W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor.

PubWeight™: 2.77‹?› | Rank: Top 1%

🔗 View Article (PMID 1692559)

Published in Genes Dev on March 01, 1990

Authors

A D Reith1, R Rottapel, E Giddens, C Brady, L Forrester, A Bernstein

Author Affiliations

1: Division of Molecular and Developmental Biology, Mount Sinai Hospital Research Institute, Toronto, Ontario, Canada.

Articles citing this

Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo. Am J Pathol (2005) 3.88

Long-term reconstitution of the mouse hematopoietic system by embryonic stem cell-derived fetal liver. Proc Natl Acad Sci U S A (1991) 2.66

Hematopoietic stem cell: self-renewal versus differentiation. Wiley Interdiscip Rev Syst Biol Med (2010) 2.38

A dominant negative mutation suppresses the function of normal epidermal growth factor receptors by heterodimerization. Mol Cell Biol (1991) 2.27

Interactions of phosphatidylinositol kinase, GTPase-activating protein (GAP), and GAP-associated proteins with the colony-stimulating factor 1 receptor. Mol Cell Biol (1990) 1.95

Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism. Proc Natl Acad Sci U S A (1991) 1.81

The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor. Mol Cell Biol (1991) 1.76

Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis. EMBO J (1991) 1.63

Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation. Proc Natl Acad Sci U S A (1991) 1.61

Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase. EMBO J (1991) 1.58

Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis. EMBO J (1998) 1.56

The c-kit receptor, stem cell factor, and mast cells. What each is teaching us about the others. Am J Pathol (1993) 1.55

Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool. Blood (2011) 1.54

The Wsh and Ph mutations affect the c-kit expression profile: c-kit misexpression in embryogenesis impairs melanogenesis in Wsh and Ph mutant mice. Proc Natl Acad Sci U S A (1995) 1.52

c-Kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas. Mol Biol Cell (1992) 1.50

A genetic screen for vascular mutants in zebrafish reveals dynamic roles for Vegf/Plcg1 signaling during artery development. Dev Biol (2009) 1.45

Exon skipping by mutation of an authentic splice site of c-kit gene in W/W mouse. Nucleic Acids Res (1991) 1.40

A specific combination of substrates is involved in signal transduction by the kit-encoded receptor. EMBO J (1991) 1.39

Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyrosine kinase in fibroblasts and interleukin 3-dependent hematopoietic cells. Mol Cell Biol (1993) 1.36

The immune response to herpes simplex virus type 1 infection in susceptible mice is a major cause of central nervous system pathology resulting in fatal encephalitis. J Virol (2008) 1.36

Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation. EMBO J (1999) 1.33

Dominant negative and loss of function mutations of the c-kit (mast/stem cell growth factor receptor) proto-oncogene in human piebaldism. Am J Hum Genet (1992) 1.27

Mouse platelet-derived growth factor receptor alpha gene is deleted in W19H and patch mutations on chromosome 5. Proc Natl Acad Sci U S A (1991) 1.17

Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase. Proc Natl Acad Sci U S A (1992) 1.17

Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants. Mol Cell Biol (1992) 1.14

Mutation discovery in the mouse using genetically guided array capture and resequencing. Mamm Genome (2009) 1.13

Human piebald trait resulting from a dominant negative mutant allele of the c-kit membrane receptor gene. J Clin Invest (1992) 1.12

Heterozygous kit mutants with little or no apparent anemia exhibit large defects in overall hematopoietic stem cell function. Exp Hematol (2007) 1.12

Oncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1. Proc Natl Acad Sci U S A (1996) 1.11

KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers. Gastroenterology (2015) 1.10

Bidirectional communication between oocytes and follicle cells: ensuring oocyte developmental competence. Can J Physiol Pharmacol (2010) 1.10

Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages. Proc Natl Acad Sci U S A (2004) 1.10

Do pluripotent stem cells exist in adult mice as very small embryonic stem cells? Stem Cell Reports (2013) 1.06

cKit+ cardiac progenitors of neural crest origin. Proc Natl Acad Sci U S A (2015) 1.06

