Published in PLoS One on September 15, 2011
Serotonin receptors and their role in the pathophysiology and therapy of irritable bowel syndrome. Tech Coloproctol (2014) 1.02
Neurogenic and myogenic properties of pan-colonic motor patterns and their spatiotemporal organization in rats. PLoS One (2013) 0.95
Prolonged inhibition of 5-HT₃ receptors by palonosetron results from surface receptor inhibition rather than inducing receptor internalization. Br J Pharmacol (2013) 0.93
Evidence for Ca(2+)-regulated ATP release in gastrointestinal stromal tumors. Exp Cell Res (2013) 0.78
Involvement of MAPKs and PLC pathways in modulation of pacemaking activity by So-Cheong-Ryong-Tang in interstitial cells of Cajal from murine small intestine. ScientificWorldJournal (2013) 0.77
5-Hydroxytryptamine (5-HT) cellular sequestration during chronic exposure delays 5-HT3 receptor resensitization due to its subsequent release. J Biol Chem (2014) 0.75
Depressive disorder and gastrointestinal dysfunction after myocardial infarct are associated with abnormal tryptophan-5-hydroxytryptamine metabolism in rats. PLoS One (2017) 0.75
Altered tryptophan hydroxylase 2 expression in enteric serotonergic nerves in Hirschsprung's-associated enterocolitis. World J Gastroenterol (2016) 0.75
Roles of interleukin-9 in the growth and cholecystokinin-induced intracellular calcium signaling of cultured interstitial cells of Cajal. PLoS One (2014) 0.75
Identification and functional characterisation of 5-HT4 receptor in sea cucumber Apostichopus japonicus (Selenka). Sci Rep (2017) 0.75
Depolarizing Effects of Daikenchuto on Interstitial Cells of Cajal from Mouse Small Intestine. Pharmacogn Mag (2017) 0.75
Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine. J Physiol (1994) 6.46
Requirement of c-kit for development of intestinal pacemaker system. Development (1992) 4.11
Guidelines on the irritable bowel syndrome: mechanisms and practical management. Gut (2007) 3.87
Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles. J Physiol (2009) 3.02
Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol (2009) 2.96
The 5-HT3B subunit is a major determinant of serotonin-receptor function. Nature (1999) 2.91
W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor. Genes Dev (1990) 2.77
Serotonin receptors. Chem Rev (2008) 2.43
Receptor-activated Ca2+ influx via human Trp3 stably expressed in human embryonic kidney (HEK)293 cells. Evidence for a non-capacitative Ca2+ entry. J Biol Chem (1998) 2.32
Smooth muscle cell calcium activation mechanisms. J Physiol (2008) 2.12
Development and plasticity of interstitial cells of Cajal. Neurogastroenterol Motil (1999) 2.09
Alterations in expression of p11 and SERT in mucosal biopsy specimens of patients with irritable bowel syndrome. Gastroenterology (2006) 1.91
Altered 5-hydroxytryptamine signaling in patients with constipation- and diarrhea-predominant irritable bowel syndrome. Gastroenterology (2006) 1.85
Relationship between the nerve action potential and transmitter release from sympathetic postganglionic nerve terminals. Nature (1987) 1.70
Rhythmic Cl- current and physiological roles of the intestinal c-kit-positive cells. Pflugers Arch (1995) 1.49
About the presence of interstitial cells of Cajal outside the musculature of the gastrointestinal tract. J Cell Mol Med (2005) 1.48
Mechanisms of Disease: specialized interstitial cells of the urinary tract--an assessment of current knowledge. Nat Clin Pract Urol (2005) 1.48
High-conductance chloride channels generate pacemaker currents in interstitial cells of Cajal. Gastroenterology (2002) 1.46
Characterization of the novel human serotonin receptor subunits 5-HT3C,5-HT3D, and 5-HT3E. Mol Pharmacol (2007) 1.42
Guide to the identification of interstitial cells of Cajal. Microsc Res Tech (1999) 1.36
Two types of spontaneous depolarizations in the interstitial cells freshly prepared from the murine small intestine. J Physiol (2004) 1.34
Ca2+ phase waves: a basis for cellular pacemaking and long-range synchronicity in the guinea-pig gastric pylorus. J Physiol (2003) 1.34
