Published in J Physiol on June 01, 1990
Pharmacokinetics and extrapulmonary beta 2 adrenoceptor activity of nebulised racemic salbutamol and its R and S isomers in healthy volunteers. Thorax (1997) 1.13
Enhancement of airway reactivity to histamine by isoprenaline and related beta-adrenoceptor agonists in the guinea-pig. Br J Pharmacol (1993) 0.84
Effects of a potassium channel opener (SDZ PCO 400) on guinea-pig and human pulmonary airways. Br J Pharmacol (1992) 0.84
Resistance to -adrenoceptor stimulants (a possible explanation for the rise in ashtma deaths). Br J Pharmacol (1971) 6.11
Mechanics of respiration in unanesthetized guinea pigs. Am J Physiol (1958) 5.21
Presynaptic regulation of the release of catecholamines. Pharmacol Rev (1980) 4.20
Isoprenaline resistance and the use of pressurised aerosols in asthma. Lancet (1968) 3.33
Iatrogenic asthma associated with adrenergic aerosols. Ann Intern Med (1966) 2.97
Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: a comparison between budesonide and terbutaline. J Allergy Clin Immunol (1985) 2.76
Effect of propranolol on ventilatory function. Am J Cardiol (1966) 2.73
Studies on the absorption, distribution and excretion of propranolol in rat, dog and monkey. J Pharmacol Exp Ther (1971) 2.34
The isolated stomach preparation of the mouse: a physiological unit for pharmacological analysis. Br J Pharmacol (1985) 2.25
Effect of long-term treatment with inhaled corticosteroids and beta-agonists on the bronchial responsiveness in children with asthma. J Allergy Clin Immunol (1987) 2.24
SElectivity of broncholidlator action of salbutamol in asthmatic patients. Br J Dis Chest (1971) 2.15
Catecholamine-induced subsensitivity of adenylate cyclase associated with loss of beta-adrenergic receptor binding sites. Proc Natl Acad Sci U S A (1975) 1.87
Airway response to salbutamol: effect of regular salbutamol inhalations in normal, atopic, and asthmatic subjects. Thorax (1982) 1.77
THE FATE OF 3H-ISO-PROTERENOL IN THE RAT. Biochem Pharmacol (1964) 1.77
In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, beta-adrenoceptor agonists and theophylline. Br J Clin Pharmacol (1986) 1.73
Uptake, metabolism and efflux of 14 C-5-hydroxytryptamine in isolated perfused rat lungs. J Pharmacol Exp Ther (1972) 1.53
An uptake of radioactivity from (plus or minus)-3H-isoprenaline and its inhibition by drugs which potentiate the responses to (minus)-isoprenaline in the guinea-pig isolated trachea. Br J Pharmacol (1969) 1.52
Decreased beta-adrenergic receptors on polymorphonuclear leukocytes after adrenergic therapy. N Engl J Med (1978) 1.51
The uptake and disposition of dl-norepinephrine in perfused rat lung. J Pharmacol Exp Ther (1969) 1.40
Airway and metabolic resistance to intravenous salbutamol: a study in normal man. Clin Sci (Lond) (1980) 1.33
Investigation of the mechanism of propranolol-induced bronchoconstriction. Br J Pharmacol (1979) 1.27
Accumulation of amines in the isolated perfused rabbit lung. J Pharmacol Exp Ther (1974) 1.23
Accumulation of 14 C-imipramine in isolated perfused rat lungs. J Pharmacol Exp Ther (1972) 1.23
Effects of labetalol and propranolol on histamine-induced bronchoconstriction in normal subjects. Br J Clin Pharmacol (1977) 1.17
Subsensitization of beta-adrenoceptors in airways and lymphocytes of healthy and asthmatic subjects. Am Rev Respir Dis (1982) 1.14
Tolerance to sympathomimetic bronchodilators in guinea-pig isolated lungs following chronic administration in vivo. Br J Pharmacol (1975) 0.97
Propranolol-induced airway hyperreactivity in guinea-pigs. Br J Pharmacol (1983) 0.96
Paradoxic bronchospasm after inhalation of isoptroterenol. Chest (1976) 0.89
Increased sensitivity to anaphylactic shock in guinea pigs induced by prolonged treatment with epinephrine prior to challenge. J Allergy (1971) 0.85
