Hirofumi Hitomi

Author PubWeight™ 58.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Oxidative stress and diabetic cardiovascular complications. Free Radic Biol Med 2005 2.05
2 Systemic candesartan reduces brain angiotensin II via downregulation of brain renin-angiotensin system. Hypertens Res 2009 1.51
3 Multiphoton imaging of the glomerular permeability of angiotensinogen. J Am Soc Nephrol 2012 1.48
4 Effects of diuretics on sodium-dependent glucose cotransporter 2 inhibitor-induced changes in blood pressure in obese rats suffering from the metabolic syndrome. J Hypertens 2016 1.41
5 Urinary angiotensinogen reflects the activity of intrarenal renin-angiotensin system in patients with IgA nephropathy. Nephrol Dial Transplant 2010 1.32
6 Role of p38 MAPK and MAPKAPK-2 in angiotensin II-induced Akt activation in vascular smooth muscle cells. Am J Physiol Cell Physiol 2004 1.26
7 Mechanisms of reactive oxygen species-dependent downregulation of insulin receptor substrate-1 by angiotensin II. Arterioscler Thromb Vasc Biol 2005 1.22
8 Effects of AT1 receptor blockade on renal injury and mitogen-activated protein activity in Dahl salt-sensitive rats. Kidney Int 2004 1.20
9 The SOD mimetic tempol ameliorates glomerular injury and reduces mitogen-activated protein kinase activity in Dahl salt-sensitive rats. J Am Soc Nephrol 2004 1.16
10 Renal sympathetic denervation suppresses de novo podocyte injury and albuminuria in rats with aortic regurgitation. Circulation 2012 1.13
11 Renal sympathetic nerve responses to tempol in spontaneously hypertensive rats. Hypertension 2003 1.09
12 Relationship between urinary angiotensinogen and salt sensitivity of blood pressure in patients with IgA nephropathy. Hypertension 2011 1.05
13 Role of angiotensin II and reactive oxygen species in cyclosporine A-dependent hypertension. Hypertension 2003 1.04
14 Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria: effect of angiotensin II blockade. J Hypertens 2010 1.04
15 Mineralocorticoid receptor blockade enhances the antiproteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic rats. J Pharmacol Exp Ther 2009 0.98
16 Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via epidermal growth factor receptor-mediated extracellular signal-regulated kinase and Akt activation pathway. J Hypertens 2011 0.95
17 Aldosterone induces vascular insulin resistance by increasing insulin-like growth factor-1 receptor and hybrid receptor. Arterioscler Thromb Vasc Biol 2011 0.94
18 Cilnidipine suppresses podocyte injury and proteinuria in metabolic syndrome rats: possible involvement of N-type calcium channel in podocyte. J Hypertens 2010 0.93
19 Possible contribution of the non-proteolytic activation of prorenin to the development of insulin resistance in fructose-fed rats. Exp Physiol 2009 0.93
20 Effects of mineralocorticoid receptor blockade on glucocorticoid-induced renal injury in adrenalectomized rats. J Hypertens 2011 0.92
21 Aldosterone/Mineralocorticoid receptor stimulation induces cellular senescence in the kidney. Endocrinology 2010 0.92
22 Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats. Am J Hypertens 2012 0.91
23 Effect of efonidipine on TGF-β1-induced cardiac fibrosis through Smad2-dependent pathway in rat cardiac fibroblasts. J Pharmacol Sci 2011 0.91
24 Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells. Exp Cell Res 2008 0.90
25 Mineralocorticoid receptor blockade and calcium channel blockade have different renoprotective effects on glomerular and interstitial injury in rats. Am J Physiol Renal Physiol 2009 0.90
