Published in J Neurosci on November 09, 2011
Retracted Chronic neuroinflammation and cognitive impairment following transient global cerebral ischemia: role of fractalkine/CX3CR1 signaling. J Neuroinflammation (2014) 1.63
Microglial responses after ischemic stroke and intracerebral hemorrhage. Clin Dev Immunol (2013) 1.43
Microglia and ischemic stroke: a double-edged sword. Int J Physiol Pathophysiol Pharmacol (2013) 1.33
Microglia, seen from the CX3CR1 angle. Front Cell Neurosci (2013) 1.30
Microglia activation as a biomarker for traumatic brain injury. Front Neurol (2013) 1.23
Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage. Open Biol (2013) 1.21
Primary phagocytosis of neurons by inflamed microglia: potential roles in neurodegeneration. Front Pharmacol (2012) 1.20
The role of microglia and myeloid immune cells in acute cerebral ischemia. Front Cell Neurosci (2015) 1.12
Modulating neurotoxicity through CX3CL1/CX3CR1 signaling. Front Cell Neurosci (2014) 1.12
The brain's best friend: microglial neurotoxicity revisited. Front Cell Neurosci (2013) 1.09
The ischemic environment drives microglia and macrophage function. Front Neurol (2015) 1.09
Targeting mannose-binding lectin confers long-lasting protection with a surprisingly wide therapeutic window in cerebral ischemia. Circulation (2012) 1.03
Fractalkine (CX3CL1) enhances hippocampal N-methyl-D-aspartate receptor (NMDAR) function via D-serine and adenosine receptor type A2 (A2AR) activity. J Neuroinflammation (2013) 1.03
Rational modulation of the innate immune system for neuroprotection in ischemic stroke. Front Neurosci (2015) 1.02
Post-insult valproic acid-regulated microRNAs: potential targets for cerebral ischemia. Am J Transl Res (2012) 0.99
CCL2 upregulation triggers hypoxic preconditioning-induced protection from stroke. J Neuroinflammation (2012) 0.99
Trasmembrane chemokines CX3CL1 and CXCL16 drive interplay between neurons, microglia and astrocytes to counteract pMCAO and excitotoxic neuronal death. Front Cell Neurosci (2014) 0.91
Hypoxia-inducible factor 1 contributes to N-acetylcysteine's protection in stroke. Free Radic Biol Med (2013) 0.88
CX3CR1 signaling on monocytes is dispensable after intracerebral hemorrhage. PLoS One (2014) 0.86
Higher plasma fractalkine is associated with better 6-month outcome from ischemic stroke. Stroke (2012) 0.84
Help-me signaling: Non-cell autonomous mechanisms of neuroprotection and neurorecovery. Prog Neurobiol (2016) 0.83
Time-dependent effects of CX3CR1 in a mouse model of mild traumatic brain injury. J Neuroinflammation (2015) 0.83
Treatment with AMD3100 attenuates the microglial response and improves outcome after experimental stroke. J Neuroinflammation (2015) 0.82
Adenosine A1 receptors contribute to immune regulation after neonatal hypoxic ischemic brain injury. Purinergic Signal (2015) 0.82
CX3CL1 is up-regulated in the rat hippocampus during memory-associated synaptic plasticity. Front Cell Neurosci (2014) 0.81
Modeling early-onset post-ischemic seizures in aging mice. Exp Neurol (2015) 0.81
HIV-1 Tat disrupts CX3CL1-CX3CR1 axis in microglia via the NF-κBYY1 pathway. Curr HIV Res (2014) 0.80
CX3CL1/CX3CR1-mediated microglia activation plays a detrimental role in ischemic mice brain via p38MAPK/PKC pathway. J Cereb Blood Flow Metab (2015) 0.79
CX3CL1, a chemokine finely tuned to adhesion: critical roles of the stalk glycosylation and the membrane domain. Biol Open (2014) 0.79
Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice. Biomed Res Int (2015) 0.78
CX3CR1 deficiency delays acute skeletal muscle injury repair by impairing macrophage functions. FASEB J (2015) 0.78
Method parameters' impact on mortality and variability in mouse stroke experiments: a meta-analysis. Sci Rep (2016) 0.77
Neuroinflammation and neuroimmune dysregulation after acute hypoxic-ischemic injury of developing brain. Front Pediatr (2015) 0.77
