Published in Cutis on September 01, 2011
PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization. Biochem J (2003) 3.43
Interstitial granulomatous drug reaction to anakinra. J Am Acad Dermatol (2008) 1.85
A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway. Cell (2013) 1.75
Sterile inflammation associated with transradial catheterization and hydrophilic sheaths. Catheter Cardiovasc Interv (2003) 1.52
Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5. Biochem J (2006) 1.46
Phosphorylation of RACK1 on tyrosine 52 by c-Abl is required for insulin-like growth factor I-mediated regulation of focal adhesion kinase. J Biol Chem (2009) 1.33
DNA variations in oculocutaneous albinism: an updated mutation list and current outstanding issues in molecular diagnostics. Hum Mutat (2013) 1.25
Eczema herpeticum: a dermatologic emergency. Dermatol Nurs (2002) 1.25
An analysis of exome sequencing for diagnostic testing of the genes associated with muscle disease and spastic paraplegia. Hum Mutat (2012) 1.25
Analysis of group differences in processing speed: Brinley plots, Q-Q plots, and other conspiracies. Psychon Bull Rev (2003) 1.18
The National Institutes of Health undiagnosed diseases program. Curr Opin Pediatr (2014) 1.14
Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays. Biochem J (2007) 1.10
Synthesis and biological activity of some structural modifications of pancratistatin. Bioorg Med Chem Lett (2004) 1.09
Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality. Cancer Cell (2013) 1.08
Novel anti-infective compounds from marine bacteria. Mar Drugs (2010) 1.08
MEK1 binds directly to betaarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization. J Biol Chem (2009) 1.02
Nitisinone improves eye and skin pigmentation defects in a mouse model of oculocutaneous albinism. J Clin Invest (2011) 0.99
Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. Mol Pharmacol (2011) 0.99
Transdifferentiation-inducing HCCR-1 oncogene. BMC Cell Biol (2010) 0.97
Atypical patterns of inheritance. Semin Pediatr Neurol (2007) 0.95
Biofilm-specific cross-species induction of antimicrobial compounds in bacilli. Appl Environ Microbiol (2003) 0.94
The development of a marine natural product-based antifouling paint. Biofouling (2003) 0.93
High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules. Biochem J (2010) 0.93
Antagonists of the human adenosine A2A receptor. Part 1: Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives. Bioorg Med Chem Lett (2008) 0.92
Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK. Biochem J (2010) 0.91
RACK1 to the future--a historical perspective. Cell Commun Signal (2013) 0.90
Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4). J Med Chem (2011) 0.90
Bleomycin induces the extrinsic apoptotic pathway in pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol (2010) 0.90
Spa contact dermatitis. Dermatitis (2008) 0.89
Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process. Cell Signal (2003) 0.88
A scanning peptide array approach uncovers association sites within the JNK/beta arrestin signalling complex. FEBS Lett (2009) 0.88
Retinoic acid inhibits airway smooth muscle cell migration. Am J Respir Cell Mol Biol (2006) 0.88
Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs. FASEB J (2012) 0.88
Direct interaction between scaffolding proteins RACK1 and 14-3-3ζ regulates brain-derived neurotrophic factor (BDNF) transcription. J Biol Chem (2011) 0.88
Free sialic acid storage disease without sialuria. Ann Neurol (2009) 0.87
Recombination mapping using Boolean logic and high-density SNP genotyping for exome sequence filtering. Mol Genet Metab (2011) 0.86
Comparative effects of single-mode vs. duration-matched concurrent exercise training on body composition, low-grade inflammation, and glucose regulation in sedentary, overweight, middle-aged men. Appl Physiol Nutr Metab (2013) 0.85
Angiotensin II activates AMPK for execution of apoptosis through energy-dependent and -independent mechanisms. Am J Physiol Lung Cell Mol Physiol (2011) 0.85
Allopurinol hypersensitivity syndrome. J Drugs Dermatol (2002) 0.83
Effect of ONCONASE +/- tamoxifen on ASPC-1 human pancreatic tumors in nude mice. Adv Exp Med Biol (2003) 0.83
p62 (SQSTM1) and cyclic AMP phosphodiesterase-4A4 (PDE4A4) locate to a novel, reversible protein aggregate with links to autophagy and proteasome degradation pathways. Cell Signal (2010) 0.83
Putting the lid on phosphodiesterase 4. Nat Biotechnol (2010) 0.83
Chemoenzymatic synthesis of inositols, conduritols, and cyclitol analogues. Chem Rev (2011) 0.83
Expression, intracellular distribution and basis for lack of catalytic activity of the PDE4A7 isoform encoded by the human PDE4A cAMP-specific phosphodiesterase gene. Biochem J (2004) 0.82
JM47, a cyclic tetrapeptide HC-toxin analogue from a marine Fusarium species. Phytochemistry (2002) 0.81
Diagnosis of Paget's disease of the pelvis using F-18 FDG PET/CT. Int J Rheum Dis (2010) 0.81
