Published in Mol Pharmacol on October 07, 2011
BK potassium channel modulation by leucine-rich repeat-containing proteins. Proc Natl Acad Sci U S A (2012) 1.71
Transduction of voltage and Ca2+ signals by Slo1 BK channels. Physiology (Bethesda) (2013) 1.10
Molecular basis for differential modulation of BK channel voltage-dependent gating by auxiliary γ subunits. J Gen Physiol (2015) 1.04
MaxiK channel and cell signalling. Pflugers Arch (2014) 1.02
Regulation of BK channels by auxiliary γ subunits. Front Physiol (2014) 0.92
IFN-γ-mediated reduction of large-conductance, Ca2+-activated, voltage-dependent K+ (BK) channel activity in airway epithelial cells leads to mucociliary dysfunction. Am J Physiol Lung Cell Mol Physiol (2014) 0.91
Airway Surface Dehydration by Transforming Growth Factor β (TGF-β) in Cystic Fibrosis Is Due to Decreased Function of a Voltage-dependent Potassium Channel and Can Be Rescued by the Drug Pirfenidone. J Biol Chem (2015) 0.84
Differential efficacy of GoSlo-SR compounds on BKα and BKαγ1-4 channels. Channels (Austin) (2016) 0.83
Ca²⁺-dependent K⁺ channels in exocrine salivary glands. Cell Calcium (2014) 0.82
The single transmembrane segment determines the modulatory function of the BK channel auxiliary γ subunit. J Gen Physiol (2016) 0.80
Functional insights into modulation of BKCa channel activity to alter myometrial contractility. Front Physiol (2014) 0.79
Two distinct effects of PIP2 underlie auxiliary subunit-dependent modulation of Slo1 BK channels. J Gen Physiol (2015) 0.79
Modulation of BK Channel Function by Auxiliary Beta and Gamma Subunits. Int Rev Neurobiol (2016) 0.78
BK Channels in the Central Nervous System. Int Rev Neurobiol (2016) 0.76
Relationship between auxiliary gamma subunits and mallotoxin on BK channel modulation. Sci Rep (2017) 0.75
Airway Hydration, Apical K(+) Secretion, and the Large-Conductance, Ca(2+)-activated and Voltage-dependent Potassium (BK) Channel. Ann Am Thorac Soc (2016) 0.75
BKCa channel activation increases cardiac contractile recovery following hypothermic ischemia/reperfusion. Am J Physiol Heart Circ Physiol (2015) 0.75
The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science (1998) 39.86
Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science (2005) 17.70
Crystal structure and mechanism of a calcium-gated potassium channel. Nature (2002) 10.03
mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. Science (1993) 5.88
Coupling between voltage sensor activation, Ca2+ binding and channel opening in large conductance (BK) potassium channels. J Gen Physiol (2002) 5.18
Regulation of arterial tone by activation of calcium-dependent potassium channels. Science (1992) 4.98
Varieties of calcium-activated potassium channels. Annu Rev Physiol (1989) 4.66
High-conductance potassium channels of the SLO family. Nat Rev Neurosci (2006) 4.26
Allosteric voltage gating of potassium channels I. Mslo ionic currents in the absence of Ca(2+). J Gen Physiol (1999) 3.55
A human intermediate conductance calcium-activated potassium channel. Proc Natl Acad Sci U S A (1997) 3.12
Allosteric voltage gating of potassium channels II. Mslo channel gating charge movement in the absence of Ca(2+). J Gen Physiol (1999) 3.03
Voltage and Ca2+ activation of single large-conductance Ca2+-activated K+ channels described by a two-tiered allosteric gating mechanism. J Gen Physiol (2000) 2.41
Gating kinetics of single large-conductance Ca2+-activated K+ channels in high Ca2+ suggest a two-tiered allosteric gating mechanism. J Gen Physiol (1999) 2.35
Gating mechanism of BK (Slo1) channels: so near, yet so far. J Gen Physiol (2003) 2.31
Voltage-controlled gating in a large conductance Ca2+-sensitive K+channel (hslo). Proc Natl Acad Sci U S A (1997) 2.11
Role of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channel. J Biol Chem (1998) 2.03
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J Proteome Res (2009) 1.97
LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature (2010) 1.89