The temporal dynamics of plasma fractalkine levels in ischemic stroke: association with clinical severity and outcome. J Neuroinflammation (2014) 0.77
Transcriptional analysis of apoptotic cerebellar granule neurons following rescue by gastric inhibitory polypeptide. Int J Mol Sci (2014) 0.77
Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions in human astrocytes. J Neuroinflammation (2016) 0.76
Fractalkine Receptor Deficiency Is Associated with Early Protection but Late Worsening of Outcome following Brain Trauma in Mice. J Neurotrauma (2015) 0.76
Inhibition of autophagy prevents irradiation-induced neural stem and progenitor cell death in the juvenile mouse brain. Cell Death Dis (2017) 0.75
CX3C chemokine receptor 1 deficiency modulates microglia morphology but does not affect lesion size and short-term deficits after experimental stroke. BMC Neurosci (2017) 0.75
Analysis of the Role of CX3CL1 (Fractalkine) and Its Receptor CX3CR1 in Traumatic Brain and Spinal Cord Injury: Insight into Recent Advances in Actions of Neurochemokine Agents. Mol Neurobiol (2016) 0.75
Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice. Nat Commun (2017) 0.75
Update on Inflammatory Biomarkers and Treatments in Ischemic Stroke. Int J Mol Sci (2016) 0.75
Fractalkine: multiple strategies to counteract glutamate receptors activation leading to neuroprotection. Neural Regen Res (2015) 0.75
The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia. J Neuroinflammation (2017) 0.75
The chemokine fractalkine (CX3CL1) attenuates H2O2-induced demyelination in cerebellar slices. J Neuroinflammation (2017) 0.75
Alterations in the Interplay between Neurons, Astrocytes and Microglia in the Rat Dentate Gyrus in Experimental Models of Neurodegeneration. Front Aging Neurosci (2017) 0.75
Anti-Inflammatory Targets for the Treatment of Reperfusion Injury in Stroke. Front Neurol (2017) 0.75
Derivatives of erythropoietin that are tissue protective but not erythropoietic. Science (2004) 4.09
Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine. Nat Neurosci (2005) 2.34
Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin. Proc Natl Acad Sci U S A (2008) 2.21
Signalling from adenosine receptors to mitogen-activated protein kinases. Cell Signal (2003) 2.19
Activation and inhibition of human muscular and neuronal nicotinic acetylcholine receptors by succinylcholine. Anesthesiology (2006) 2.19
Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury. Proc Natl Acad Sci U S A (2004) 2.06
Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis. Brain Res (2002) 2.04
Human umbilical cord blood mesenchymal stem cells protect mice brain after trauma. Crit Care Med (2011) 1.95
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine. Nature (2002) 1.91
Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo. Proc Natl Acad Sci U S A (2003) 1.88
Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice. J Neuroinflammation (2011) 1.84
A ketogenic diet suppresses seizures in mice through adenosine A₁ receptors. J Clin Invest (2011) 1.79
Adenosine receptors as drug targets--what are the challenges? Nat Rev Drug Discov (2013) 1.74
Functional role of inflammatory cytokines and antiinflammatory molecules in seizures and epileptogenesis. Epilepsia (2002) 1.66
C1-inhibitor attenuates neurobehavioral deficits and reduces contusion volume after controlled cortical impact brain injury in mice. Crit Care Med (2009) 1.64
Fractalkine/CX3CL1 modulates GABAA currents in human temporal lobe epilepsy. Epilepsia (2013) 1.50
Mannose-binding lectin is expressed after clinical and experimental traumatic brain injury and its deletion is protective. Crit Care Med (2014) 1.45
Sleep and its homeostatic regulation in mice lacking the adenosine A1 receptor. J Sleep Res (2003) 1.44
Functional properties of cells obtained from human cord blood CD34+ stem cells and mouse cardiac myocytes in coculture. Am J Physiol Heart Circ Physiol (2008) 1.42
Tumor necrosis factor-alpha inhibits seizures in mice via p75 receptors. Ann Neurol (2005) 1.41
