Published in Mol Genet Metab on September 24, 2011
Cowchock syndrome is associated with a mutation in apoptosis-inducing factor. Am J Hum Genet (2012) 1.30
Exome sequencing improves genetic diagnosis of structural fetal abnormalities revealed by ultrasound. Hum Mol Genet (2014) 1.28
Non-apoptotic functions of apoptosis-regulatory proteins. EMBO Rep (2012) 1.06
Loss of apoptosis-inducing factor critically affects MIA40 function. Cell Death Dis (2015) 0.90
A novel AIFM1 mutation expands the phenotype to an infantile motor neuron disease. Eur J Hum Genet (2015) 0.85
Mitochondrial cytochrome c oxidase deficiency. Clin Sci (Lond) (2016) 0.84
Mutations in apoptosis-inducing factor cause X-linked recessive auditory neuropathy spectrum disorder. J Med Genet (2015) 0.82
Mouse studies to shape clinical trials for mitochondrial diseases: high fat diet in Harlequin mice. PLoS One (2011) 0.81
A slowly progressive mitochondrial encephalomyopathy widens the spectrum of AIFM1 disorders. Neurology (2015) 0.81
Next-generation sequencing for mitochondrial disorders. Br J Pharmacol (2014) 0.80
Neuroglobin gene therapy prevents optic atrophy and preserves durably visual function in Harlequin mice. Mol Ther (2014) 0.78
Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration. Front Neurosci (2016) 0.76
CHCHD4 links AIF to the biogenesis of respiratory chain complex I. Mol Cell Oncol (2015) 0.76
Basal metabolic state governs AIF-dependent growth support in pancreatic cancer cells. BMC Cancer (2016) 0.75
Metabolic epistasis among apoptosis-inducing factor and the mitochondrial import factor CHCHD4. Cell Cycle (2015) 0.75
AIFM1 mutation presenting with fatal encephalomyopathy and mitochondrial disease in an infant. Cold Spring Harb Mol Case Stud (2017) 0.75
Defining NADH-Driven Allostery Regulating Apoptosis-Inducing Factor. Structure (2016) 0.75
The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development (2002) 5.09
Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Genet (2003) 3.91
The initiation of liver development is dependent on Foxa transcription factors. Nature (2005) 3.88
KLF family members regulate intrinsic axon regeneration ability. Science (2009) 3.80
Extracting transcription factor targets from ChIP-Seq data. Nucleic Acids Res (2009) 3.58
Deleterious mutation in the mitochondrial arginyl-transfer RNA synthetase gene is associated with pontocerebellar hypoplasia. Am J Hum Genet (2007) 3.55
Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. Gastroenterology (2002) 3.39
Control of pancreatic β cell regeneration by glucose metabolism. Cell Metab (2011) 3.35
Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology. Nature (2008) 3.23
Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity. Genes Dev (2002) 3.22
The evolution of Fox genes and their role in development and disease. Nat Rev Genet (2009) 3.13
Krüppel-like factor 4 regulates macrophage polarization. J Clin Invest (2011) 3.08
Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells. Gastroenterology (2011) 2.94
Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis. Genome Res (2011) 2.89
Rudimentary horn pregnancy: first-trimester prerupture sonographic diagnosis and confirmation by magnetic resonance imaging. J Ultrasound Med (2005) 2.84
Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development. Proc Natl Acad Sci U S A (2008) 2.55
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. Dev Cell (2009) 2.55
Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach. Gastroenterology (2005) 2.53
Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential. Genes Dev (2011) 2.53
Epigenomic plasticity enables human pancreatic α to β cell reprogramming. J Clin Invest (2013) 2.38
Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev (2008) 2.38
Foxa2 regulates alveolarization and goblet cell hyperplasia. Development (2004) 2.35
The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation. EMBO J (2007) 2.34
Conditional deletion of Krüppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury. Circ Res (2008) 2.30
The H syndrome: a genodermatosis characterized by indurated, hyperpigmented, and hypertrichotic skin with systemic manifestations. J Am Acad Dermatol (2008) 2.29
Glucocorticoid receptor-dependent gene regulatory networks. PLoS Genet (2005) 2.19
The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis. Dev Biol (2004) 2.19
Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. Genes Dev (2011) 2.17
Foxa2 integrates the transcriptional response of the hepatocyte to fasting. Cell Metab (2005) 2.15
Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis. J Biol Chem (2005) 2.15
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell (2009) 2.14
The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity. J Cell Biol (2008) 2.14
