Published in Cancer Res on November 09, 2011
Mechanisms of resistance to endocrine therapy in breast cancer: focus on signaling pathways, miRNAs and genetically based resistance. Int J Mol Sci (2012) 1.44
Nuclear receptor coactivators: master regulators of human health and disease. Annu Rev Med (2013) 1.22
The function of steroid receptor coactivator-1 in normal tissues and cancer. Int J Biol Sci (2012) 1.00
hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3. Cancer Cell Int (2014) 0.89
NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis. Cancer Res (2014) 0.87
Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma. Oncotarget (2015) 0.84
The ADAMs family of proteases as targets for the treatment of cancer. Cancer Biol Ther (2016) 0.77
Genomic interaction between ER and HMGB2 identifies DDX18 as a novel driver of endocrine resistance in breast cancer cells. Oncogene (2014) 0.76
ADAM23 is downregulated in side population and suppresses lung metastasis of lung carcinoma cells. Cancer Sci (2016) 0.75
S100β as a serum marker in endocrine resistant breast cancer. BMC Med (2017) 0.75
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol (2009) 235.12
Bioconductor: open software development for computational biology and bioinformatics. Genome Biol (2004) 143.19
Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol (2004) 101.91
Model-based analysis of ChIP-Seq (MACS). Genome Biol (2008) 51.63
A map of recent positive selection in the human genome. PLoS Biol (2006) 29.19
Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics (2006) 22.61
Preprocessing of oligonucleotide array data. Nat Biotechnol (2004) 4.70
MYB function in normal and cancer cells. Nat Rev Cancer (2008) 3.56
Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission. Science (2006) 3.52
Characterization of genome-wide p53-binding sites upon stress response. Nucleic Acids Res (2008) 2.67
Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation. Proc Natl Acad Sci U S A (2008) 1.62
LGI1, a putative tumor metastasis suppressor gene, controls in vitro invasiveness and expression of matrix metalloproteinases in glioma cells through the ERK1/2 pathway. J Biol Chem (2004) 1.62
Steroid receptor coactivator (SRC) family: masters of systems biology. J Biol Chem (2010) 1.57
Changes in estrogen receptor, progesterone receptor and Her-2/neu status with time: discordance rates between primary and metastatic breast cancer. Anticancer Res (2009) 1.50
The steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis. Cancer Res (2009) 1.48
Coassociation of estrogen receptor and p160 proteins predicts resistance to endocrine treatment; SRC-1 is an independent predictor of breast cancer recurrence. Clin Cancer Res (2009) 1.38
Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer. Clin Cancer Res (2005) 1.38
Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu. J Biol Chem (2004) 1.35
Role of ADAMs in cancer formation and progression. Clin Cancer Res (2009) 1.29
Selection and characterization of a breast cancer cell line resistant to the antiestrogen LY 117018. Endocrinology (1985) 1.20
Global characterization of transcriptional impact of the SRC-3 coregulator. Mol Endocrinol (2010) 1.14
Ets-2 and p160 proteins collaborate to regulate c-Myc in endocrine resistant breast cancer. Oncogene (2007) 1.10
Steroid receptor coactivator-1 upregulates integrin α₅ expression to promote breast cancer cell adhesion and migration. Cancer Res (2011) 1.08
Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain. Biochem J (1998) 1.03
Interaction of developmental transcription factor HOXC11 with steroid receptor coactivator SRC-1 mediates resistance to endocrine therapy in breast cancer [corrected]. Cancer Res (2010) 1.00
ADAM proteins in the brain. J Clin Neurosci (2004) 0.94
It's all in the details: methods in breast development and cancer. Breast Cancer Res (2009) 0.87
Cyclooxygenase-2 predicts adverse effects of tamoxifen: a possible mechanism of role for nuclear HER2 in breast cancer patients. Endocr Relat Cancer (2008) 0.86
Increased expression of LGI1 gene triggers growth inhibition and apoptosis of neuroblastoma cells. J Cell Physiol (2006) 0.83
ADAM22 plays an important role in cell adhesion and spreading with the assistance of 14-3-3. Biochem Biophys Res Commun (2005) 0.82
Biological characterization of ADAM22 variants reveals the importance of a disintegrin domain sequence in cell surface expression. J Recept Signal Transduct Res (2010) 0.79
Expression of LGI1 Impairs Proliferation and Survival of HeLa Cells. Int J Cell Biol (2009) 0.77
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol (2008) 23.93
Brivanib versus sorafenib as first-line therapy in patients with unresectable, advanced hepatocellular carcinoma: results from the randomized phase III BRISK-FL study. J Clin Oncol (2013) 3.45
Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science (2008) 3.17
Apatinib for chemotherapy-refractory advanced metastatic gastric cancer: results from a randomized, placebo-controlled, parallel-arm, phase II trial. J Clin Oncol (2013) 2.69
