PubRank

Hartmut Beug

Author PubWeight™ 126.56‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol 2005 11.46
2 DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene 2005 5.74
3 Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. J Cell Biol 2002 5.07
4 NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest 2004 5.06
5 Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat Rev Mol Cell Biol 2003 4.53
6 p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway. Nat Genet 2007 3.19
7 Autocrine PDGFR signaling promotes mammary cancer metastasis. J Clin Invest 2006 2.68
8 Expression profiling of epithelial plasticity in tumor progression. Oncogene 2003 2.67
9 Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis. Mutat Res 2004 2.45
10 Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation. Blood 2006 2.38
11 Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-beta1 and Ha-Ras: steps towards invasiveness. J Cell Sci 2002 2.32
12 ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells. Cancer Cell 2006 2.30
13 Stat5 tetramer formation is associated with leukemogenesis. Cancer Cell 2005 2.26
14 Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia. EMBO Mol Med 2010 2.23
15 Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth. Neoplasia 2005 2.18
16 Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis. Cell 2011 2.11
17 The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability. Mol Cell Biol 2005 2.11
18 Evidence for a size-sensing mechanism in animal cells. Nat Cell Biol 2004 2.09
19 STAT1 acts as a tumor promoter for leukemia development. Cancer Cell 2006 2.00
20 Membrane lipidome of an epithelial cell line. Proc Natl Acad Sci U S A 2011 1.87
21 beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition. Oncogene 2004 1.79
22 Tumor cell invasiveness correlates with changes in integrin expression and localization. Oncogene 2005 1.73
23 Different steroids co-regulate long-term expansion versus terminal differentiation in primary human erythroid progenitors. Blood 2004 1.70
24 NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells. Cancer Lett 2010 1.67
25 HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells. Proc Natl Acad Sci U S A 2005 1.65
26 Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells. Blood 2004 1.62
27 FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. J Cell Biol 2004 1.51
28 Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias. Blood 2006 1.50
29 Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression. Genes Dev 2007 1.45
30 Epithelial-mesenchymal transition: NF-kappaB takes center stage. Cell Cycle 2004 1.38
31 Apoptosis protection by the Epo target Bcl-X(L) allows factor-independent differentiation of primary erythroblasts. Curr Biol 2002 1.37
32 The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression. FEBS Lett 2007 1.36
33 Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1. Blood 2008 1.31
34 Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth. Genes Dev 2004 1.30
35 Differential regulation of Foxo3a target genes in erythropoiesis. Mol Cell Biol 2007 1.26
36 Mechanisms in epithelial plasticity and metastasis: insights from 3D cultures and expression profiling. J Mammary Gland Biol Neoplasia 2002 1.26
37 Cooperative signaling between cytokine receptors and the glucocorticoid receptor in the expansion of erythroid progenitors: molecular analysis by expression profiling. Blood 2003 1.23
38 Raf-1 antagonizes erythroid differentiation by restraining caspase activation. J Exp Med 2002 1.23
39 Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis. Blood 2006 1.21
40 Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2. Blood 2008 1.20
41 Nuclear beta-catenin induces an early liver progenitor phenotype in hepatocellular carcinoma and promotes tumor recurrence. Am J Pathol 2009 1.18
42 Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1. EMBO J 2006 1.16
43 Annexin A1 attenuates EMT and metastatic potential in breast cancer. EMBO Mol Med 2010 1.14
44 Oncogenic Ras/Her-2 mediate hyperproliferation of polarized epithelial cells in 3D cultures and rapid tumor growth via the PI3K pathway. Oncogene 2002 1.08
45 The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis. Oncogene 2003 1.08