A comparative study of beta-adrenoceptors in human and porcine lung parenchyma strip. Br J Pharmacol (1982) 0.85
Effect of beta adrenergic blockage on bronchial sensitivity to inhaled acetylcholine in normal subjects. J Allergy Clin Immunol (1975) 0.84
In vivo desensitization to beta receptor mediated bronchodilator drugs in the rat: decreased beta receptor affinity. J Pharmacol Exp Ther (1978) 0.83
Increased responsiveness to histamine after propranolol in subjects with asthma nonresponsive to the bronchoconstrictive effect of propranolol. J Allergy Clin Immunol (1988) 0.83
The effect of prophylactic anti-asthma drugs on PAF-induced airway hyperreactivity. Jpn J Pharmacol (1989) 0.80
Parasympathetic ganglia in the airways. Bull Eur Physiopathol Respir (1986) 0.80
The effect of Paf antagonists on bronchial hyperresponsiveness induced by Paf, propranolol or indomethacin. Br J Pharmacol (1989) 0.77
Kinetics of extraneuronal uptake of isoprenaline in trachealis smooth muscle cells: comparison of rat and guinea-pig. J Pharm Pharmacol (1980) 0.77
"Lymphokines": non-antibody mediators of cellular immunity generated by lymphocyte activation. Nature (1969) 6.42
Prostaglandins as potentiators of increased vascular permeability in inflammation. Nature (1973) 6.34
Control of lymphokine secretion by prostaglandins. Nature (1976) 3.34
Carcinoma of the Stomach. Br Med J (1937) 2.34
Vasodilatation in the submaxillary gland of the cat. J Physiol (1965) 2.12
Visceral Pain. Br Med J (1937) 1.89
Proceedings: Role of prostaglandins in reactions of cellular immunity. Br J Pharmacol (1974) 1.67
Inflammatory actions of platelet activating factor (Pafacether) in guinea-pig skin. Br J Pharmacol (1983) 1.53
Prostaglandins and lymphokines in arthritis. Prostaglandins (1974) 1.52
The platelet in asthma. Lancet (1984) 1.50
Integration of reflectance confocal microscopy in sequential dermoscopy follow-up improves melanoma detection accuracy. Br J Dermatol (2014) 1.47
Impact of intramedullary instrumentation versus damage control for femoral fractures on immunoinflammatory parameters: prospective randomized analysis by the EPOFF Study Group. J Trauma (2003) 1.46
Evidence in man of synergistic interaction between putative mediators of acute inflammation and asthma. Lancet (1982) 1.45
Antigen challenge induces pulmonary airway eosinophil accumulation and airway hyperreactivity in sensitized guinea-pigs: the effect of anti-asthma drugs. Br J Pharmacol (1990) 1.45
Platelet-activating factor: a possible mediator of the dual response to allergen? Clin Allergy (1984) 1.45
Antiasthma drugs and airway hyperreactivity. Am Rev Respir Dis (1992) 1.38
An in vivo model for studying platelet aggregation and disaggregation. Thromb Haemost (1982) 1.33
An evaluation of cusum analysis in asthma. Br J Dis Chest (1980) 1.29
Measurement of rate of extravasation of plasma protein in inflammatory responses in guinea-pig skin using a continuous recording method. Br J Exp Pathol (1974) 1.26
Letter: An anti-inflammatory peptide from bee venom. Nature (1973) 1.23
Macrophages on intrauterine contraceptive devices produce prostaglandins. Nature (1975) 1.23
Inflammatory characteristics of platelet activating factor (PAF-acether) in human skin. Br J Dermatol (1984) 1.17
Eosinophil accumulation in pulmonary airways of guinea-pigs induced by exposure to an aerosol of platelet-activating factor: effect of anti-asthma drugs. Br J Pharmacol (1990) 1.14
Prospects for an oral Intal. Br J Dis Chest (1981) 1.14
Prostaglandin and thromboxane production by human and guinea-pig macrophages and leucocytes. Prostaglandins (1979) 1.14
Accumulation of inflammatory cells in response to intracutaneous platelet activating factor (Paf-acether) in man. Br J Dermatol (1985) 1.13