Tissue-specific mathematical models of slow wave entrainment in wild-type and 5-HT(2B) knockout mice with altered interstitial cells of Cajal networks. Biophys J (2010) 1.31
Voltage-dependent inward currents of interstitial cells of Cajal from murine colon and small intestine. J Physiol (2002) 1.30
Lack of serotonin 5-HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo. Neurogastroenterol Motil (2009) 1.26
Requirement of ryanodine receptors for pacemaker Ca2+ activity in ICC and HEK293 cells. J Cell Sci (2004) 1.26
Calcium oscillation linked to pacemaking of interstitial cells of Cajal: requirement of calcium influx and localization of TRP4 in caveolae. J Biol Chem (2002) 1.26
Molecular and functional characterization of ERG, KCNQ, and KCNE subtypes in rat stomach smooth muscle. Am J Physiol Gastrointest Liver Physiol (2002) 1.24
Exogenous serotonin regulates proliferation of interstitial cells of Cajal in mouse jejunum through 5-HT2B receptors. Gastroenterology (2007) 1.23
Pulse-driven magnetoimpedance sensor detection of biomagnetic fields in musculatures with spontaneous electric activity. Biosens Bioelectron (2011) 1.22
Generation and propagation of gastric slow waves. Clin Exp Pharmacol Physiol (2009) 1.21
Morphological and physiological evidence for interstitial cell of Cajal-like cells in the guinea pig gallbladder. J Physiol (2007) 1.20
Selective serotonin 5-HT3 receptor antagonists for postoperative nausea and vomiting: are they all the same? CNS Drugs (2005) 1.20
Simultaneous imaging of Ca2+ signals in interstitial cells of Cajal and longitudinal smooth muscle cells during rhythmic activity in mouse ileum. J Physiol (2002) 1.20
Gut pacemaker cells: the interstitial cells of Cajal (ICC). J Smooth Muscle Res (2003) 1.19
Characterization of a Ca2+ release-activated nonselective cation current regulating membrane potential and [Ca2+]i oscillations in transgenically derived beta-cells. J Biol Chem (1998) 1.18
Kit-like immunopositive cells in sheep mesenteric lymphatic vessels. Cell Tissue Res (2002) 1.18
Expression and function of 5-HT4 receptors in the mouse enteric nervous system. Am J Physiol Gastrointest Liver Physiol (2005) 1.14
Interstitial cells of Cajal are functionally innervated by excitatory motor neurones in the murine intestine. J Physiol (2004) 1.13
Recent advances in understanding the role of serotonin in gastrointestinal motility in functional bowel disorders: alterations in 5-HT signalling and metabolism in human disease. Neurogastroenterol Motil (2007) 1.12
Origins and distribution of cholinergically induced beta rhythms in hippocampal slices. J Neurosci (2000) 1.09
TRPC4 currents have properties similar to the pacemaker current in interstitial cells of Cajal. Am J Physiol Cell Physiol (2002) 1.07
Gastrointestinal peristalsis: joint action of enteric nerves, smooth muscle, and interstitial cells of Cajal. Microsc Res Tech (1999) 1.04
A 5-HT(4)-receptor activation-induced neural plasticity enhances in vivo reconstructs of enteric nerve circuit insult. Neurogastroenterol Motil (2010) 1.03
Pharmacology of serotonin: what a clinician should know. Gut (2004) 1.02
Chemotherapy-induced nausea and vomiting: current and new standards in the antiemetic prophylaxis and treatment. Eur J Cancer (2005) 1.01
Spontaneous electrical and Ca2+ signals in typical and atypical smooth muscle cells and interstitial cell of Cajal-like cells of mouse renal pelvis. J Physiol (2007) 1.00
A biophysically based mathematical model of unitary potential activity in interstitial cells of Cajal. Biophys J (2008) 0.99
Options for patients with irritable bowel syndrome: contrasting traditional and novel serotonergic therapies. Neurogastroenterol Motil (2004) 0.99
Pacemaker phase shift in the absence of neural activity in guinea-pig stomach: a microelectrode array study. J Physiol (2006) 0.98
Calcium-associated mechanisms in gut pacemaker activity. J Cell Mol Med (2007) 0.97
Involvement of ryanodine receptors in muscarinic receptor-mediated membrane current oscillation in urinary bladder smooth muscle. Am J Physiol Cell Physiol (2004) 0.92
