Yun-wu Zhang

Author PubWeight™ 17.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation. J Biol Chem 2007 1.91
2 Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome. Nat Med 2013 1.61
3 Proteolytic processing of Alzheimer's β-amyloid precursor protein. J Neurochem 2011 1.50
4 Pathological and physiological functions of presenilins. Mol Neurodegener 2006 1.38
5 Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid. J Neurosci 2012 1.02
6 Transcriptional regulation of PEN-2, a key component of the gamma-secretase complex, by CREB. Mol Cell Biol 2006 1.02
7 Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration. J Neurosci 2012 0.99
8 Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo. J Neurochem 2007 0.97
9 Salubrinal attenuates β-amyloid-induced neuronal death and microglial activation by inhibition of the NF-κB pathway. Neurobiol Aging 2011 0.89
10 Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing. Mol Neurodegener 2012 0.88
11 p53-dependent control of transactivation of the Pen2 promoter by presenilins. J Cell Sci 2009 0.82
12 Tumor suppressor PTEN affects tau phosphorylation: deficiency in the phosphatase activity of PTEN increases aggregation of an FTDP-17 mutant Tau. Mol Neurodegener 2006 0.82
13 Presenilins regulate the cellular level of the tumor suppressor PTEN. Neurobiol Aging 2007 0.80
14 M1 muscarinic acetylcholine receptor interacts with BACE1 and regulates its proteosomal degradation. Neurosci Lett 2012 0.80
15 Transcriptional regulation and its misregulation in Alzheimer's disease. Mol Brain 2013 0.79
16 Ferritin light chain interacts with PEN-2 and affects γ-secretase activity. Neurosci Lett 2013 0.79
17 Substrate check of gamma-secretase. Nat Struct Mol Biol 2010 0.77