Published in Crit Care Med on March 01, 2012
Two decades of mortality trends among patients with severe sepsis: a comparative meta-analysis*. Crit Care Med (2014) 3.82
Severe sepsis in pre-hospital emergency care: analysis of incidence, care, and outcome. Am J Respir Crit Care Med (2012) 3.36
Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study. Lancet Respir Med (2014) 3.02
Severe sepsis cohorts derived from claims-based strategies appear to be biased toward a more severely ill patient population. Crit Care Med (2013) 2.48
Heart failure–associated hospitalizations in the United States. J Am Coll Cardiol (2013) 2.44
Trends in bronchiolitis hospitalizations in the United States, 2000-2009. Pediatrics (2013) 2.14
Regulatory mandates for sepsis care--reasons for caution. N Engl J Med (2014) 2.11
Sepsis: multiple abnormalities, heterogeneous responses, and evolving understanding. Physiol Rev (2013) 1.72
Host innate immune responses to sepsis. Virulence (2013) 1.66
Hospital Incidence and Mortality Rates of Sepsis. Dtsch Arztebl Int (2016) 1.65
Impact of Policies on the Rise in Sepsis Incidence, 2000-2010. Clin Infect Dis (2016) 1.52
Comparison of trends in sepsis incidence and coding using administrative claims versus objective clinical data. Clin Infect Dis (2014) 1.51
The temporal kinetics of circulating angiopoietin levels in children with sepsis. Pediatr Crit Care Med (2014) 1.50
Early and late unplanned rehospitalizations for survivors of critical illness*. Crit Care Med (2015) 1.43
Improving documentation and coding for acute organ dysfunction biases estimates of changing sepsis severity and burden: a retrospective study. Crit Care (2015) 1.41
Variation in the Contents of Sepsis Bundles and Quality Measures. A Systematic Review. Ann Am Thorac Soc (2015) 1.40
Hospital-based acute care use in survivors of septic shock. Crit Care Med (2015) 1.34
Utilization patterns and outcomes associated with central venous catheter in septic shock: a population-based study. Crit Care Med (2013) 1.34
Persistent lymphopenia after diagnosis of sepsis predicts mortality. Shock (2014) 1.30
Molecular diagnosis of sepsis: New aspects and recent developments. Eur J Microbiol Immunol (Bp) (2014) 1.30
Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care. Crit Care (2013) 1.29
Rehospitalizations Following Sepsis: Common and Costly. Crit Care Med (2015) 1.23
Sepsis-related deaths in Brazil: an analysis of the national mortality registry from 2002 to 2010. Crit Care (2014) 1.22
Pathophysiologic mechanisms in septic shock. Lab Invest (2013) 1.19
Epidemiology and outcomes of acute respiratory failure in the United States, 2001 to 2009: a national survey. J Hosp Med (2013) 1.13
Systemic inflammatory response syndrome (SIRS): where did it come from and is it still relevant today? Virulence (2013) 1.10
Hospital readmission and healthcare utilization following sepsis in community settings. J Hosp Med (2014) 1.06
qSOFA, SIRS, and Early Warning Scores for Detecting Clinical Deterioration in Infected Patients Outside the ICU. Am J Respir Crit Care Med (2016) 1.03
Temporal trends in emergency department visits for bronchiolitis in the United States, 2006 to 2010. Pediatr Infect Dis J (2014) 1.03
Effect of Cholecalciferol Supplementation on Vitamin D Status and Cathelicidin Levels in Sepsis: A Randomized, Placebo-Controlled Trial. Crit Care Med (2015) 0.99
Contemporary trends of the epidemiology, clinical characteristics, and resource utilization of necrotizing fasciitis in Texas: a population-based cohort study. Crit Care Res Pract (2015) 0.98
Prediction of outcome from community-acquired severe sepsis and septic shock in tertiary-care university hospital in a developing country. Crit Care Res Pract (2012) 0.98