Increased Kit/SCF receptor induced mitogenicity but abolished cell motility after inhibition of protein kinase C. EMBO J (1993) 1.05

Genetic analysis reveals cell type-specific regulation of receptor tyrosine kinase c-Kit by the protein tyrosine phosphatase SHP1. J Exp Med (1996) 1.04

Ovarian ageing, follicle depletion, and cancer: a hypothesis for the aetiology of epithelial ovarian cancer involving follicle depletion. Lancet Oncol (2008) 1.02

The self-incompatibility phenotype in brassica is altered by the transformation of a mutant S locus receptor kinase Plant Cell (1998) 1.02

Comparison of mechanical and electrical activity and interstitial cells of Cajal in urinary bladders from wild-type and W/Wv mice. Br J Pharmacol (2009) 1.01

Receptor functions and ligand-dependent transforming potential of a chimeric kit proto-oncogene. Mol Cell Biol (1990) 0.99

Cell type-specific deficiency of c-kit gene expression in mutant mice of mi/mi genotype. Am J Pathol (1994) 0.97

Spontaneous malignant transformation of melanocytes explanted from Wf/Wf mice with a Kit kinase-domain mutation. Proc Natl Acad Sci U S A (1992) 0.96

Deficient differentiation of mast cells in the skin of mi/mi mice. Usefulness of in situ hybridization for evaluation of mast cell phenotype. Am J Pathol (1993) 0.96

Allelic deletions in the long arm of chromosome 12 identify sites of candidate tumor suppressor genes in male germ cell tumors. Proc Natl Acad Sci U S A (1992) 0.95

Rump white inversion in the mouse disrupts dipeptidyl aminopeptidase-like protein 6 and causes dysregulation of Kit expression. Proc Natl Acad Sci U S A (1998) 0.94

Structural analysis of chromosomal rearrangements associated with the developmental mutations Ph, W19H, and Rw on mouse chromosome 5. Proc Natl Acad Sci U S A (1994) 0.94

The c-fms gene complements the mitogenic defect in mast cells derived from mutant W mice but not mi (microphthalmia) mice. Proc Natl Acad Sci U S A (1991) 0.93

Serotonin augments gut pacemaker activity via 5-HT3 receptors. PLoS One (2011) 0.92

Differentiation of zebrafish melanophores depends on transcription factors AP2 alpha and AP2 epsilon. PLoS Genet (2010) 0.90

PRL2/PTP4A2 phosphatase is important for hematopoietic stem cell self-renewal. Stem Cells (2014) 0.90

Role of the extracellular matrix in neural crest cell migration. J Anat (1997) 0.90

Spermatogonial stem cells derived from infertile Wv/Wv mice self-renew in vitro and generate progeny following transplantation. Biol Reprod (2009) 0.89

Azoospermia in mice with targeted disruption of the Brek/Lmtk2 (brain-enriched kinase/lemur tyrosine kinase 2) gene. Proc Natl Acad Sci U S A (2006) 0.89

Mast cells can contribute to axon-glial dissociation and fibrosis in peripheral nerve. Neuron Glia Biol (2007) 0.88

A reduction of cyclooxygenase 2 gene dosage counters the ovarian morphological aging and tumor phenotype in Wv mice. Am J Pathol (2007) 0.87

Expression of functional c-kit receptors rescues the genetic defect of W mutant mast cells. EMBO J (1991) 0.86

Human insulin-like growth factor I receptor function in pituitary cells is suppressed by a dominant negative mutant. J Clin Invest (1992) 0.84

Explicit targeting of transformed cells by VSV in ovarian epithelial tumor-bearing Wv mouse models. Gynecol Oncol (2009) 0.83

Inhibition of Gsk3β activity improves β-cell function in c-KitWv/+ male mice. Lab Invest (2012) 0.82

7,12-dimethylbenz[a]anthracene induces sertoli-leydig-cell tumors in the follicle-depleted ovaries of mice treated with 4-vinylcyclohexene diepoxide. Comp Med (2010) 0.82

Identification of a novel point mutation of mouse proto-oncogene c-kit through N-ethyl-N-nitrosourea mutagenesis. Genetics (2005) 0.82

