PubRank

Vipin Suri

Author PubWeight™ 10.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Targeting Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) with small molecule inhibitors for the treatment of metabolic diseases. J Biol Chem 2011 1.28
2 SIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity. PLoS One 2012 1.23
3 Molecular activation of PPARgamma by angiotensin II type 1-receptor antagonists. Vascul Pharmacol 2006 1.20
4 Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model. J Med Chem 2009 0.93
5 beta-Keto sulfones as inhibitors of 11beta-hydroxysteroid dehydrogenase type I and the mechanism of action. Bioorg Med Chem 2007 0.93
6 Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model. J Med Chem 2008 0.84
7 H6PDH interacts directly with 11beta-HSD1: implications for determining the directionality of glucocorticoid catalysis. Arch Biochem Biophys 2008 0.83
8 Synthesis and biological evaluation of sulfonamidooxazoles and beta-keto sulfones: selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I. Bioorg Med Chem Lett 2005 0.82
9 PHARMACOLOGICAL SIRT1 ACTIVATION IMPROVES MORTALITY AND MARKEDLY ALTERS TRANSCRIPTIONAL PROFILES THAT ACCOMPANY EXPERIMENTAL SEPSIS. Shock 2016 0.78
10 Sirt1 Activation Markedly Alters Transcription Profiles and Improves Outcome in Experimental Sepsis. Shock 2015 0.77
11 Comparative pharmacokinetics and metabolism studies in lean and diet- induced obese mice: an animal efficacy model for 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors. Drug Metab Lett 2011 0.76
12 Serine Is an Essential Metabolite for Effector T Cell Expansion. Cell Metab 2017 0.75