26 Blockade of AT1 receptors protects the blood-brain barrier and improves cognition in Dahl salt-sensitive hypertensive rats. Am J Hypertens 2010 0.89
27 Possible involvement of Rho-kinase in aldosterone-induced vascular smooth muscle cell remodeling. Hypertens Res 2008 0.88
28 Mechanical stretch potentiates angiotensin II-induced proliferation in spontaneously hypertensive rat vascular smooth muscle cells. Hypertens Res 2010 0.87
29 A new method for evaluation of split renal cortical blood flow with contrast echography. Hypertens Res 2002 0.86
30 Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor. Exp Cell Res 2011 0.83
31 Contribution of chymase-dependent angiotensin II formation to the progression of tubulointerstitial fibrosis in obstructed kidneys in hamsters. J Pharmacol Sci 2009 0.83
32 Aldosterone induces p21-regulated apoptosis via increased synthesis and secretion of tumour necrosis factor-α in human proximal tubular cells. Clin Exp Pharmacol Physiol 2012 0.82
33 Add-on aliskiren elicits stronger renoprotection than high-dose valsartan in type 2 diabetic KKAy mice that do not respond to low-dose valsartan. J Pharmacol Sci 2012 0.81
34 Possible involvement of the (pro)renin receptor-dependent system in the development of insulin resistance. Front Biosci (Schol Ed) 2011 0.80
35 Inhibitory effects of a dihydropyridine calcium channel blocker on renal injury in aldosterone-infused rats. J Hypertens 2009 0.80
36 N-type calcium channel inhibition with cilnidipine elicits glomerular podocyte protection independent of sympathetic nerve inhibition. J Pharmacol Sci 2012 0.80
37 Drug discovery for overcoming chronic kidney disease (CKD): pharmacological effects of mineralocorticoid-receptor blockers. J Pharmacol Sci 2009 0.80
38 Effects of calcium channel blockade on angiotensin II-induced peritubular ischemia in rats. J Pharmacol Exp Ther 2005 0.80
39 Blood glucose level and survival in streptozotocin-treated human chymase transgenic mice. Chin J Physiol 2011 0.80
40 Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice. Am J Hypertens 2011 0.79
41 Angiotensin II stimulates superoxide production via both angiotensin AT1A and AT1B receptors in mouse aorta and heart. Eur J Pharmacol 2004 0.79
42 Important aspects of urine sampling for angiotensinogen measurement: time and preservation conditions in healthy individuals. Tohoku J Exp Med 2012 0.79
43 Role of (pro)renin receptor in Ang II-mediated EGF receptor transactivation. Front Biosci (Elite Ed) 2013 0.79
44 Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats. PLoS One 2012 0.78
45 Pathophysiological roles of aldosterone and mineralocorticoid receptor in the kidney. J Pharmacol Sci 2010 0.78
46 Insulin attenuates apoptosis induced by high glucose via the PI3-kinase/Akt pathway in rat peritoneal mesothelial cells. Nephrol Dial Transplant 2008 0.78
47 Aldosterone aggravates glucose intolerance induced by high fructose. Eur J Pharmacol 2013 0.78
48 Involvement of mineralocorticoid receptor in high glucose-induced big mitogen-activated protein kinase 1 activation and mesangial cell proliferation. J Hypertens 2010 0.77
49 Effects of angiotensin II AT₁-receptor blockade on high fat diet-induced vascular oxidative stress and endothelial dysfunction in Dahl salt-sensitive rats. J Pharmacol Sci 2013 0.77
50 New approaches to blockade of the renin-angiotensin-aldosterone system: mineralocorticoid-receptor blockers exert antihypertensive and renoprotective effects independently of the renin-angiotensin system. J Pharmacol Sci 2010 0.77
