| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The sigma-1 receptor chaperone as an inter-organelle signaling modulator.
|
Trends Pharmacol Sci
|
2010
|
2.11
|
|
2
|
Deregulation of hypothalamic-pituitary-adrenal axis functions in an Alzheimer's disease rat model.
|
Neurobiol Aging
|
2012
|
1.49
|
|
3
|
Involvement of the sigma(1) receptor in cocaine-induced conditioned place preference: possible dependence on dopamine uptake blockade.
|
Neuropsychopharmacology
|
2002
|
1.39
|
|
4
|
Differential effects of sigma1 receptor blockade on self-administration and conditioned reinstatement motivated by cocaine vs natural reward.
|
Neuropsychopharmacology
|
2007
|
1.32
|
|
5
|
Brain-derived neurotrophic factor and hypothalamic-pituitary-adrenal axis adaptation processes in a depressive-like state induced by chronic restraint stress.
|
Mol Cell Neurosci
|
2010
|
1.13
|
|
6
|
The sigma1 protein as a target for the non-genomic effects of neuro(active)steroids: molecular, physiological, and behavioral aspects.
|
J Pharmacol Sci
|
2006
|
1.12
|
|
7
|
The sigma1 (sigma1) receptor activation is a key step for the reactivation of cocaine conditioned place preference by drug priming.
|
Psychopharmacology (Berl)
|
2004
|
1.09
|
|
8
|
Oxidative stress, inflammation, and autophagic stress as the key mechanisms of premature age-related hearing loss in SAMP8 mouse Cochlea.
|
Antioxid Redox Signal
|
2011
|
1.05
|
|
9
|
Sigma 1 receptor-related neuroactive steroids modulate cocaine-induced reward.
|
J Neurosci
|
2003
|
1.03
|
|
10
|
Anxiolytic properties of green tea polyphenol (-)-epigallocatechin gallate (EGCG).
|
Brain Res
|
2006
|
1.00
|
|
11
|
Time-course and regional analyses of the physiopathological changes induced after cerebral injection of an amyloid β fragment in rats.
|
Am J Pathol
|
2011
|
0.98
|
|
12
|
Late N-acetylcysteine treatment prevents the deficits induced in the offspring of dams exposed to an immune stress during gestation.
|
Hippocampus
|
2008
|
0.97
|
|
13
|
Neurodevelopmental damage after prenatal infection: role of oxidative stress in the fetal brain.
|
Free Radic Biol Med
|
2007
|
0.95
|
|
14
|
Sex differences in learning deficits induced by prenatal stress in juvenile rats.
|
Behav Brain Res
|
2004
|
0.94
|
|
15
|
Involvement of the sigma 1 receptor in the modulation of dopaminergic transmission by amantadine.
|
Eur J Neurosci
|
2004
|
0.92
|
|
16
|
Antiamnesic and neuroprotective effects of the aminotetrahydrofuran derivative ANAVEX1-41 against amyloid beta(25-35)-induced toxicity in mice.
|
Neuropsychopharmacology
|
2008
|
0.91
|
|
17
|
Neuroactive steroids modulate HPA axis activity and cerebral brain-derived neurotrophic factor (BDNF) protein levels in adult male rats.
|
Psychoneuroendocrinology
|
2007
|
0.90
|
|
18
|
Phosphatidylethanol accumulation promotes intestinal hyperplasia by inducing ZONAB-mediated cell density increase in response to chronic ethanol exposure.
|
Mol Cancer Res
|
2007
|
0.90
|
|
19
|
Antiamnesic and neuroprotective effects of donepezil against learning impairments induced in mice by exposure to carbon monoxide gas.
|
J Pharmacol Exp Ther
|
2006
|
0.89
|
|
20
|
Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma 1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative.
|
J Psychopharmacol
|
2010
|
0.89
|
|
21
|
Blockade of Tau hyperphosphorylation and Aβ₁₋₄₂ generation by the aminotetrahydrofuran derivative ANAVEX2-73, a mixed muscarinic and σ₁ receptor agonist, in a nontransgenic mouse model of Alzheimer's disease.
|
Neuropsychopharmacology
|
2013
|
0.88
|
|
22
|
Beneficial effects of the sigma1 receptor agonists igmesine and dehydroepiandrosterone against learning impairments in rats prenatally exposed to cocaine.
|
Neurotoxicol Teratol
|
2004
|
0.85
|
|
23
|
Alteration of working memory but not in anxiety or stress response in p300/CBP associated factor (PCAF) histone acetylase knockout mice bred on a C57BL/6 background.
|
Neurosci Lett
|
2010
|
0.85
|
|
24
|
Preserved sigma1 (sigma1) receptor expression and behavioral efficacy in the aged C57BL/6 mouse.
|
Neurobiol Aging
|
2003
|
0.85
|
|
25
|
Neuroprotective effects of donepezil against Aβ42-induced neuronal toxicity are mediated through not only enhancing PP2A activity but also regulating GSK-3β and nAChRs activity.
|
J Neurochem
|
2013
|
0.84
|
|
26
|
The ocular anomalies in a cystinosis animal model mimic disease pathogenesis.
|
Pediatr Res
|
2007
|
0.84
|
|
27
|
Alzheimer's disease related markers, cellular toxicity and behavioral deficits induced six weeks after oligomeric amyloid-β peptide injection in rats.
|
PLoS One
|
2013
|
0.84
|
|
28
|
The three-panel runway maze adapted to Microcebus murinus reveals age-related differences in memory and perseverance performances.
