Published in Am J Clin Nutr on September 01, 1990
Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci U S A (1993) 13.27
Vitamin E and respiratory tract infections in elderly nursing home residents: a randomized controlled trial. JAMA (2004) 2.27
Anti-inflammatory properties of alpha- and gamma-tocopherol. Mol Aspects Med (2007) 1.31
Age-associated changes in immune and inflammatory responses: impact of vitamin E intervention. J Leukoc Biol (2008) 1.19
Vitamin E exhibits bone anabolic actions in normal male rats. J Bone Miner Metab (2009) 1.10
Antioxidants in cystic fibrosis. Conclusions from the CF antioxidant workshop, Bethesda, Maryland, November 11-12, 2003. Free Radic Biol Med (2006) 1.06
Genome-wide association studies identified three independent polymorphisms associated with α-tocopherol content in maize kernels. PLoS One (2012) 1.04
Modulation of Immune Functions by Foods. Evid Based Complement Alternat Med (2004) 1.01
The role of nutrition in enhancing immunity in aging. Aging Dis (2011) 0.99
Does melatonin protect or treat brain damage from traumatic oxidative stress? Exp Brain Res (2005) 0.89
Potential role of dietary lipids in the prophylaxis of some clinical conditions. Arch Med Sci (2015) 0.83
Supplementation of elderly Japanese men and women with fucoidan from seaweed increases immune responses to seasonal influenza vaccination. J Nutr (2013) 0.82
Vitamin E reverses impaired linker for activation of T cells activation in T cells from aged C57BL/6 mice. J Nutr (2009) 0.81
Effect of vitamin E on aspirin-induced gastric mucosal injury in rats. Dig Dis Sci (2000) 0.80
Combination of physical activity, nutrition, or other metabolic factors and vaccine response. Front Biosci (2007) 0.80
Polymorphisms at cytokine genes may determine the effect of vitamin E on cytokine production in the elderly. J Nutr (2009) 0.79
Role of micronutrients in skin health and function. Biomol Ther (Seoul) (2015) 0.79
IL-2 and IL-10 gene polymorphisms are associated with respiratory tract infection and may modulate the effect of vitamin E on lower respiratory tract infections in elderly nursing home residents. Am J Clin Nutr (2010) 0.78
Cytokine response to vitamin E supplementation is dependent on pre-supplementation cytokine levels. Biofactors (2008) 0.78
Development of Selectable Marker-Free Transgenic Rice Plants with Enhanced Seed Tocopherol Content through FLP/FRT-Mediated Spontaneous Auto-Excision. PLoS One (2015) 0.77
Micronutrient status, immune response and infectious disease in elderly of less developed countries. Sight Life Mag (2009) 0.76
Effects of vitamin e on bone biomechanical and histomorphometric parameters in ovariectomized rats. J Osteoporos (2013) 0.76
Micronutrients and dengue. Am J Trop Med Hyg (2014) 0.76
Vitamin E treatment for children with chronic hepatitis B: a randomized placebo controlled trial. World J Gastroenterol (2008) 0.76
Amino acid and vitamin supplementation improved health conditions in elderly participants. J Clin Biochem Nutr (2011) 0.75
Nutritional Considerations for Healthy Aging and Reduction in Age-Related Chronic Disease. Adv Nutr (2017) 0.75
Vitamin E prevents oxidative modification of brain and lymphocyte band 3 proteins during aging. Proc Natl Acad Sci U S A (1996) 0.75
Putrescine treatment reverses α-tocopherol-induced desynchronization of polyamine and retinoid metabolism during rat liver regeneration. J Transl Med (2016) 0.75
Vitamin E supplementation of elderly people. Am J Clin Nutr (1991) 0.75
Immunomodulatory basis of antioxidant therapy and its future prospects: an appraisal. Inflammopharmacology (2017) 0.75
Nutrient requirements of suspension cultures of soybean root cells. Exp Cell Res (1968) 30.19
An interlingua for electronic interchange of medical information: using frames to map between clinical vocabularies. Comput Biomed Res (1991) 15.50
Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med (2001) 14.48
Physicians' information needs: analysis of questions posed during clinical teaching. Ann Intern Med (1991) 12.10
Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J Exp Med (1986) 10.91
Internist-1, an experimental computer-based diagnostic consultant for general internal medicine. N Engl J Med (1982) 10.87
Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat Genet (1994) 10.14
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc Natl Acad Sci U S A (1994) 8.47
Expanding the concept of medical information: an observational study of physicians' information needs. Comput Biomed Res (1992) 7.74
Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base. Pharmacogenomics J (2001) 5.94
Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci U S A (2000) 5.49
The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N Engl J Med (1989) 5.02
Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. Nat Med (1999) 4.44
