Published in Nucleic Acids Res on September 13, 2011
Roles of F-box proteins in cancer. Nat Rev Cancer (2014) 1.51
Analysis of long-range chromatin interactions using Chromosome Conformation Capture. Methods (2012) 1.23
The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions. Breast Cancer Res (2011) 1.05
The gene desert mammary carcinoma susceptibility locus Mcs1a regulates Nr2f1 modifying mammary epithelial cell differentiation and proliferation. PLoS Genet (2013) 0.79
Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis. Semin Cancer Biol (2015) 0.78
The Non-coding Mammary Carcinoma Susceptibility Locus, Mcs5c, Regulates Pappa Expression via Age-Specific Chromatin Folding and Allele-Dependent DNA Methylation. PLoS Genet (2016) 0.78
Small molecule therapeutics targeting F-box proteins in cancer. Semin Cancer Biol (2015) 0.77
Rats: gnawing through the barriers to understanding genetic susceptibility and breast cancer. Breast Cancer Res (2011) 0.76
Genetically determined inflammatory-response related cytokine and chemokine transcript profiles between mammary carcinoma resistant and susceptible rat strains. Cytokine (2012) 0.75
High-resolution profiling of histone methylations in the human genome. Cell (2007) 85.74
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
Capturing chromosome conformation. Science (2002) 23.93
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
CTCF: master weaver of the genome. Cell (2009) 15.09
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature (2000) 14.91
Looping and interaction between hypersensitive sites in the active beta-globin locus. Mol Cell (2002) 11.35
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet (2007) 10.81
The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell (1999) 9.74
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. Nat Genet (2009) 8.44
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet (2008) 7.65
Genome-wide association study identifies five new breast cancer susceptibility loci. Nat Genet (2010) 7.62
Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains. Genome Res (2008) 7.41
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30
CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes Dev (2006) 6.32
Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus. Nature (2009) 5.96
Allele-specific up-regulation of FGFR2 increases susceptibility to breast cancer. PLoS Biol (2008) 3.49
A chromatin insulator determines the nuclear localization of DNA. Mol Cell (2000) 3.28
CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus. Immunity (2009) 2.24
Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus. Proc Natl Acad Sci U S A (2011) 2.15
Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk. Proc Natl Acad Sci U S A (2007) 1.29
Genetic loci controlling breast cancer susceptibility in the Wistar-Kyoto rat. Genetics (2001) 1.29
Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer. Cancer Epidemiol Biomarkers Prev (2009) 1.15
Fine mapping reveals multiple loci and a possible epistatic interaction within the mammary carcinoma susceptibility quantitative trait locus, Mcs5. Cancer Res (2005) 1.14
The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions. Breast Cancer Res (2011) 1.05
Changes in the DNA methylation profile of the rat H19 gene upstream region during development and transgenic hepatocarcinogenesis and its role in the imprinted transcriptional regulation of the H19 gene. Mol Carcinog (2004) 1.04
Physical evidence of Mcs5, a QTL controlling mammary carcinoma susceptibility, in congenic rats. Carcinogenesis (2003) 0.99
International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol (2011) 21.49
Progress and prospects in rat genetics: a community view. Nat Genet (2008) 6.01
Canadian Association of Gastroenterology and the Canadian Digestive Health Foundation: Guidelines on colon cancer screening. Can J Gastroenterol (2004) 5.09
EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments. Bioinformatics (2013) 4.79
Parenteral anticoagulants: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest (2008) 3.36
Production of knockout rats using ENU mutagenesis and a yeast-based screening assay. Nat Biotechnol (2003) 2.69
