Published in J Neurosci on October 12, 2011
Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair. Nat Rev Neurosci (2012) 2.27
Axonally synthesized ATF4 transmits a neurodegenerative signal across brain regions. Cell (2014) 1.89
Axonal transcription factors signal retrogradely in lesioned peripheral nerve. EMBO J (2012) 1.77
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Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity. EMBO J (2011) 1.49
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Cooperative roles of BDNF expression in neurons and Schwann cells are modulated by exercise to facilitate nerve regeneration. J Neurosci (2012) 1.19
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Dynamic Change and Target Prediction of Axon-Specific MicroRNAs in Regenerating Sciatic Nerve. PLoS One (2015) 0.76
Adenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain. Curr Drug Targets (2016) 0.76
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When zip codes are in short supply. EMBO J (2011) 0.75
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An essential role for beta-actin mRNA localization and translation in Ca2+-dependent growth cone guidance. Nat Neurosci (2006) 3.30
Axonal protein synthesis provides a mechanism for localized regulation at an intermediate target. Cell (2002) 3.11
Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron (2005) 3.09
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Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs. J Cell Biol (2007) 2.54
Axonal mRNA in uninjured and regenerating cortical mammalian axons. J Neurosci (2009) 2.48
A functional role for intra-axonal protein synthesis during axonal regeneration from adult sensory neurons. J Neurosci (2001) 2.48
Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration. J Neurosci (2005) 2.42
Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival. Nat Cell Biol (2008) 2.37
Activity-dependent trafficking and dynamic localization of zipcode binding protein 1 and beta-actin mRNA in dendrites and spines of hippocampal neurons. J Neurosci (2003) 2.34
A transgenic mouse for in vivo detection of endogenous labeled mRNA. Nat Methods (2011) 2.27
Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve. Neuron (2008) 2.04
MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons. J Neurosci (2008) 1.78
Local translation in primary afferent fibers regulates nociception. PLoS One (2008) 1.70
An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons. Nat Neurosci (2010) 1.68
Schwann cell to axon transfer of ribosomes: toward a novel understanding of the role of glia in the nervous system. J Neurosci (2008) 1.60
IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex. J Neurosci (2010) 1.52
Axonal transport of neuropeptide encoding mRNAs within the hypothalamo-hypophyseal tract of rats. EMBO J (1991) 1.38
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Cryptic peripheral ribosomal domains distributed intermittently along mammalian myelinated axons. J Neurosci (2000) 1.35
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Neurotrophin-4/5 is required for the early growth of regenerating axons in peripheral nerves. Eur J Neurosci (2005) 1.20
Locally synthesized calcitonin gene-related Peptide has a critical role in peripheral nerve regeneration. J Neuropathol Exp Neurol (2009) 1.11
Conserved 3'-untranslated region sequences direct subcellular localization of chaperone protein mRNAs in neurons. J Biol Chem (2010) 1.10
Myelinated axons contain beta-actin mRNA and ZBP-1 in periaxoplasmic ribosomal plaques and depend on cyclic AMP and F-actin integrity for in vitro translation. J Neurochem (2007) 1.08
Recovery of electromyographic activity after transection and surgical repair of the rat sciatic nerve. J Neurophysiol (2006) 1.03
Olfactory marker protein mRNA is found in axons of olfactory receptor neurons. J Neurosci (1995) 0.96
Evidence for developmentally regulated local translation of odorant receptor mRNAs in the axons of olfactory sensory neurons. J Neurosci (2009) 0.96
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Diversity of mRNAs in the Axonal Compartment of Peptidergic Neurons in the Rat. Eur J Neurosci (1992) 0.89
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Localization of calcitonin gene-related peptide mRNA in developing olfactory axons. Cell Tissue Res (1998) 0.87
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature (2005) 5.29
SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN. Hum Mol Genet (2005) 5.23
Rett syndrome: revised diagnostic criteria and nomenclature. Ann Neurol (2010) 4.03
The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system. J Neurosci (2008) 3.54
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An essential role for beta-actin mRNA localization and translation in Ca2+-dependent growth cone guidance. Nat Neurosci (2006) 3.30
Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons. J Neurosci (2005) 2.98
Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses. J Neurosci (2004) 2.59
Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways. Hum Mol Genet (2007) 2.55
Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs. J Cell Biol (2007) 2.54
ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury. Neuron (2002) 2.53
Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria. J Neurosci (2007) 2.51
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev Cell (2008) 2.51
Plastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy. Science (2008) 2.51
Activity-dependent trafficking and dynamic localization of zipcode binding protein 1 and beta-actin mRNA in dendrites and spines of hippocampal neurons. J Neurosci (2003) 2.34
Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization. J Neurosci (2003) 2.28
Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling. Mol Cell (2011) 2.27
HDAC6 is a target for protection and regeneration following injury in the nervous system. Proc Natl Acad Sci U S A (2009) 2.14
