Published in J Biol Chem on September 28, 2011
Cell signaling, post-translational protein modifications and NMR spectroscopy. J Biomol NMR (2012) 1.06
Distinct functions for Rap1 signaling in vascular morphogenesis and dysfunction. Exp Cell Res (2013) 0.89
Integrin β3 crosstalk with VEGFR accommodating tyrosine phosphorylation as a regulatory switch. PLoS One (2012) 0.89
Site-specific NMR mapping and time-resolved monitoring of serine and threonine phosphorylation in reconstituted kinase reactions and mammalian cell extracts. Nat Protoc (2013) 0.87
Resistance to the mTOR-inhibitor RAD001 elevates integrin α2- and β1-triggered motility, migration and invasion of prostate cancer cells. Br J Cancer (2012) 0.87
β1 integrin NPXY motifs regulate kidney collecting-duct development and maintenance by induced-fit interactions with cytosolic proteins. Mol Cell Biol (2012) 0.82
Integrin αIIb-mediated PI3K/Akt activation in platelets. PLoS One (2012) 0.82
Nanodiscs and Solution NMR: preparation, application and challenges. Nanotechnol Rev (2016) 0.77
Phospho-Tyrosine(s) vs. Phosphatidylinositol Binding in Shc Mediated Integrin Signaling. Am J Mol Biol (2015) 0.77
Targeting Integrin-Dependent Adhesion and Signaling with 3-Arylquinoline and 3-Aryl-2-Quinolone Derivatives: A new Class of Integrin Antagonists. PLoS One (2015) 0.75
Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr (1998) 169.28
UCSF Chimera--a visualization system for exploratory research and analysis. J Comput Chem (2004) 112.47
NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J Biomol NMR (1995) 93.94
Integrins: bidirectional, allosteric signaling machines. Cell (2002) 36.25
Integrins: a family of cell surface receptors. Cell (1987) 21.14
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell (2006) 20.92
TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts. J Biomol NMR (2009) 16.09
The CCPN data model for NMR spectroscopy: development of a software pipeline. Proteins (2005) 13.03
Automated NMR structure calculation with CYANA. Methods Mol Biol (2004) 9.31
Refinement of protein structures in explicit solvent. Proteins (2003) 5.31
A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face. Cell (2002) 4.57
Structural basis for control by phosphorylation. Chem Rev (2001) 3.53
Efficient analysis of macromolecular rotational diffusion from heteronuclear relaxation data. J Biomol NMR (2000) 3.06
The structure of an integrin/talin complex reveals the basis of inside-out signal transduction. EMBO J (2009) 2.76
The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling. EMBO J (2009) 2.45
NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution. Biochemistry (2001) 1.76
Spin labeling of proteins. Methods Enzymol (1989) 1.75
Oligomerization of the integrin alphaIIbbeta3: roles of the transmembrane and cytoplasmic domains. Proc Natl Acad Sci U S A (2001) 1.74
Conversion of phosphorylase b to phosphorylase a in muscle extracts. J Biol Chem (1955) 1.74
Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation. Proc Natl Acad Sci U S A (2009) 1.71
Membrane-mediated structural transitions at the cytoplasmic face during integrin activation. Proc Natl Acad Sci U S A (2004) 1.66
Membrane protein-lipid interactions in mixed micelles studied by NMR spectroscopy with the use of paramagnetic reagents. Chembiochem (2004) 1.62
A structural basis for integrin activation by the cytoplasmic tail of the alpha IIb-subunit. Proc Natl Acad Sci U S A (2000) 1.49
Beta integrin tyrosine phosphorylation is a conserved mechanism for regulating talin-induced integrin activation. J Biol Chem (2009) 1.40
Integrin tyrosine phosphorylation in platelet signaling. Curr Opin Cell Biol (2001) 1.27
Characterization of the monomeric form of the transmembrane and cytoplasmic domains of the integrin beta 3 subunit by NMR spectroscopy. Biochemistry (2002) 1.18
NMR analysis of the alphaIIb beta3 cytoplasmic interaction suggests a mechanism for integrin regulation. Proc Natl Acad Sci U S A (2010) 1.16
Structural insight into the interaction between platelet integrin alphaIIbbeta3 and cytoskeletal protein skelemin. J Biol Chem (2007) 0.91
Protein-protein interactions probed by nuclear magnetic resonance spectroscopy. Methods Enzymol (2001) 0.91
Integrin {beta}3 phosphorylation dictates its complex with the Shc phosphotyrosine-binding (PTB) domain. J Biol Chem (2010) 0.91
Role of smooth muscle cells in the initiation and early progression of atherosclerosis. Arterioscler Thromb Vasc Biol (2008) 3.79
Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI. Nat Cell Biol (2002) 3.50
In vivo dynamics of Rac-membrane interactions. Mol Biol Cell (2006) 1.95
Inhibitor of differentiation-3 mediates high fat diet-induced visceral fat expansion. Arterioscler Thromb Vasc Biol (2011) 1.54
Integrin bidirectional signaling: a molecular view. PLoS Biol (2004) 1.49
Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility. Mol Cell (2005) 1.37
The integrin co-activator Kindlin-3 is expressed and functional in a non-hematopoietic cell, the endothelial cell. J Biol Chem (2010) 1.37
Regulation of integrin alphaIIbbeta3 activation by distinct regions of its cytoplasmic tails. Biochemistry (2006) 1.36
Kindling the flame of integrin activation and function with kindlins. Curr Opin Hematol (2009) 1.30
The integrin coactivator kindlin-2 plays a critical role in angiogenesis in mice and zebrafish. Blood (2011) 1.14
On the influence of the C2-O2 and C3-O3 bonds in 4,6-O-benzylidene-directed beta-mannopyranosylation and alpha-glucopyranosylation. J Org Chem (2006) 1.12
Tyrosine phosphorylation of integrin beta3 regulates kindlin-2 binding and integrin activation. J Biol Chem (2010) 1.10
Structural and functional insights into PINCH LIM4 domain-mediated integrin signaling. Nat Struct Biol (2003) 1.08
Id3 is a novel atheroprotective factor containing a functionally significant single-nucleotide polymorphism associated with intima-media thickness in humans. Circ Res (2010) 1.07
Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes. FEBS Lett (2005) 1.05
The helix-loop-helix factors Id3 and E47 are novel regulators of adiponectin. Circ Res (2008) 1.04
Synthesis of the antigenic tetrasaccharide side chain from the major glycoprotein of Bacillus anthracis exosporium. J Org Chem (2007) 0.96
State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association. Circ Res (2015) 0.94
Structural insight into the interaction between platelet integrin alphaIIbbeta3 and cytoskeletal protein skelemin. J Biol Chem (2007) 0.91
Integrin {beta}3 phosphorylation dictates its complex with the Shc phosphotyrosine-binding (PTB) domain. J Biol Chem (2010) 0.91
Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1. J Cell Biochem (2008) 0.90
Phase II trial of GM-CSF + thalidomide in patients with androgen-independent metastatic prostate cancer. Urol Oncol (2005) 0.89
Synthesis and glycosylation of a series of 6-mono-, di-, and trifluoro S-phenyl 2,3,4-tri-O-benzyl-thiorhamnopyranosides. Effect of the fluorine substituents on glycosylation stereoselectivity. J Am Chem Soc (2007) 0.89
Integrin β3 crosstalk with VEGFR accommodating tyrosine phosphorylation as a regulatory switch. PLoS One (2012) 0.89
Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environments. Biochem Biophys Res Commun (2009) 0.86
Facile oxidative cleavage of 4-O-benzyl ethers with dichlorodicyanoquinone in rhamno- and mannopyranosides. J Org Chem (2007) 0.85
NMR solution structure of human cannabinoid receptor-1 helix 7/8 peptide: candidate electrostatic interactions and microdomain formation. Biochem Biophys Res Commun (2009) 0.84
Optimization of the design and preparation of nanoscale phospholipid bilayers for its application to solution NMR. Proteins (2013) 0.83
Characterization of the neuron-specific L1-CAM cytoplasmic tail: naturally disordered in solution it exercises different binding modes for different adaptor proteins. Biochemistry (2008) 0.82
The solution structure of Bacillus anthracis dihydrofolate reductase yields insight into the analysis of structure-activity relationships for novel inhibitors. Biochemistry (2009) 0.81
Contribution of social isolation, restraint, and hindlimb unloading to changes in hemodynamic parameters and motion activity in rats. PLoS One (2012) 0.79
Structural insights into the recognition of β3 integrin cytoplasmic tail by the SH3 domain of Src kinase. Protein Sci (2013) 0.78
Structural studies of a signal peptide in complex with signal peptidase I cytoplasmic domain: the stabilizing effect of membrane-mimetics on the acquired fold. Proteins (2011) 0.77
Increased 12/15-lipoxygenase enhances cell growth, fibronectin deposition, and neointimal formation in response to carotid injury. Arterioscler Thromb Vasc Biol (2010) 0.77
Skelemin association with αIIbβ3 integrin: a structural model. Biochemistry (2014) 0.75
CD40/TRAF6 switch in neointimal hyperplasia. Blood (2008) 0.75
NMR structural characterization of the penta-peptide calpain inhibitor. FEBS Lett (2008) 0.75