Connexins regulate calcium signaling by controlling ATP release. Proc Natl Acad Sci U S A (1998) 4.35
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc Natl Acad Sci U S A (2001) 4.30
Diet, serum cholesterol, and death from coronary heart disease. The Western Electric study. N Engl J Med (1981) 4.01
The basis for using the Internet to support the information needs of primary care. J Am Med Inform Assoc (1999) 3.95
A computer-assisted medical diagnostic consultation service. Implementation and prospective evaluation of a prototype. Ann Intern Med (1989) 3.93
An experiment comparing lexical and statistical methods for extracting MeSH terms from clinical free text. J Am Med Inform Assoc (1998) 3.79
Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody. N Engl J Med (1982) 3.78
Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial. JAMA (1997) 3.68
Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro. J Immunol (1987) 3.61
The INTERNIST-1/QUICK MEDICAL REFERENCE project--status report. West J Med (1986) 3.53
A new approach to the implementation of direct care-provider order entry. Proc AMIA Annu Fall Symp (1996) 3.45
Weight change and diabetes incidence: findings from a national cohort of US adults. Am J Epidemiol (1997) 3.32
Prospective study of adult onset diabetes mellitus (type 2) and risk of colorectal cancer in women. J Natl Cancer Inst (1999) 3.22
Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadate. J Biol Chem (1997) 3.20
Evaluating evaluations of medical diagnostic systems. J Am Med Inform Assoc (1997) 3.15
The physical map of the chromosome of a serogroup A strain of Neisseria meningitidis shows complex rearrangements relative to the chromosomes of the two mapped strains of the closely related species N. gonorrhoeae. J Bacteriol (1995) 3.10
Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancer. Development (1991) 3.03
Physical activity and risk for cardiovascular events in diabetic women. Ann Intern Med (2001) 3.01
Gap-junction-mediated propagation and amplification of cell injury. Nat Neurosci (1998) 3.01
Extending the lifespan of long-lived mice. Nature (2001) 2.98
Frequencies of IL-2- and IL-4-secreting T cells in naive and antigen-stimulated lymphocyte populations. J Immunol (1988) 2.94
Diet and risk of Type II diabetes: the role of types of fat and carbohydrate. Diabetologia (2001) 2.91
A dose-response study of antibiotic resistance in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother (2000) 2.91
Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science (2000) 2.90
Immunochemical characterization of a protein associated with Mycobacterium leprae cell wall. Infect Immun (1985) 2.88
Empirical derivation of an electronic clinically useful problem statement system. Ann Intern Med (1999) 2.83
Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects. Circulation (2005) 2.77
Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumors. N Engl J Med (1992) 2.73
The impact of diabetes mellitus on mortality from all causes and coronary heart disease in women: 20 years of follow-up. Arch Intern Med (2001) 2.67
Monoclonal antibody that recognizes an outer membrane antigen common to the pathogenic Neisseria species but not to most nonpathogenic Neisseria species. Infect Immun (1984) 2.65
The genetics of the gonococcus. Annu Rev Microbiol (1984) 2.63
A candidate gene approach to searching for low-penetrance breast and prostate cancer genes. Nat Rev Cancer (2005) 2.62
A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes. J Physiol (1997) 2.60
Transfer of Streptococcus adjacens and Streptococcus defectivus to Abiotrophia gen. nov. as Abiotrophia adiacens comb. nov. and Abiotrophia defectiva comb. nov., respectively. Int J Syst Bacteriol (1995) 2.55
HIV-1 induces phenotypic and functional perturbations of B cells in chronically infected individuals. Proc Natl Acad Sci U S A (2001) 2.54
Integration and beyond: linking information from disparate sources and into workflow. J Am Med Inform Assoc (2000) 2.51
MicroRNA profile analysis of human prostate cancers. Cancer Gene Ther (2008) 2.43
DNA solution of the maximal clique problem. Science (1997) 2.43
Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia. Nat Immunol (2001) 2.42
Phase variation of gonococcal protein II: regulation of gene expression by slipped-strand mispairing of a repetitive DNA sequence. Cell (1989) 2.42
Tumour necrosis factor production in Falciparum malaria and its association with schizont rupture. Clin Exp Immunol (1989) 2.41
Recombinant soluble CD4 therapy in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. A phase I-II escalating dosage trial. Ann Intern Med (1990) 2.40
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia (2011) 2.37
The transferrin receptor expressed by gonococcal strain FA1090 is required for the experimental infection of human male volunteers. Mol Microbiol (1998) 2.33
Rhythmic auditory stimulation in gait training for Parkinson's disease patients. Mov Disord (1996) 2.31
