The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair.

PubWeight™: 1.23‹?› | Rank: Top 10%

🔗 View Article (PMID 22037168)

Published in Mol Cell Endocrinol on October 20, 2011

Authors

David M de Kretser1, Robyn E O'Hehir, Charles L Hardy, Mark P Hedger

Author Affiliations

1: Monash Institute of Medical Research and the Department of Immunology and Pathology, Monash University, Clayton Victoria 3800, Australia. david.de.kretser@monash.edu

Articles citing this

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination. Nat Neurosci (2013) 3.59

Circulating angiogenic factors associated with response and survival in patients with acute graft-versus-host disease: results from Blood and Marrow Transplant Clinical Trials Network 0302 and 0802. Biol Blood Marrow Transplant (2015) 1.13

Fibroblast growth factor 2 drives changes in gene expression following injury to murine cartilage in vitro and in vivo. Arthritis Rheum (2013) 0.87

Transforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding. J Biol Chem (2016) 0.87

Activin, neutrophils, and inflammation: just coincidence? Semin Immunopathol (2013) 0.85

Cytosolic phospholipase A(2)α and eicosanoids regulate expression of genes in macrophages involved in host defense and inflammation. PLoS One (2013) 0.85

Follistatin is induced by ionizing radiation and potentially predictive of radiosensitivity in radiation-induced fibrosis patient derived fibroblasts. PLoS One (2013) 0.84

Impaired resolution of inflammation in the Endoglin heterozygous mouse model of chronic colitis. Mediators Inflamm (2014) 0.83

A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients. PLoS One (2016) 0.82

The activin A antagonist follistatin inhibits cystic fibrosis-like lung inflammation and pathology. Immunol Cell Biol (2015) 0.81

Differential transcription of fathead minnow immune-related genes following infection with frog virus 3, an emerging pathogen of ectothermic vertebrates. Virology (2014) 0.81

The Role of Activin A and B and the Benefit of Follistatin Treatment in Renal Ischemia-Reperfusion Injury in Mice. Transplant Direct (2016) 0.80

The immunoregulatory and fibrotic roles of activin A in allergic asthma. Clin Exp Allergy (2015) 0.80

Alveolar macrophages of GM-CSF knockout mice exhibit mixed M1 and M2 phenotypes. BMC Immunol (2013) 0.79

CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy. Osteoarthritis Cartilage (2016) 0.78

Loss of BMPR2 leads to high bone mass due to increased osteoblast activity. J Cell Sci (2015) 0.78

Upregulation of activin-B and follistatin in pulmonary fibrosis - a translational study using human biopsies and a specific inhibitor in mouse fibrosis models. BMC Pulm Med (2014) 0.78

Differential Expression and Release of Activin A and Follistatin in Chronic Rhinosinusitis with and without Nasal Polyps. PLoS One (2015) 0.78

Serum Levels of Follistatin Are Positively Associated With Serum-Free Thyroxine Levels in Patients With Hyperthyroidism or Euthyroidism. Medicine (Baltimore) (2016) 0.78

Late acute graft versus host disease: a prospective analysis of clinical outcomes and circulating angiogenic factors. Blood (2016) 0.78

Activin A expression in esophageal carcinoma and its association with tumor aggressiveness and differentiation. Oncol Lett (2015) 0.77

The nutrigenomic investigation of C57BL/6N mice fed a short-term high-fat diet highlights early changes in clock genes expression. Genes Nutr (2013) 0.76

Indications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells. Hum Mol Genet (2014) 0.75

Substantial Increases Occur in Serum Activins and Follistatin during Lung Transplantation. PLoS One (2016) 0.75

Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration. MOJ Proteom Bioinform (2015) 0.75

Follistatin and the Breast Implant Capsule. Plast Reconstr Surg Glob Open (2017) 0.75

Gram-negative bacterial lipopolysaccharide stimulates activin a secretion from human amniotic epithelial cells. Int J Endocrinol (2013) 0.75

Activin A Stimulates Aromatase via the ALK4-Smad Pathway in Endometriosis. Biomed Res Int (2016) 0.75

