Published in J Clin Endocrinol Metab on November 02, 2011
Magnetic Resonance & Optical Spectroscopy Validation | NCT01827527
Low macrophage accumulation in skeletal muscle of obese type 2 diabetics and elderly subjects. Obesity (Silver Spring) (2012) 1.62
Mitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trials. Int J Biochem Cell Biol (2013) 1.38
Skeletal muscle mitochondria and aging: a review. J Aging Res (2012) 1.27
What do magnetic resonance-based measurements of Pi→ATP flux tell us about skeletal muscle metabolism? Diabetes (2012) 1.02
Appendicular skeletal muscle mass and insulin resistance in an elderly korean population: the korean social life, health and aging project-health examination cohort. Diabetes Metab J (2015) 0.98
Mitochondrial dysfunction in aging: Much progress but many unresolved questions. Biochim Biophys Acta (2015) 0.94
Skeletal muscle mitochondrial H2 O2 emission increases with immobilization and decreases after aerobic training in young and older men. J Physiol (2015) 0.93
Reduced skeletal muscle oxidative capacity and elevated ceramide but not diacylglycerol content in severe obesity. Obesity (Silver Spring) (2013) 0.93
Insulin sensitivity and metabolic flexibility following exercise training among different obese insulin-resistant phenotypes. Am J Physiol Endocrinol Metab (2013) 0.89
Greater Skeletal Muscle Fat Infiltration Is Associated With Higher All-Cause and Cardiovascular Mortality in Older Men. J Gerontol A Biol Sci Med Sci (2015) 0.83
Mitochondrial genetic variants identified to be associated with BMI in adults. PLoS One (2014) 0.83
Perilipin 3 Differentially Regulates Skeletal Muscle Lipid Oxidation in Active, Sedentary, and Type 2 Diabetic Males. J Clin Endocrinol Metab (2015) 0.82
Adipose triglyceride lipase decrement affects skeletal muscle homeostasis during aging through FAs-PPARα-PGC-1α antioxidant response. Oncotarget (2016) 0.78
Age affects the contraction-induced mitochondrial redox response in skeletal muscle. Front Physiol (2015) 0.78
Commonality versus specificity among adiposity traits in normal-weight and moderately overweight adults. Int J Obes (Lond) (2013) 0.76
'Adipaging': ageing and obesity share biological hallmarks related to a dysfunctional adipose tissue. J Physiol (2016) 0.75
Protein Requirements during Aging. Nutrients (2016) 0.75
Mitochondrial-Targeted Antioxidant Maintains Blood Flow, Mitochondrial Function, and Redox Balance in Old Mice Following Prolonged Limb Ischemia. Int J Mol Sci (2017) 0.75
Intermuscular Adipose Tissue Content and Intramyocellular Lipid Fatty Acid Saturation Are Associated with Glucose Homeostasis in Middle-Aged and Older Adults. Endocrinol Metab (Seoul) (2017) 0.75
Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care (1999) 26.39
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab (2005) 13.91
Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science (2003) 11.39
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci U S A (2007) 8.23
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia (1999) 8.17
Java-based graphical user interface for the MRUI quantitation package. MAGMA (2001) 5.78
Percutaneous needle biopsy of skeletal muscle in physiological and clinical research. Scand J Clin Lab Invest (1975) 4.67
Adipose tissue in muscle: a novel depot similar in size to visceral adipose tissue. Am J Clin Nutr (2005) 3.40
Insulin resistance as a predictor of age-related diseases. J Clin Endocrinol Metab (2001) 3.31
Age-related changes in total and regional fat distribution. Ageing Res Rev (2009) 2.88
Uncoupling to survive? The role of mitochondrial inefficiency in ageing. Exp Gerontol (2000) 2.71
Accuracy of armband monitors for measuring daily energy expenditure in healthy adults. Med Sci Sports Exerc (2010) 2.65
Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis. Cell Metab (2007) 2.64
Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle. Proc Natl Acad Sci U S A (1996) 2.52
AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome. Nat Rev Drug Discov (2004) 2.46
Oxidative capacity and ageing in human muscle. J Physiol (2000) 2.44
Separate measures of ATP utilization and recovery in human skeletal muscle. J Physiol (1993) 2.13
Mitochondrial membrane potential and aging. Aging Cell (2004) 2.12
Type II skeletal myofibers possess unique properties that potentiate mitochondrial H(2)O(2) generation. Am J Physiol Cell Physiol (2005) 2.08
The free radical theory of aging. Antioxid Redox Signal (2003) 2.04
Activation of glycolysis in human muscle in vivo. Am J Physiol (1997) 1.93
Mild mitochondrial uncoupling impacts cellular aging in human muscles in vivo. Proc Natl Acad Sci U S A (2007) 1.86
Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function. Diabetes (2009) 1.82
Magnetic resonance imaging provides new insights into the characterization of adipose and lean tissue distribution. Can J Physiol Pharmacol (1996) 1.50
Age-related muscle dysfunction. Exp Gerontol (2008) 1.46
Reduced mitochondrial coupling in vivo alters cellular energetics in aged mouse skeletal muscle. J Physiol (2005) 1.43
Large energetic adaptations of elderly muscle to resistance and endurance training. J Appl Physiol (1985) (2001) 1.43
Mitochondrial function in vivo: spectroscopy provides window on cellular energetics. Methods (2008) 1.40
PGC-1alpha in aging and anti-aging interventions. Biochim Biophys Acta (2009) 1.35
Diversity in levels of intracellular total creatine and triglycerides in human skeletal muscles observed by (1)H-MRS. J Appl Physiol (1985) (1999) 1.24
Influence of endurance running and recovery diet on intramyocellular lipid content in women: a 1H NMR study. Am J Physiol Endocrinol Metab (2002) 1.24
Skeletal muscle mitochondrial capacity and insulin resistance in type 2 diabetes. J Clin Endocrinol Metab (2011) 1.14
Quantification of dinor, dihydro metabolites of F2-isoprostanes in urine by liquid chromatography/tandem mass spectrometry. Anal Biochem (2005) 1.08
Individual variation in contractile cost and recovery in a human skeletal muscle. Proc Natl Acad Sci U S A (1993) 1.04
Peroxynitrite and brain mitochondria: evidence for increased proton leak. J Neurochem (1998) 1.02
Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates. N Engl J Med (2009) 12.38
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med (2011) 8.00
The human serum metabolome. PLoS One (2011) 5.55
Effect of dietary protein content on weight gain, energy expenditure, and body composition during overeating: a randomized controlled trial. JAMA (2012) 4.30
Calorie restriction increases muscle mitochondrial biogenesis in healthy humans. PLoS Med (2007) 3.92
A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle. Diabetes (2005) 3.84
A guide to analysis of mouse energy metabolism. Nat Methods (2011) 3.82
Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response. Diabetes (2008) 3.80
Total body skeletal muscle and adipose tissue volumes: estimation from a single abdominal cross-sectional image. J Appl Physiol (1985) (2004) 3.59
Increased food energy supply is more than sufficient to explain the US epidemic of obesity. Am J Clin Nutr (2009) 3.59
Is it time to change the way we report and discuss weight loss? Obesity (Silver Spring) (2009) 3.57
Estimating the changes in energy flux that characterize the rise in obesity prevalence. Am J Clin Nutr (2009) 3.56
Racial differences in abdominal depot-specific adiposity in white and African American adults. Am J Clin Nutr (2009) 3.39
Lateral hypothalamic area deep brain stimulation for refractory obesity: a pilot study with preliminary data on safety, body weight, and energy metabolism. J Neurosurg (2013) 3.31
Calorie restriction and aging: review of the literature and implications for studies in humans. Am J Clin Nutr (2003) 3.11
Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight. J Clin Invest (2005) 3.10
Total-body skeletal muscle mass: estimation by a new dual-energy X-ray absorptiometry method. Am J Clin Nutr (2002) 2.96
Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects. Diabetes Care (2006) 2.86
Comparisons of waist circumferences measured at 4 sites. Am J Clin Nutr (2003) 2.78
Sarcopenic obesity predicts instrumental activities of daily living disability in the elderly. Obes Res (2004) 2.76
Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo. Diabetes (2005) 2.76
Independent association of insulin resistance with larger amounts of intermuscular adipose tissue and a greater acute insulin response to glucose in African American than in white nondiabetic women. Am J Clin Nutr (2005) 2.72
Visceral adipose tissue: relations between single-slice areas and total volume. Am J Clin Nutr (2004) 2.57
Metabolic and behavioral compensations in response to caloric restriction: implications for the maintenance of weight loss. PLoS One (2009) 2.56
Sarcopenia and increased adipose tissue infiltration of muscle in elderly African American women. Am J Clin Nutr (2004) 2.48
The relationship of waist circumference and BMI to visceral, subcutaneous, and total body fat: sex and race differences. Obesity (Silver Spring) (2010) 2.47
Increased fat intake, impaired fat oxidation, and failure of fat cell proliferation result in ectopic fat storage, insulin resistance, and type 2 diabetes mellitus. Ann N Y Acad Sci (2002) 2.46
Validation study of energy expenditure and intake during calorie restriction using doubly labeled water and changes in body composition. Am J Clin Nutr (2007) 2.33
Effect of calorie restriction with or without exercise on body composition and fat distribution. J Clin Endocrinol Metab (2007) 2.33
Estimating the effects of energy imbalance on changes in body weight in children. Am J Clin Nutr (2006) 2.21
Defining insulin resistance from hyperinsulinemic-euglycemic clamps. Diabetes Care (2012) 2.21
A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans. Am J Clin Nutr (2006) 2.12
Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility. Cell Metab (2012) 2.11
Dynamic changes in fat oxidation in human primary myocytes mirror metabolic characteristics of the donor. J Clin Invest (2005) 2.10
Role of adiponectin in human skeletal muscle bioenergetics. Cell Metab (2006) 2.09
Assessment methods in human body composition. Curr Opin Clin Nutr Metab Care (2008) 2.09
Effect of calorie restriction on resting metabolic rate and spontaneous physical activity. Obesity (Silver Spring) (2007) 2.06
Profiles of sedentary behavior in children and adolescents: the US National Health and Nutrition Examination Survey, 2001-2006. Int J Pediatr Obes (2009) 2.05
Metabolic flexibility and insulin resistance. Am J Physiol Endocrinol Metab (2008) 2.02
Is percentage body fat differentially related to body mass index in Hispanic Americans, African Americans, and European Americans? Am J Clin Nutr (2003) 2.01
Waist circumference correlates with metabolic syndrome indicators better than percentage fat. Obesity (Silver Spring) (2006) 2.00
A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trial. J Clin Endocrinol Metab (2011) 1.98
Effects of 4 weight-loss diets differing in fat, protein, and carbohydrate on fat mass, lean mass, visceral adipose tissue, and hepatic fat: results from the POUNDS LOST trial. Am J Clin Nutr (2012) 1.96
Effects of traditional and western environments on prevalence of type 2 diabetes in Pima Indians in Mexico and the U.S. Diabetes Care (2006) 1.96
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake. Cell Metab (2008) 1.94
Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism. Biochem J (2004) 1.89
Mild mitochondrial uncoupling impacts cellular aging in human muscles in vivo. Proc Natl Acad Sci U S A (2007) 1.86
Body-size dependence of resting energy expenditure can be attributed to nonenergetic homogeneity of fat-free mass. Am J Physiol Endocrinol Metab (2002) 1.82
Design and conduct of the CALERIE study: comprehensive assessment of the long-term effects of reducing intake of energy. J Gerontol A Biol Sci Med Sci (2010) 1.80