|
Neurobiol Learn Mem
|
2010
|
0.83
|
|
29
|
Sigma1 receptor ligands and related neuroactive steroids interfere with the cocaine-induced state of memory.
|
Neuropsychopharmacology
|
2005
|
0.83
|
|
30
|
Memory impairments and oxidative stress in the hippocampus of in-utero cocaine-exposed rats.
|
Neuroreport
|
2005
|
0.83
|
|
31
|
Improving Alzheimer's Disease-Related Cognitive Deficits with sigma1 Receptor Agonists.
|
Drug News Perspect
|
2002
|
0.82
|
|
32
|
Attenuation by a sigma1 (sigma1) receptor agonist of the learning and memory deficits induced by a prenatal restraint stress in juvenile rats.
|
Br J Pharmacol
|
2004
|
0.82
|
|
33
|
Evidence for sigma-1-like receptors in isolated rat liver mitochondrial membranes.
|
Br J Pharmacol
|
2002
|
0.82
|
|
34
|
Behavioural phenotyping of knockout mice for the sigma-1 (σ₁) chaperone protein revealed gender-related anxiety, depressive-like and memory alterations.
|
J Psychopharmacol
|
2011
|
0.82
|
|
35
|
Nitric oxide and oxidative stress in the brain of rats exposed in utero to cocaine.
|
Ann N Y Acad Sci
|
2006
|
0.82
|
|
36
|
Compensatory effect by sigma1 (sigma1) receptor stimulation during alcohol withdrawal in mice performing an object recognition task.
|
Behav Brain Res
|
2005
|
0.81
|
|
37
|
Dextromethorphan attenuates trimethyltin-induced neurotoxicity via sigma1 receptor activation in rats.
|
Neurochem Int
|
2007
|
0.81
|
|
38
|
The γ-secretase inhibitor 2-[(1R)-1-[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl) amino]ethyl-5-fluorobenzenebutanoic acid (BMS-299897) alleviates Aβ1-42 seeding and short-term memory deficits in the Aβ25-35 mouse model of Alzheimer's disease.
|
Eur J Pharmacol
|
2012
|
0.81
|
|
39
|
Increased amyloid-β peptide-induced memory deficits in phospholipid transfer protein (PLTP) gene knockout mice.
|
Neuropsychopharmacology
|
2012
|
0.80
|
|
40
|
Enhanced antidepressant efficacy of sigma1 receptor agonists in rats after chronic intracerebroventricular infusion of beta-amyloid-(1-40) protein.
|
Eur J Pharmacol
|
2004
|
0.80
|
|
41
|
Enhanced antidepressant effect of sigma(1) (sigma(1)) receptor agonists in beta(25-35)-amyloid peptide-treated mice.
|
Behav Brain Res
|
2002
|
0.80
|
|
42
|
The antidepressant-like effect induced by the sigma(1) (sigma(1)) receptor agonist igmesine involves modulation of intracellular calcium mobilization.
|
Psychopharmacology (Berl)
|
2002
|
0.79
|
|
43
|
Strain differences in sigma(1) receptor-mediated behaviours are related to neurosteroid levels.
|
Eur J Neurosci
|
2002
|
0.79
|
|
44
|
Pharmacological interaction with the sigma1 (σ1)-receptor in the acute behavioral effects of antidepressants.
|
J Pharmacol Sci
|
2011
|
0.78
|
|
45
|
Age-related expression of sigma1 receptors and antidepressant efficacy of a selective agonist in the senescence-accelerated (SAM) mouse.
|
J Neurosci Res
|
2005
|
0.78
|
|
46
|
Behavioral phenotyping of heterozygous acetylcholinesterase knockout (AChE+/-) mice showed no memory enhancement but hyposensitivity to amnesic drugs.
|
Behav Brain Res
|
2009
|
0.77
|
|
47
|
The effects of sigma (σ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice.
|
Br J Pharmacol
|
2015
|
0.77
|
|
48
|
The antidepressant-like effect of the 3β-hydroxysteroid dehydrogenase inhibitor trilostane involves a regulation of β-type estrogen receptors.
|
Psychopharmacology (Berl)
|
2010
|
0.76
|
|
49
|
The antidepressant-like effects of the 3β-hydroxysteroid dehydrogenase inhibitor trilostane in mice is related to changes in neuroactive steroid and monoamine levels.
|
Neuropharmacology
|
2011
|
0.76
|
|
50
|
Tic hydantoin sigma-1 agonist: pharmacological characterization on cocaine-induced stimulant and appetitive effects.
|
Eur Neuropsychopharmacol
|
2009
|
0.76
|
|
51
|
The 3beta-hydroxysteroid dehydrogenase inhibitor trilostane shows antidepressant properties in mice.
|
Psychoneuroendocrinology
|
2008
|
0.75
|
|
52
|
Drug discovery: phosphinolactone, in vivo bioisostere of the lactol group.
|
Org Biomol Chem
|
2010
|
0.75
|
|
53
|
Hyposensitivity to the amnesic effects of scopolamine or amyloid beta(25-35) peptide in heterozygous acetylcholinesterase knockout (AChE(+/-)) mice.
|
Chem Biol Interact
|
2008
|
0.75
|
|
54
|
Corrigendum: Masculinised Behaviour of XY Females in a Mammal with Naturally Occurring Sex Reversal.
|
Sci Rep
|
2016
|
0.75
|