Published in Genes Dev on June 15, 2002
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature (2010) 5.81
On the origin of the beta cell. Genes Dev (2008) 3.34
Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J (2002) 3.30
Generation of functional insulin-producing cells in the gut by Foxo1 ablation. Nat Genet (2012) 2.75
Direct regulation of intestinal fate by Notch. Proc Natl Acad Sci U S A (2005) 2.41
Rfx6 directs islet formation and insulin production in mice and humans. Nature (2010) 2.15
Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation. Genes Dev (2006) 2.15
Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation. Cell Stem Cell (2016) 2.10
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc Natl Acad Sci U S A (2009) 2.09
Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology (2006) 2.04
Insulin gene expression is regulated by DNA methylation. PLoS One (2009) 1.97
The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells. Genes Dev (2006) 1.81
Conserved markers of fetal pancreatic epithelium permit prospective isolation of islet progenitor cells by FACS. Proc Natl Acad Sci U S A (2006) 1.77
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. Nature (2014) 1.77
The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse. BMC Dev Biol (2009) 1.66
SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells. Exp Cell Res (2009) 1.64
Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature (2012) 1.64
Transcriptional control of stem cell maintenance in the Drosophila intestine. Development (2010) 1.48
Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas. Dev Biol (2009) 1.46
Stomach Organ and Cell Lineage Differentiation: from Embryogenesis to Adult Homeostasis. Cell Mol Gastroenterol Hepatol (2016) 1.46
Intestinal development and differentiation. Exp Cell Res (2011) 1.44
Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. Development (2010) 1.43
A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation. Development (2012) 1.39
XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum. Gastroenterology (2010) 1.37
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity. PLoS Genet (2013) 1.37
Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas. Diabetes (2009) 1.33
A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation. PLoS One (2010) 1.33
Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate. Dev Biol (2007) 1.32
Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development. Diabetes (2011) 1.30
Gut endocrine cell development. Mol Cell Endocrinol (2009) 1.29
Identification of a novel putative pancreatic stem/progenitor cell marker DCAMKL-1 in normal mouse pancreas. Am J Physiol Gastrointest Liver Physiol (2010) 1.28
Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice. Gastroenterology (2009) 1.28
Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine. Dev Biol (2007) 1.27
FGF10 signaling controls stomach morphogenesis. Dev Biol (2006) 1.23
Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a. Proc Natl Acad Sci U S A (2010) 1.19
Convergence of the insulin and serotonin programs in the pancreatic β-cell. Diabetes (2011) 1.18
Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival. J Clin Invest (2010) 1.18
Deconstructing pancreas development to reconstruct human islets from pluripotent stem cells. Cell Stem Cell (2010) 1.13
Development of the Drosophila entero-endocrine lineage and its specification by the Notch signaling pathway. Dev Biol (2011) 1.07
Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Dev Biol (2007) 1.06
Neonatal diabetes and congenital malabsorptive diarrhea attributable to a novel mutation in the human neurogenin-3 gene coding sequence. J Clin Endocrinol Metab (2011) 1.05
Loss of genes implicated in gastric function during platypus evolution. Genome Biol (2008) 1.02
Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development. BMC Dev Biol (2009) 1.02
A stem cell marker-expressing subset of enteroendocrine cells resides at the crypt base in the small intestine. Am J Physiol Gastrointest Liver Physiol (2010) 1.01
Serotonin and GI Disorders: An Update on Clinical and Experimental Studies. Clin Transl Gastroenterol (2012) 1.01
Clusters of conserved beta cell marker genes for assessment of beta cell phenotype. PLoS One (2011) 1.01
Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev (2009) 1.00
Notch signaling regulates gastric antral LGR5 stem cell function. EMBO J (2015) 0.99
Arx is required for normal enteroendocrine cell development in mice and humans. Dev Biol (2012) 0.98
Generation of L cells in mouse and human small intestine organoids. Diabetes (2013) 0.98
The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas. Diabetes (2015) 0.98
Enteroendocrine cells: neglected players in gastrointestinal disorders? Therap Adv Gastroenterol (2008) 0.98
Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells. Gastroenterology (2008) 0.98
Basic helix-loop-helix transcription factors and enteroendocrine cell differentiation. Diabetes Obes Metab (2011) 0.96
Requirement of the tissue-restricted homeodomain transcription factor Nkx6.3 in differentiation of gastrin-producing G cells in the stomach antrum. Mol Cell Biol (2008) 0.94
Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification. EMBO J (2014) 0.94
The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and β-cell differentiation. Development (2012) 0.93