An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response. Mol Cell (2007) 2.57
Evaluating a surrogate endpoint at three levels, with application to vaccine development. Stat Med (2008) 2.50
Sunitinib versus sorafenib in advanced hepatocellular cancer: results of a randomized phase III trial. J Clin Oncol (2013) 2.46
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol (2002) 2.45
A wireless passive pressure microsensor fabricated in HTCC MEMS technology for harsh environments. Sensors (Basel) (2013) 2.44
Evidence of dysregulation of dendritic cells in primary HIV infection. Blood (2010) 2.39
AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice. Cancer Res (2004) 2.07
Estimation of the initial viral growth rate and basic reproductive number during acute HIV-1 infection. J Virol (2010) 2.02
Association of functional variations in COMT and GCH1 genes with postherniotomy pain and related impairment. Pain (2015) 2.01
Characterizing the risk assessment of heavy metals and sampling uncertainty analysis in paddy field by geostatistics and GIS. Environ Pollut (2005) 2.00
Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms. Cell Res (2011) 1.99
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Res (2013) 1.92
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Mol Cell Biol (2008) 1.75
Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design. J Virol (2008) 1.69
A predictive model for the detection of tumor lysis syndrome during AML induction therapy. Leuk Lymphoma (2006) 1.67
Phase 1 safety and immunogenicity testing of DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles. J Infect Dis (2011) 1.67
Predictive value of breast lesions of "uncertain malignant potential" and "suspicious for malignancy" determined by needle core biopsy. Ann Surg Oncol (2006) 1.66
Informal caregiver burden among survivors of prolonged mechanical ventilation. Am J Respir Crit Care Med (2006) 1.64
Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation. Proc Natl Acad Sci U S A (2008) 1.62
Surgical e-learning: validation of multimedia web-based lectures. Med Educ (2007) 1.61
Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis. Cancer Res (2005) 1.60
A multinational study of thromboprophylaxis practice in critically ill children. Crit Care Med (2014) 1.56
The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis. Cell Res (2010) 1.56
Mitochondrial localization of telomeric protein TIN2 links telomere regulation to metabolic control. Mol Cell (2012) 1.55
In vivo activation of PPAR target genes by RXR homodimers. EMBO J (2004) 1.53
The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice. Cancer Res (2008) 1.53
Delayed build-up of Arctic ice sheets during 400,000-year minima in insolation variability. Nature (2012) 1.53
Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. J Clin Invest (2015) 1.53
Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis. Cancer Res (2011) 1.49
The steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis. Cancer Res (2009) 1.48
Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: subset analyses of the phase III Sorafenib Asia-Pacific trial. Eur J Cancer (2012) 1.45
Factor VIII May Predict Catheter-Related Thrombosis in Critically Ill Children: A Preliminary Study. Pediatr Crit Care Med (2015) 1.44
Coordinated reset has sustained aftereffects in Parkinsonian monkeys. Ann Neurol (2012) 1.42
Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. J Steroid Biochem Mol Biol (2002) 1.42
A threshold method for immunological correlates of protection. BMC Med Res Methodol (2013) 1.41
Bevacizumab plus capecitabine and cisplatin in Chinese patients with inoperable locally advanced or metastatic gastric or gastroesophageal junction cancer: randomized, double-blind, phase III study (AVATAR study). Gastric Cancer (2014) 1.41
Jmjd1a demethylase-regulated histone modification is essential for cAMP-response element modulator-regulated gene expression and spermatogenesis. J Biol Chem (2009) 1.38
Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer. Clin Cancer Res (2005) 1.38
Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ. Hum Mol Genet (2010) 1.38
Coassociation of estrogen receptor and p160 proteins predicts resistance to endocrine treatment; SRC-1 is an independent predictor of breast cancer recurrence. Clin Cancer Res (2009) 1.38
Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness. Cancer Res (2011) 1.36
Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo. Mol Cell Biol (2005) 1.36
Weight gain prevention among women. Obesity (Silver Spring) (2007) 1.36
Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults. Hum Mol Genet (2010) 1.35
Human health risk assessment of heavy metals in soil-vegetable system: a multi-medium analysis. Sci Total Environ (2013) 1.33
Deletion of the cancer-amplified coactivator AIB3 results in defective placentation and embryonic lethality. J Biol Chem (2002) 1.30
Heavy metal sources identification and sampling uncertainty analysis in a field-scale vegetable soil of Hangzhou, China. Environ Pollut (2008) 1.29
