PubRank

Eric Y Denkers

Author PubWeight™ 47.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. J Immunol 2002 3.12
2 Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism. Nat Rev Immunol 2006 2.24
3 Cross-talk in the innate immune system: neutrophils instruct recruitment and activation of dendritic cells during microbial infection. J Immunol 2003 2.18
4 p47 GTPases regulate Toxoplasma gondii survival in activated macrophages. Infect Immun 2005 1.93
5 IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-alpha in host macrophages. J Immunol 2005 1.83
6 Screening for Toxoplasma gondii-regulated transcriptional responses in lipopolysaccharide-activated macrophages. Infect Immun 2006 1.67
7 Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control. PLoS Pathog 2011 1.67
8 Mouse neutrophils are professional antigen-presenting cells programmed to instruct Th1 and Th17 T-cell differentiation. Int Immunol 2011 1.58
9 TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite. J Immunol 2008 1.47
10 Toxoplasma gondii triggers myeloid differentiation factor 88-dependent IL-12 and chemokine ligand 2 (monocyte chemoattractant protein 1) responses using distinct parasite molecules and host receptors. J Immunol 2004 1.40
11 Dendritic cells expressing plasmacytoid marker PDCA-1 are Trojan horses during Toxoplasma gondii infection. J Immunol 2008 1.39
12 Understanding the multiple functions of Gr-1(+) cell subpopulations during microbial infection. Immunol Res 2008 1.30
13 Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's disease. PLoS One 2012 1.28
14 Toxoplasma gondii genotype determines MyD88-dependent signaling in infected macrophages. J Immunol 2006 1.26
15 Toxoplasma gondii triggers release of human and mouse neutrophil extracellular traps. Infect Immun 2011 1.25
16 Toxoplasma gondii interferes with lipopolysaccharide-induced mitogen-activated protein kinase activation by mechanisms distinct from endotoxin tolerance. J Immunol 2004 1.25
17 p38 MAPK autophosphorylation drives macrophage IL-12 production during intracellular infection. J Immunol 2005 1.24
18 Microbial antigen triggers rapid mobilization of TNF-alpha to the surface of mouse neutrophils transforming them into inducers of high-level dendritic cell TNF-alpha production. J Immunol 2005 1.24
19 STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection. Infect Immun 2004 1.23
20 Toxoplasma gondii prevents chromatin remodeling initiated by TLR-triggered macrophage activation. J Immunol 2009 1.22
21 Toxoplasma gondii triggers Gi-dependent PI 3-kinase signaling required for inhibition of host cell apoptosis. J Cell Sci 2006 1.19
22 Mechanism of entry determines the ability of Toxoplasma gondii to inhibit macrophage proinflammatory cytokine production. Infect Immun 2002 1.08
23 Insights into inflammatory bowel disease using Toxoplasma gondii as an infectious trigger. Immunol Cell Biol 2011 1.07
24 CD154 plays a central role in regulating dendritic cell activation during infections that induce Th1 or Th2 responses. J Immunol 2003 1.01
25 Mouse neutrophils require JNK2 MAPK for Toxoplasma gondii-induced IL-12p40 and CCL2/MCP-1 release. J Immunol 2007 0.96
26 Neutrophils cast extracellular traps in response to protozoan parasites. Front Immunol 2012 0.93
27 CD73-generated adenosine facilitates Toxoplasma gondii differentiation to long-lived tissue cysts in the central nervous system. Proc Natl Acad Sci U S A 2012 0.91
28 CXCR3-dependent CD4⁺ T cells are required to activate inflammatory monocytes for defense against intestinal infection. PLoS Pathog 2013 0.91
29 Toxoplasma gondii triggers phosphorylation and nuclear translocation of dendritic cell STAT1 while simultaneously blocking IFNγ-induced STAT1 transcriptional activity. PLoS One 2013 0.89
30 Toxoplasma gondii inhibits covalent modification of histone H3 at the IL-10 promoter in infected macrophages. PLoS One 2009 0.88
31 Apoptosis and the balance of homeostatic and pathologic responses to protozoan infection. Infect Immun 2003 0.86
32 Phosphoinositide-3-kinase-dependent, MyD88-independent induction of CC-type chemokines characterizes the macrophage response to Toxoplasma gondii strains with high virulence. Infect Immun 2007 0.86
33 CCR2 and CD44 promote inflammatory cell recruitment during fatty liver formation in a lithogenic diet fed mouse model. PLoS One 2013 0.84
34 Toxoplasma gondii inhibits toll-like receptor 4 ligand-induced mobilization of intracellular tumor necrosis factor alpha to the surface of mouse peritoneal neutrophils. Infect Immun 2006 0.83
35 Toxoplasma gondii inhibits mast cell degranulation by suppressing phospholipase Cγ-mediated Ca(2+) mobilization. Front Microbiol 2013 0.81
36 Interleukin-12 p40- and Fas ligand-dependent apoptotic pathways involving STAT-1 phosphorylation are triggered during infection with a virulent strain of Toxoplasma gondii. Infect Immun 2003 0.81
37 Absence of mitogen-activated protein kinase family member c-Jun N-terminal kinase-2 enhances resistance to Toxoplasma gondii. Exp Parasitol 2010 0.79
38 Trefoil factor 2 negatively regulates type 1 immunity against Toxoplasma gondii. J Immunol 2012 0.76