Intestine-Derived Matrix Metalloproteinase-8 Is a Critical Mediator of Polymicrobial Peritonitis. Crit Care Med (2016) 0.94
Evaluation of vitamin C for adjuvant sepsis therapy. Antioxid Redox Signal (2013) 0.94
Sepsis in old age: review of human and animal studies. Aging Dis (2014) 0.93
Ascorbate-dependent vasopressor synthesis: a rationale for vitamin C administration in severe sepsis and septic shock? Crit Care (2015) 0.93
Quantifying the improvement in sepsis diagnosis, documentation, and coding: the marginal causal effect of year of hospitalization on sepsis diagnosis. Ann Epidemiol (2015) 0.90
Epidemiology and recent trends of severe sepsis in Spain: a nationwide population-based analysis (2006-2011). BMC Infect Dis (2014) 0.90
Identifying Patients with Sepsis on the Hospital Wards. Chest (2016) 0.90
Childhood asthma hospitalizations in the United States, 2000-2009. J Pediatr (2013) 0.88
Acute Cholecystitis. Viszeralmedizin (2015) 0.87
Biomarkers for Sepsis: What Is and What Might Be? Biomark Insights (2015) 0.87
Propofol increases morbidity and mortality in a rat model of sepsis. Crit Care (2015) 0.87
Hospital costs and inpatient mortality among children undergoing surgery for congenital heart disease. Health Serv Res (2013) 0.86
Objective Sepsis Surveillance Using Electronic Clinical Data. Infect Control Hosp Epidemiol (2015) 0.86
Risk stratification and prognostic performance of the predisposition, infection, response, and organ dysfunction (PIRO) scoring system in septic patients in the emergency department: a cohort study. Crit Care (2014) 0.86
HDL in sepsis - risk factor and therapeutic approach. Front Pharmacol (2015) 0.85
Are there new approaches for diagnosis, therapy guidance and outcome prediction of sepsis? World J Exp Med (2015) 0.85
Epidemiology and Outcome of Severe Sepsis and Septic Shock in Surgical Intensive Care Units in Northern Taiwan. Medicine (Baltimore) (2015) 0.85
Hyperlactatemia affects the association of hyperglycemia with mortality in nondiabetic adults with sepsis. Acad Emerg Med (2012) 0.85
Increased FGF21 plasma levels in humans with sepsis and SIRS. Endocr Connect (2013) 0.84
Human metabolic response to systemic inflammation: assessment of the concordance between experimental endotoxemia and clinical cases of sepsis/SIRS. Crit Care (2015) 0.84
Acute-Phase Deaths from Murine Polymicrobial Sepsis Are Characterized by Innate Immune Suppression Rather Than Exhaustion. J Immunol (2015) 0.84
Pathophysiology of sepsis-related cardiac dysfunction: driven by inflammation, energy mismanagement, or both? Curr Heart Fail Rep (2015) 0.84
Functional outcomes of general medical patients with severe sepsis. BMC Infect Dis (2013) 0.83
Prognostic Implications of Serum Lipid Metabolism over Time during Sepsis. Biomed Res Int (2015) 0.83
Evolving trends in the epidemiology, resource utilization, and outcomes of pregnancy-associated severe sepsis: a population-based cohort study. J Clin Med Res (2015) 0.83
Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B. J Med Chem (2016) 0.82
Formal modelling of toll like receptor 4 and JAK/STAT signalling pathways: insight into the roles of SOCS-1, interferon-β and proinflammatory cytokines in sepsis. PLoS One (2014) 0.82
The Nociceptin/Orphanin FQ system is modulated in patients admitted to ICU with sepsis and after cardiopulmonary bypass. PLoS One (2013) 0.82
Mesenchymal stem cells as a therapeutic tool to treat sepsis. World J Stem Cells (2015) 0.82
Xuebijing Injection Promotes M2 Polarization of Macrophages and Improves Survival Rate in Septic Mice. Evid Based Complement Alternat Med (2015) 0.82
National Lupus Hospitalization Trends Reveal Rising Rates of Herpes Zoster and Declines in Pneumocystis Pneumonia. PLoS One (2016) 0.81