Phosphodiesterase inhibitors. Part 3: Design, synthesis and structure-activity relationships of dual PDE3/4-inhibitory fused bicyclic heteroaromatic-dihydropyridazinones with anti-inflammatory and bronchodilatory activity. Bioorg Med Chem (2012) 0.80
Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1). Eur J Biochem (2003) 0.80
Synergistic signaling of tumor cell invasiveness by hepatocyte growth factor and hypoxia. J Biol Chem (2014) 0.80
Genome-scale sequencing to identify genes involved in Mendelian disorders. Curr Protoc Hum Genet (2013) 0.80
Phosphodiesterase inhibitors. Part 1: Synthesis and structure-activity relationships of pyrazolopyridine-pyridazinone PDE inhibitors developed from ibudilast. Bioorg Med Chem Lett (2011) 0.79
Chemical informatics uncovers a new role for moexipril as a novel inhibitor of cAMP phosphodiesterase-4 (PDE4). Biochem Pharmacol (2013) 0.79
Candidate tumor suppressor, HCCS-1, is downregulated in human cancers and induces apoptosis in cervical cancer. Int J Cancer (2002) 0.79
Serine phosphorylation of the insulin-like growth factor I (IGF-1) receptor C-terminal tail restrains kinase activity and cell growth. J Biol Chem (2012) 0.79
Stinging nettle dermatitis. Am J Contact Dermat (2003) 0.79
Characterization of the bovine angiotensin converting enzyme promoter: essential roles of Egr-1, ATF-2 and Ets-1 in the regulation by phorbol ester. Gene (2008) 0.78
Upregulation of recepteur d'origine nantais tyrosine kinase and cell invasiveness via early growth response-1 in gastric cancer cells. J Cell Biochem (2012) 0.78
Identification and characterization of small-molecule ligands that maintain pluripotency of human embryonic stem cells. Biochem Soc Trans (2010) 0.77
Irritant contact dermatitis to the brown marmorated stink bug, Halyomorpha halys. Dermatitis (2012) 0.77
Concise routes to pyrazolo[1,5-a]pyridin-3-yl pyridazin-3-ones. Org Biomol Chem (2007) 0.77
Eruptive squamous cell carcinomas with keratoacanthoma-like features in a patient treated with sorafenib. J Drugs Dermatol (2011) 0.77
The Hershey access clinic: a model for improving patient access. J Am Acad Dermatol (2007) 0.77
Synthesis of buprenorphine from oripavine via N-demethylation of oripavine quaternary salts. J Org Chem (2011) 0.77
Phosphodiesterase inhibitors. Part 2: design, synthesis, and structure-activity relationships of dual PDE3/4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory and bronchodilatory activity. Bioorg Med Chem Lett (2011) 0.76
Phosphodiesterase inhibitors. Part 5: hybrid PDE3/4 inhibitors as dual bronchorelaxant/anti-inflammatory agents for inhaled administration. Bioorg Med Chem Lett (2012) 0.76
Diffuse clusters of vesicles on the face and extremities of a 10-month-old girl. Pediatr Dermatol (2010) 0.76
Successful use of adalimumab in treating cutaneous metastatic Crohn's disease: report of a case. Inflamm Bowel Dis (2009) 0.76
Erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells. Biochem J (2010) 0.76
The brown marmorated stinkbug as a new aeroallergen. J Allergy Clin Immunol (2012) 0.76
Phosphodiesterase inhibitors. Part 4: design, synthesis and structure-activity relationships of dual PDE3/4-inhibitory fused bicyclic heteroaromatic-4,4-dimethylpyrazolones. Bioorg Med Chem Lett (2012) 0.76
Etanercept and warts. J Drugs Dermatol (2004) 0.75
A tandem repeat of a fragment of Listeria monocytogenes internalin B protein induces cell survival and proliferation. Am J Physiol Lung Cell Mol Physiol (2010) 0.75
A hitherto unnamed dermatologic entity with clinical features of both psoriasis and eczema. Skinmed (2006) 0.75
Insect repellents and mosquito bites. N Engl J Med (2002) 0.75
Persistent allergic contact dermatitis to plastic toilet seats. Pediatr Dermatol (2011) 0.75
Several generations of chemoenzymatic synthesis of oseltamivir (Tamiflu): evolution of strategy, quest for a process-quality synthesis, and evaluation of efficiency metrics. J Org Chem (2011) 0.75
Methotrexate sodium-associated UV reactivation in a patient with acute lymphoblastic leukemia. Cutis (2012) 0.75
JAAD grand rounds. Increased fragility and bulla formation on the dorsal surface of the hand. J Am Acad Dermatol (2012) 0.75
Serum uric acid levels and hormone therapy type: a retrospective cohort study of postmenopausal women. Menopause (2017) 0.75
Cutaneous cryptococcus in an elderly woman with chronic essential dermatitis. Cutis (2006) 0.75
Medical school and residency influence on choice of an academic career and academic productivity among US neurology faculty. Arch Neurol (2011) 0.75
JAAD grand rounds. Erythematous macules and crusted erosions in sun-exposed areas. J Am Acad Dermatol (2012) 0.75
Treatment of Unstable Distal Clavicle Fractures With Multiple Steinmann Pins-A Modification of Neer's Method: A Series of 56 Consecutive Cases. J Orthop Trauma (2017) 0.75
BURNS and ERUPTS: novel mnemonics for detection of squamous cell carcinoma and basal cell carcinoma. Eur J Dermatol (2010) 0.75
Benzoflavonoids Structure Hinders Human Colon Cancer Clonogenicity. Med Chem (2017) 0.75
Fine wrinkling of the thighs and axillae--quiz case. Middermal elastolysis. Arch Dermatol (2010) 0.75