Published in J Neurosci on November 09, 2011
CaMKII regulation in information processing and storage. Trends Neurosci (2012) 1.96
CaMKII binding to GluN2B is critical during memory consolidation. EMBO J (2012) 1.62
CaMKII: claiming center stage in postsynaptic function and organization. Neuron (2014) 1.39
The CaMKII/NMDAR complex as a molecular memory. Mol Brain (2013) 1.22
DISC1 genetics, biology and psychiatric illness. Front Biol (Beijing) (2013) 1.00
Translational Concepts of mGluR5 in Synaptic Diseases of the Brain. Front Pharmacol (2012) 0.86
Modulation of behavior by scaffolding proteins of the post-synaptic density. Neurobiol Learn Mem (2013) 0.86
A Disc1 mutation differentially affects neurites and spines in hippocampal and cortical neurons. Mol Cell Neurosci (2013) 0.83
The glutamatergic aspects of schizophrenia molecular pathophysiology: role of the postsynaptic density, and implications for treatment. Curr Neuropharmacol (2014) 0.82
Fmr1 deficiency promotes age-dependent alterations in the cortical synaptic proteome. Proc Natl Acad Sci U S A (2015) 0.81
Splice variants of the CaV1.3 L-type calcium channel regulate dendritic spine morphology. Sci Rep (2016) 0.78
Regulation of Postsynaptic Stability by the L-type Calcium Channel CaV1.3 and its Interaction with PDZ Proteins. Curr Mol Pharmacol (2015) 0.77
Disrupted in schizophrenia 1 and synaptic function in the mammalian central nervous system. Eur J Neurosci (2014) 0.76
Analysis of Gene Expression Profiles in the Human Brain Stem, Cerebellum and Cerebral Cortex. PLoS One (2016) 0.76
Genetic variant analysis of the putative regulatory regions of the LRRC7 gene in bipolar disorder. Psychiatr Genet (2016) 0.75
Densin-180 Controls the Trafficking and Signaling of L-Type Voltage-Gated Cav1.2 Ca(2+) Channels at Excitatory Synapses. J Neurosci (2017) 0.75
Heterozygous deletion of the LRFN2 gene is associated with working memory deficits. Eur J Hum Genet (2015) 0.75
Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron (2000) 22.02
The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry (2003) 21.70
Functional impact of global rare copy number variation in autism spectrum disorders. Nature (2010) 14.66
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders. Nat Genet (2006) 11.14
Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet (2000) 7.16
Behavioural phenotyping assays for mouse models of autism. Nat Rev Neurosci (2010) 5.27
Dysfunction in the neural circuitry of emotion regulation--a possible prelude to violence. Science (2000) 4.86
NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CaMKII. Neuron (2005) 4.35
Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes. Nat Neurosci (2009) 4.32
Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation. N Engl J Med (2009) 3.88
A synaptic trek to autism. Curr Opin Neurobiol (2009) 3.53
Signal-processing machines at the postsynaptic density. Science (2000) 3.47
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nat Neurosci (2010) 2.90
Spine architecture and synaptic plasticity. Trends Neurosci (2005) 2.79
Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease. Neuron (2010) 2.67
Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase. Proc Natl Acad Sci U S A (1983) 2.66
Autophosphorylation-dependent targeting of calcium/ calmodulin-dependent protein kinase II by the NR2B subunit of the N-methyl- D-aspartate receptor. J Biol Chem (1998) 2.61
Modeling madness in mice: one piece at a time. Neuron (2006) 2.60
Assessing nest building in mice. Nat Protoc (2006) 2.56
Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders. Mol Brain (2008) 2.55
Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia. Mol Psychiatry (2007) 2.53
Huntington's disease: from pathology and genetics to potential therapies. Biochem J (2008) 2.41
3q29 microdeletion syndrome: clinical and molecular characterization of a new syndrome. Am J Hum Genet (2005) 2.38
A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition. Proc Natl Acad Sci U S A (2008) 2.37
Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the extracellular signal-regulated kinases (ERK) activity in cultured rat hippocampal neurons. J Physiol (2006) 2.27
Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell (1998) 2.21
Abnormal fear response and aggressive behavior in mutant mice deficient for alpha-calcium-calmodulin kinase II. Science (1994) 2.20
Schizophrenia-relevant behavioral testing in rodent models: a uniquely human disorder? Biol Psychiatry (2006) 2.11
Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A (1999) 2.08
The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases. Proc Natl Acad Sci U S A (2007) 1.99
Identification of a phosphorylation site for calcium/calmodulindependent protein kinase II in the NR2B subunit of the N-methyl-D-aspartate receptor. J Biol Chem (1996) 1.91