White spotting variant mouse as an experimental model for ovarian aging and menopausal biology. Menopause (2012) 0.82

Mast cells in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis. Int J Mol Sci (2012) 0.82

Identification of hair shaft progenitors that create a niche for hair pigmentation. Genes Dev (2017) 0.82

Phosphatase of regenerating liver 2 (PRL2) deficiency impairs Kit signaling and spermatogenesis. J Biol Chem (2013) 0.81

The c-kit signaling pathway is involved in the development of persistent pain. Pain (2009) 0.80

Genetic interaction between Kit and Scl. Blood (2013) 0.80

Cyclooxygenase-1 inhibition prolongs postnatal ovarian follicle lifespan in mice. Biol Reprod (2013) 0.78

Phosphatidylinositol 3'-kinase associates with p145c-kit as part of a cell type characteristic multimeric signalling complex. EMBO J (1993) 0.78

Myogenic reprogramming of bone marrow derived cells in a W⁴¹Dmd(mdx) deficient mouse model. PLoS One (2011) 0.78

Global deletion of Trp53 reverts ovarian tumor phenotype of the germ cell-deficient white spotting variant (Wv) mice. Neoplasia (2015) 0.78

Oncolytic virotherapy for ovarian cancer. Oncolytic Virother (2012) 0.77

Identification of a unique membrane-bound molecule on a hemopoietic stem cell line and on multipotent progenitor cells. Proc Natl Acad Sci U S A (1995) 0.77

Follicle Depletion Provides a Permissive Environment for Ovarian Carcinogenesis. Mol Cell Biol (2016) 0.76

Genetics of the ovarian reserve. Front Genet (2015) 0.76

GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells. Front Immunol (2017) 0.75

Assessment of embryonic myocardial cell differentiation using a dual fluorescent reporter system. J Cell Mol Med (2008) 0.75

Effect of the c-kit codon 584 Phe----Leu substitution demonstrated in human piebaldism. Am J Hum Genet (1992) 0.75

Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury. Cell Death Dis (2016) 0.75

Mouse chromosome 5. Mamm Genome (1991) 0.75

VSV based virotherapy in ovarian cancer: the past, the present and …future? J Cancer (2017) 0.75

Identifying the niche controlling melanocyte differentiation. Genes Dev (2017) 0.75

Articles by these authors

A system to study promoter and terminator signals recognized by Escherichia coli RNA polymerase. Gene Amplif Anal (1981) 8.21

W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature (1995) 8.08

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/Wv mice. Cell (1985) 6.88

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature (1988) 6.35

The relationship between function and DNA sequence in an intercistronic regulatory region in phage lambda. Nature (1978) 5.38

Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: evidence from a phase III randomized trial. J Clin Oncol (2001) 4.09

A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell (1997) 3.65

Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1. Genes Dev (1991) 3.54

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice. Genes Dev (1989) 3.29

The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells. EMBO J (1995) 3.16

Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus. Nature (1985) 2.98

Stroke in users of low-dose oral contraceptives. N Engl J Med (1996) 2.98

Mice lacking both presenilin genes exhibit early embryonic patterning defects. Genes Dev (1999) 2.90

Phase III, multicenter, double-blind, randomized study of letrozole, an aromatase inhibitor, for advanced breast cancer versus megestrol acetate. J Clin Oncol (2001) 2.81

Sequence of Cro gene of bacteriophage lambda. Nature (1977) 2.78

Elevated serum Her-2/neu level predicts decreased response to hormone therapy in metastatic breast cancer. J Clin Oncol (2002) 2.70

Long-term reconstitution of the mouse hematopoietic system by embryonic stem cell-derived fetal liver. Proc Natl Acad Sci U S A (1991) 2.66

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling. Nature (1994) 2.63

Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia. Immunity (2000) 2.59

Fv2 encodes a truncated form of the Stk receptor tyrosine kinase. Nat Genet (1999) 2.48

Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3. Nature (1997) 2.46

High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene. Mol Cell Biol (1989) 2.45

Cell lineage-specific undermethylation of mouse repetitive DNA. Nature (1984) 2.43

A mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulators. EMBO J (1991) 2.38

Structure and function of the cy control region of bacteriophage lambda. J Mol Biol (1980) 2.37

Pleiotropic properties and genetic organization of the tolA,B locus of Escherichia coli K-12. J Bacteriol (1972) 2.27

Genetic ablation: targeted expression of a toxin gene causes microphthalmia in transgenic mice. Science (1987) 2.27

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor. Curr Biol (1998) 2.26

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes. Nature (1995) 2.22

Retrovirus transfer of a bacterial gene into mouse haematopoietic progenitor cells. Nature (1983) 2.20

Friend virus-induced erythroleukemia and the multistage nature of cancer. Cell (1991) 2.16

The Friend virus genome: evidence for the stable association of MuLV sequences and sequences involved in erythroleukemic transformation. Cell (1977) 2.12

Nebulised salbutamol with and without ipratropium bromide in acute airflow obstruction. Lancet (1989) 2.04

Receptor tyrosine kinases: genetic evidence for their role in Drosophila and mouse development. Trends Genet (1990) 2.01

SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors. Mol Cell Biol (1992) 2.00

Inactivation of the p53 oncogene by internal deletion or retroviral integration in erythroleukemic cell lines induced by Friend leukemia virus. Oncogene (1988) 1.96

Retrovirus transduction: segregation of the viral transforming function and the herpes simplex virus tk gene in infectious Friend spleen focus-forming virus thymidine kinase vectors. Mol Cell Biol (1983) 1.94

p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci U S A (1993) 1.93

Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1. Nat Cell Biol (2000) 1.92

Modulation of gene expression in multiple hematopoietic cell lineages following retroviral vector gene transfer. Proc Natl Acad Sci U S A (1987) 1.86

A point mutation in CD28 distinguishes proliferative signals from survival signals. Nat Immunol (2001) 1.85

The Fas counterattack in vivo: apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma. J Immunol (1998) 1.78

Developmental origin and Kit-dependent development of the interstitial cells of cajal in the mammalian small intestine. Dev Dyn (1998) 1.78

The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor. Mol Cell Biol (1991) 1.76

Transformation-defective mutants of avian sarcoma viruses: the genetic relationship between conditional and nonconditional mutants. Virology (1976) 1.75

Expression of Fas ligand by human gastric adenocarcinomas: a potential mechanism of immune escape in stomach cancer. Gut (1999) 1.75

Retrovirus transduction: generation of infectious retroviruses expressing dominant and selectable genes is associated with in vivo recombination and deletion events. Mol Cell Biol (1983) 1.72

Serum HER-2/neu and response to the aromatase inhibitor letrozole versus tamoxifen. J Clin Oncol (2003) 1.72

Retroviral insertions downstream of the heterogeneous nuclear ribonucleoprotein A1 gene in erythroleukemia cells: evidence that A1 is not essential for cell growth. Mol Cell Biol (1992) 1.70

Deletion of 5'-coding sequences of the cellular p53 gene in mouse erythroleukemia: a novel mechanism of oncogene regulation. Mol Cell Biol (1987) 1.69

Methylation patterns of repetitive DNA sequences in germ cells of Mus musculus. Nucleic Acids Res (1984) 1.68

Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virus. Proc Natl Acad Sci U S A (1990) 1.67

Management of spontaneous pneumothorax using a Heimlich flutter valve. Thorax (1973) 1.66

Stroke and cocaine or amphetamine use. Epidemiology (1998) 1.62

Use of home health services: some findings from the National Medical Care Expenditure Survey. Home Health Care Serv Q (1985) 1.61

Retrovirus long terminal repeats activate expression of coding sequences for the herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci U S A (1982) 1.61

Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation. J Biol Chem (2000) 1.58

Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase. EMBO J (1991) 1.58

A long-term prospective assessment of home nebulizer treatment. Respir Med (1992) 1.57

v-erbA cooperates with sarcoma oncogenes in leukemic cell transformation. Cell (1986) 1.56

Each domain of the N-ethylmaleimide-sensitive fusion protein contributes to its transport activity. J Biol Chem (1995) 1.53

