Published in Biomark Med on December 01, 2011
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PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6. Pharmacogenet Genomics (2012) 0.92
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BioBin: a bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge. BMC Med Genomics (2013) 0.90
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Pathway analysis of genome-wide data improves warfarin dose prediction. BMC Genomics (2013) 0.87
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A pharmacogenetics service experience for pharmacy students, residents, and fellows. Am J Pharm Educ (2013) 0.86
Pharmacogenetics in American Indian populations: analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes. Pharmacogenet Genomics (2013) 0.86
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Bioinformatic Resources of microRNA Sequences, Gene Targets, and Genetic Variation. Front Genet (2012) 0.84
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Multilocus genotypes of relevance for drug metabolizing enzymes and therapy with thiopurines in patients with acute lymphoblastic leukemia. Front Genet (2013) 0.82
Drug2Gene: an exhaustive resource to explore effectively the drug-target relation network. BMC Bioinformatics (2014) 0.82
Effects of protein interaction data integration, representation and reliability on the use of network properties for drug target prediction. BMC Bioinformatics (2012) 0.82
Using BioBin to explore rare variant population stratification. Pac Symp Biocomput (2013) 0.81
SASD: the Synthetic Alternative Splicing Database for identifying novel isoform from proteomics. BMC Bioinformatics (2013) 0.81
Variation in genes controlling warfarin disposition and response in American Indian and Alaska Native people: CYP2C9, VKORC1, CYP4F2, CYP4F11, GGCX. Pharmacogenet Genomics (2015) 0.81
Cataloging the biomedical world of pain through semi-automated curation of molecular interactions. Database (Oxford) (2013) 0.80
Non-coding polymorphisms in nucleotide binding domain 1 in ABCC1 gene associate with transcript level and survival of patients with breast cancer. PLoS One (2014) 0.79
Molecular biomarkers for grass pollen immunotherapy. World J Methodol (2014) 0.79
Toward semantic modeling of pharmacogenomic knowledge for clinical and translational decision support. AMIA Jt Summits Transl Sci Proc (2013) 0.79
Pathway-based Biomarkers for Breast Cancer in Proteomics. Cancer Inform (2015) 0.78
KNOWLEDGE DRIVEN BINNING AND PHEWAS ANALYSIS IN MARSHFIELD PERSONALIZED MEDICINE RESEARCH PROJECT USING BIOBIN. Pac Symp Biocomput (2016) 0.77
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Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202. Pharmacogenet Genomics (2015) 0.76
Pharmacogenomics, Theranostics and Personalized Medicine - the complexities of clinical trials: challenges in the developing world. Appl Transl Genom (2013) 0.75
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Evolutionary Diagnosis of non-synonymous variants involved in differential drug response. BMC Med Genomics (2015) 0.75
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NiaoDuQing granules relieve chronic kidney disease symptoms by decreasing renal fibrosis and anemia. Oncotarget (2017) 0.75
DrugBank: a comprehensive resource for in silico drug discovery and exploration. Nucleic Acids Res (2006) 15.19
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DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res (2010) 13.68
CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin Pharmacol Ther (2011) 10.95
The BioPAX community standard for pathway data sharing. Nat Biotechnol (2010) 9.19
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Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing. Clin Pharmacol Ther (2011) 4.42
Pharmacogenetics: from bench to byte--an update of guidelines. Clin Pharmacol Ther (2011) 3.36
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Recent progress in automatically extracting information from the pharmacogenomic literature. Pharmacogenomics (2010) 1.88
Integration and publication of heterogeneous text-mined relationships on the Semantic Web. J Biomed Semantics (2011) 1.29
PharmGKB summary: methotrexate pathway. Pharmacogenet Genomics (2011) 1.27
Translational aspects of genetic factors in the prediction of drug response variability: a case study of warfarin pharmacogenomics in a multi-ethnic cohort from Asia. Pharmacogenomics J (2011) 1.08
PharmGKB summary: very important pharmacogene information for PTGS2. Pharmacogenet Genomics (2011) 1.03
Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell (2012) 12.32
Clinical assessment incorporating a personal genome. Lancet (2010) 10.18
The BioPAX community standard for pathway data sharing. Nat Biotechnol (2010) 9.19
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The incidentalome: a threat to genomic medicine. JAMA (2006) 7.24
Genetics. Genomic research and human subject privacy. Science (2004) 6.56
PharmGKB: the Pharmacogenetics Knowledge Base. Nucleic Acids Res (2002) 6.40
A Bayesian framework for combining heterogeneous data sources for gene function prediction (in Saccharomyces cerevisiae). Proc Natl Acad Sci U S A (2003) 6.19
Knowledge acquisition, consistency checking and concurrency control for Gene Ontology (GO). Bioinformatics (2003) 3.97
SAFA: semi-automated footprinting analysis software for high-throughput quantification of nucleic acid footprinting experiments. RNA (2005) 3.95
Associating genes with gene ontology codes using a maximum entropy analysis of biomedical literature. Genome Res (2002) 3.77
Nonparametric methods for identifying differentially expressed genes in microarray data. Bioinformatics (2002) 3.65
Health-information altruists--a potentially critical resource. N Engl J Med (2005) 3.61
The RNA Ontology Consortium: an open invitation to the RNA community. RNA (2006) 3.60
