pediatr Pulmonol (2009) 2.53
Genome sequence and rapid evolution of the rice pathogen Xanthomonas oryzae pv. oryzae PXO99A. BMC Genomics (2008) 2.51
Tumor imaging using a picomolar affinity HER2 binding affibody molecule. Cancer Res (2006) 2.46
Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover. Microbiology (2002) 2.41
TACOA: taxonomic classification of environmental genomic fragments using a kernelized nearest neighbor approach. BMC Bioinformatics (2009) 2.36
Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilms. Environ Microbiol (2008) 2.27
First case of E anophelis outbreak in an intensive-care unit. Lancet (2013) 2.26
Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent. Microbiology (2005) 2.24
Statistical analysis of Pseudomonas aeruginosa biofilm development: impact of mutations in genes involved in twitching motility, cell-to-cell signaling, and stationary-phase sigma factor expression. Appl Environ Microbiol (2002) 2.19
Cyclic di-GMP signaling in bacteria: recent advances and new puzzles. J Bacteriol (2006) 2.13
Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector. J Bacteriol (2005) 2.09
Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes. Microbiology (2009) 2.06
Distribution, organization, and ecology of bacteria in chronic wounds. J Clin Microbiol (2008) 2.05
Effects of iron on DNA release and biofilm development by Pseudomonas aeruginosa. Microbiology (2007) 2.05
Diffusible signals and interspecies communication in bacteria. Microbiology (2008) 2.05
Quorum sensing inhibitors: a bargain of effects. Microbiology (2006) 1.99
Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production. Antimicrob Agents Chemother (2004) 1.99
Food spoilage--interactions between food spoilage bacteria. Int J Food Microbiol (2002) 1.97
The metagenome of a biogas-producing microbial community of a production-scale biogas plant fermenter analysed by the 454-pyrosequencing technology. J Biotechnol (2008) 1.93
Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes. Mol Microbiol (2008) 1.88
The clinical impact of bacterial biofilms. Int J Oral Sci (2011) 1.88
Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa. Microbiology (2007) 1.88
Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD. Antimicrob Agents Chemother (2002) 1.85
MeltDB: a software platform for the analysis and integration of metabolomics experiment data. Bioinformatics (2008) 1.83
Applying insights from biofilm biology to drug development - can a new approach be developed? Nat Rev Drug Discov (2013) 1.82
Characterization of starvation-induced dispersion in Pseudomonas putida biofilms. Environ Microbiol (2005) 1.82
Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model. J Antimicrob Chemother (2012) 1.81
Pathogenomics of Xanthomonas: understanding bacterium-plant interactions. Nat Rev Microbiol (2011) 1.81
Two new complete genome sequences offer insight into host and tissue specificity of plant pathogenic Xanthomonas spp. J Bacteriol (2011) 1.80
Diffusible signal factor-dependent cell-cell signaling and virulence in the nosocomial pathogen Stenotrophomonas maltophilia. J Bacteriol (2007) 1.79
The cAMP receptor-like protein CLP is a novel c-di-GMP receptor linking cell-cell signaling to virulence gene expression in Xanthomonas campestris. J Mol Biol (2009) 1.78
Characterization of starvation-induced dispersion in Pseudomonas putida biofilms: genetic elements and molecular mechanisms. Mol Microbiol (2009) 1.75
Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr(-/-) mice. Antimicrob Agents Chemother (2007) 1.71
Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens. Philos Trans R Soc Lond B Biol Sci (2007) 1.70
Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections. Microbiology (2005) 1.70
Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis. Infect Immun (2005) 1.69
High-resolution transcriptional analysis of the regulatory influence of cell-to-cell signalling reveals novel genes that contribute to Xanthomonas phytopathogenesis. Mol Microbiol (2013) 1.68
Bacterial biofilms: prokaryotic adventures in multicellularity. Curr Opin Microbiol (2003) 1.68
Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections. FEMS Immunol Med Microbiol (2010) 1.68
Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa. Antimicrob Agents Chemother (2008) 1.67
Identity and effects of quorum-sensing inhibitors produced by Penicillium species. Microbiology (2005) 1.67
Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre. Mol Microbiol (2013) 1.67
Phosphorus limitation enhances biofilm formation of the plant pathogen Agrobacterium tumefaciens through the PhoR-PhoB regulatory system. J Bacteriol (2004) 1.67
Multiple roles of biosurfactants in structural biofilm development by Pseudomonas aeruginosa. J Bacteriol (2007) 1.66
Genetic analysis of functions involved in the late stages of biofilm development in Burkholderia cepacia H111. Mol Microbiol (2002) 1.63
Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1. J Bacteriol (2004) 1.62
An update on Pseudomonas aeruginosa biofilm formation, tolerance, and dispersal. FEMS Immunol Med Microbiol (2010) 1.62
Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model. J Infect Dis (2005) 1.62
The genome of Xanthomonas campestris pv. campestris B100 and its use for the reconstruction of metabolic pathways involved in xanthan biosynthesis. J Biotechnol (2008) 1.60
Interspecies signalling via the Stenotrophomonas maltophilia diffusible signal factor influences biofilm formation and polymyxin tolerance in Pseudomonas aeruginosa. Mol Microbiol (2008) 1.57
Nonrandom distribution of Pseudomonas aeruginosa and Staphylococcus aureus in chronic wounds. J Clin Microbiol (2009) 1.55
Cyclic di-GMP signalling in the virulence and environmental adaptation of Xanthomonas campestris. Mol Microbiol (2007) 1.50
Cell-cell signal-dependent dynamic interactions between HD-GYP and GGDEF domain proteins mediate virulence in Xanthomonas campestris. Proc Natl Acad Sci U S A (2010) 1.48
Advances in nucleic acid-based diagnostics of bacterial infections. Clin Chim Acta (2007) 1.46
The HD-GYP domain, cyclic di-GMP signaling, and bacterial virulence to plants. Mol Plant Microbe Interact (2006) 1.46
Differentiation and distribution of colistin- and sodium dodecyl sulfate-tolerant cells in Pseudomonas aeruginosa biofilms. J Bacteriol (2006) 1.46
Bacterial biofilm formation and treatment in soft tissue fillers. Pathog Dis (2014) 1.44
Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients. PLoS One (2010) 1.42
Genome scale analysis of diffusible signal factor regulon in Xanthomonas campestris pv. campestris: identification of novel cell-cell communication-dependent genes and functions. Mol Microbiol (2006) 1.41
Dynamics of development and dispersal in sessile microbial communities: examples from Pseudomonas aeruginosa and Pseudomonas putida model biofilms. FEMS Microbiol Lett (2006) 1.40