Published in Int J Radiat Oncol Biol Phys on November 01, 2011
Defining radiotherapy target volumes using 18F-fluoro-deoxy-glucose positron emission tomography/computed tomography: still a Pandora's box? Int J Radiat Oncol Biol Phys (2010) 2.28
Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy. Int J Radiat Biol (2006) 3.98
Hypoxia is important in the biology and aggression of human glial brain tumors. Clin Cancer Res (2004) 2.73
Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell (2008) 2.54
Prognostic significance of tumor oxygenation in humans. Cancer Lett (2003) 1.88
18F-EF5: a new PET tracer for imaging hypoxia in head and neck cancer. J Nucl Med (2008) 1.77
Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5 binding. Cancer Res (2004) 1.59
Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome. Int J Radiat Oncol Biol Phys (2007) 1.55
Nelfinavir down-regulates hypoxia-inducible factor 1alpha and VEGF expression and increases tumor oxygenation: implications for radiotherapy. Cancer Res (2006) 1.50
Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy. PLoS One (2009) 1.37
Tumor vascular changes mediated by inhibition of oncogenic signaling. Cancer Res (2009) 1.35
Detection of reactive oxygen species via endogenous oxidative pentose phosphate cycle activity in response to oxygen concentration: implications for the mechanism of HIF-1alpha stabilization under moderate hypoxia. J Biol Chem (2007) 1.21
Catalysis of fluorine addition to double bond: an improvement of method for synthesis of (18)F PET agents. Appl Radiat Isot (2009) 1.21
p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment. Oncogene (2004) 1.18
Oxygen levels in normal and previously irradiated human skin as assessed by EF5 binding. J Invest Dermatol (2006) 1.17
Non-invasive PET and SPECT imaging of tissue hypoxia using isotopically labeled 2-nitroimidazoles. Adv Exp Med Biol (2003) 1.08
Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and gamma radiation. Mol Cancer Ther (2005) 1.05
Hypoxia and Photofrin uptake in the intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients. Clin Cancer Res (2004) 1.03
p53-Dependent and p53-independent induction of insulin-like growth factor binding protein-3 by deoxyribonucleic acid damage and hypoxia. J Clin Endocrinol Metab (2005) 1.01
EF5 binding and clinical outcome in human soft tissue sarcomas. Int J Radiat Oncol Biol Phys (2006) 1.01
VEGF regulates remodeling during permanent anatomic closure of the ductus arteriosus. Am J Physiol Regul Integr Comp Physiol (2002) 0.99
Photodynamic therapy creates fluence rate-dependent gradients in the intratumoral spatial distribution of oxygen. Cancer Res (2002) 0.98
The Relationship among Hypoxia, Proliferation, and Outcome in Patients with De Novo Glioblastoma: A Pilot Study. Transl Oncol (2010) 0.98
Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress. J Biol Chem (2002) 0.96
Early detection of radiation therapy response in non-Hodgkin's lymphoma xenografts by in vivo 1H magnetic resonance spectroscopy and imaging. NMR Biomed (2010) 0.95
Overview of radiosensitivity of human tumor cells to low-dose-rate irradiation. Int J Radiat Oncol Biol Phys (2008) 0.95
Bone marrow transplantation for feline mucopolysaccharidosis I. Mol Genet Metab (2007) 0.95
Autocrine erythropoietin signaling inhibits hypoxia-induced apoptosis in human breast carcinoma cells. Cancer Lett (2004) 0.95
Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors. Radiat Res (2008) 0.94
Vasa vasorum hypoperfusion is responsible for medial hypoxia and anatomic remodeling in the newborn lamb ductus arteriosus. Pediatr Res (2002) 0.94
The radiation response of cells from 9L gliosarcoma tumours is correlated with [F18]-EF5 uptake. Int J Radiat Biol (2009) 0.93
A quantitative overview of radiosensitivity of human tumor cells across histological type and TP53 status. Int J Radiat Biol (2008) 0.93
In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection. Cancer Res (2011) 0.93
In situ oxygen utilization in the rat intervertebral disc. J Anat (2007) 0.92
Biodistribution and dosimetry of (18)F-EF5 in cancer patients with preliminary comparison of (18)F-EF5 uptake versus EF5 binding in human glioblastoma. Eur J Nucl Med Mol Imaging (2010) 0.92
Radiation response of cells during altered protein thiol redox. Radiat Res (2003) 0.92
Mutation in G6PD gene leads to loss of cellular control of protein glutathionylation: mechanism and implication. J Cell Biochem (2008) 0.86
Radiation dosimetry and biodistribution of the hypoxia tracer (18)F-EF5 in oncologic patients. Cancer Biother Radiopharm (2012) 0.86
Non-invasive evaluation of tumour hypoxia in the Shionogi tumour model for prostate cancer with 18F-EF5 and positron emission tomography. BJU Int (2007) 0.86
Genotype-dependent radiosensitivity: clonogenic survival, apoptosis and cell-cycle redistribution. Int J Radiat Biol (2008) 0.84
Quantitative spatial analysis of hypoxia and vascular perfusion in tumor sections. Adv Exp Med Biol (2003) 0.84
Role of vicinal protein thiols in radiation and cytotoxic responses. Radiat Res (2006) 0.83
Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis. J Biomed Opt (2007) 0.83
DNA strand breakage by bivalent metal ions and ionizing radiation. Int J Radiat Biol (2007) 0.83
Tumor response to radiotherapy is dependent on genotype-associated mechanisms in vitro and in vivo. Radiat Oncol (2010) 0.83
Effects of hyperbaric oxygen exposure on experimental head and neck tumor growth, oxygenation, and vasculature. Head Neck (2005) 0.81
Radiosensitization of hypoxic tumor cells by dodecafluoropentane: a gas-phase perfluorochemical emulsion. Cancer Res (2002) 0.81
Farnesyltransferase inhibitor effects on prostate tumor micro-environment and radiation survival. Prostate (2005) 0.81
Proceedings of the Oxygen Homeostasis/Hypoxia Meeting. Cancer Res (2004) 0.80
Tumor hypoxia as a modifier of DNA strand break and cross-link repair. Curr Mol Med (2009) 0.79
Single-cell measurement of the uptake, intratumoral distribution and cell cycle effects of cisplatin using mass cytometry. Int J Cancer (2014) 0.78
In vivo colocalization of 2-nitroimidazole EF5 fluorescence intensity and electron paramagnetic resonance oximetry in mouse tumors. Radiother Oncol (2003) 0.77
Hypoxia in the androgen-dependent Shionogi model for prostate cancer at three stages. Radiat Res (2004) 0.76
pO(2)-dependent NO production determines OPPC activity in macrophages. Free Radic Biol Med (2009) 0.76
Androgen withdrawal fails to induce detectable tissue hypoxia in the rat prostate. Prostate (2014) 0.75
In regard to Vordermark et al. (Int J Radiat Oncol Biol Phys 2004;58:1242-1250). Int J Radiat Oncol Biol Phys (2004) 0.75
In regard to Brown et al. (Int J Radiat Oncol Biol Phys 2010;78:323-327). Int J Radiat Oncol Biol Phys (2011) 0.75
More on animal models for human disease and treatment. J Am Vet Med Assoc (2009) 0.75
Sequentially-induced responses define tumour cell radiosensitivity. Int J Radiat Biol (2011) 0.75