Recent advances in studies of spontaneous activity in smooth muscle: ubiquitous pacemaker cells. Prog Biophys Mol Biol (2010) 0.91
5-HT and the brain-gut axis: opportunities for pharmacologic intervention. Expert Opin Investig Drugs (2007) 0.91
Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy. J Cancer Res Clin Oncol (2008) 0.89
In vitro enhanced differentiation of neural networks in ES gut-like organ from mouse ES cells by a 5-HT4-receptor activation. Biochem Biophys Res Commun (2011) 0.89
Sulphonylurea receptors differently modulate ICC pacemaker Ca2+ activity and smooth muscle contractility. J Cell Sci (2005) 0.88
Co-contribution of IP3R and Ca2+ influx pathways to pacemaker Ca2+ activity in stomach ICC. J Biol Rhythms (2005) 0.87
Microelectrode array evaluation of gut pacemaker activity in wild-type and W/W(v) mice. Biosens Bioelectron (2009) 0.87
Interstitial cells of Cajal in the gastrointestinal musculature of W mutant mice. Arch Histol Cytol (2007) 0.86
Sodium-, chloride-, and mibefradil-sensitive calcium channels in intestinal pacing in wild-type and W/WV mice. Can J Physiol Pharmacol (2006) 0.82
Spontaneous rhythmicity in cultured cell clusters isolated from mouse small intestine. Jpn J Physiol (2002) 0.82
Activation of intestinal smooth muscle cells by interstitial cells of Cajal in simulation studies. Am J Physiol Gastrointest Liver Physiol (2004) 0.81
Enteric nervous system disorders: genetic and molecular insights for the neurogastroenterologist. Neurogastroenterol Motil (2001) 0.78
Purinergic modulation of pacemaker Ca2+ activity in interstitial cells of Cajal. Neuropharmacology (2004) 0.78
Different modulation of spontaneous activities by nitrergic inhibitory nerves between ileum and jejunum in W/Wv mutant mice. Auton Neurosci (2005) 0.76
The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism. J Clin Invest (2005) 2.80
TRPV2 is a component of osmotically sensitive cation channels in murine aortic myocytes. Circ Res (2003) 2.08
Advanced glycation endproduct-induced calcium handling impairment in mouse cardiac myocytes. J Mol Cell Cardiol (2002) 1.86
Functional interaction between T2R taste receptors and G-protein alpha subunits expressed in taste receptor cells. J Neurosci (2003) 1.85
Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4. J Biol Chem (2002) 1.48
Anandamide induces apoptosis in human endothelial cells: its regulation system and clinical implications. Thromb Haemost (2003) 1.46
Delayed gastric emptying after pancreatoduodenectomy. J Surg Res (2011) 1.45
Participation of KCNQ (Kv7) potassium channels in myogenic control of cerebral arterial diameter. J Physiol (2010) 1.43
New tricks for old dogs: KCNQ expression and role in smooth muscle. Br J Pharmacol (2009) 1.32
Molecular basis of pimarane compounds as novel activators of large-conductance Ca(2+)-activated K(+) channel alpha-subunit. Mol Pharmacol (2002) 1.28
Requirement of ryanodine receptors for pacemaker Ca2+ activity in ICC and HEK293 cells. J Cell Sci (2004) 1.26
Calcium oscillation linked to pacemaking of interstitial cells of Cajal: requirement of calcium influx and localization of TRP4 in caveolae. J Biol Chem (2002) 1.26
Molecular and functional characterization of ERG, KCNQ, and KCNE subtypes in rat stomach smooth muscle. Am J Physiol Gastrointest Liver Physiol (2002) 1.24
Patterning of virus-infected Glycine max seed coat is associated with suppression of endogenous silencing of chalcone synthase genes. Plant Cell (2004) 1.22
A-type potassium currents in smooth muscle. Am J Physiol Cell Physiol (2003) 1.21
Pulse-driven magnetoimpedance sensor detection of cardiac magnetic activity. PLoS One (2011) 1.21
Comparison of the properties of CLCA1 generated currents and I(Cl(Ca)) in murine portal vein smooth muscle cells. J Physiol (2002) 1.14
Identification of autoantibodies against TRPM1 in patients with paraneoplastic retinopathy associated with ON bipolar cell dysfunction. PLoS One (2011) 1.12
Generation of a transgenic rabbit model of retinal degeneration. Invest Ophthalmol Vis Sci (2008) 1.11