Sepsis surveillance from administrative data in the absence of a perfect verification. Ann Epidemiol (2016) 0.80
Activation of Hepatic STAT3 Maintains Pulmonary Defense during Endotoxemia. Infect Immun (2015) 0.80
Current challenges in understanding immune cell functions during septic syndromes. BMC Immunol (2015) 0.80
HMGB1 mediates anemia of inflammation in murine sepsis survivors. Mol Med (2015) 0.80
Early goal-directed resuscitation for patients with severe sepsis and septic shock: a meta-analysis and trial sequential analysis. Scand J Trauma Resusc Emerg Med (2016) 0.79
Voluntary wheel running attenuates lipopolysaccharide-induced liver inflammation in mice. Am J Physiol Regul Integr Comp Physiol (2016) 0.79
Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes. JCI Insight (2016) 0.79
Myeloid-derived suppressor cells in sepsis. Biomed Res Int (2014) 0.79
The CD14 rs2569190 TT Genotype Is Associated with an Improved 30-Day Survival in Patients with Sepsis: A Prospective Observational Cohort Study. PLoS One (2015) 0.79
Sepsis outcomes in patients receiving statins prior to hospitalization for sepsis: comparison of in-hospital mortality rates between patients who received atorvastatin and those who received simvastatin. Ann Intensive Care (2015) 0.79
Chronic kidney disease is associated with a higher 90-day mortality than other chronic medical conditions in patients with sepsis. Sci Rep (2015) 0.79
Sepsis in Canadian children: a national analysis using administrative data. Clin Epidemiol (2014) 0.79
The association between time to antibiotics and relevant clinical outcomes in emergency department patients with various stages of sepsis: a prospective multi-center study. Crit Care (2015) 0.79
A widened pulse pressure: a potential valuable prognostic indicator of mortality in patients with sepsis. J Community Hosp Intern Med Perspect (2015) 0.78
Nonhematopoietic Peroxisome Proliferator-Activated Receptor-α Protects Against Cardiac Injury and Enhances Survival in Experimental Polymicrobial Sepsis. Crit Care Med (2016) 0.78
Comparison of outcomes from sepsis between patients with and without pre-existing left ventricular dysfunction: a case-control analysis. Crit Care (2014) 0.78
Mortality predictors in renal transplant recipients with severe sepsis and septic shock. PLoS One (2014) 0.78
PIRO concept: Staging of sepsis. J Postgrad Med (2015) 0.78
Microbial Recognition and Danger Signals in Sepsis and Trauma. Biochim Biophys Acta (2017) 0.78
Mobilization in severe sepsis: an integrative review. J Hosp Med (2015) 0.77
Effect of early goal-directed therapy on mortality in patients with severe sepsis or septic shock: a meta-analysis of randomised controlled trials. BMJ Open (2016) 0.77
Current knowledge and future directions of TLR and NOD signaling in sepsis. Mil Med Res (2015) 0.77
Lysosome and Cytoskeleton Pathways Are Robustly Enriched in the Blood of Septic Patients: A Meta-Analysis of Transcriptomic Data. Mediators Inflamm (2015) 0.77
Chromogranin A levels and mortality in patients with severe sepsis. Biomarkers (2015) 0.77
Patterns of the Demographics, Clinical Characteristics, and Resource Utilization Among Maternal Decedents in Texas, 2001 - 2010: A Population-Based Cohort Study. J Clin Med Res (2015) 0.77
Risk Stratification and Prognosis in Sepsis: What Have We Learned from Microarrays? Clin Chest Med (2016) 0.76
Contemporary Trends of Reported Sepsis Among Maternal Decedents in Texas: A Population-Based Study. Infect Dis Ther (2015) 0.76
Clinical and Experimental Sepsis Impairs CD8 T-Cell-Mediated Immunity. Crit Rev Immunol (2016) 0.76
Role of the IL-33-ST2 axis in sepsis. Mil Med Res (2017) 0.76
Overview of progresses in critical care medicine 2012. J Thorac Dis (2013) 0.76