Circulating activin-A is elevated in postmenopausal women with low bone mass: the three-month effect of zoledronic acid treatment. Osteoporos Int (2012) 0.75

Articles by these authors

Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis. Proc Natl Acad Sci U S A (2005) 2.56

Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia. Proc Natl Acad Sci U S A (2007) 1.62

Peripheral lung function in patients with stable and unstable asthma. J Allergy Clin Immunol (2013) 1.50

Immunological, paracrine and endocrine aspects of testicular immune privilege. Mol Cell Endocrinol (2010) 1.31

Activin and related proteins in inflammation: not just interested bystanders. Cytokine Growth Factor Rev (2009) 1.23

Allergen-related approaches to immunotherapy. Pharmacol Ther (2008) 1.02

Rat resident testicular macrophages have an alternatively activated phenotype and constitutively produce interleukin-10 in vitro. J Leukoc Biol (2011) 0.99

Allergic rhinitis and its impact on asthma update (ARIA 2008)--western and Asian-Pacific perspective. Asian Pac J Allergy Immunol (2009) 0.99

Ara h 2 peptides containing dominant CD4+ T-cell epitopes: candidates for a peanut allergy therapeutic. J Allergy Clin Immunol (2010) 0.98

The effector T cell response to ryegrass pollen is counterregulated by simultaneous induction of regulatory T cells. J Immunol (2010) 0.98

ADAM33 haplotypes are associated with asthma in a large Australian population. Eur J Hum Genet (2006) 0.97

Inflammatory networks in the control of spermatogenesis : chronic inflammation in an immunologically privileged tissue? Adv Exp Med Biol (2008) 0.96

The activin A antagonist follistatin inhibits asthmatic airway remodelling. Thorax (2012) 0.94

The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis. Endocrinology (2004) 0.94

Functional regulatory T cells and allergen immunotherapy. Curr Opin Allergy Clin Immunol (2010) 0.91

The testis and epididymis are productively infected by SIV and SHIV in juvenile macaques during the post-acute stage of infection. Retrovirology (2007) 0.90

The peanut allergy epidemic: allergen molecular characterisation and prospects for specific therapy. Expert Rev Mol Med (2007) 0.90

Toll-like receptors in the gonads and reproductive tract: emerging roles in reproductive physiology and pathology. Immunol Cell Biol (2007) 0.90

T cell reactivity during infectious mononucleosis and persistent gammaherpesvirus infection in mice. J Immunol (2004) 0.88

Potential food allergens in wine: double-blind, placebo-controlled trial and basophil activation analysis. Nutrition (2006) 0.87

A diagnostic test for scabies: IgE specificity for a recombinant allergen of Sarcoptes scabiei. Diagn Microbiol Infect Dis (2011) 0.87

Glucocorticoid receptor deficient thymic and peripheral T cells develop normally in adult mice. Eur J Immunol (2002) 0.86

The signalling imprints of nanoparticle uptake by bone marrow derived dendritic cells. Methods (2013) 0.86

A stereological analysis of the response of spermatogenesis to an acute inflammatory episode in adult rats. J Androl (2006) 0.85

IgE Reactivity of Blue Swimmer Crab (Portunus pelagicus) Tropomyosin, Por p 1, and Other Allergens; Cross-Reactivity with Black Tiger Prawn and Effects of Heating. PLoS One (2013) 0.85

Promising particle-based vaccines in cancer therapy. Expert Rev Vaccines (2008) 0.85

Acute regulation of activin A and its binding protein, follistatin, in serum and tissues following lipopolysaccharide treatment of adult male mice. Am J Physiol Regul Integr Comp Physiol (2012) 0.84

Differential responses of epithelial Sertoli cells of the rat testis to Toll-like receptor 2 and 4 ligands: implications for studies of testicular inflammation using bacterial lipopolysaccharides. Innate Immun (2009) 0.84

Interleukin-13 regulates secretion of the tumor growth factor-{beta} superfamily cytokine activin A in allergic airway inflammation. Am J Respir Cell Mol Biol (2009) 0.83