Enteroendocrine precursors differentiate independently of Wnt and form serotonin expressing adenomas in response to active beta-catenin. Proc Natl Acad Sci U S A (2007) 0.93
Transcriptional control of spermatogonial maintenance and differentiation. Semin Cell Dev Biol (2014) 0.93
Stem cells and lineages of the intestine: a developmental and evolutionary perspective. Dev Genes Evol (2012) 0.93
Organoid Models of Human Gastrointestinal Development and Disease. Gastroenterology (2016) 0.92
NEUROG3 is a critical downstream effector for STAT3-regulated differentiation of mammalian stem and progenitor spermatogonia. Biol Reprod (2012) 0.92
Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function. Diabetes (2015) 0.91
Epithelial tyrosine phosphatase SHP-2 protects against intestinal inflammation in mice. Mol Cell Biol (2013) 0.91
Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease. Alzheimers Res Ther (2010) 0.91
Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine. Dev Biol (2012) 0.91
Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish. BMC Biol (2013) 0.90
The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice. PLoS One (2012) 0.90
The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration. Development (2011) 0.90
Competence of failed endocrine progenitors to give rise to acinar but not ductal cells is restricted to early pancreas development. Dev Biol (2011) 0.90
Cell cycle-dependent differentiation dynamics balances growth and endocrine differentiation in the pancreas. PLoS Biol (2015) 0.89
Targeting development of incretin-producing cells increases insulin secretion. J Clin Invest (2014) 0.88
An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development. PLoS Genet (2014) 0.87
Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells. Genes Dev (2016) 0.87
FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures. Nat Commun (2014) 0.87
Distinct cellular origins for serotonin-expressing and enterochromaffin-like cells in the gastric corpus. Gastroenterology (2013) 0.85
Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas. PLoS One (2013) 0.84
hnRNP I inhibits Notch signaling and regulates intestinal epithelial homeostasis in the zebrafish. PLoS Genet (2009) 0.84
Regulation of mouse intestinal L cell progenitors proliferation by the glucagon family of peptides. Endocrinology (2012) 0.84
The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression. Dev Biol (2007) 0.83
A gutsy task: generating intestinal tissue from human pluripotent stem cells. Dig Dis Sci (2013) 0.83
Conserved genetic pathways controlling the development of the diffuse endocrine system in vertebrates and Drosophila. Gen Comp Endocrinol (2009) 0.83
Dicer1 is required to repress neuronal fate during endocrine cell maturation. Diabetes (2013) 0.82
A quantitative assay for insulin-expressing colony-forming progenitors. J Vis Exp (2011) 0.82
The Peutz-Jeghers kinase LKB1 suppresses polyp growth from intestinal cells of a proglucagon-expressing lineage in mice. Dis Model Mech (2014) 0.81
A mouse model for monitoring islet cell genesis and developing therapies for diabetes. Dis Model Mech (2010) 0.81
Contribution of a non-β-cell source to β-cell mass during pregnancy. PLoS One (2014) 0.81
Role of indigenous lactobacilli in gastrin-mediated acid production in the mouse stomach. Appl Environ Microbiol (2011) 0.80
Role of microRNAs in islet beta-cell compensation and failure during diabetes. J Diabetes Res (2014) 0.80
The Myb-p300-CREB axis modulates intestine homeostasis, radiosensitivity and tumorigenesis. Cell Death Dis (2013) 0.79
Dissecting Human Gene Functions Regulating Islet Development With Targeted Gene Transduction. Diabetes (2015) 0.79
Grg3/TLE3 and Grg1/TLE1 induce monohormonal pancreatic β-cells while repressing α-cell functions. Diabetes (2014) 0.79
A CRM1-mediated nuclear export signal is essential for cytoplasmic localization of neurogenin 3 in neurons. PLoS One (2013) 0.79
Expression analysis of the Islet-1 gene in the developing and adult gastrointestinal tract. Gene Expr Patterns (2011) 0.79
The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation. Development (2016) 0.78
Notch regulation of gastrointestinal stem cells. J Physiol (2016) 0.78
Angiotensin II receptor expression and relation to Helicobacter pylori-infection in the stomach of the Mongolian gerbil. BMC Gastroenterol (2010) 0.78
Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cell subtypes. World J Gastroenterol (2012) 0.77
Stomach development, stem cells and disease. Development (2016) 0.77
Tales from the crypts: regulatory peptides and cytokines in gastrointestinal homeostasis and disease. J Clin Invest (2007) 0.76
Notch signaling: cell fate control and signal integration in development. Science (1999) 28.83
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell (1993) 10.35
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A (2000) 8.34
Control of endodermal endocrine development by Hes-1. Nat Genet (2000) 7.71
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science (2001) 7.17
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev (1997) 5.66
The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins. J Cell Biol (1993) 4.18
Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. Gastroenterology (2002) 3.39
neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS. Mol Cell Neurosci (1996) 3.18
Biochemical characteristics of caspases-3, -6, -7, and -8. J Biol Chem (1997) 3.04