Survival motor neuron function in motor axons is independent of functions required for small nuclear ribonucleoprotein biogenesis. J Neurosci (2006) 2.11
Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors. Proc Natl Acad Sci U S A (2007) 2.10
Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis. Nature (2012) 2.08
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization. RNA (2010) 2.07
Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve. Neuron (2008) 2.04
FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A. J Neurosci (2007) 2.02
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The comorbidity of autism with the genomic disorders of chromosome 15q11.2-q13. Neurobiol Dis (2008) 1.97
High-resolution molecular characterization of 15q11-q13 rearrangements by array comparative genomic hybridization (array CGH) with detection of gene dosage. Am J Hum Genet (2004) 1.94
An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke. Nat Neurosci (2010) 1.89
Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome. J Neurosci (2010) 1.89
Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses. Mol Cell Neurosci (2006) 1.88
A previously unidentified MECP2 open reading frame defines a new protein isoform relevant to Rett syndrome. Nat Genet (2004) 1.88
S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascade. J Biol Chem (2008) 1.87
Axon regeneration in peripheral nerves is enhanced by proteoglycan degradation. Exp Neurol (2005) 1.84
Local RNA translation at the synapse and in disease. J Neurosci (2011) 1.83
JNK3 perpetuates metabolic stress induced by Aβ peptides. Neuron (2012) 1.80
Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons. J Neurosci (2006) 1.80
A digital atlas to characterize the mouse brain transcriptome. PLoS Comput Biol (2005) 1.78
A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons. J Cell Biol (2002) 1.77
Axonal transcription factors signal retrogradely in lesioned peripheral nerve. EMBO J (2012) 1.77
Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses. J Neurosci (2003) 1.74
HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nat Neurosci (2011) 1.67
Axonal degeneration is mediated by the mitochondrial permeability transition pore. J Neurosci (2011) 1.67
Activity bidirectionally regulates AMPA receptor mRNA abundance in dendrites of hippocampal neurons. J Neurosci (2006) 1.60
Phosphorylation of a carboxyl-terminal serine within the kappa-opioid receptor produces desensitization and internalization. J Biol Chem (2003) 1.58
RNA transport and localized protein synthesis in neurological disorders and neural repair. Dev Neurobiol (2007) 1.52
Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis. J Neurosci (2002) 1.49
Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity. EMBO J (2011) 1.49
Sumoylation in axons triggers retrograde transport of the RNA-binding protein La. Proc Natl Acad Sci U S A (2007) 1.45
DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2. Mol Cell Biol (2005) 1.41
A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci (2008) 1.40
Single molecule-sensitive probes for imaging RNA in live cells. Nat Methods (2009) 1.40
The interstitial duplication 15q11.2-q13 syndrome includes autism, mild facial anomalies and a characteristic EEG signature. Autism Res (2013) 1.36
The evolving roles of axonally synthesized proteins in regeneration. Curr Opin Neurobiol (2006) 1.34
Netrin-1-induced local β-actin synthesis and growth cone guidance requires zipcode binding protein 1. J Neurosci (2011) 1.32
Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits. Proc Natl Acad Sci U S A (2011) 1.32
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Axonally synthesized β-actin and GAP-43 proteins support distinct modes of axonal growth. J Neurosci (2013) 1.30
Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2. J Neurosci (2011) 1.30
Phosphorylation of zipcode binding protein 1 is required for brain-derived neurotrophic factor signaling of local beta-actin synthesis and growth cone turning. J Neurosci (2010) 1.29
Neurotrophin p75 receptor (p75NTR) promotes endothelial cell apoptosis and inhibits angiogenesis: implications for diabetes-induced impaired neovascularization in ischemic limb muscles. Circ Res (2008) 1.29
Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex. Mol Cell (2012) 1.29
Voluntary exercise increases axonal regeneration from sensory neurons. Proc Natl Acad Sci U S A (2004) 1.28
Subcellular knockout of importin β1 perturbs axonal retrograde signaling. Neuron (2012) 1.28
Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells. J Biol Chem (2002) 1.28
Spinal muscular atrophy: the role of SMN in axonal mRNA regulation. Brain Res (2012) 1.26
Treadmill training promotes axon regeneration in injured peripheral nerves. Exp Neurol (2008) 1.26
Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo. J Cell Sci (2008) 1.26
The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons. J Neurosci (2011) 1.25
The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth. Hum Mol Genet (2012) 1.25
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Subcellular communication through RNA transport and localized protein synthesis. Traffic (2010) 1.22
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GAP-43 mRNA in growth cones is associated with HuD and ribosomes. J Neurobiol (2004) 1.21
Dynamics of axonal mRNA transport and implications for peripheral nerve regeneration. Exp Neurol (2009) 1.21
Cooperative roles of BDNF expression in neurons and Schwann cells are modulated by exercise to facilitate nerve regeneration. J Neurosci (2012) 1.19
Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death. J Neurosci (2006) 1.19
The role of ErbB2 signaling in the onset of terminal differentiation of oligodendrocytes in vivo. J Neurosci (2003) 1.17
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Making and breaking synapses through local mRNA regulation. Curr Opin Genet Dev (2011) 1.17
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