Published in Blood on September 09, 2004
Biologic properties and enucleation of red blood cells from human embryonic stem cells. Blood (2008) 3.01
Proof of principle for transfusion of in vitro-generated red blood cells. Blood (2011) 3.01
Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin. Nat Genet (2010) 2.50
Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus. Blood (2010) 1.91
Low testosterone levels and the risk of anemia in older men and women. Arch Intern Med (2006) 1.61
The majority of the in vitro erythroid expansion potential resides in CD34(-) cells, outweighing the contribution of CD34(+) cells and significantly increasing the erythroblast yield from peripheral blood samples. Haematologica (2010) 1.39
Investigating the key membrane protein changes during in vitro erythropoiesis of protein 4.2 (-) cells (mutations Chartres 1 and 2). Haematologica (2010) 1.12
Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes. Proc Natl Acad Sci U S A (2014) 1.09
Humanized culture medium for clinical expansion of human erythroblasts. Cell Transplant (2010) 1.07
EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence. Epigenetics Chromatin (2009) 1.05
Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients. PLoS One (2012) 0.99
Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation. Autophagy (2013) 0.98
Fetal globin expression is regulated by Friend of Prmt1. Blood (2010) 0.94
The dominant negative β isoform of the glucocorticoid receptor is uniquely expressed in erythroid cells expanded from polycythemia vera patients. Blood (2011) 0.92
Hydroxyurea responsiveness in β-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity. Haematologica (2012) 0.91
Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors. Mol Ther (2013) 0.90
Minireview: Nuclear receptors, hematopoiesis, and stem cells. Mol Endocrinol (2009) 0.87
A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress. Autophagy (2012) 0.87
Novel, high-yield red blood cell production methods from CD34-positive cells derived from human embryonic stem, yolk sac, fetal liver, cord blood, and peripheral blood. Stem Cells Transl Med (2012) 0.87
Dexamethasone targeted directly to macrophages induces macrophage niches that promote erythroid expansion. Haematologica (2014) 0.85
Rapid and Efficient Generation of Transgene-Free iPSC from a Small Volume of Cryopreserved Blood. Stem Cell Rev (2015) 0.83
Concise review: production of cultured red blood cells from stem cells. Stem Cells Transl Med (2012) 0.82
Ex-vivo expansion of red blood cells: how real for transfusion in humans? Blood Rev (2011) 0.81
Erythroid differentiation of human induced pluripotent stem cells is independent of donor cell type of origin. Haematologica (2014) 0.80
Concise review: stem cell-based approaches to red blood cell production for transfusion. Stem Cells Transl Med (2013) 0.79
Progress towards mechanism-based treatment for Diamond-Blackfan anemia. ScientificWorldJournal (2012) 0.78
Manufacturing blood ex vivo: a futuristic approach to deal with the supply and safety concerns. Front Cell Dev Biol (2014) 0.78
In vitro large scale production of human mature red blood cells from hematopoietic stem cells by coculturing with human fetal liver stromal cells. Biomed Res Int (2013) 0.77
Thryroid hormones and hematological indices levels in thyroid disorders patients at moi teaching and referral hospital, Western kenya. ISRN Endocrinol (2013) 0.76
TAF10 Interacts with the GATA1 Transcription Factor and Controls Mouse Erythropoiesis. Mol Cell Biol (2015) 0.75
Polyurethane scaffolds seeded with CD34(+) cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors. Sci Rep (2016) 0.75
The Role of the Multiple Hormonal Dysregulation in the Onset of "Anemia of Aging": Focus on Testosterone, IGF-1, and Thyroid Hormones. Int J Endocrinol (2015) 0.75
The role of glucocorticoid receptor (GR) polymorphisms in human erythropoiesis. Am J Blood Res (2014) 0.75
Genetically Engineered In Vitro Erythropoiesis. Int J Stem Cells (2016) 0.75
Androgens correlate with increased erythropoiesis in women with congenital adrenal hyperplasia. Clin Endocrinol (Oxf) (2016) 0.75
Role of stem cell factor in the reactivation of human fetal hemoglobin. Mediterr J Hematol Infect Dis (2009) 0.75
Iron dose-dependent differentiation and enucleation of human erythroblasts in serum-free medium. J Tissue Eng Regen Med (2013) 0.75
Effect of age, sex and physiological stages on hematological indices of Banni buffalo (Bubalus bubalis). Vet World (2016) 0.75
Evaluation of Stem Cell-Derived Red Blood Cells as a Transfusion Product Using a Novel Animal Model. PLoS One (2016) 0.75
Mononuclear cells from a rare blood donor, after freezing under good manufacturing practice conditions, generate red blood cells that recapitulate the rare blood phenotype. Transfusion (2013) 0.75
Development of autologous blood cell therapies. Exp Hematol (2016) 0.75