Understanding the role of DISC1 in psychiatric disease and during normal development. J Neurosci (2009) 1.89
How prevalent are anxiety disorders in schizophrenia? A meta-analysis and critical review on a significant association. Schizophr Bull (2009) 1.69
Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin. J Neurosci (2001) 1.58
Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice. Proc Natl Acad Sci U S A (2003) 1.53
Interactions between the NR2B receptor and CaMKII modulate synaptic plasticity and spatial learning. J Neurosci (2007) 1.51
An image analysis algorithm for dendritic spines. Neural Comput (2002) 1.48
Comorbid psychiatric disorders associated with Asperger syndrome/high-functioning autism: a community- and clinic-based study. J Autism Dev Disord (2010) 1.47
Yeast two-hybrid screens implicate DISC1 in brain development and function. Biochem Biophys Res Commun (2003) 1.47
SynGAP regulates steady-state and activity-dependent phosphorylation of cofilin. J Neurosci (2008) 1.35
Disrupted in Schizophrenia 1 (DISC1) is a multicompartmentalized protein that predominantly localizes to mitochondria. Mol Cell Neurosci (2004) 1.35
Densin-180 interacts with delta-catenin/neural plakophilin-related armadillo repeat protein at synapses. J Biol Chem (2001) 1.25
Prepulse inhibition and genetic mouse models of schizophrenia. Behav Brain Res (2009) 1.20
Aggression and anxiety: social context and neurobiological links. Front Behav Neurosci (2010) 1.18
Postsynaptic shank antagonizes dendrite branching induced by the leucine-rich repeat protein Densin-180. J Neurosci (2005) 1.16
Association of calcium/calmodulin-dependent kinase II with developmentally regulated splice variants of the postsynaptic density protein densin-180. J Biol Chem (2000) 1.13
Reduced expression of the NMDA receptor-interacting protein SynGAP causes behavioral abnormalities that model symptoms of Schizophrenia. Neuropsychopharmacology (2009) 1.09
Characterization of densin-180, a new brain-specific synaptic protein of the O-sialoglycoprotein family. J Neurosci (1996) 1.08
Transgenic up-regulation of alpha-CaMKII in forebrain leads to increased anxiety-like behaviors and aggression. Mol Brain (2009) 1.02
Phosphorylation of proteins involved in activity-dependent forms of synaptic plasticity is altered in hippocampal slices maintained in vitro. J Neurochem (2004) 1.00
The Huntington's disease mutation impairs Huntingtin's role in the transport of NF-κB from the synapse to the nucleus. Hum Mol Genet (2010) 0.97
Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-D-aspartic acid receptor up-regulation. Int J Neuropsychopharmacol (2008) 0.97
Densin-180, a synaptic protein, links to PSD-95 through its direct interaction with MAGUIN-1. Genes Cells (2002) 0.95
Mice with genetically altered glutamate receptors as models of schizophrenia: a comprehensive review. Neurosci Biobehav Rev (2009) 0.94
Advancing a functional genomics for schizophrenia: psychopathological and cognitive phenotypes in mutants with gene disruption. Brain Res Bull (2009) 0.92
The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia. Mol Psychiatry (2001) 0.92
Actin-binding protein alpha-actinin-1 interacts with the metabotropic glutamate receptor type 5b and modulates the cell surface expression and function of the receptor. J Biol Chem (2007) 0.91
SIRT1 transgenic mice show phenotypes resembling calorie restriction. Aging Cell (2007) 5.30
Increase in activity during calorie restriction requires Sirt1. Science (2005) 4.90
Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci (2007) 4.06
Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring. J Neurosci (2003) 3.50
Spine architecture and synaptic plasticity. Trends Neurosci (2005) 2.79
SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor. J Neurosci (2002) 2.46
Activation of the maternal immune system induces endocrine changes in the placenta via IL-6. Brain Behav Immun (2010) 2.29
Axonal prion protein is required for peripheral myelin maintenance. Nat Neurosci (2010) 2.25
IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. J Cell Biol (2009) 2.16
Cytokines and CNS development. Neuron (2009) 2.15
Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal. Proc Natl Acad Sci U S A (2006) 1.92
The neuropoietic cytokine family in development, plasticity, disease and injury. Nat Rev Neurosci (2007) 1.88
Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF. J Neurosci (2002) 1.88
Binding of small molecules to an adaptive protein-protein interface. Proc Natl Acad Sci U S A (2003) 1.78
Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism. Brain Behav Immun (2012) 1.77
Intrabody gene therapy ameliorates motor, cognitive, and neuropathological symptoms in multiple mouse models of Huntington's disease. J Neurosci (2009) 1.73