Tumour necrosis factor-α stimulates human neutrophils to release preformed activin A. Immunol Cell Biol (2011) 0.83

Differential uptake of nanoparticles and microparticles by pulmonary APC subsets induces discrete immunological imprints. J Immunol (2013) 0.83

Use of animal models to investigate major allergens associated with food allergy. J Allergy (Cairo) (2013) 0.82

TLR ligands of ryegrass pollen microbial contaminants enhance Th1 and Th2 responses and decrease induction of Foxp3(hi) regulatory T cells. Eur J Immunol (2013) 0.82

Epididymitis: revelations at the convergence of clinical and basic sciences. Asian J Androl (2015) 0.82

Induction of allergic responses to peanut allergen in sheep. PLoS One (2012) 0.82

The response of testicular leukocytes to lipopolysaccharide-induced inflammation: further evidence for heterogeneity of the testicular macrophage population. Cell Tissue Res (2002) 0.82

Cytokine profiles in the testes of rats treated with lipopolysaccharide reveal localized suppression of inflammatory responses. Am J Physiol Regul Integr Comp Physiol (2005) 0.82

Oligoclonal analysis of the atopic T cell response to the group 1 allergen of Cynodon dactylon (bermuda grass) pollen: pre- and post-allergen-specific immunotherapy. Int Arch Allergy Immunol (2002) 0.81

Characterization and de novo sequencing of snow crab tropomyosin enzymatic peptides by both electrospray ionization and matrix-assisted laser desorption ionization QqToF tandem mass spectrometry. J Mass Spectrom (2010) 0.81

Correlation between blood activin levels and clinical parameters of type 2 diabetes. Exp Diabetes Res (2012) 0.81

Molecular identification of lyso-glycerophosphocholines as endogenous immunosuppressives in bovine and rat gonadal fluids. Biol Reprod (2008) 0.81

Galectin-10, a potential biomarker of eosinophilic airway inflammation. PLoS One (2012) 0.81

Effects of chronic celecoxib on testicular function in normal and lipopolysaccharide-treated rats. Int J Androl (2008) 0.81

Phenotypic and functional heterogeneity of the testicular macrophage population: a new regulatory model. J Reprod Immunol (2013) 0.81

'You have to learn to live with it': a qualitative and quantitative study of older people with asthma. Clin Respir J (2007) 0.81

Inert 50-nm polystyrene nanoparticles that modify pulmonary dendritic cell function and inhibit allergic airway inflammation. J Immunol (2011) 0.81

Characterization of a mouse model of allergy to a major occupational latex glove allergen Hev b 5. Am J Respir Crit Care Med (2003) 0.80

Effect of heat processing on antibody reactivity to allergen variants and fragments of black tiger prawn: A comprehensive allergenomic approach. Mol Nutr Food Res (2014) 0.80

Unique and cross-reactive T cell epitope peptides of the major Bahia grass pollen allergen, Pas n 1. Int Arch Allergy Immunol (2012) 0.80

Expression patterns of activin, inhibin and follistatin variants in the adult male mouse reproductive tract suggest important roles in the epididymis and vas deferens. Reprod Fertil Dev (2013) 0.79

1. Diagnosis, treatment and prevention of allergic disease: the basics. Med J Aust (2006) 0.79

Novel use of rituximab in a case of Riedel's thyroiditis refractory to glucocorticoids and tamoxifen. J Clin Endocrinol Metab (2013) 0.79

High dose allergen stimulation of T cells from house dust mite-allergic subjects induces expansion of IFN-gamma+ T Cells, apoptosis of CD4+IL-4+ T cells and T cell anergy. Int Arch Allergy Immunol (2003) 0.79

Molecular aspects of male fertility. International Workshop on Molecular Andrology. EMBO Rep (2009) 0.79

Serum activin A and B, and follistatin in critically ill patients with influenza A(H1N1) infection. BMC Infect Dis (2014) 0.79

Characterisation of macaque testicular leucocyte populations and T-lymphocyte immunity. J Reprod Immunol (2013) 0.78