Differential recruitment of coregulator proteins steroid receptor coactivator-1 and silencing mediator for retinoid and thyroid receptors to the estrogen receptor-estrogen response element by beta-estradiol and 4-hydroxytamoxifen in human breast cancer. J Clin Endocrinol Metab (2004) 1.29
Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. Endocrinology (2003) 1.28
Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort. Diabetes (2008) 1.26
Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol (2005) 1.25
Vascular injuries after blunt chest trauma: diagnosis and management. Scand J Trauma Resusc Emerg Med (2009) 1.25
Liver-specific overexpression of the insulin-like growth factor-I enhances somatic growth and partially prevents the effects of growth hormone deficiency. Endocrinology (2006) 1.25
FK506-binding protein 52 is essential to uterine reproductive physiology controlled by the progesterone receptor A isoform. Mol Endocrinol (2006) 1.25
Heavy metal contaminations in a soil-rice system: identification of spatial dependence in relation to soil properties of paddy fields. J Hazard Mater (2010) 1.24
SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells. J Neurosci (2003) 1.24
Stimulation of steroid receptor coactivator-3 (SRC-3) gene overexpression by a positive regulatory loop of E2F1 and SRC-3. Mol Endocrinol (2006) 1.19
Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction. Proc Natl Acad Sci U S A (2004) 1.19
Genetic ablation of the amplified-in-breast cancer 1 inhibits spontaneous prostate cancer progression in mice. Cancer Res (2007) 1.18
Factors affecting successful breast conservation for ductal carcinoma in situ. Ann Surg Oncol (2007) 1.18
Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland. Proc Natl Acad Sci U S A (2006) 1.17
Steroid receptor coactivator 3 maintains circulating insulin-like growth factor I (IGF-I) by controlling IGF-binding protein 3 expression. Mol Cell Biol (2008) 1.17
Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection. PLoS Pathog (2010) 1.16
Steroid receptor coactivator-3 is required for inhibition of neointima formation by estrogen. Circulation (2002) 1.14
Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology. Proc Natl Acad Sci U S A (2010) 1.14
Growth factor-dependent regulation of survivin by c-myc in human breast cancer. J Mol Endocrinol (2006) 1.13
Safety and immunogenicity of an HIV adenoviral vector boost after DNA plasmid vaccine prime by route of administration: a randomized clinical trial. PLoS One (2011) 1.13
The amino Acid residues at positions 120 to 123 are crucial for the antigenicity of hepatitis B surface antigen. J Clin Microbiol (2007) 1.12
Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells. Mol Cell Biol (2008) 1.11
The coactivator SRC-1 is an essential coordinator of hepatic glucose production. Cell Metab (2010) 1.11
L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain. Neurobiol Dis (2005) 1.10
Synergy of human immunodeficiency virus protease inhibitors with chloroquine against Plasmodium falciparum in vitro and Plasmodium chabaudi in vivo. Antimicrob Agents Chemother (2008) 1.09
Steroid receptor coactivator-1 upregulates integrin α₅ expression to promote breast cancer cell adhesion and migration. Cancer Res (2011) 1.08
Comparison of ENCODE region SNPs between Cebu Filipino and Asian HapMap samples. J Hum Genet (2007) 1.08
Landfill site selection using spatial information technologies and AHP: a case study in Beijing, China. J Environ Manage (2009) 1.08
Application of 16S rDNA-PCR amplification and DGGE fingerprinting for detection of shift in microbial community diversity in Cu-, Zn-, and Cd-contaminated paddy soils. Chemosphere (2005) 1.06
Generation of CD34+ cells from CCR5-disrupted human embryonic and induced pluripotent stem cells. Hum Gene Ther (2011) 1.05
Tissue- and nuclear receptor-specific function of the C-terminal LXXLL motif of coactivator NCoA6/AIB3 in mice. Mol Cell Biol (2007) 1.05
Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia. Proc Natl Acad Sci U S A (2010) 1.05
Unintended pregnancy influences racial disparity in tubal sterilization rates. J Gen Intern Med (2009) 1.04
Coactivators in PPAR-Regulated Gene Expression. PPAR Res (2010) 1.04
Vertically aligned boron nitride nanosheets: chemical vapor synthesis, ultraviolet light emission, and superhydrophobicity. ACS Nano (2010) 1.02
Competitive displacement between two invasive whiteflies: insecticide application and host plant effects. Bull Entomol Res (2013) 1.01
Weight concerns affect motivation to remain abstinent from smoking postpartum. Ann Behav Med (2006) 1.01
Interaction of developmental transcription factor HOXC11 with steroid receptor coactivator SRC-1 mediates resistance to endocrine therapy in breast cancer [corrected]. Cancer Res (2010) 1.00
Tamoxifen-induced ER-alpha-SRC-3 interaction in HER2 positive human breast cancer; a possible mechanism for ER isoform specific recurrence. Endocr Relat Cancer (2006) 1.00