Foxa2 is essential for mouse endometrial gland development and fertility. Biol Reprod (2010) 2.12
Defective mitochondrial translation caused by a ribosomal protein (MRPS16) mutation. Ann Neurol (2004) 2.09
Deficiency of the ADP-forming succinyl-CoA synthase activity is associated with encephalomyopathy and mitochondrial DNA depletion. Am J Hum Genet (2005) 2.06
Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer. Cell (2012) 2.05
Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology (2006) 2.04
Foxa2 and H2A.Z mediate nucleosome depletion during embryonic stem cell differentiation. Cell (2012) 2.02
Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs. Am J Hum Genet (2006) 1.97
Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha. Genes Dev (2007) 1.97
MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function. Gastroenterology (2010) 1.95
Mucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferase. Nat Med (2005) 1.93
Foxa2 is required for the differentiation of pancreatic alpha-cells. Dev Biol (2005) 1.90
Elevated mouse hepatic betatrophin expression does not increase human β-cell replication in the transplant setting. Diabetes (2013) 1.90
The transcriptional response of the islet to pregnancy in mice. Mol Endocrinol (2009) 1.89
Pancreatic beta cells require NeuroD to achieve and maintain functional maturity. Cell Metab (2010) 1.88
Mutations in the mitochondrial seryl-tRNA synthetase cause hyperuricemia, pulmonary hypertension, renal failure in infancy and alkalosis, HUPRA syndrome. Am J Hum Genet (2011) 1.86
FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development (2010) 1.86
Foxl1 is a marker of bipotential hepatic progenitor cells in mice. Hepatology (2009) 1.82
Expansion of beta-cell mass in response to pregnancy. Trends Endocrinol Metab (2009) 1.81
Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells. Cell Stem Cell (2013) 1.79
Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage. Hepatology (2007) 1.78
The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion. J Clin Invest (2005) 1.78
Imaging pancreatic beta-cells in the intact pancreas. Am J Physiol Endocrinol Metab (2005) 1.74
Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development. Hepatology (2008) 1.72
Mutations in the fatty acid 2-hydroxylase gene are associated with leukodystrophy with spastic paraparesis and dystonia. Am J Hum Genet (2008) 1.71
Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis. Cancer Res (2007) 1.71
Adaptor protein complex 4 deficiency causes severe autosomal-recessive intellectual disability, progressive spastic paraplegia, shy character, and short stature. Am J Hum Genet (2011) 1.70
The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse. BMC Dev Biol (2009) 1.66
FoxOs function synergistically to promote glucose production. J Biol Chem (2010) 1.66
Foxa2 controls vesicle docking and insulin secretion in mature Beta cells. Cell Metab (2007) 1.66
Defining pancreatic endocrine precursors and their descendants. Diabetes (2007) 1.65
Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells. Mol Cell Biol (2006) 1.63
Acute infantile liver failure due to mutations in the TRMU gene. Am J Hum Genet (2009) 1.61
Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo. Diabetes (2002) 1.60
A study of the clinical and radiological features in a cohort of 93 patients with a COL2A1 mutation causing spondyloepiphyseal dysplasia congenita or a related phenotype. Am J Med Genet A (2015) 1.60
Genetic modulation of PPARgamma phosphorylation regulates insulin sensitivity. Dev Cell (2003) 1.60
Comparison of different labeling methods for two-channel high-density microarray experiments. Physiol Genomics (2002) 1.60
The molecular mechanism underlying Roberts syndrome involves loss of ESCO2 acetyltransferase activity. Hum Mol Genet (2008) 1.58
Resetting the transcription factor network reverses terminal chronic hepatic failure. J Clin Invest (2015) 1.58
An SNX10 mutation causes malignant osteopetrosis of infancy. J Med Genet (2012) 1.58
A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins. Am J Hum Genet (2011) 1.57
Foxa2 is required for transition to air breathing at birth. Proc Natl Acad Sci U S A (2004) 1.57
Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress. Nat Med (2008) 1.57
Foxa2 regulates multiple pathways of insulin secretion. J Clin Invest (2004) 1.57
C6ORF66 is an assembly factor of mitochondrial complex I. Am J Hum Genet (2008) 1.56
Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c. Cell Metab (2011) 1.55
The Thr224Asn mutation in the VPS45 gene is associated with the congenital neutropenia and primary myelofibrosis of infancy. Blood (2013) 1.55
CRTC2 (TORC2) contributes to the transcriptional response to fasting in the liver but is not required for the maintenance of glucose homeostasis. Cell Metab (2009) 1.55