51 [A successful management of renal transplantation donated by living donor for autosomal dominant polycystic kidney disease having various vascular complications]. Nihon Naika Gakkai Zasshi 2008 0.77
52 [Calcium antagonists: current and future applications based on new evidence. Effects of calcium channel blockers on oxidative stress]. Clin Calcium 2010 0.77
53 Short-Term Calorie Restriction in Early Life Attenuates the Development of Proteinuria but Not Glucose Intolerance in Type 2 Diabetic OLETF Rats. ISRN Endocrinol 2011 0.77
54 Calcium channel blocker enhances beneficial effects of an angiotensin II AT1 receptor blocker against cerebrovascular-renal injury in type 2 diabetic mice. PLoS One 2013 0.77
55 Role of caveolin and heat shock protein 70 interaction in the antioxidative effects of an angiotensin II type 1 receptor blocker in spontaneously hypertensive rats proximal tubules. J Hypertens 2010 0.76
56 Roles of central renin-angiotensin system and afferent renal nerve in the control of systemic hemodynamics in rats. Hypertens Res 2011 0.76
57 Angiotensin II induces human astrocyte senescence through reactive oxygen species production. Hypertens Res 2011 0.76
58 Roles of Na⁺/H⁺ exchanger type 1 and intracellular pH in angiotensin II-induced reactive oxygen species generation and podocyte apoptosis. J Pharmacol Sci 2013 0.76
59 Leptin kinetics during peritoneal dialysis in acutely uraemic rats. Nephrology (Carlton) 2004 0.76
60 Low-density lipoprotein apheresis for haemodialysis patients with peripheral arterial disease reduces reactive oxygen species production via suppression of NADPH oxidase gene expression in leucocytes. Nephrol Dial Transplant 2009 0.75
61 Angiotensin-converting enzyme inhibitor does not suppress renal angiotensin II levels in angiotensin I-infused rats. J Pharmacol Sci 2013 0.75
62 A novel clinical biomarker for myeloperoxidase-antineutrophil cytoplasmic antibody associated glomerulonephritis. Clin Exp Pharmacol Physiol 2010 0.75
63 OS 32-05 EFFECTS OF SGLT2 INHIBITORS ON CIRCADIAN RHYTHM OF BLOOD PRESSURE IN RATS. J Hypertens 2016 0.75
64 The earlier, the better. Hypertens Res 2007 0.75
65 OS 32-05 EFFECTS OF SGLT2 INHIBITORS ON CIRCADIAN RHYTHM OF BLOOD PRESSURE IN RATS. J Hypertens 2016 0.75
66 OS 21-09 DIPPING PATTERN OF BLOOD PRESSURE AND RENAL INJURY IN DAHL SALT-SENSITIVE HYPERTENSIVE RATS. J Hypertens 2016 0.75
67 [Unsuccessful management for renal failure induced by glycogen storage disease type-I (Von Gierke disease) in peritoneal dialysis]. Nihon Naika Gakkai Zasshi 2007 0.75
68 [Mineralocorticoid receptor blocker]. Nihon Yakurigaku Zasshi 2008 0.75
69 OS 21-09 DIPPING PATTERN OF BLOOD PRESSURE AND RENAL INJURY IN DAHL SALT-SENSITIVE HYPERTENSIVE RATS. J Hypertens 2016 0.75
70 OS 11-03 Role of renal nervous activity in the development of renovascular hypertension in rats. J Hypertens 2016 0.75
71 OS 15-05 HEPATOCYTE NUCLEAR FACTOR -5 ACTS AS A GLUCOSE-RESPONSIVE ELEMENT OF HUMAN ANGIOTENSINOGEN PROMOTER. J Hypertens 2016 0.75
72 OS 11-03 Role of renal nervous activity in the development of renovascular hypertension in rats. J Hypertens 2016 0.75
73 OS 15-07 ROLE OF (PRO) RENIN RECEPTOR IN THE ACTIVATION OF WNT/ β-CATENIN PATHWAY IN COLON CANCER. J Hypertens 2016 0.75
74 OS 15-05 HEPATOCYTE NUCLEAR FACTOR -5 ACTS AS A GLUCOSE-RESPONSIVE ELEMENT OF HUMAN ANGIOTENSINOGEN PROMOTER. J Hypertens 2016 0.75
75 OS 15-07 ROLE OF (PRO) RENIN RECEPTOR IN THE ACTIVATION OF WNT/ β-CATENIN PATHWAY IN COLON CANCER. J Hypertens 2016 0.75