1
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2
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Folate-mediated one-carbon metabolism.
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Vitam Horm
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2008
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1.81
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3
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Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice.
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J Biol Chem
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2008
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1.73
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4
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Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway.
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J Biol Chem
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2007
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1.65
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5
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Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice.
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Am J Clin Nutr
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2011
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1.53
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6
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SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis.
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2009
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1.51
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7
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Folate-mediated one-carbon metabolism and neural tube defects: balancing genome synthesis and gene expression.
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2007
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8
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Small ubiquitin-like modifier-1 (SUMO-1) modification of thymidylate synthase and dihydrofolate reductase.
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Clin Chem Lab Med
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2007
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1.38
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9
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Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria.
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Proc Natl Acad Sci U S A
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2011
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1.30
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10
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Insights into metabolic mechanisms underlying folate-responsive neural tube defects: a minireview.
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2009
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1.29
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11
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Regulation of de novo purine biosynthesis by methenyltetrahydrofolate synthetase in neuroblastoma.
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J Biol Chem
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2005
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1.28
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12
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Dietary folate, but not choline, modifies neural tube defect risk in Shmt1 knockout mice.
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Am J Clin Nutr
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2011
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1.19
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13
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Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men.
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J Nutr
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2005
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1.17
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14
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Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk.
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2011
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1.16
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15
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Serine hydroxymethyltransferase anchors de novo thymidylate synthesis pathway to nuclear lamina for DNA synthesis.
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J Biol Chem
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2012
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1.16
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16
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Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism.
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J Biol Chem
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2008
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1.14
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17
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Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase.
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J Biol Chem
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2006
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1.13
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18
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A ferritin-responsive internal ribosome entry site regulates folate metabolism.
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J Biol Chem
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2007
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1.09
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19
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Methenyltetrahydrofolate synthetase regulates folate turnover and accumulation.
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J Biol Chem
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2003
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1.04
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20
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Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells.
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Arch Biochem Biophys
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2007
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1.01
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21
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Competition between sumoylation and ubiquitination of serine hydroxymethyltransferase 1 determines its nuclear localization and its accumulation in the nucleus.
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J Biol Chem
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2011
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1.01
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22
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A UV-responsive internal ribosome entry site enhances serine hydroxymethyltransferase 1 expression for DNA damage repair.
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J Biol Chem
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2009
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1.01
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23
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Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA.
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J Biol Chem
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2011
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0.99
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24
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Mechanism of the internal ribosome entry site-mediated translation of serine hydroxymethyltransferase 1.
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J Biol Chem
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2009
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0.99
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25
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Mimosine attenuates serine hydroxymethyltransferase transcription by chelating zinc. Implications for inhibition of DNA replication.
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J Biol Chem
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2004
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0.98
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26
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High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5.
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BMC Genet
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0.95
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27
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Modeling cellular compartmentation in one-carbon metabolism.
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Wiley Interdiscip Rev Syst Biol Med
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2013
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0.94
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28
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Convergence of genetic, nutritional and inflammatory factors in gastrointestinal cancers.
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2007
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0.89
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29
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Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration.
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J Nutr
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2012
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0.89
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30
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Cloning, expression, and purification of 5,10-methenyltetrahydrofolate synthetase from Mus musculus.
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2004
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5,10-Methenyltetrahydrofolate synthetase activity is increased in tumors and modifies the efficacy of antipurine LY309887.
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Arch Biochem Biophys
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2008
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0.89
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32
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Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice.
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2012
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0.88
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33
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Pyridoxal phosphate inhibits dynamic subunit interchange among serine hydroxymethyltransferase tetramers.
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J Biol Chem
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34
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Mthfs is an Essential Gene in Mice and a Component of the Purinosome.
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Front Genet
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35
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Mthfd1 is a modifier of chemically induced intestinal carcinogenesis.
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0.86
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36
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Supplemental dietary folic acid has no effect on chromosome damage in erythrocyte progenitor cells of mice.
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J Nutr
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2012
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0.82
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37
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Folate network genetic variation, plasma homocysteine, and global genomic methylation content: a genetic association study.
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BMC Med Genet
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0.82
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38
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Folate network genetic variation predicts cardiovascular disease risk in non-Hispanic white males.
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J Nutr
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2012
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0.80
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39
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Polymorphisms in serine hydroxymethyltransferase 1 and methylenetetrahydrofolate reductase interact to increase cardiovascular disease risk in humans.
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J Nutr
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2010
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0.80
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40
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Disruption of shmt1 impairs hippocampal neurogenesis and mnemonic function in mice.
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J Nutr
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2013
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0.79
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41
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Methenyltetrahydrofolate synthetase is a high-affinity catecholamine-binding protein.
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Arch Biochem Biophys
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0.78
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42
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Inhibition of 5,10-methenyltetrahydrofolate synthetase.
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43
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Folate supplementation in people with sickle cell disease.
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Nutritional regulation of epigenetic changes.
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Azoxymethane-induced colon carcinogenesis in mice occurs independently of de novo thymidylate synthesis capacity.
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J Nutr
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2014
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0.75
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