Heuristic determination of quantitative data for knowledge acquisition in medicine. Comput Biomed Res (1991) 2.29
Recombination among protein II genes of Neisseria gonorrhoeae generates new coding sequences and increases structural variability in the protein II family. Mol Microbiol (1988) 2.26
Inorganic polyphosphate in Escherichia coli: the phosphate regulon and the stringent response. J Bacteriol (1998) 2.21
Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins. J Biol Chem (1998) 2.19
Multiple biological activities of human recombinant interleukin 1. J Clin Invest (1986) 2.16
Design of aging intervention studies: the NIA interventions testing program. Age (Dordr) (2008) 2.14
A phase I/II trial of iodine-131-tositumomab (anti-CD20), etoposide, cyclophosphamide, and autologous stem cell transplantation for relapsed B-cell lymphomas. Blood (2000) 2.11
Urological day case surgery in elderly and medically unfit patients using sedoanalgesia: what are the limits? Br J Urol (1995) 2.10
Monoclonal antibodies against Neisseria gonorrhoeae: production of antibodies directed against a strain-specific cell surface antigen. Infect Immun (1981) 2.09
Multiple organ carcinogenicity of 1,3-butadiene in B6C3F1 mice after 60 weeks of inhalation exposure. Science (1985) 2.09
Changes in intake of fruits and vegetables in relation to risk of obesity and weight gain among middle-aged women. Int J Obes Relat Metab Disord (2004) 2.09
HbA1c measured in stored erythrocytes and mortality rate among middle-aged and older women. Diabetologia (2007) 2.03
Preliminary experience of endoscopic submucosal tunnel dissection for upper gastrointestinal submucosal tumors. Endoscopy (2012) 2.02
Rheumatoid cachexia: cytokine-driven hypermetabolism accompanying reduced body cell mass in chronic inflammation. J Clin Invest (1994) 2.01
Evaluation of long-term maintenance of a large medical knowledge base. J Am Med Inform Assoc (1996) 2.00
INTERNIST-1/CADUCEUS: problems facing expert consultant programs. Methods Inf Med (1984) 1.99
Distributing knowledge maintenance for clinical decision-support systems: the "knowledge library" model. Proc AMIA Symp (1999) 1.98
Intracerebral bacillary angiomatosis in a patient infected with human immunodeficiency virus. Ann Intern Med (1992) 1.96
Pgp-1hi T lymphocytes accumulate with age in mice and respond poorly to concanavalin A. Eur J Immunol (1989) 1.95
Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation. Oncogene (2012) 1.95
New concepts on the pathogenesis of fever. Rev Infect Dis (1988) 1.94
Multiple gonococcal pilin antigenic variants are produced during experimental human infections. J Clin Invest (1994) 1.93
Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries. Am J Physiol (1993) 1.92
A clinical trial of anti-idiotype therapy for B cell malignancy. Blood (1985) 1.91
Phase and antigenic variation of pili and outer membrane protein II of Neisseria gonorrhoeae. J Infect Dis (1986) 1.90
Human experimentation with Neisseria gonorrhoeae: rationale, methods, and implications for the biology of infection and vaccine development. J Infect Dis (1994) 1.88
Comparison of maternal and infant outcomes between vacuum extraction and forceps deliveries. Am J Epidemiol (2001) 1.84
Characterization of Neisseria gonorrhoeae protein II phase variation by use of monoclonal antibodies. Infect Immun (1984) 1.83
Plasma sex steroid hormones and risk of developing type 2 diabetes in women: a prospective study. Diabetologia (2007) 1.80
Multiple gonococcal opacity proteins are expressed during experimental urethral infection in the male. J Exp Med (1994) 1.80
Genetic locus (nmp-1) affecting the principal outer membrane protein of Neisseria gonorrhoeae. J Bacteriol (1980) 1.80
B cells of HIV-1-infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells. J Exp Med (2000) 1.79
Mycobacterium avium-M. intracellulare isolates from patients with or without acquired immunodeficiency syndrome. Antimicrob Agents Chemother (1986) 1.79
Patients with active Crohn's disease have elevated serum antibodies to antigens of seven enteric bacterial pathogens. Gastroenterology (1984) 1.79
Prevalence of mental disorder in military children and adolescents: findings from a two-stage community survey. J Am Acad Child Adolesc Psychiatry (1995) 1.78
A meta-analysis of case-control studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma in China. Br J Cancer (2005) 1.76
Response of cutaneous T cell lymphoma to therapy with hybridoma monoclonal antibody. Lancet (1981) 1.76
Preparing librarians to meet the challenges of today's health care environment. J Am Med Inform Assoc (1997) 1.76
Dietary vitamin A and risk of cancer in the Western Electric study. Lancet (1981) 1.74
In vitro production of IL 1 beta, IL 1 alpha, TNF and IL2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation. Eur J Immunol (1989) 1.73