Regulation of Kv4.3 currents by Ca2+/calmodulin-dependent protein kinase II. Am J Physiol Cell Physiol (2004) 1.11
The star-type color pattern in Petunia hybrida 'red Star' flowers is induced by sequence-specific degradation of chalcone synthase RNA. Plant Cell Physiol (2005) 1.10
Oncologic outcome of intersphincteric resection for very low rectal cancer. World J Surg (2009) 1.10
MyD88-dependent signals are essential for the host immune response in experimental brain abscess. J Immunol (2007) 1.10
Epithelial-mesenchymal transition and mesenchymal-epithelial transition via regulation of ZEB-1 and ZEB-2 expression in pancreatic cancer. J Surg Oncol (2011) 1.09
MyD88 expression by CNS-resident cells is pivotal for eliciting protective immunity in brain abscesses. ASN Neuro (2009) 1.09
Characterization of in vitro gutlike organ formed from mouse embryonic stem cells. Am J Physiol Cell Physiol (2004) 1.09
M2-polarized tumor-associated macrophage infiltration of regional lymph nodes is associated with nodal lymphangiogenesis and occult nodal involvement in pN0 pancreatic cancer. Pancreas (2013) 1.09
Membrane cholesterol but not putative receptors mediates anandamide-induced hepatocyte apoptosis. Hepatology (2003) 1.08
Rac is involved in the interkinetic nuclear migration of cortical progenitor cells. Neurosci Res (2009) 1.08
Clinical implication of ZEB-1 and E-cadherin expression in hepatocellular carcinoma (HCC). BMC Cancer (2013) 1.08
TLR2 expression in astrocytes is induced by TNF-alpha- and NF-kappa B-dependent pathways. J Immunol (2008) 1.07
Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladder smooth muscle. J Physiol (2007) 1.06
Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles. Am J Physiol Gastrointest Liver Physiol (2009) 1.05
Effectiveness of a transanal tube for the prevention of anastomotic leakage after rectal cancer surgery. World J Surg (2014) 1.04
Modified cardiovascular L-type channels in mice lacking the voltage-dependent Ca2+ channel beta3 subunit. J Biol Chem (2003) 1.03
Gamma-aminobutyric acid-containing sympathetic preganglionic neurons in rat thoracic spinal cord send their axons to the superior cervical ganglion. J Comp Neurol (2007) 1.02
TRIC-A channels in vascular smooth muscle contribute to blood pressure maintenance. Cell Metab (2011) 1.02
The unfolded protein response is activated in differentiating epidermal keratinocytes. J Invest Dermatol (2009) 1.01
Voltage-dependent Ca2+-channel block by openers of intermediate and small conductance Ca2+-activated K+ channels in urinary bladder smooth muscle cells. J Pharmacol Sci (2006) 1.00
Tobacco calmodulin-like protein provides secondary defense by binding to and directing degradation of virus RNA silencing suppressors. Proc Natl Acad Sci U S A (2012) 1.00
Cardioprotective effects of estradiol include the activation of large-conductance Ca(2+)-activated K(+) channels in cardiac mitochondria. Am J Physiol Heart Circ Physiol (2005) 1.00
Ca(2+) channel properties in smooth muscle cells of the urinary bladder from pig and human. Eur J Pharmacol (2002) 0.98
Pacemaker phase shift in the absence of neural activity in guinea-pig stomach: a microelectrode array study. J Physiol (2006) 0.98
Virus-mediated efficient induction of epigenetic modifications of endogenous genes with phenotypic changes in plants. Plant J (2010) 0.98
Functional interaction between KChIP1 and GFP-fused Kv4.3L co-expressed in HEK293 cells. Pflugers Arch (2002) 0.97
Calcium-associated mechanisms in gut pacemaker activity. J Cell Mol Med (2007) 0.97
Stoichiometry of Na+-Ca2+ exchange is 3:1 in guinea-pig ventricular myocytes. J Physiol (2002) 0.97
In vitro formation of enteric neural network structure in a gut-like organ differentiated from mouse embryonic stem cells. Stem Cells (2006) 0.96
Long-term outcomes after intersphincteric resection for low-lying rectal cancer. Ann Surg Oncol (2014) 0.96
Involvement of dominant-negative spliced variants of the intermediate conductance Ca2+-activated K+ channel, K(Ca)3.1, in immune function of lymphoid cells. J Biol Chem (2011) 0.93