Differentiation and self-renewal in the mouse gastrointestinal epithelium. Curr Opin Cell Biol (1994) 2.51
Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4(-/-) embryos. Development (1997) 2.41
Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. Mol Cell Biol (2000) 2.34
An achaete-scute homologue essential for neuroendocrine differentiation in the lung. Nature (1997) 2.29
Transgenic mice containing intestinal fatty acid-binding protein-human growth hormone fusion genes exhibit correct regional and cell-specific expression of the reporter gene in their small intestine. Proc Natl Acad Sci U S A (1988) 2.12
Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication. Curr Biol (1994) 2.03
Female mouse germ cells form synchronously dividing cysts. Development (1998) 1.96
Lectins are sensitive tools for defining the differentiation programs of mouse gut epithelial cell lineages. Am J Physiol (1994) 1.67
Coordinated localisation of mucins and trefoil peptides in the ulcer associated cell lineage and the gastrointestinal mucosa. Gut (2000) 1.59
Gastrin deficiency results in altered gastric differentiation and decreased colonic proliferation in mice. Gastroenterology (1997) 1.45
Gastrointestinal expression and partial cDNA cloning of murine Muc2. Am J Physiol (1999) 1.41
The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex. Development (1997) 1.38
Use of transgenic mice to study regulation of gene expression in the parietal cell lineage of gastric units. J Biol Chem (1993) 1.35
Functional genomics of the endocrine pancreas: the pancreas clone set and PancChip, new resources for diabetes research. Diabetes (2002) 1.23
Extracellular matrix components and integrins in relationship to human intestinal epithelial cell differentiation. Prog Histochem Cytochem (1997) 1.17
Getting to the guts of enteroendocrine differentiation. Nat Genet (2000) 1.10
Structure and expression of murine intestinal trefoil factor: high evolutionary conservation and postnatal expression. Biochem Biophys Res Commun (1995) 1.06
Ultrastructural analysis of the organization and distribution of insulin receptors on the surface of 3T3-L1 adipocytes: rapid microaggregation and migration of occupied receptors. J Cell Physiol (1985) 0.98
Cell-specific processing of chromogranin A in endocrine cells of the rat stomach. J Histochem Cytochem (2001) 0.98
The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development (2002) 5.09
Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Genet (2003) 3.91
The initiation of liver development is dependent on Foxa transcription factors. Nature (2005) 3.88
KLF family members regulate intrinsic axon regeneration ability. Science (2009) 3.80
Extracting transcription factor targets from ChIP-Seq data. Nucleic Acids Res (2009) 3.58
Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. Gastroenterology (2002) 3.39
Control of pancreatic β cell regeneration by glucose metabolism. Cell Metab (2011) 3.35
Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology. Nature (2008) 3.23
The evolution of Fox genes and their role in development and disease. Nat Rev Genet (2009) 3.13
Krüppel-like factor 4 regulates macrophage polarization. J Clin Invest (2011) 3.08
Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells. Gastroenterology (2011) 2.94
Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development. Proc Natl Acad Sci U S A (2008) 2.55
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. Dev Cell (2009) 2.55
Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach. Gastroenterology (2005) 2.53
Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential. Genes Dev (2011) 2.53
Epigenomic plasticity enables human pancreatic α to β cell reprogramming. J Clin Invest (2013) 2.38
Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev (2008) 2.38
Foxa2 regulates alveolarization and goblet cell hyperplasia. Development (2004) 2.35
The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation. EMBO J (2007) 2.34
Conditional deletion of Krüppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury. Circ Res (2008) 2.30
Glucocorticoid receptor-dependent gene regulatory networks. PLoS Genet (2005) 2.19
The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis. Dev Biol (2004) 2.19
Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. Genes Dev (2011) 2.17
Foxa2 integrates the transcriptional response of the hepatocyte to fasting. Cell Metab (2005) 2.15
Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis. J Biol Chem (2005) 2.15
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell (2009) 2.14
The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity. J Cell Biol (2008) 2.14
Foxa2 is essential for mouse endometrial gland development and fertility. Biol Reprod (2010) 2.12
Bone morphogenetic protein signaling is essential for terminal differentiation of the intestinal secretory cell lineage. Gastroenterology (2007) 2.07
Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer. Cell (2012) 2.05
Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology (2006) 2.04
Foxa2 and H2A.Z mediate nucleosome depletion during embryonic stem cell differentiation. Cell (2012) 2.02
Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha. Genes Dev (2007) 1.97
MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function. Gastroenterology (2010) 1.95
Elevated mouse hepatic betatrophin expression does not increase human β-cell replication in the transplant setting. Diabetes (2013) 1.90