Anemia in Patients With Resistance to Thyroid Hormone α: A Role for Thyroid Hormone Receptor α in Human Erythropoiesis. J Clin Endocrinol Metab (2017) 0.75
Weekly low-dose docetaxel combined with estramustine and dexamethasone for Japanese patients with metastatic castration-resistant prostate cancer. Int J Clin Oncol (2012) 0.75
SIRT1 Activates the Expression of Fetal Hemoglobin Genes. Am J Hematol (2017) 0.75
Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol (2005) 11.46
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene (2005) 5.74
Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. J Cell Biol (2002) 5.07
NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest (2004) 5.06
Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat Rev Mol Cell Biol (2003) 4.53
p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway. Nat Genet (2007) 3.19
Autocrine PDGFR signaling promotes mammary cancer metastasis. J Clin Invest (2006) 2.68
Expression profiling of epithelial plasticity in tumor progression. Oncogene (2003) 2.67
Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis. Mutat Res (2004) 2.45
Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation. Blood (2006) 2.38
Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-beta1 and Ha-Ras: steps towards invasiveness. J Cell Sci (2002) 2.32
ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells. Cancer Cell (2006) 2.30
Stat5 tetramer formation is associated with leukemogenesis. Cancer Cell (2005) 2.26
Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia. EMBO Mol Med (2010) 2.23
Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth. Neoplasia (2005) 2.18
A combination treatment of prednisone, aspirin, folate, and progesterone in women with idiopathic recurrent miscarriage: a matched-pair study. Fertil Steril (2006) 2.18
Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis. Cell (2011) 2.11
The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability. Mol Cell Biol (2005) 2.11
Evidence for a size-sensing mechanism in animal cells. Nat Cell Biol (2004) 2.09
STAT1 acts as a tumor promoter for leukemia development. Cancer Cell (2006) 2.00
Membrane lipidome of an epithelial cell line. Proc Natl Acad Sci U S A (2011) 1.87
beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition. Oncogene (2004) 1.79
Tumor cell invasiveness correlates with changes in integrin expression and localization. Oncogene (2005) 1.73
NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells. Cancer Lett (2010) 1.67
HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells. Proc Natl Acad Sci U S A (2005) 1.65
Hyperprolactinaemia and antipsychotic therapy in schizophrenia. Curr Med Res Opin (2004) 1.64
Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells. Blood (2004) 1.62
FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. J Cell Biol (2004) 1.51
Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias. Blood (2006) 1.50
Isolation of polysome-bound mRNA from solid tissues amenable for RT-PCR and profiling experiments. RNA (2007) 1.49
Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression. Genes Dev (2007) 1.45
Epithelial-mesenchymal transition: NF-kappaB takes center stage. Cell Cycle (2004) 1.38
Apoptosis protection by the Epo target Bcl-X(L) allows factor-independent differentiation of primary erythroblasts. Curr Biol (2002) 1.37
The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression. FEBS Lett (2007) 1.36
Classification and pharmacology of progestins. Maturitas (2003) 1.36
A novel stereotactic prostate biopsy system integrating pre-interventional magnetic resonance imaging and live ultrasound fusion. J Urol (2011) 1.34
Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1. Blood (2008) 1.31
Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth. Genes Dev (2004) 1.30
Differential regulation of Foxo3a target genes in erythropoiesis. Mol Cell Biol (2007) 1.26
Mechanisms in epithelial plasticity and metastasis: insights from 3D cultures and expression profiling. J Mammary Gland Biol Neoplasia (2002) 1.26
Raf-1 antagonizes erythroid differentiation by restraining caspase activation. J Exp Med (2002) 1.23
Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis. Blood (2006) 1.21
Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2. Blood (2008) 1.20
Nuclear beta-catenin induces an early liver progenitor phenotype in hepatocellular carcinoma and promotes tumor recurrence. Am J Pathol (2009) 1.18
Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1. EMBO J (2006) 1.16
Fluorescent conjugated polymer nanoparticles by polymerization in miniemulsion. J Am Chem Soc (2009) 1.16
Annexin A1 attenuates EMT and metastatic potential in breast cancer. EMBO Mol Med (2010) 1.14
The impact of age, body mass index and testosterone on erectile dysfunction. J Urol (2005) 1.11