Voltage-sensitive oxonol dyes are novel large-conductance Ca2+-activated K+ channel activators selective for beta1 and beta4 but not for beta2 subunits. Mol Pharmacol (2007) 0.93
Mechanism of leflunomide-induced proliferation of mitochondria in mammalian cells. Mitochondrion (2002) 0.93
Involvement of ryanodine receptors in muscarinic receptor-mediated membrane current oscillation in urinary bladder smooth muscle. Am J Physiol Cell Physiol (2004) 0.92
Two-step Ca2+ intracellular release underlies excitation-contraction coupling in mouse urinary bladder myocytes. Am J Physiol Cell Physiol (2005) 0.92
Effect of plasmin on laminin and fibronectin during plasmin-assisted vitrectomy. Arch Ophthalmol (2005) 0.92
Saturated salt solution method: a useful cadaver embalming for surgical skills training. Medicine (Baltimore) (2014) 0.92
Bladder-sparing extended resection of locally advanced rectal cancer involving the prostate and seminal vesicles. Surg Today (2007) 0.92
The synthetic peroxisome proliferator-activated receptor-gamma agonist ciglitazone attenuates neuroinflammation and accelerates encapsulation in bacterial brain abscesses. J Immunol (2008) 0.91
Pax6 transcription factor is required for the interkinetic nuclear movement of neuroepithelial cells. Genes Cells (2007) 0.91
Characterization of mammalian synemin, an intermediate filament protein present in all four classes of muscle cells and some neuroglial cells: co-localization and interaction with type III intermediate filament proteins and keratins. Cell Tissue Res (2003) 0.91
Recent advances in studies of spontaneous activity in smooth muscle: ubiquitous pacemaker cells. Prog Biophys Mol Biol (2010) 0.91
Phosphorylation of cytokeratin 17 by herpes simplex virus type 2 US3 protein kinase. Microbiol Immunol (2002) 0.90
CD133 expression in rectal cancer after preoperative chemoradiotherapy. Cancer Sci (2009) 0.88
Accelerated Ca2+ entry by membrane hyperpolarization due to Ca2+-activated K+ channel activation in response to histamine in chondrocytes. Am J Physiol Cell Physiol (2009) 0.88
Sulphonylurea receptors differently modulate ICC pacemaker Ca2+ activity and smooth muscle contractility. J Cell Sci (2005) 0.88
The large conductance potassium channel beta-subunit can interact with and modulate the functional properties of a calcium-activated chloride channel, CLCA1. J Biol Chem (2002) 0.87
Microelectrode array evaluation of gut pacemaker activity in wild-type and W/W(v) mice. Biosens Bioelectron (2009) 0.87
Dihydropyridine Ca2+ channel antagonists and agonists block Kv4.2, Kv4.3 and Kv1.4 K+ channels expressed in HEK293 cells. Br J Pharmacol (2003) 0.87
Ca2+-dependent modulation of intracellular Mg2+ concentration with amiloride and KB-R7943 in pig carotid artery. J Biol Chem (2003) 0.87
Co-contribution of IP3R and Ca2+ influx pathways to pacemaker Ca2+ activity in stomach ICC. J Biol Rhythms (2005) 0.87
Use of adipose tissue-derived stromal cells for prevention of esophageal stricture after circumferential EMR in a canine model. Gastrointest Endosc (2011) 0.86
Malignancy grade-dependent expression of K+-channel subtypes in human prostate cancer. J Pharmacol Sci (2009) 0.86
Inhibition of Kv1.3 potassium current by phosphoinositides and stromal-derived factor-1alpha in Jurkat T cells. Am J Physiol Cell Physiol (2009) 0.86
Apical and basolateral ATP-induced anion secretion in polarized human airway epithelia. Am J Respir Cell Mol Biol (2003) 0.86
Acupuncture modulates mechanical responses of smooth muscle produced by transmural nerve stimulation in gastric antrum of genetically hyperglycemic rats. J Smooth Muscle Res (2009) 0.86
Reduction of airway anion secretion via CFTR in sphingomyelin pathway. Biochem Biophys Res Commun (2004) 0.85
Molecular assembly and dynamics of fluorescent protein-tagged single KCa1.1 channel in expression system and vascular smooth muscle cells. Am J Physiol Cell Physiol (2012) 0.85
Physiological function of S-cone system is not enhanced in rd7 mice. Exp Eye Res (2005) 0.85
Antibiotic cyclic AMP signaling by "primed" leukocytes confers anti-inflammatory cytoprotection. J Leukoc Biol (2003) 0.85