Control of transcription termination: a rho-dependent termination site in bacteriophage lambda. J Mol Biol (1980) 1.51

A mammalian dual specificity protein kinase, Nek1, is related to the NIMA cell cycle regulator and highly expressed in meiotic germ cells. EMBO J (1992) 1.49

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice. Nat Genet (1995) 1.49

Gene targeting with retroviral vectors: recombination by gene conversion into regions of nonhomology. Mol Cell Biol (1989) 1.48

Clonal analysis of early and late stages of erythroleukemia induced by molecular clones of integrated spleen focus-forming virus. Proc Natl Acad Sci U S A (1981) 1.46

Update on adolescent health care in pediatric practice. J Adolesc Health (1996) 1.45

Relationship between asthma and gastro-oesophageal reflux. Thorax (1981) 1.45

Simple point-of-care risk stratification in acute coronary syndromes: the AMIS model. Heart (2008) 1.45

Expression of human adenosine deaminase in murine haematopoietic progenitor cells following retroviral transfer. Nature (1986) 1.44

The c-kit receptor ligand functions as a mast cell chemoattractant. Blood (1992) 1.42

Retrovirus vectors containing an internal attachment site: evidence that circles are not intermediates to murine retrovirus integration. J Virol (1989) 1.42

SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain. Mol Cell Biol (1998) 1.41

An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes. Mol Cell Biol (1995) 1.40

Generation of a novel Fli-1 protein by gene targeting leads to a defect in thymus development and a delay in Friend virus-induced erythroleukemia. Mol Cell Biol (1996) 1.38

Erythroleukemia induction by replication-competent type C viruses cloned from the anemia- and polycythemia-inducing isolates of Friend leukemia virus. J Exp Med (1980) 1.38

Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene. Mol Cell Biol (2001) 1.38

Quantitative colony method for tumorigenic cells transformed by two distinct strains of Friend leukemia virus. Proc Natl Acad Sci U S A (1981) 1.35

Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development. Development (1999) 1.33

Misuse of pressurised nebulisers. Br Med J (1978) 1.33

Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation. EMBO J (1999) 1.33

Contiguous patterns of c-kit and steel expression: analysis of mutations at the W and Sl loci. Development (1991) 1.33

Multistage Friend erythroleukemia: independent origin of tumor clones with normal or rearranged p53 cellular oncogenes. J Virol (1987) 1.32

The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor. Oncogene (1993) 1.32

Signalling by the W/Kit receptor tyrosine kinase is negatively regulated in vivo by the protein tyrosine phosphatase Shp1. Nat Genet (1996) 1.31

Anemia- and polycythemia-inducing isolates of Friend spleen focus-forming virus. Biological and molecular evidence for two distinct viral genomes. J Exp Med (1980) 1.29

Loss of a highly conserved domain on p53 as a result of gene deletion during Friend virus-induced erythroleukemia. Oncogene (1988) 1.28

The Fli-1 proto-oncogene, involved in erythroleukemia and Ewing's sarcoma, encodes a transcriptional activator with DNA-binding specificities distinct from other Ets family members. Oncogene (1993) 1.27

Molecular identification of a human DNA repair gene following DNA-mediated gene transfer. Nature (1984) 1.27

Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation. Immunity (1998) 1.25

The murine W/c-kit and Steel loci and the control of hematopoiesis. Semin Hematol (1991) 1.25

Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53 deficient mice. Oncogene (1994) 1.24

The Fps/Fes protein-tyrosine kinase promotes angiogenesis in transgenic mice. Mol Cell Biol (1994) 1.21

Genetic ablation in transgenic mice with an attenuated diphtheria toxin A gene. Mol Cell Biol (1990) 1.20

An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proc Natl Acad Sci U S A (1996) 1.18

Incidence of stroke and myocardial infarction in women of reproductive age. Stroke (1997) 1.17

Deregulated inflammatory response in mice lacking the STK/RON receptor tyrosine kinase. Genes Funct (1997) 1.17

Altered gait profile in subjects with peripheral arterial disease. Vasc Med (2001) 1.16