Milk fat globule-epidermal growth factor-factor VIII downregulates interleukin-17 expression in sepsis by modulating STAT3 activation. Surgery (2015) 0.76
Hypercapnia: is it protective in lung injury? Med Gas Res (2013) 0.76
Increased coagulation and suppressed generation of activated protein C in aged mice during intra-abdominal sepsis. Am J Physiol Heart Circ Physiol (2014) 0.76
Use of Systematic Methods to Improve Disease Identification in Administrative Data: The Case of Severe Sepsis. Med Care (2014) 0.75
Endotoxaemia-augmented murine venous thrombosis is dependent on TLR-4 and ICAM-1, and potentiated by neutropenia. Thromb Haemost (2016) 0.75
Public reporting and pay for performance in hospital quality improvement. N Engl J Med (2007) 10.55
Outcomes of care by hospitalists, general internists, and family physicians. N Engl J Med (2007) 6.51
Association of diagnostic coding with trends in hospitalizations and mortality of patients with pneumonia, 2003-2009. JAMA (2012) 5.95
Association between the choice of IV crystalloid and in-hospital mortality among critically ill adults with sepsis*. Crit Care Med (2014) 5.89
Antibiotic therapy and treatment failure in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease. JAMA (2010) 4.57
Comparative Effectiveness of Noninvasive and Invasive Ventilation in Critically Ill Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Crit Care Med (2015) 3.37
Shop for quality or volume? Volume, quality, and outcomes of coronary artery bypass surgery. Ann Intern Med (2009) 2.67
Patients' evaluations of health care providers in the era of social networking: an analysis of physician-rating websites. J Gen Intern Med (2010) 2.60
Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes. Crit Care Med (2011) 2.55
Perioperative use of selective serotonin reuptake inhibitors and risks for adverse outcomes of surgery. JAMA Intern Med (2013) 2.38
Missed opportunities for osteoporosis treatment in patients hospitalized for hip fracture. J Am Geriatr Soc (2010) 2.32
Potentially inappropriate medication use in hospitalized elders. J Hosp Med (2008) 2.17
Association between antibiotic treatment and outcomes in patients hospitalized with acute exacerbation of COPD treated with systemic steroids. Chest (2013) 2.12
Is statin use associated with reduced mortality after pneumonia? A systematic review and meta-analysis. Am J Med (2012) 2.09
Prevalence, treatment, and outcomes associated with OSA among patients hospitalized with pneumonia. Chest (2014) 2.09
Access to subspecialty care for patients with mobility impairment: a survey. Ann Intern Med (2013) 2.03
Choosing the best hospital: the limitations of public quality reporting. Health Aff (Millwood) (2008) 1.95
The influence of procedure volumes and standardization of care on quality and efficiency in total joint replacement surgery. J Bone Joint Surg Am (2010) 1.91
A mixed-methods analysis of patient reviews of hospital care in England: implications for public reporting of health care quality data in the United States. Jt Comm J Qual Patient Saf (2013) 1.87
Variation in diagnostic coding of patients with pneumonia and its association with hospital risk-standardized mortality rates: a cross-sectional analysis. Ann Intern Med (2014) 1.83
Early indicators of prolonged intensive care unit stay: impact of illness severity, physician staffing, and pre-intensive care unit length of stay. Crit Care Med (2003) 1.79
Activated protein C and hospital mortality in septic shock: a propensity-matched analysis. Crit Care Med (2010) 1.78
Use and outcomes associated with long-acting bronchodilators among patients hospitalized for chronic obstructive pulmonary disease. Ann Am Thorac Soc (2014) 1.71
Improving the care of patients with regard to chemotherapy-induced nausea and emesis: the effect of feedback to clinicians on adherence to antiemetic prescribing guidelines. J Clin Oncol (2003) 1.64
