Patrick J Stover

Author PubWeight™ 48.47‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses. J Biol Chem 2002 2.20
2 Folate-mediated one-carbon metabolism. Vitam Horm 2008 1.81
3 Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice. J Biol Chem 2008 1.73
4 Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway. J Biol Chem 2007 1.65
5 Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice. Am J Clin Nutr 2011 1.53
6 SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis. PLoS One 2009 1.51
7 Folate-mediated one-carbon metabolism and neural tube defects: balancing genome synthesis and gene expression. Birth Defects Res C Embryo Today 2007 1.42
8 Small ubiquitin-like modifier-1 (SUMO-1) modification of thymidylate synthase and dihydrofolate reductase. Clin Chem Lab Med 2007 1.38
9 Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria. Proc Natl Acad Sci U S A 2011 1.30
10 Insights into metabolic mechanisms underlying folate-responsive neural tube defects: a minireview. Birth Defects Res A Clin Mol Teratol 2009 1.29
11 Regulation of de novo purine biosynthesis by methenyltetrahydrofolate synthetase in neuroblastoma. J Biol Chem 2005 1.28
12 Dietary folate, but not choline, modifies neural tube defect risk in Shmt1 knockout mice. Am J Clin Nutr 2011 1.19
13 Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men. J Nutr 2005 1.17
14 Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk. Cancer Res 2011 1.16
15 Serine hydroxymethyltransferase anchors de novo thymidylate synthesis pathway to nuclear lamina for DNA synthesis. J Biol Chem 2012 1.16
16 Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. J Biol Chem 2008 1.14
17 Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase. J Biol Chem 2006 1.13
18 A ferritin-responsive internal ribosome entry site regulates folate metabolism. J Biol Chem 2007 1.09
19 Methenyltetrahydrofolate synthetase regulates folate turnover and accumulation. J Biol Chem 2003 1.04
20 Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells. Arch Biochem Biophys 2007 1.01
21 Competition between sumoylation and ubiquitination of serine hydroxymethyltransferase 1 determines its nuclear localization and its accumulation in the nucleus. J Biol Chem 2011 1.01
22 A UV-responsive internal ribosome entry site enhances serine hydroxymethyltransferase 1 expression for DNA damage repair. J Biol Chem 2009 1.01
23 Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA. J Biol Chem 2011 0.99
24 Mechanism of the internal ribosome entry site-mediated translation of serine hydroxymethyltransferase 1. J Biol Chem 2009 0.99
25 Mimosine attenuates serine hydroxymethyltransferase transcription by chelating zinc. Implications for inhibition of DNA replication. J Biol Chem 2004 0.98
26 High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5. BMC Genet 2010 0.95
27 Modeling cellular compartmentation in one-carbon metabolism. Wiley Interdiscip Rev Syst Biol Med 2013 0.94
28 Convergence of genetic, nutritional and inflammatory factors in gastrointestinal cancers. Nutr Rev 2007 0.89
29 Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration. J Nutr 2012 0.89
30 Cloning, expression, and purification of 5,10-methenyltetrahydrofolate synthetase from Mus musculus. Protein Expr Purif 2004 0.89
31 5,10-Methenyltetrahydrofolate synthetase activity is increased in tumors and modifies the efficacy of antipurine LY309887. Arch Biochem Biophys 2008 0.89
32 Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice. Am J Clin Nutr 2012 0.88
33 Pyridoxal phosphate inhibits dynamic subunit interchange among serine hydroxymethyltransferase tetramers. J Biol Chem 2003 0.87
34 Mthfs is an Essential Gene in Mice and a Component of the Purinosome. Front Genet 2011 0.87
35 Mthfd1 is a modifier of chemically induced intestinal carcinogenesis. Carcinogenesis 2010 0.86
36 Supplemental dietary folic acid has no effect on chromosome damage in erythrocyte progenitor cells of mice. J Nutr 2012 0.82
37 Folate network genetic variation, plasma homocysteine, and global genomic methylation content: a genetic association study. BMC Med Genet 2011 0.82
38 Folate network genetic variation predicts cardiovascular disease risk in non-Hispanic white males. J Nutr 2012 0.80
39 Polymorphisms in serine hydroxymethyltransferase 1 and methylenetetrahydrofolate reductase interact to increase cardiovascular disease risk in humans. J Nutr 2010 0.80
40 Disruption of shmt1 impairs hippocampal neurogenesis and mnemonic function in mice. J Nutr 2013 0.79
41 Methenyltetrahydrofolate synthetase is a high-affinity catecholamine-binding protein. Arch Biochem Biophys 2006 0.78
42 Inhibition of 5,10-methenyltetrahydrofolate synthetase. Arch Biochem Biophys 2007 0.78
43 Folate supplementation in people with sickle cell disease. Cochrane Database Syst Rev 2016 0.77
44 Securing the future of nutritional sciences through integrative graduate education. J Nutr 2002 0.76
45 Nutritional regulation of epigenetic changes. Adv Nutr 2012 0.75
46 Azoxymethane-induced colon carcinogenesis in mice occurs independently of de novo thymidylate synthesis capacity. J Nutr 2014 0.75