Phosphatidylinositol 3-kinase regulates the induction of long-term potentiation through extracellular signal-related kinase-independent mechanisms. J Neurosci (2003) 1.70
Synapse-associated protein 102/dlgh3 couples the NMDA receptor to specific plasticity pathways and learning strategies. J Neurosci (2007) 1.68
Activation of the maternal immune system alters cerebellar development in the offspring. Brain Behav Immun (2008) 1.67
Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity. J Neurosci (2004) 1.64
Ca2+/calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciums. Proc Natl Acad Sci U S A (2006) 1.64
Maternal influenza infection is likely to alter fetal brain development indirectly: the virus is not detected in the fetus. Int J Dev Neurosci (2005) 1.62
Synapse to nucleus signaling during long-term synaptic plasticity; a role for the classical active nuclear import pathway. Neuron (2004) 1.60
Facial emotion recognition in schizophrenia: when and why does it go awry? Schizophr Res (2007) 1.58
PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2. Nat Neurosci (2012) 1.58
Prenatal viral infection leads to pyramidal cell atrophy and macrocephaly in adulthood: implications for genesis of autism and schizophrenia. Cell Mol Neurobiol (2002) 1.55
SynGAP regulates spine formation. J Neurosci (2004) 1.51
Interactions between the NR2B receptor and CaMKII modulate synaptic plasticity and spatial learning. J Neurosci (2007) 1.51
Opposing effects of PSD-93 and PSD-95 on long-term potentiation and spike timing-dependent plasticity. J Physiol (2008) 1.50
Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice. Neuron (2009) 1.49
Long-term potentiation in the hippocampal CA1 region does not require insertion and activation of GluR2-lacking AMPA receptors. J Neurophysiol (2007) 1.45
Leukemia inhibitory factor promotes neural stem cell self-renewal in the adult brain. J Neurosci (2006) 1.42
Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors. J Neurosci (2010) 1.41
Modeling an autism risk factor in mice leads to permanent immune dysregulation. Proc Natl Acad Sci U S A (2012) 1.38
Monoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment. J Biol Chem (2009) 1.37
Regulation of the neuron-specific Ras GTPase-activating protein, synGAP, by Ca2+/calmodulin-dependent protein kinase II. J Biol Chem (2004) 1.36
TRPA1 channels are regulators of astrocyte basal calcium levels and long-term potentiation via constitutive D-serine release. J Neurosci (2013) 1.36
SynGAP regulates steady-state and activity-dependent phosphorylation of cofilin. J Neurosci (2008) 1.35
Maternal infection and schizophrenia: implications for prevention. Schizophr Bull (2010) 1.32
Childhood lead poisoning associated with gold ore processing: a village-level investigation-Zamfara State, Nigeria, October-November 2010. Environ Health Perspect (2012) 1.29
Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity. J Neurosci (2008) 1.28
Molecular basis for passive immunotherapy of Alzheimer's disease. Proc Natl Acad Sci U S A (2007) 1.26
Expression of the circadian clock gene Period2 in the hippocampus: possible implications for synaptic plasticity and learned behaviour. ASN Neuro (2009) 1.26
Automated home-cage behavioural phenotyping of mice. Nat Commun (2010) 1.26
Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior. Nat Neurosci (2012) 1.25
Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity. Proc Natl Acad Sci U S A (2002) 1.24
Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease. J Neurosci (2009) 1.24
Postsynaptic induction and presynaptic expression of group 1 mGluR-dependent LTD in the hippocampal CA1 region. J Neurophysiol (2002) 1.18
The cell cycle-apoptosis connection revisited in the adult brain. J Cell Biol (2005) 1.18
Maternal immune activation causes age- and region-specific changes in brain cytokines in offspring throughout development. Brain Behav Immun (2012) 1.18
Activity-dependent transport of the transcriptional coactivator CRTC1 from synapse to nucleus. Cell (2012) 1.17
Assessment of motor balance and coordination in mice using the balance beam. J Vis Exp (2011) 1.16
Mammalian septins nomenclature. Mol Biol Cell (2002) 1.16
NMDA receptor activation dephosphorylates AMPA receptor glutamate receptor 1 subunits at threonine 840. J Neurosci (2007) 1.12
In situ assembly of enzyme inhibitors using extended tethering. Nat Biotechnol (2003) 1.11
A role for calcium-permeable AMPA receptors in synaptic plasticity and learning. PLoS One (2010) 1.11
Lymphocyte regulation of neuropeptide gene expression after neuronal injury. J Neurosci Res (2003) 1.10
TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function. J Neurosci (2012) 1.10
Placental regulation of maternal-fetal interactions and brain development. Dev Neurobiol (2012) 1.08
The RAS effector RIN1 modulates the formation of aversive memories. J Neurosci (2003) 1.08
