Published in Antioxid Redox Signal on October 17, 2011
Tuning of peroxiredoxin catalysis for various physiological roles. Biochemistry (2014) 1.02
Leucine-rich repeat kinase 2 (LRRK2)-deficient rats exhibit renal tubule injury and perturbations in metabolic and immunological homeostasis. PLoS One (2013) 0.98
Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis. Mol Cell Biol (2012) 0.97
Protein carbonylation, mitochondrial dysfunction, and insulin resistance. Adv Nutr (2013) 0.93
Mitochondrial peroxiredoxin III is a potential target for cancer therapy. Int J Mol Sci (2011) 0.90
High-fat diet induces changes in adipose tissue trans-4-oxo-2-nonenal and trans-4-hydroxy-2-nonenal levels in a depot-specific manner. Free Radic Biol Med (2013) 0.88
Oxidative stress and protein carbonylation in adipose tissue - implications for insulin resistance and diabetes mellitus. J Proteomics (2013) 0.88
Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human. EMBO Mol Med (2013) 0.87
Glutathionylated lipid aldehydes are products of adipocyte oxidative stress and activators of macrophage inflammation. Diabetes (2013) 0.87
Redox implications in adipose tissue (dys)function-A new look at old acquaintances. Redox Biol (2015) 0.83
Accuracy of novel diagnostic biomarkers for hepatocellular carcinoma: An update for clinicians (Review). Oncol Rep (2016) 0.83
Mitochondria as therapeutic targets for cancer stem cells. World J Stem Cells (2015) 0.82
Aging and calorie restriction oppositely affect mitochondrial biogenesis through TFAM binding at both origins of mitochondrial DNA replication in rat liver. PLoS One (2013) 0.82
Glutathionylated products of lipid peroxidation: A novel mechanism of adipocyte to macrophage signaling. Adipocyte (2014) 0.79
Lipopolysaccharide binding protein is an adipokine involved in the resilience of the mouse adipocyte to inflammation. Diabetologia (2015) 0.78
Genetics of oxidative stress in obesity. Int J Mol Sci (2014) 0.78
Interplay between oxidant species and energy metabolism. Redox Biol (2015) 0.78
Impact of 3-Amino-1,2,4-Triazole (3-AT)-Derived Increase in Hydrogen Peroxide Levels on Inflammation and Metabolism in Human Differentiated Adipocytes. PLoS One (2016) 0.78
Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects From Diet-Induced Obesity Through Increased Mitochondrial Uncoupling and Biogenesis. Diabetes (2016) 0.78
Nucleoredoxin promotes adipogenic differentiation through regulation of Wnt/β-catenin signaling. J Lipid Res (2014) 0.77
Cell stress proteins in atherothrombosis. Oxid Med Cell Longev (2012) 0.77
Interaction of glutaric aciduria type 1-related glutaryl-CoA dehydrogenase with mitochondrial matrix proteins. PLoS One (2014) 0.76
A novel plasminogen activator inhibitor-1 inhibitor, TM5441, protects against high-fat diet-induced obesity and adipocyte injury in mice. Br J Pharmacol (2016) 0.75
Stress turns on the heat: Regulation of mitochondrial biogenesis and UCP1 by ROS in adipocytes. Adipocyte (2016) 0.75
Involvement of Visceral Adipose Tissue in Immunological Modulation of Inflammatory Cascade in Preeclampsia. Mediators Inflamm (2015) 0.75
Mitochondrial peroxiredoxins are essential in regulating the relationship between Drosophila immunity and aging. Biochim Biophys Acta (2016) 0.75
Featured Article: Accelerated decline of physical strength in peroxiredoxin-3 knockout mice. Exp Biol Med (Maywood) (2016) 0.75
Cytoprotective role of the fatty acid binding protein 4 against oxidative and endoplasmic reticulum stress in 3T3-L1 adipocytes. FEBS Open Bio (2014) 0.75
Splenic Immune Response Is Down-Regulated in C57BL/6J Mice Fed Eicosapentaenoic Acid and Docosahexaenoic Acid Enriched High Fat Diet. Nutrients (2017) 0.75
Plekhs1 and Prdx3 are candidate genes responsible for mild hyperglycemia associated with obesity in a new animal model of F344-fa-nidd6 rat. J Vet Med Sci (2016) 0.75
Proteostasis, oxidative stress and aging. Redox Biol (2017) 0.75
Insulin-stimulated lipid accumulation is inhibited by ROS-scavenging chemicals, but not by the Drp1 inhibitor Mdivi-1. PLoS One (2017) 0.75
METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS. J Biol Chem (1964) 21.04
Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest (2004) 13.42
Obesity and insulin resistance. J Clin Invest (2000) 10.47
Mechanisms linking obesity with cardiovascular disease. Nature (2006) 9.07
An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell (1975) 8.29
Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol (2003) 7.47
Sirt1 protects against high-fat diet-induced metabolic damage. Proc Natl Acad Sci U S A (2008) 5.21