What really matters is rarely measured: outcome of routine care and patient-reported outcomes. Eur Urol (2013) 1.09
Oncogenic Ras/Her-2 mediate hyperproliferation of polarized epithelial cells in 3D cultures and rapid tumor growth via the PI3K pathway. Oncogene (2002) 1.08
The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis. Oncogene (2003) 1.08
Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers. Oncogene (2002) 1.08
Infertility caused by PCOS--health-related quality of life among Austrian and Moslem immigrant women in Austria. Hum Reprod (2004) 1.07
Classification and pharmacology of progestins. Maturitas (2009) 1.06
The different functions of Stat5 and chromatin alteration through Stat5 proteins. Front Biosci (2008) 1.05
Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation. Blood (2010) 1.04
Integration of Ras subeffector signaling in TGF-beta mediated late stage hepatocarcinogenesis. Carcinogenesis (2005) 1.04
La enhances IRES-mediated translation of laminin B1 during malignant epithelial to mesenchymal transition. Nucleic Acids Res (2011) 1.03
Expansion and differentiation of immature mouse and human hematopoietic progenitors. Methods Mol Med (2005) 1.02
Characterization of colon cancer cells: a functional approach characterizing CD133 as a potential stem cell marker. BMC Cancer (2012) 1.01
Orthotopic microvascular reanastomosis of whole cryopreserved ovine ovaries resulting in pregnancy and live birth. Fertil Steril (2006) 1.01
Immortalized p19ARF null hepatocytes restore liver injury and generate hepatic progenitors after transplantation. Hepatology (2004) 1.00
Treatment decision-making in localized prostate cancer: why patients chose either radical prostatectomy or external beam radiation therapy. BJU Int (2011) 0.99
Control of erythropoiesis by erythropoietin and stem cell factor: a novel role for Bruton's tyrosine kinase. Cell Cycle (2004) 0.98
Cell size control: new evidence for a general mechanism. Cell Cycle (2005) 0.96
The dark and the bright side of Stat3: proto-oncogene and tumor-suppressor. Front Biosci (Landmark Ed) (2009) 0.96
Elevated coagulation factor VIII and the risk for recurrent early pregnancy loss. Thromb Haemost (2004) 0.95
Epithelial-mesenchymal transition in pancreatic carcinoma. Cancers (Basel) (2010) 0.94
Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors. J Exp Med (2004) 0.93
Plasminogen activator inhibitor 1 4G/5G polymorphism and coagulation factor XIII Val34Leu polymorphism: impaired fibrinolysis and early pregnancy loss. Clin Chem (2003) 0.93
MLL-ENL cooperates with SCF to transform primary avian multipotent cells. EMBO J (2002) 0.91
Comparative analysis of late functional outcome following preoperative radiation therapy or chemoradiotherapy and surgery or surgery alone in rectal cancer. Int J Colorectal Dis (2013) 0.91
Tailor-made conjugated polymer nanoparticles for multicolor and multiphoton cell imaging. Biomacromolecules (2010) 0.90
Enhanced tenascin-C expression and matrix deposition during Ras/TGF-beta-induced progression of mammary tumor cells. Oncogene (2004) 0.90
The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity. Biol Chem (2004) 0.90
Igbp1 is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation. Blood (2008) 0.90
Combined thrombophilic polymorphisms in women with idiopathic recurrent miscarriage. Fertil Steril (2003) 0.90
A balance between Raf-1 and Fas expression sets the pace of erythroid differentiation. Blood (2006) 0.89
Translational control of putative protooncogene Nm23-M2 by cytokines via phosphoinositide 3-kinase signaling. J Biol Chem (2004) 0.89
When do we need to care about the caregiver? Supportive care needs, anxiety, and depression among informal caregivers of patients with cancer and cancer survivors. Cancer (2015) 0.89
Prognostic variables for shockwave lithotripsy (SWL) treatment success: no impact of body mass index (BMI) using a third generation lithotripter. BJU Int (2011) 0.89
Prognostic value of melanoma-associated antigen A9 in renal cell carcinoma. Scand J Urol (2012) 0.89
LAP2alpha-binding protein LINT-25 is a novel chromatin-associated protein involved in cell cycle exit. J Cell Sci (2007) 0.88
Lack of association of TNFalpha gene polymorphisms and recurrent pregnancy loss in Caucasian women. J Reprod Immunol (2004) 0.88
Creation of a neovagina according to Wharton-Sheares-George in patients with Mayer-Rokitansky-Küster-Hauser syndrome. Fertil Steril (2005) 0.88
Gender and age differences in lean soft tissue mass and sarcopenia among healthy elderly. Anthropol Anz (2009) 0.87
Diverging fates of cells of origin in acute and chronic leukaemia. EMBO Mol Med (2012) 0.86
Inhibition of proliferation and expression of T1 and cyclin D1 genes by thyroid hormone in mammary epithelial cells. Mol Carcinog (2002) 0.86
Semaphorin-7a reverses the ERF-induced inhibition of EMT in Ras-dependent mouse mammary epithelial cells. Mol Biol Cell (2012) 0.86