Maternal immune activation alters nonspatial information processing in the hippocampus of the adult offspring. Brain Behav Immun (2010) 1.07
Structural modeling of protein interactions by analogy: application to PSD-95. PLoS Comput Biol (2006) 1.07
Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs. Proc Natl Acad Sci U S A (2008) 1.06
The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration. Exp Gerontol (2008) 1.04
Structural features and domain organization of huntingtin fibrils. J Biol Chem (2012) 1.04
Burden of disease and circulating serotypes of rotavirus infection in sub-Saharan Africa: systematic review and meta-analysis. Lancet Infect Dis (2009) 1.04
Palatable meal anticipation in mice. PLoS One (2010) 1.02
Leukemia inhibitory factor promotes oligodendrocyte survival after spinal cord injury. Glia (2005) 1.01
Generating single-copy nuclear gene data for a recent adaptive radiation. Mol Phylogenet Evol (2005) 1.01
Endothelin receptor B inhibition triggers apoptosis and enhances angiogenesis in melanomas. Cancer Res (2004) 1.01
Phosphorylation of proteins involved in activity-dependent forms of synaptic plasticity is altered in hippocampal slices maintained in vitro. J Neurochem (2004) 1.00
Food anticipatory activity behavior of mice across a wide range of circadian and non-circadian intervals. PLoS One (2012) 1.00
A dynamic model of interactions of Ca2+, calmodulin, and catalytic subunits of Ca2+/calmodulin-dependent protein kinase II. PLoS Comput Biol (2010) 1.00
Activity-dependent anchoring of importin alpha at the synapse involves regulated binding to the cytoplasmic tail of the NR1-1a subunit of the NMDA receptor. J Neurosci (2009) 0.98
The Huntington's disease mutation impairs Huntingtin's role in the transport of NF-κB from the synapse to the nucleus. Hum Mol Genet (2010) 0.97
Influenza viruses in Nigeria, 2009-2010: results from the first 17 months of a national influenza sentinel surveillance system. J Infect Dis (2012) 0.97
Ionotropic NMDA receptor signaling is required for the induction of long-term depression in the mouse hippocampal CA1 region. J Neurosci (2014) 0.97
Potent pro-inflammatory actions of leukemia inhibitory factor in the spinal cord of the adult mouse. Exp Neurol (2004) 0.96
Therapeutic testosterone administration preserves excitatory synaptic transmission in the hippocampus during autoimmune demyelinating disease. J Neurosci (2012) 0.95
Exogenous leukemia inhibitory factor stimulates oligodendrocyte progenitor cell proliferation and enhances hippocampal remyelination. J Neurosci (2012) 0.94
Quantification of facial expressions using high-dimensional shape transformations. J Neurosci Methods (2005) 0.94
The epidemiology of human rotavirus associated with diarrhoea in Kenyan children: a review. J Trop Pediatr (2008) 0.93
Identification of potent and selective small-molecule inhibitors of caspase-3 through the use of extended tethering and structure-based drug design. J Med Chem (2002) 0.92
Single gene deletions of orexin, leptin, neuropeptide Y, and ghrelin do not appreciably alter food anticipatory activity in mice. PLoS One (2011) 0.92
'Silent' priming of translation-dependent LTP by ß-adrenergic receptors involves phosphorylation and recruitment of AMPA receptors. Learn Mem (2010) 0.92
Detailed state model of CaMKII activation and autophosphorylation. Eur Biophys J (2008) 0.90
Autism: neuropathology, alterations of the GABAergic system, and animal models. Int Rev Neurobiol (2005) 0.90
Daily timed sexual interaction induces moderate anticipatory activity in mice. PLoS One (2010) 0.89
Quantitative chimeric analysis of six specificity determinants that differentiate Escherichia coli aspartate from tyrosine aminotransferase. Protein Sci (2002) 0.88
Estriol preserves synaptic transmission in the hippocampus during autoimmune demyelinating disease. Lab Invest (2012) 0.88
The role of IκB kinase complex in the neurobiology of Huntington's disease. Neurobiol Dis (2011) 0.87
IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin. PLoS One (2009) 0.87
Two rotavirus outbreaks caused by genotype G2P[4] at large retirement communities: cohort studies. Ann Intern Med (2012) 0.87
Leukemia inhibitory factor is a key regulator of astrocytic, microglial and neuronal responses in a low-dose pilocarpine injury model. Brain Res (2006) 0.87
Short trains of theta frequency stimulation enhance CA1 pyramidal neuron excitability in the absence of synaptic potentiation. J Neurosci (2009) 0.86
Subcellular organization of camkii in rat hippocampal pyramidal neurons. J Comp Neurol (2013) 0.85
A role for synGAP in regulating neuronal apoptosis. Eur J Neurosci (2005) 0.85
Daily scheduled high fat meals moderately entrain behavioral anticipatory activity, body temperature, and hypothalamic c-Fos activation. PLoS One (2012) 0.84