Adenosine A1 receptors are crucial in keeping an epileptic focus localized. Exp Neurol (2006) 1.40
Glia activation and cytokine increase in rat hippocampus by kainic acid-induced status epilepticus during postnatal development. Neurobiol Dis (2003) 1.39
Expression of functional neurotransmitter receptors in Xenopus oocytes after injection of human brain membranes. Proc Natl Acad Sci U S A (2002) 1.36
Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens. J Neurosci (2011) 1.35
Recombinant C1 inhibitor in brain ischemic injury. Ann Neurol (2009) 1.33
Neurosphere-derived cells exert a neuroprotective action by changing the ischemic microenvironment. PLoS One (2007) 1.33
Identification of proteins undergoing glutathionylation in oxidatively stressed hepatocytes and hepatoma cells. Proteomics (2003) 1.31
Cytokines and innate inflammation in the pathogenesis of human traumatic brain injury. Prog Neurobiol (2011) 1.31
Chemokine CX3CL1 protects rat hippocampal neurons against glutamate-mediated excitotoxicity. J Neuroimmunol (2005) 1.30
Activity of adenosine receptors type 1 Is required for CX3CL1-mediated neuroprotection and neuromodulation in hippocampal neurons. J Immunol (2008) 1.29
CXCL12-induced glioblastoma cell migration requires intermediate conductance Ca2+-activated K+ channel activity. Am J Physiol Cell Physiol (2010) 1.27
Adenosine dysfunction in astrogliosis: cause for seizure generation? Neuron Glia Biol (2007) 1.23
Modulation of hippocampal glutamatergic transmission by ATP is dependent on adenosine a(1) receptors. J Pharmacol Exp Ther (2002) 1.22
Peripheral treatment with enoxaparin, a low molecular weight heparin, reduces plaques and beta-amyloid accumulation in a mouse model of Alzheimer's disease. J Neurosci (2004) 1.21
Early administration of low-dose aspirin for the prevention of severe and mild preeclampsia: a systematic review and meta-analysis. Am J Perinatol (2012) 1.18
A1 adenosine receptors mediate hypoxia-induced ventriculomegaly. Proc Natl Acad Sci U S A (2003) 1.18
Microtransplantation of neurotransmitter receptors from cells to Xenopus oocyte membranes: new procedure for ion channel studies. Methods Mol Biol (2006) 1.18
CX3CR1 deficiency induces an early protective inflammatory environment in ischemic mice. Glia (2013) 1.17
Effect of modulating cardiac A1 adenosine receptor expression on protection with ischemic preconditioning. Am J Physiol Heart Circ Physiol (2005) 1.17
The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38. Exp Cell Res (2003) 1.17
The human adult subtype ACh receptor channel has high Ca2+ permeability and predisposes to endplate Ca2+ overloading. J Physiol (2006) 1.16
Increased nociceptive response in mice lacking the adenosine A1 receptor. Pain (2005) 1.16
Inflammatory response and glia activation in developing rat hippocampus after status epilepticus. Epilepsia (2005) 1.16
Early administration of low-dose aspirin for the prevention of preterm and term preeclampsia: a systematic review and meta-analysis. Fetal Diagn Ther (2012) 1.16
Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production. J Neurochem (2011) 1.16
Neuroprotection with the CXCL8 inhibitor repertaxin in transient brain ischemia. Cytokine (2005) 1.15
Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A1 receptors and promotes non-rapid eye movement sleep. Proc Natl Acad Sci U S A (2008) 1.15
Erythropoietin protects primary hippocampal neurons increasing the expression of brain-derived neurotrophic factor. J Neurochem (2005) 1.13
MRI evaluation and functional assessment of brain injury after hypoxic ischemia in neonatal mice. Stroke (2002) 1.13
Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function. FASEB J (2010) 1.12
Aggravated brain damage after hypoxic ischemia in immature adenosine A2A knockout mice. Stroke (2003) 1.12
Adenosine and ATP receptors in the brain. Curr Top Med Chem (2011) 1.10
Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death. Neuropsychopharmacology (2010) 1.10
Modulation of glial cell functions by adenosine receptors. Physiol Behav (2007) 1.09
Mice lacking the adenosine A1 receptor are anxious and aggressive, but are normal learners with reduced muscle strength and survival rate. Eur J Neurosci (2002) 1.08
Adenosine A(1) receptors regulate bone resorption in mice: adenosine A(1) receptor blockade or deletion increases bone density and prevents ovariectomy-induced bone loss in adenosine A(1) receptor-knockout mice. Arthritis Rheum (2010) 1.08
Physiological roles of A1 and A2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine. Am J Physiol Heart Circ Physiol (2009) 1.08
Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neurons. J Neurosci (2005) 1.07
Effects of cyclothiazide on GluR1/AMPA receptors. Proc Natl Acad Sci U S A (2006) 1.06
Golf putt outcomes are predicted by sensorimotor cerebral EEG rhythms. J Physiol (2007) 1.05
One-pot synthesis and characterization of size-controlled bimagnetic FePt-iron oxide heterodimer nanocrystals. J Am Chem Soc (2008) 1.05
Chemokine fractalkine/CX3CL1 negatively modulates active glutamatergic synapses in rat hippocampal neurons. J Neurosci (2006) 1.04
1,3,7-trimethylxanthine (caffeine) may exacerbate acute inflammatory liver injury by weakening the physiological immunosuppressive mechanism. J Immunol (2007) 1.04
"Neural efficiency" of experts' brain during judgment of actions: a high-resolution EEG study in elite and amateur karate athletes. Behav Brain Res (2009) 1.03
Bovine serum albumin-based magnetic nanocarrier for MRI diagnosis and hyperthermic therapy: a potential theranostic approach against cancer. Small (2010) 1.03
Amyloid beta(1-42) peptide alters the gating of human and mouse alpha-bungarotoxin-sensitive nicotinic receptors. J Physiol (2003) 1.03
Targeting mannose-binding lectin confers long-lasting protection with a surprisingly wide therapeutic window in cerebral ischemia. Circulation (2012) 1.03
C1-inhibitor protects against brain ischemia-reperfusion injury via inhibition of cell recruitment and inflammation. Neurobiol Dis (2005) 1.03
Fractalkine (CX3CL1) enhances hippocampal N-methyl-D-aspartate receptor (NMDAR) function via D-serine and adenosine receptor type A2 (A2AR) activity. J Neuroinflammation (2013) 1.03
Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke. Proc Natl Acad Sci U S A (2012) 1.02
Abnormal GABAA receptors from the human epileptic hippocampal subiculum microtransplanted to Xenopus oocytes. Proc Natl Acad Sci U S A (2005) 1.02
Adenosine A1 receptors regulate lipolysis and lipogenesis in mouse adipose tissue-interactions with insulin. Eur J Pharmacol (2008) 1.02
Ligand-independent CXCR2 dimerization. J Biol Chem (2003) 1.02
A1 adenosine receptors play an essential role in protecting the embryo against hypoxia. Proc Natl Acad Sci U S A (2007) 1.02
CX(3)CR1 deficiency alters hippocampal-dependent plasticity phenomena blunting the effects of enriched environment. Front Cell Neurosci (2011) 1.02
LTP impairment by fractalkine/CX3CL1 in mouse hippocampus is mediated through the activity of adenosine receptor type 3 (A3R). J Neuroimmunol (2009) 1.01
Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells. J Allergy Clin Immunol (2008) 1.01
Evidence for functional adenosine A3 receptors in microglia cells. J Neurochem (2003) 1.01
The single-channel properties of human acetylcholine alpha 7 receptors are altered by fusing alpha 7 to the green fluorescent protein. Proc Natl Acad Sci U S A (2002) 1.01
Influence of the adenosine A1 receptor on blood pressure regulation and renin release. Am J Physiol Regul Integr Comp Physiol (2005) 1.01
Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis. Hum Mol Genet (2009) 1.01
Directionality of EEG synchronization in Alzheimer's disease subjects. Neurobiol Aging (2007) 1.00
Fractional Ca(2+) current through human neuronal alpha7 nicotinic acetylcholine receptors. Cell Calcium (2003) 0.99