46 Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers. Oncogene 2002 1.08
47 The different functions of Stat5 and chromatin alteration through Stat5 proteins. Front Biosci 2008 1.05
48 Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation. Blood 2010 1.04
49 Integration of Ras subeffector signaling in TGF-beta mediated late stage hepatocarcinogenesis. Carcinogenesis 2005 1.04
50 La enhances IRES-mediated translation of laminin B1 during malignant epithelial to mesenchymal transition. Nucleic Acids Res 2011 1.03
51 Expansion and differentiation of immature mouse and human hematopoietic progenitors. Methods Mol Med 2005 1.02
52 Immortalized p19ARF null hepatocytes restore liver injury and generate hepatic progenitors after transplantation. Hepatology 2004 1.00
53 Control of erythropoiesis by erythropoietin and stem cell factor: a novel role for Bruton's tyrosine kinase. Cell Cycle 2004 0.98
54 Cell size control: new evidence for a general mechanism. Cell Cycle 2005 0.96
55 The dark and the bright side of Stat3: proto-oncogene and tumor-suppressor. Front Biosci (Landmark Ed) 2009 0.96
56 Epithelial-mesenchymal transition in pancreatic carcinoma. Cancers (Basel) 2010 0.94
57 Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors. J Exp Med 2004 0.93
58 MLL-ENL cooperates with SCF to transform primary avian multipotent cells. EMBO J 2002 0.91
59 The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity. Biol Chem 2004 0.90
60 Igbp1 is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation. Blood 2008 0.90
61 Enhanced tenascin-C expression and matrix deposition during Ras/TGF-beta-induced progression of mammary tumor cells. Oncogene 2004 0.90
62 A balance between Raf-1 and Fas expression sets the pace of erythroid differentiation. Blood 2006 0.89
63 Translational control of putative protooncogene Nm23-M2 by cytokines via phosphoinositide 3-kinase signaling. J Biol Chem 2004 0.89
64 LAP2alpha-binding protein LINT-25 is a novel chromatin-associated protein involved in cell cycle exit. J Cell Sci 2007 0.88
65 Diverging fates of cells of origin in acute and chronic leukaemia. EMBO Mol Med 2012 0.86
66 Inhibition of proliferation and expression of T1 and cyclin D1 genes by thyroid hormone in mammary epithelial cells. Mol Carcinog 2002 0.86
67 Semaphorin-7a reverses the ERF-induced inhibition of EMT in Ras-dependent mouse mammary epithelial cells. Mol Biol Cell 2012 0.86
68 Up-regulation of SLAP in FLI-1-transformed erythroblasts interferes with EpoR signaling. Blood 2003 0.84
69 Thyroid hormone T3 acting through the thyroid hormone alpha receptor is necessary for implementation of erythropoiesis in the neonatal spleen environment in the mouse. Development 2005 0.84
70 Cellular repressor of E1A-stimulated genes is a bona fide lysosomal protein which undergoes proteolytic maturation during its biosynthesis. Exp Cell Res 2008 0.84
71 p38α controls erythroblast enucleation and Rb signaling in stress erythropoiesis. Cell Res 2011 0.83
72 FIP-2, an IkappaB-kinase-gamma-related protein, is associated with the Golgi apparatus and translocates to the marginal band during chicken erythroblast differentiation. Exp Cell Res 2002 0.83
73 The MEK-1/ERKs signalling pathway is differentially involved in the self-renewal of early and late avian erythroid progenitor cells. Oncogene 2003 0.83
74 BI 5700, a Selective Chemical Inhibitor of IκB Kinase 2, Specifically Suppresses Epithelial-Mesenchymal Transition and Metastasis in Mouse Models of Tumor Progression. Genes Cancer 2010 0.80
75 Interleukin-like epithelial-to-mesenchymal transition inducer activity is controlled by proteolytic processing and plasminogen-urokinase plasminogen activator receptor system-regulated secretion during breast cancer progression. Breast Cancer Res 2014 0.77
76 A novel conserved phosphotyrosine motif in the Drosophila fibroblast growth factor signaling adaptor Dof with a redundant role in signal transmission. Mol Cell Biol 2010 0.77
77 Transferrin receptor hyperexpression in primary erythroblasts is lost on transformation by avian erythroblastosis virus. Blood 2002 0.75
78 c-Myc is required for transformation of FDC-P1 cells by EGFRvIII. FEBS Lett 2007 0.75