Putting the public back in public reporting of health care quality. JAMA (2010) 1.63
Do-not-resuscitate status and observational comparative effectiveness research in patients with septic shock*. Crit Care Med (2014) 1.62
Physician characteristics, attitudes, and use of computerized order entry. J Hosp Med (2006) 1.56
Patient knowledge and attitudes about antiviral medication and vaccination for influenza in an internal medicine clinic. Clin Infect Dis (2007) 1.55
Multicenter study comparing case definitions used to identify patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2014) 1.53
Case volume, quality of care, and care efficiency in coronary artery bypass surgery. Arch Intern Med (2010) 1.53
Patterns of obstetric infection rates in a large sample of US hospitals. Am J Obstet Gynecol (2013) 1.52
Improving nurse-to-patient staffing ratios as a cost-effective safety intervention. Med Care (2005) 1.49
A multicenter study of key stakeholders' perspectives on communicating with surrogates about prognosis in intensive care units. Ann Am Thorac Soc (2015) 1.46
Effect of a clinical pharmacist's interventions on duration of antiretroviral-related errors in hospitalized patients. Am J Health Syst Pharm (2007) 1.46
Effect of patients' awareness of CVD risk factors on health-related behaviors. South Med J (2013) 1.45
Impact of the 2008 U.S. Preventative Services Task Force recommendation on frequency of prostate-specific antigen screening in older men. J Am Geriatr Soc (2014) 1.45
Multicenter, randomized, placebo-controlled study of the nitric oxide scavenger pyridoxalated hemoglobin polyoxyethylene in distributive shock. Crit Care Med (2008) 1.45
Robot-assisted radical cystoprostatectomy in complex surgical patients: single institution report. Can J Urol (2009) 1.44
Inappropriate medication use in older adults undergoing surgery: a national study. J Am Geriatr Soc (2011) 1.43
Treatment with neuromuscular blocking agents and the risk of in-hospital mortality among mechanically ventilated patients with severe sepsis. Crit Care Med (2014) 1.42
Use of paracentesis in hospitalized patients with decompensated cirrhosis and ascites: opportunities for quality improvement. J Hosp Med (2014) 1.38
Development and validation of a model that uses enhanced administrative data to predict mortality in patients with sepsis. Crit Care Med (2011) 1.36
Trends in sepsis and infection sources in the United States. A population-based study. Ann Am Thorac Soc (2015) 1.36
Utilization patterns and outcomes associated with central venous catheter in septic shock: a population-based study. Crit Care Med (2013) 1.34
The relationship between hospital spending and mortality in patients with sepsis. Arch Intern Med (2011) 1.32
Hospitalizations for acute exacerbations of chronic obstructive pulmonary disease: how you count matters. COPD (2010) 1.29
Stakeholder priorities for comparative effectiveness research in chronic obstructive pulmonary disease: a workshop report. Am J Respir Crit Care Med (2012) 1.25
The association between body mass index and osteoporosis in patients referred for a bone mineral density examination. J Womens Health (Larchmt) (2006) 1.24
The relationship between case volume, care quality, and outcomes of complex cancer surgery. J Am Coll Surg (2010) 1.23
Validity of using ICD-9-CM codes to identify selected categories of obstetric complications, procedures and co-morbidities. Paediatr Perinat Epidemiol (2012) 1.23
Income inequality and 30 day outcomes after acute myocardial infarction, heart failure, and pneumonia: retrospective cohort study. BMJ (2013) 1.23
Hospital performance measures and 30-day readmission rates. J Gen Intern Med (2012) 1.23