Foxa2 is required for the differentiation of pancreatic alpha-cells. Dev Biol (2005) 1.90
The transcriptional response of the islet to pregnancy in mice. Mol Endocrinol (2009) 1.89
Pancreatic beta cells require NeuroD to achieve and maintain functional maturity. Cell Metab (2010) 1.88
FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development (2010) 1.86
Foxl1 is a marker of bipotential hepatic progenitor cells in mice. Hepatology (2009) 1.82
Expansion of beta-cell mass in response to pregnancy. Trends Endocrinol Metab (2009) 1.81
Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells. Cell Stem Cell (2013) 1.79
Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage. Hepatology (2007) 1.78
The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion. J Clin Invest (2005) 1.78
Imaging pancreatic beta-cells in the intact pancreas. Am J Physiol Endocrinol Metab (2005) 1.74
Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development. Hepatology (2008) 1.72
Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis. Cancer Res (2007) 1.71
The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse. BMC Dev Biol (2009) 1.66
FoxOs function synergistically to promote glucose production. J Biol Chem (2010) 1.66
Foxa2 controls vesicle docking and insulin secretion in mature Beta cells. Cell Metab (2007) 1.66
Defining pancreatic endocrine precursors and their descendants. Diabetes (2007) 1.65
Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells. Mol Cell Biol (2006) 1.63
Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo. Diabetes (2002) 1.60
Genetic modulation of PPARgamma phosphorylation regulates insulin sensitivity. Dev Cell (2003) 1.60
Comparison of different labeling methods for two-channel high-density microarray experiments. Physiol Genomics (2002) 1.60
Resetting the transcription factor network reverses terminal chronic hepatic failure. J Clin Invest (2015) 1.58
Foxa2 is required for transition to air breathing at birth. Proc Natl Acad Sci U S A (2004) 1.57
Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress. Nat Med (2008) 1.57
Foxa2 regulates multiple pathways of insulin secretion. J Clin Invest (2004) 1.57
Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c. Cell Metab (2011) 1.55
CRTC2 (TORC2) contributes to the transcriptional response to fasting in the liver but is not required for the maintenance of glucose homeostasis. Cell Metab (2009) 1.55
The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice. J Clin Invest (2009) 1.54
Genome-wide analysis of histone modifications in human pancreatic islets. Genome Res (2010) 1.51
An FGF response pathway that mediates hepatic gene induction in embryonic endoderm cells. Dev Cell (2006) 1.50
Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development. J Clin Invest (2009) 1.50
The nucleosome map of the mammalian liver. Nat Struct Mol Biol (2011) 1.47
Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell. Mol Endocrinol (2010) 1.47
Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling. J Clin Invest (2011) 1.46
Orthogonal analysis of C/EBPbeta targets in vivo during liver proliferation. Proc Natl Acad Sci U S A (2004) 1.46
Cis-regulatory modules in the mammalian liver: composition depends on strength of Foxa2 consensus site. Nucleic Acids Res (2008) 1.46
Identification of transcriptional networks during liver regeneration. J Biol Chem (2004) 1.46
beta-Catenin is critical for early postnatal liver growth. Am J Physiol Gastrointest Liver Physiol (2007) 1.45
Transcriptional networks in the liver: hepatocyte nuclear factor 6 function is largely independent of Foxa2. Mol Cell Biol (2005) 1.45
FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine. J Biol Chem (2008) 1.44
Foxa1 and Foxa2 regulate bile duct development in mice. J Clin Invest (2009) 1.43
Regeneration of pancreatic islets after partial pancreatectomy in mice does not involve the reactivation of neurogenin-3. Diabetes (2005) 1.38
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity. PLoS Genet (2013) 1.37
Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development. Dev Biol (2009) 1.36
HNF-4alpha: from MODY to late-onset type 2 diabetes. Trends Mol Med (2004) 1.32
Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia. Gastroenterology (2009) 1.31
Liver-specific ablation of integrin-linked kinase in mice results in abnormal histology, enhanced cell proliferation, and hepatomegaly. Hepatology (2008) 1.31
DNA methylation is required for the control of stem cell differentiation in the small intestine. Genes Dev (2014) 1.31
Gut endocrine cell development. Mol Cell Endocrinol (2009) 1.29
The homeobox gene Hhex is essential for proper hepatoblast differentiation and bile duct morphogenesis. Dev Biol (2007) 1.29
Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice. Gastroenterology (2009) 1.28
Species-specific strategies underlying conserved functions of metabolic transcription factors. Mol Endocrinol (2011) 1.25
Transcriptional program of the endocrine pancreas in mice and humans. Diabetes (2003) 1.23
Functional genomics of the endocrine pancreas: the pancreas clone set and PancChip, new resources for diabetes research. Diabetes (2002) 1.23
Forkhead transcription factors II. Cell (2007) 1.21
Activation of Wnt/beta-catenin pathway during hepatocyte growth factor-induced hepatomegaly in mice. Hepatology (2006) 1.21
Cdx2 regulates endo-lysosomal function and epithelial cell polarity. Genes Dev (2010) 1.21