Regulation of activin A release from murine bone marrow-derived neutrophil precursors by tumour necrosis factor-α and insulin. Cytokine (2012) 0.78

Constitutive expression of prostaglandin-endoperoxide synthase 2 by somatic and spermatogenic cells is responsible for prostaglandin E2 production in the adult rat testis. Biol Reprod (2007) 0.78

Current developments for improving efficacy of allergy vaccines. Expert Rev Vaccines (2015) 0.78

What's in a kiss: peanut allergen transmission as a sensitizer? J Allergy Clin Immunol (2006) 0.78

Clinical allergy to hazelnut and peanut: identification of T cell cross-reactive allergens. Int Arch Allergy Immunol (2011) 0.77

Molecular cloning and characterization of hazel pollen protein (70 kD) as a luminal binding protein (BiP): a novel cross-reactive plant allergen. Int Arch Allergy Immunol (2003) 0.77

Tolerance to wheat in whole-grain cereal biscuit in wheat-allergic children. J Allergy Clin Immunol (2012) 0.77

Identification of a novel apolipoprotein, ApoN, in ovarian follicular fluid. Endocrinology (2004) 0.77

Improving general practice consultations for older people with asthma: a cluster randomised control trial. Med J Aust (2009) 0.77

Specific and sensitive enzyme-linked immunosorbent assays for analysis of residual allergenic food proteins in commercial bottled wine fined with egg white, milk, and nongrape-derived tannins. J Agric Food Chem (2007) 0.77

The dominant 55 kDa allergen of the subtropical Bahia grass (Paspalum notatum) pollen is a group 13 pollen allergen, Pas n 13. Mol Immunol (2011) 0.77

Prevention of diabetes-induced albuminuria in transgenic rats overexpressing human aldose reductase. Endocrine (2002) 0.77

Pattern of activin A and follistatin release in a sheep model of cardiopulmonary bypass. Cytokine (2011) 0.77

Molecular cloning, expression and immunological characterisation of Pas n 1, the major allergen of Bahia grass Paspalum notatum pollen. Mol Immunol (2008) 0.77

The relationship between immunosuppressive activity and immunoregulatory cytokines in seminal plasma: influence of sperm autoimmunity and seminal leukocytes. J Reprod Immunol (2006) 0.76

The latex allergen hev B 5 is an antigen with repetitive murine B-cell epitopes. Int Arch Allergy Immunol (2004) 0.76

Murine Inhibin α-Subunit Haploinsufficiency Causes Transient Abnormalities in Prepubertal Testis Development Followed by Adult Testicular Decline. Endocrinology (2015) 0.76

Anaphylaxis to lemon soap: citrus seed and peanut allergen cross-reactivity. Ann Allergy Asthma Immunol (2007) 0.76

Regulation of Sertoli cell activin A and inhibin B by tumour necrosis factor α and interleukin 1α: interaction with follicle-stimulating hormone/adenosine 3',5'-cyclic phosphate signalling. Mol Cell Endocrinol (2011) 0.76

Adrenaline and non-life threatening allergic reactions: Intramuscular adrenaline is safe. BMJ (2003) 0.75

ACEI associated angioedema. Aust Fam Physician (2012) 0.75

Food allergy in adults. Aust Fam Physician (2008) 0.75

Risk-minimisation strategies for peanut allergy. Lancet (2007) 0.75

Purification of the major group 1 allergen from Bahia grass pollen, Pas n 1. Int Arch Allergy Immunol (2010) 0.75

Special issue on severe asthma. Clin Exp Allergy (2012) 0.75

Intractable shellfish anaphylaxis: sensitization by cross-reactive substances in a complementary "immune stimulant" and acrylic nails. Ann Allergy Asthma Immunol (2013) 0.75

Advances in development of hypoallergenic latex immunotherapy. Curr Opin Allergy Clin Immunol (2005) 0.75

T cell targeted strategies for improved efficacy and safety of specific immunotherapy for allergic disease. Antiinflamm Antiallergy Agents Med Chem (2013) 0.75

The effects of engineered nanoparticles on pulmonary immune homeostasis. Drug Metab Rev (2013) 0.75