Scaling of human body composition to stature: new insights into body mass index. Am J Clin Nutr (2007) 1.79
Self-report-based estimates of energy intake offer an inadequate basis for scientific conclusions. Am J Clin Nutr (2013) 1.79
miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol (2010) 1.75
Ten nights of moderate hypoxia improves insulin sensitivity in obese humans. Diabetes Care (2013) 1.75
Family history of diabetes links impaired substrate switching and reduced mitochondrial content in skeletal muscle. Diabetes (2007) 1.74
Measurement of dietary restraint: validity tests of four questionnaires. Appetite (2006) 1.72
Dual-energy X-ray performs as well as clinical computed tomography for the measurement of visceral fat. Obesity (Silver Spring) (2012) 1.71
Leisure time sedentary behavior, occupational/domestic physical activity, and metabolic syndrome in U.S. men and women. Metab Syndr Relat Disord (2009) 1.71
Comparison of visceral adipose tissue mass in adult African Americans and whites. Obes Res (2005) 1.71
Smaller organ mass with greater age, except for heart. J Appl Physiol (1985) (2009) 1.70
Adipose tissue collagen VI in obesity. J Clin Endocrinol Metab (2009) 1.70
Glucose tolerance and skeletal muscle gene expression in response to alternate day fasting. Obes Res (2005) 1.69
Human mesenchymal stem cells as an in vitro model for human adipogenesis. Obes Res (2003) 1.68
Neuroimaging and obesity: mapping the brain responses to hunger and satiation in humans using positron emission tomography. Ann N Y Acad Sci (2002) 1.66
Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study. Obesity (Silver Spring) (2012) 1.66
Effect of 6-month calorie restriction and exercise on serum and liver lipids and markers of liver function. Obesity (Silver Spring) (2008) 1.64
Sex differences in human adipose tissues - the biology of pear shape. Biol Sex Differ (2012) 1.64
Obesity and type 2 diabetes: what can be unified and what needs to be individualized? J Clin Endocrinol Metab (2011) 1.63
Comparison of dual-energy X-ray absorptiometry and magnetic resonance imaging-measured adipose tissue depots in HIV-infected and control subjects. Am J Clin Nutr (2008) 1.63
Low macrophage accumulation in skeletal muscle of obese type 2 diabetics and elderly subjects. Obesity (Silver Spring) (2012) 1.62
Isolation of human adipose-derived stem cells from biopsies and liposuction specimens. Methods Mol Biol (2008) 1.62
Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals. Atherosclerosis (2008) 1.58
Determinants of intramyocellular triglyceride turnover: implications for insulin sensitivity. Am J Physiol Endocrinol Metab (2007) 1.57
Intermuscular adipose tissue-free skeletal muscle mass: estimation by dual-energy X-ray absorptiometry in adults. J Appl Physiol (1985) (2004) 1.57
Lactic acidosis in vivo: testing the link between lactate generation and H+ accumulation in ischemic mouse muscle. J Appl Physiol (1985) (2010) 1.54
Enhanced weight loss with pramlintide/metreleptin: an integrated neurohormonal approach to obesity pharmacotherapy. Obesity (Silver Spring) (2009) 1.51
Sex and race differences in fat distribution among Asian, African-American, and Caucasian prepubertal children. J Clin Endocrinol Metab (2002) 1.51
Muscle-associated triglyceride measured by computed tomography and magnetic resonance spectroscopy. Obesity (Silver Spring) (2006) 1.49
Improved diabetic control in advanced heart failure patients treated with left ventricular assist devices. Eur J Heart Fail (2010) 1.49
Predicting fat percent by skinfolds in racial groups: Durnin and Womersley revisited. Med Sci Sports Exerc (2011) 1.48
Total-body skeletal muscle mass: estimation by dual-energy X-ray absorptiometry in children and adolescents. Am J Clin Nutr (2006) 1.48
Volume estimates by imaging methods: model comparisons with visible woman as the reference. Obes Res (2003) 1.46