International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society: international multidisciplinary classification of lung adenocarcinoma: executive summary. Proc Am Thorac Soc (2011) 2.39
A comparison of the diagnostic accuracy of 18F-FDG PET and CT in the characterization of solitary pulmonary nodules. J Nucl Med (2008) 1.95
A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer. Proc Natl Acad Sci U S A (2007) 1.81
Practice Audit in Gastroenterology (PAGE) program: a novel approach to continuing professional development. Can J Gastroenterol (2006) 1.37
Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk. Proc Natl Acad Sci U S A (2007) 1.29
Fine mapping reveals multiple loci and a possible epistatic interaction within the mammary carcinoma susceptibility quantitative trait locus, Mcs5. Cancer Res (2005) 1.14
The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions. Breast Cancer Res (2011) 1.05
Colonoscopy quality assurance in Ontario: Systematic review and clinical practice guideline. Can J Gastroenterol Hepatol (2014) 1.01
Physical evidence of Mcs5, a QTL controlling mammary carcinoma susceptibility, in congenic rats. Carcinogenesis (2003) 0.99
Mammary glands of sexually immature rats are more susceptible than those of mature rats to the carcinogenic, lethal, and mutagenic effects of N-nitroso-N-methylurea. Mol Carcinog (2005) 0.98
Histological 'progression' from low (LSIL) to high (HSIL) squamous intraepithelial lesion is an uncommon event and an indication for quality assurance review. Mod Pathol (2010) 0.93
Neu-induced retroviral rat mammary carcinogenesis: a novel chemoprevention model for both hormonally responsive and nonresponsive mammary carcinomas. Cancer Res (2006) 0.91
Physical confirmation and mapping of overlapping rat mammary carcinoma susceptibility QTLs, Mcs2 and Mcs6. PLoS One (2011) 0.88
Quantification of epithelial cell differentiation in mammary glands and carcinomas from DMBA- and MNU-exposed rats. PLoS One (2011) 0.87
Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Raf-independent fashion. Clin Cancer Res (2003) 0.85
A short-term rat mammary carcinogenesis model for the prevention of hormonally responsive and nonresponsive in situ carcinomas. Cancer Prev Res (Phila) (2009) 0.84
Genetically engineered rat models for breast cancer. Breast Dis (2007) 0.83
Bile acid malabsorption in chronic diarrhea: pathophysiology and treatment. Can J Gastroenterol (2013) 0.81
Mcs5c: a mammary carcinoma susceptibility locus located in a gene desert that associates with tenascin C expression. Cancer Prev Res (Phila) (2011) 0.80
Decreased susceptibility to NMU-induced mammary carcinogenesis in transgenic rats carrying multiple copies of a rat ras gene driven by the rat Harvey ras promoter. Oncogene (2002) 0.80
Phase I trial of perillyl alcohol administered four times daily continuously. Cancer Chemother Pharmacol (2003) 0.80
The gene desert mammary carcinoma susceptibility locus Mcs1a regulates Nr2f1 modifying mammary epithelial cell differentiation and proliferation. PLoS Genet (2013) 0.79
Chemopreventive effects of celecoxib are limited to hormonally responsive mammary carcinomas in the neu-induced retroviral rat model. Breast Cancer Res (2008) 0.78
Methylguanine methyltransferase activity deficiency in immature rat mammary epithelial cells parallels increased carcinogenic susceptibility. Mol Carcinog (2005) 0.77
Effective flow cytometric phenotyping of cells using minimal amounts of antibody. Biotechniques (2012) 0.77
Omalizumab for severe allergic asthma: dollars and sense. J Allergy Clin Immunol (2007) 0.76
Evaluation of patients with small, subcentimeter nodules. Semin Respir Crit Care Med (2008) 0.76
Outpatient screening endoscopy: why not the standard of care? Interview by Paul Adams. Can J Gastroenterol (2009) 0.75
Freund's vaccine adjuvant promotes Her2/neu breast cancer. BMC Cancer (2009) 0.75
A Qualitative Pilot Study of Pediatricians' Approach to Childhood Obesity. WMJ (2016) 0.75
Efficient poling of electro-optic polymers in thin films and silicon slot waveguides by detachable pyroelectric crystals. Adv Mater (2011) 0.75
A high-responsivity photodetector absent metal-germanium direct contact. Opt Express (2014) 0.75
Playing the odds: lung cancer surveillance after curative surgery. Curr Opin Pulm Med (2017) 0.75