Differential effects of beta 1 and beta 2 subunits on BK channel activity. J Gen Physiol (2005) 1.88
Gating and ionic currents reveal how the BKCa channel's Ca2+ sensitivity is enhanced by its beta1 subunit. J Gen Physiol (2005) 1.79
Redox modulation of hslo Ca2+-activated K+ channels. J Neurosci (1997) 1.57
Mechanism of beta4 subunit modulation of BK channels. J Gen Physiol (2006) 1.54
Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels. Nat Med (2001) 1.43
BK channel modulators: a comprehensive overview. Curr Med Chem (2008) 1.35
Activation of the BK (SLO1) potassium channel by mallotoxin. J Biol Chem (2005) 1.17
BKCa channels activating at resting potential without calcium in LNCaP prostate cancer cells. J Membr Biol (2006) 1.10
Regulation of membrane potential and fluid secretion by Ca2+-activated K+ channels in mouse submandibular glands. J Physiol (2007) 1.09
Modulation of the Ca(2+)-dependent K+ channel, hslo, by the substituted diphenylurea NS 1608, paxilline and internal Ca2+. Neuropharmacology (1996) 1.08
High expression of a cytokeratin-associated protein in many cancers. Proc Natl Acad Sci U S A (2006) 1.08
Ca2+-independent activation of BKCa channels at negative potentials in mammalian inner hair cells. J Physiol (2005) 1.06
Molecular identification and physiological roles of parotid acinar cell maxi-K channels. J Biol Chem (2006) 1.02
Membrane-delimited inhibition of maxi-K channel activity by the intermediate conductance Ca2+-activated K channel. J Gen Physiol (2006) 1.01
Molecular identification of Ca2+-activated K+ channels in parotid acinar cells. Am J Physiol Cell Physiol (2002) 0.98
The pharmacology and molecular biology of large-conductance calcium-activated (BK) potassium channels. Adv Pharmacol (1997) 0.92
Ca2+-activated K channels in parotid acinar cells: The functional basis for the hyperpolarized activation of BK channels. Channels (Austin) (2010) 0.85
Regulation of fluid and electrolyte secretion in salivary gland acinar cells. Annu Rev Physiol (2005) 2.94
Conformation-dependent regulation of inward rectifier chloride channel gating by extracellular protons. J Physiol (2002) 1.25
Regulation of membrane potential and fluid secretion by Ca2+-activated K+ channels in mouse submandibular glands. J Physiol (2007) 1.09
External TEA block of shaker K+ channels is coupled to the movement of K+ ions within the selectivity filter. J Gen Physiol (2003) 1.07
Molecular identification and physiological roles of parotid acinar cell maxi-K channels. J Biol Chem (2006) 1.02
Membrane-delimited inhibition of maxi-K channel activity by the intermediate conductance Ca2+-activated K channel. J Gen Physiol (2006) 1.01
Functional and molecular characterization of the fluid secretion mechanism in human parotid acinar cells. Am J Physiol Regul Integr Comp Physiol (2007) 1.00
Molecular identification of Ca2+-activated K+ channels in parotid acinar cells. Am J Physiol Cell Physiol (2002) 0.98
Functional identification of ion binding sites at the internal end of the pore in Shaker K+ channels. J Physiol (2003) 0.98
Selectivity filter gating in large-conductance Ca(2+)-activated K+ channels. J Gen Physiol (2012) 0.98
Apical maxi-K (KCa1.1) channels mediate K+ secretion by the mouse submandibular exocrine gland. Am J Physiol Cell Physiol (2008) 0.95
Secretion and cell volume regulation by salivary acinar cells from mice lacking expression of the Clcn3 Cl- channel gene. J Physiol (2002) 0.94
The role of cell cholesterol and the cytoskeleton in the interaction between IK1 and maxi-K channels. Am J Physiol Cell Physiol (2009) 0.86
Ca2+-activated K channels in parotid acinar cells: The functional basis for the hyperpolarized activation of BK channels. Channels (Austin) (2010) 0.85
Two stable, conducting conformations of the selectivity filter in Shaker K+ channels. J Gen Physiol (2005) 0.85
Mechanistic details of BK channel inhibition by the intermediate conductance, Ca2+-activated K channel. Channels (Austin) (2009) 0.82
Pharmacology and surface electrostatics of the K channel outer pore vestibule. J Membr Biol (2007) 0.75