Adipose tissue-derived factors: impact on health and disease. Endocr Rev (2006) 3.16
Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone. Mol Cell Biol (2003) 2.95
The expression of adipogenic genes is decreased in obesity and diabetes mellitus. Proc Natl Acad Sci U S A (2000) 2.82
Diabetes and obesity: the twin epidemics. Nat Med (2006) 2.72
Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach. J Clin Endocrinol Metab (2004) 2.59
Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria. J Biol Chem (2004) 2.14
Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling. Biochem J (2009) 1.94
Inflammatory lipid mediators in adipocyte function and obesity. Nat Rev Endocrinol (2010) 1.87
Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion. J Biol Chem (2009) 1.86
Cellularity of adipose depots in six strains of genetically obese mice. J Lipid Res (1972) 1.84
Overexpression of mitochondrial peroxiredoxin-3 prevents left ventricular remodeling and failure after myocardial infarction in mice. Circulation (2006) 1.72
A proteomic approach for identification of secreted proteins during the differentiation of 3T3-L1 preadipocytes to adipocytes. Mol Cell Proteomics (2002) 1.61
Essential role of mitochondrial function in adiponectin synthesis in adipocytes. Diabetes (2007) 1.55
Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stress. Mol Endocrinol (2008) 1.51
Determination of carbonyl groups in oxidized proteins. Methods Mol Biol (2000) 1.47
In-depth analysis of the adipocyte proteome by mass spectrometry and bioinformatics. Mol Cell Proteomics (2007) 1.45
Secretome of primary cultures of human adipose-derived stem cells: modulation of serpins by adipogenesis. Mol Cell Proteomics (2006) 1.37
Mitochondrial (dys)function in adipocyte (de)differentiation and systemic metabolic alterations. Am J Pathol (2009) 1.33
Reactive oxygen species mediate adipocyte differentiation in mesenchymal stem cells. Life Sci (2011) 1.27
Mitochondrial peroxiredoxin-3 protects hippocampal neurons from excitotoxic injury in vivo. J Neurochem (2003) 1.27
Increased susceptibility of MER5 (peroxiredoxin III) knockout mice to LPS-induced oxidative stress. Biochem Biophys Res Commun (2007) 1.23
Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice. Aging Cell (2008) 1.18
Crucial role of peroxiredoxin III in placental antioxidant defense of mice. FEBS Lett (2008) 1.04
Proteome analysis of adipocyte lipid rafts reveals that gC1qR plays essential roles in adipogenesis and insulin signal transduction. Proteomics (2009) 0.95
Extracellular redox environments regulate adipocyte differentiation. Differentiation (2010) 0.94
Metabolic syndrome and mitochondrial function: molecular replacement and antioxidant supplements to prevent membrane peroxidation and restore mitochondrial function. J Cell Biochem (2007) 0.93
Effect of carbohydrate intake on de novo lipogenesis in human adipose tissue. Am J Physiol (1987) 0.92
Peroxiredoxin III-deficiency sensitizes macrophages to oxidative stress. J Biochem (2009) 0.87
Inhibition of adipogenesis by Tempol in 3T3-L1 cells. Free Radic Biol Med (2010) 0.87
Proteome analysis of adipogenesis. Proteomics (2004) 0.87
Cryopreserved human adipogenic-differentiated pre-adipocytes: a potential new source for adipose tissue regeneration. Cytotherapy (2007) 0.85
Proteomic analysis of adipocyte differentiation: Evidence that alpha2 macroglobulin is involved in the adipose conversion of 3T3 L1 preadipocytes. Proteomics (2004) 0.81
The combination of genetic variations in the PRDX3 gene and dietary fat intake contribute to obesity risk. Obesity (Silver Spring) (2010) 0.81
Proteome analysis for 3T3-L1 adipocyte differentiation. J Microbiol Biotechnol (2008) 0.80
Lipid peroxidation in isolated rat nephron segments. Am J Physiol (1992) 0.80
Reversible inactivation of the tumor suppressor PTEN by H2O2. J Biol Chem (2002) 5.08
Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins. Curr Opin Cell Biol (2005) 3.83
Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling. Cell (2010) 3.82
Two enzymes in one; two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function. Cell (2004) 3.65
Reversing the inactivation of peroxiredoxins caused by cysteine sulfinic acid formation. Science (2003) 3.60
Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors. Proc Natl Acad Sci U S A (2004) 3.49
Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radic Biol Med (2008) 3.38
Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells. J Am Soc Nephrol (2005) 2.72
Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins. Mol Cell Biol (2003) 2.70
Inactivation of human peroxiredoxin I during catalysis as the result of the oxidation of the catalytic site cysteine to cysteine-sulfinic acid. J Biol Chem (2002) 2.68
Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine. J Biol Chem (2004) 2.32
Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II. Nature (2005) 2.29
Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxides. J Biol Chem (2011) 2.25
Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expression. J Exp Med (2002) 2.15
Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria. J Biol Chem (2004) 2.14
Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice. Blood (2003) 2.05
2-Cys peroxiredoxin function in intracellular signal transduction: therapeutic implications. Trends Mol Med (2005) 2.02
Controlled elimination of intracellular H(2)O(2): regulation of peroxiredoxin, catalase, and glutathione peroxidase via post-translational modification. Antioxid Redox Signal (2005) 2.00
Reactive oxygen species-regulated signaling pathways in diabetic nephropathy. J Am Soc Nephrol (2003) 1.92
Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence. J Biol Chem (2003) 1.90
Reduction of cysteine sulfinic acid by sulfiredoxin is specific to 2-cys peroxiredoxins. J Biol Chem (2004) 1.86
Regulation of reactive oxygen species generation in cell signaling. Mol Cells (2011) 1.85
Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2. Mol Cell Biol (2004) 1.82
Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger H₂O₂, and protein chaperones. Antioxid Redox Signal (2011) 1.81
Long lifespan in worms with long telomeric DNA. Nat Genet (2004) 1.72
Angiotensin II mediates high glucose-induced TGF-beta1 and fibronectin upregulation in HPMC through reactive oxygen species. Perit Dial Int (2005) 1.67
Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage. Cell Metab (2012) 1.65
Post-translational modifications and their biological functions: proteomic analysis and systematic approaches. J Biochem Mol Biol (2004) 1.64
Diabetic conditions promote binding of monocytes to vascular smooth muscle cells and their subsequent differentiation. Am J Physiol Heart Circ Physiol (2009) 1.63
Glutathione peroxidase 1 deficiency attenuates allergen-induced airway inflammation by suppressing Th2 and Th17 cell development. Antioxid Redox Signal (2010) 1.62
Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130. J Biol Chem (2002) 1.61
Regulation of peroxiredoxin I activity by Cdc2-mediated phosphorylation. J Biol Chem (2002) 1.54
Intramolecular interaction between phosphorylated tyrosine-783 and the C-terminal Src homology 2 domain activates phospholipase C-gamma1. Proc Natl Acad Sci U S A (2005) 1.53
Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury. Am J Physiol Renal Physiol (2009) 1.52
Molecular mechanism of the reduction of cysteine sulfinic acid of peroxiredoxin to cysteine by mammalian sulfiredoxin. J Biol Chem (2006) 1.52
Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB. J Biol Chem (2003) 1.44
Renal transplantation in sensitized recipients with positive luminex and negative CDC (complement-dependent cytotoxicity) crossmatches. Transpl Int (2012) 1.40
Autologous adipose tissue-derived stem cells treatment demonstrated favorable and sustainable therapeutic effect for Crohn's fistula. Stem Cells (2013) 1.40
Hepatitis B virus infection after renal transplantation in the presence of antibody to hepatitis B surface antigen immunity. J Gastroenterol Hepatol (2004) 1.39
Sestrin 2 is not a reductase for cysteine sulfinic acid of peroxiredoxins. Antioxid Redox Signal (2009) 1.39
Multisite M-phase phosphorylation of Xenopus Wee1A. Mol Cell Biol (2005) 1.37
Strategy for comprehensive identification of post-translational modifications in cellular proteins, including low abundant modifications: application to glyceraldehyde-3-phosphate dehydrogenase. J Proteome Res (2008) 1.37
Feedback control of adrenal steroidogenesis via H2O2-dependent, reversible inactivation of peroxiredoxin III in mitochondria. Mol Cell (2012) 1.34
Human Fas-associated factor 1, interacting with ubiquitinated proteins and valosin-containing protein, is involved in the ubiquitin-proteasome pathway. Mol Cell Biol (2005) 1.33
Irreversible oxidation of the active-site cysteine of peroxiredoxin to cysteine sulfonic acid for enhanced molecular chaperone activity. J Biol Chem (2008) 1.27
Deglutathionylation of 2-Cys peroxiredoxin is specifically catalyzed by sulfiredoxin. J Biol Chem (2009) 1.25
Predictors of kidney volume change and delayed kidney function recovery after donor nephrectomy. J Urol (2010) 1.19
Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2. Mol Cell Biol (2004) 1.17
Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expression by human peritoneal mesothelial cells. Kidney Int (2004) 1.17
Irreversible inactivation of glutathione peroxidase 1 and reversible inactivation of peroxiredoxin II by H2O2 in red blood cells. Antioxid Redox Signal (2010) 1.15
New algorithm for the identification of intact disulfide linkages based on fragmentation characteristics in tandem mass spectra. J Proteome Res (2010) 1.14
Cytosolic peroxiredoxin attenuates the activation of Jnk and p38 but potentiates that of Erk in Hela cells stimulated with tumor necrosis factor-alpha. J Biol Chem (2003) 1.14
Reactive oxygen species mediate high glucose-induced plasminogen activator inhibitor-1 up-regulation in mesangial cells and in diabetic kidney. Kidney Int (2005) 1.13
Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions. Biochem J (2009) 1.12
Novel oxidative modifications in redox-active cysteine residues. Mol Cell Proteomics (2010) 1.12
Role of sulfiredoxin as a regulator of peroxiredoxin function and regulation of its expression. Free Radic Biol Med (2012) 1.11
Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP. Nat Struct Mol Biol (2004) 1.11
Mechanism of tyrosine phosphorylation and activation of phospholipase C-gamma 1. Tyrosine 783 phosphorylation is not sufficient for lipase activation. J Biol Chem (2004) 1.11
Sulfiredoxin Translocation into Mitochondria Plays a Crucial Role in Reducing Hyperoxidized Peroxiredoxin III. J Biol Chem (2009) 1.11
Activity assay of mammalian 2-cys peroxiredoxins using yeast thioredoxin reductase system. Anal Biochem (2005) 1.09
Protein glutathionylation in the regulation of peroxiredoxins: a family of thiol-specific peroxidases that function as antioxidants, molecular chaperones, and signal modulators. Antioxid Redox Signal (2012) 1.09
Laminar shear stress up-regulates peroxiredoxins (PRX) in endothelial cells: PRX 1 as a mechanosensitive antioxidant. J Biol Chem (2007) 1.08
Identification and characterization of TRP14, a thioredoxin-related protein of 14 kDa. New insights into the specificity of thioredoxin function. J Biol Chem (2003) 1.08
MODi: a powerful and convenient web server for identifying multiple post-translational peptide modifications from tandem mass spectra. Nucleic Acids Res (2006) 1.08
Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice. Circ Res (2011) 1.08
Membrane targeting of C2 domains of phospholipase C-delta isoforms. J Biol Chem (2001) 1.07
Cytosolic Hsp60 is involved in the NF-kappaB-dependent survival of cancer cells via IKK regulation. PLoS One (2010) 1.06
Wnt/beta-catenin signaling: a novel target for therapeutic intervention of fibrotic kidney disease. Arch Pharm Res (2010) 1.05
Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver. Hepatology (2011) 1.05
Catalase deficiency accelerates diabetic renal injury through peroxisomal dysfunction. Diabetes (2012) 1.05
Reactive oxygen species mediate TGF-beta1-induced plasminogen activator inhibitor-1 upregulation in mesangial cells. Biochem Biophys Res Commun (2003) 1.05
Risk factors associated with the onset and progression of posttransplantation diabetes in renal allograft recipients. Diabetes Care (2007) 1.04
Roles of TRP14, a thioredoxin-related protein in tumor necrosis factor-alpha signaling pathways. J Biol Chem (2003) 1.04
Association of genetic variations in CCR5 and its ligand, RANTES with clearance of hepatitis B virus in Korea. J Med Virol (2006) 1.03
Enhancement of adipose tissue formation by implantation of adipogenic-differentiated preadipocytes. Biochem Biophys Res Commun (2006) 1.03
Unrestrictive identification of multiple post-translational modifications from tandem mass spectrometry using an error-tolerant algorithm based on an extended sequence tag approach. Mol Cell Proteomics (2008) 1.02
Multiple functions of Nm23-H1 are regulated by oxido-reduction system. PLoS One (2009) 1.02
Glutathionylation of peroxiredoxin I induces decamer to dimers dissociation with concomitant loss of chaperone activity. Biochemistry (2011) 1.02
Positive feedback loop between plasminogen activator inhibitor-1 and transforming growth factor-beta1 during renal fibrosis in diabetes. Am J Nephrol (2009) 1.02
Mutagenesis and modeling of the peroxiredoxin (Prx) complex with the NMR structure of ATP-bound human sulfiredoxin implicate aspartate 187 of Prx I as the catalytic residue in ATP hydrolysis. Biochemistry (2006) 1.01
Mechanism of angiotensin II-induced superoxide production in cells reconstituted with angiotensin type 1 receptor and the components of NADPH oxidase. J Biol Chem (2007) 1.01
Structure and interaction of ubiquitin-associated domain of human Fas-associated factor 1. Protein Sci (2009) 0.99