Creating an online dictionary of abbreviations from MEDLINE. J Am Med Inform Assoc (2002) 3.32
Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study. Lancet (2013) 3.21
Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. PLoS Genet (2011) 3.20
Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups. Blood (2010) 2.93
Data-driven prediction of drug effects and interactions. Sci Transl Med (2012) 2.93
Challenges in the clinical application of whole-genome sequencing. Lancet (2010) 2.92
Eukaryotic regulatory element conservation analysis and identification using comparative genomics. Genome Res (2004) 2.84
PharmGKB: a logical home for knowledge relating genotype to drug response phenotype. Nat Genet (2007) 2.65
Coarse-grained modeling of large RNA molecules with knowledge-based potentials and structural filters. RNA (2009) 2.63
A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports. J Am Med Inform Assoc (2011) 2.53
Clinical implementation of pharmacogenomics: overcoming genetic exceptionalism. Lancet Oncol (2010) 2.52
The pharmacogenetics and pharmacogenomics knowledge base: accentuating the knowledge. Nucleic Acids Res (2007) 2.45
The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation. Clin Pharmacol Ther (2013) 2.39
Bioinformatics challenges for personalized medicine. Bioinformatics (2011) 2.28
Time to organize the bioinformatics resourceome. PLoS Comput Biol (2005) 2.25
MScanner: a classifier for retrieving Medline citations. BMC Bioinformatics (2008) 2.24
Using binning to maintain confidentiality of medical data. Proc AMIA Symp (2002) 2.23
Web-scale pharmacovigilance: listening to signals from the crowd. J Am Med Inform Assoc (2013) 2.19
Using text to build semantic networks for pharmacogenomics. J Biomed Inform (2010) 2.19
Pharmspresso: a text mining tool for extraction of pharmacogenomic concepts and relationships from full text. BMC Bioinformatics (2009) 2.15
PharmGKB: understanding the effects of individual genetic variants. Drug Metab Rev (2008) 2.09
GAPSCORE: finding gene and protein names one word at a time. Bioinformatics (2004) 2.05
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Computational analysis of Plasmodium falciparum metabolism: organizing genomic information to facilitate drug discovery. Genome Res (2004) 1.92
Pharmacogenomics and bioinformatics: PharmGKB. Pharmacogenomics (2010) 1.91
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Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process. Curr Drug Metab (2014) 1.88
Automating data acquisition into ontologies from pharmacogenetics relational data sources using declarative object definitions and XML. Pac Symp Biocomput (2002) 1.81
PharmGKB: the Pharmacogenomics Knowledge Base. Methods Mol Biol (2013) 1.81
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High-throughput single-nucleotide structural mapping by capillary automated footprinting analysis. Nucleic Acids Res (2008) 1.78
Using text analysis to identify functionally coherent gene groups. Genome Res (2002) 1.71
The FEATURE framework for protein function annotation: modeling new functions, improving performance, and extending to novel applications. BMC Genomics (2008) 1.64
Challenges for biomedical informatics and pharmacogenomics. Annu Rev Pharmacol Toxicol (2002) 1.61
Finding haplotype tagging SNPs by use of principal components analysis. Am J Hum Genet (2004) 1.61
Preemptive clinical pharmacogenetics implementation: current programs in five US medical centers. Annu Rev Pharmacol Toxicol (2014) 1.58
MutDB: annotating human variation with functionally relevant data. Bioinformatics (2003) 1.54
Structural inference of native and partially folded RNA by high-throughput contact mapping. Proc Natl Acad Sci U S A (2008) 1.54
Doxorubicin pathways: pharmacodynamics and adverse effects. Pharmacogenet Genomics (2011) 1.53
Discovery and explanation of drug-drug interactions via text mining. Pac Symp Biocomput (2012) 1.53
Training the next generation of informaticians: the impact of "BISTI" and bioinformatics--a report from the American College of Medical Informatics. J Am Med Inform Assoc (2004) 1.53
The computational analysis of scientific literature to define and recognize gene expression clusters. Nucleic Acids Res (2003) 1.44
Mutation and polymorphism spectrum in osteogenesis imperfecta type II: implications for genotype-phenotype relationships. Hum Mol Genet (2008) 1.42
The functional importance of disease-associated mutation. BMC Bioinformatics (2002) 1.41
Independent component analysis: mining microarray data for fundamental human gene expression modules. J Biomed Inform (2010) 1.39
Local kinetic measures of macromolecular structure reveal partitioning among multiple parallel pathways from the earliest steps in the folding of a large RNA molecule. J Mol Biol (2006) 1.38
Metformin pathways: pharmacokinetics and pharmacodynamics. Pharmacogenet Genomics (2012) 1.38
A statistical approach to scanning the biomedical literature for pharmacogenetics knowledge. J Am Med Inform Assoc (2004) 1.37
WebFEATURE: An interactive web tool for identifying and visualizing functional sites on macromolecular structures. Nucleic Acids Res (2003) 1.35
A literature-based method for assessing the functional coherence of a gene group. Bioinformatics (2003) 1.33
A call for the creation of personalized medicine databases. Nat Rev Drug Discov (2006) 1.30
Extracting and characterizing gene-drug relationships from the literature. Pharmacogenetics (2004) 1.30
Using ODIN for a PharmGKB revalidation experiment. Database (Oxford) (2012) 1.29
Integration and publication of heterogeneous text-mined relationships on the Semantic Web. J Biomed Semantics (2011) 1.29
Biomedical term mapping databases. Nucleic Acids Res (2005) 1.29
Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein). Pharmacogenet Genomics (2011) 1.29
Informatics confronts drug-drug interactions. Trends Pharmacol Sci (2013) 1.28