The late reaction following bronchial provocation with house dust mite allergen. Dependence on arachidonic acid metabolism. Clin Exp Immunol (1983) 1.10
Pulmonary edema induced by allergen challenge in the rat: noninvasive assessment by magnetic resonance imaging. Magn Reson Med (2001) 1.07
Proceedings: Inflammatory response produced by a factor released from lymphocytes. Br J Pharmacol (1972) 1.07
Asthma mortality and inhaled beta agonist therapy. Aust N Z J Med (1992) 1.05
Simultaneous measurements of the accumulation of isotope-labelled protein and erythrocytes in skin reactions of allergic inflammation in the guinea-pig. Immunology (1972) 1.05
Human recombinant lymphokines and cytokines induce pulmonary eosinophilia in the guinea pig which is inhibited by ketotifen and AH 21-132. Int Arch Allergy Appl Immunol (1990) 1.04
Prostaglandin production in arthritis. Ann Rheum Dis (1978) 1.04
Airway hyperreactivity. Lancet (1988) 1.02
Anti-inflammatory property of 401 (MCD-peptide), a peptide from the venom of the bee Apis mellifera (L.). Br J Pharmacol (1974) 0.99
Effects of serum albumin, indomethacin and histamine H1-antagonists on Paf-acether-induced inflammatory responses in the skin of experimental animals and man. Br J Pharmacol (1985) 0.98
Hyperresponsiveness of the airways following exposure of guinea-pigs to racemic mixtures and distomers of beta 2-selective sympathomimetics. Pulm Pharmacol (1994) 0.97
Accumulation of platelets and eosinophils in baboon lung after paf-acether challenge. Inhibition by ketotifen. Am Rev Respir Dis (1988) 0.97
Prostaglandins as regulators in cellular immunity. Prostaglandins Med (1978) 0.96
Cell migration inhibition: an appraisal. Acta Allergol (1974) 0.96
Cromoglycate (DSCG) inhibits responses to platelet-activating factor (PAF-acether) in man: an alternative mode of action for DSCG in asthma? Eur J Pharmacol (1982) 0.94
Exacerbation of airway hyperreactivity by (+/-)salbutamol in sensitized guinea pig. Jpn J Pharmacol (1993) 0.94
The relationship between inflammation and hyperreactivity of the airways in asthma. Clin Exp Allergy (1993) 0.94
Continuous monitoring of plasma protein extravasation and cell accumulation in vivo. Br J Dermatol (1983) 0.93
Allergic bronchospasm and airway hyperreactivity in the guinea pig. Jpn J Pharmacol (1993) 0.92
MRI of lung parenchyma in rats and mice using a gradient-echo sequence. NMR Biomed (2001) 0.91
Mode of action of sulphasalazine: an alternative view. Lancet (1982) 0.91
Carbohydrate metabolism in motor neurone disease. J Neurol Neurosurg Psychiatry (1977) 0.90
Effects of S-salbutamol on human isolated bronchus. Pulm Pharmacol Ther (1998) 0.89
Contrasting properties of albuterol stereoisomers. J Allergy Clin Immunol (1999) 0.89
Platelets and bronchospasm. Int Arch Allergy Appl Immunol (1984) 0.89
Cutaneous and pulmonary histopathological responses to platelet activating factor (Paf-acether) in the guinea-pig. J Pathol (1984) 0.89
Anti-allergy properties of PRD-92-Ea [5,5-dimethyl-11-oxo 5H, 11H-(2) benzopyrano (4,3-g) (1) benzopyran-9-carboxylic acid ethanolamine] [proceedings]. Br J Pharmacol (1978) 0.88
Effects of wortmannin on airways inflammation induced by allergen in actively sensitised Brown Norway rats. Eur J Pharmacol (2001) 0.88
Use of bio-resorbable implants for stabilisation of distal radius fractures: the United Kingdom patients' perspective. Injury (2005) 0.88
Leucocyte chemotactic activity in the parallel bioassay of guinea--pig lymphokines. Immunology (1977) 0.87
Somatostatin-like immunoreactivity in the retina. Proc Natl Acad Sci U S A (1980) 0.87
Melanoma detection in Italian pigmented lesion clinics. G Ital Dermatol Venereol (2014) 0.87
SDZ MKS 492. Agents Actions Suppl (1991) 0.86
The ventilatory and oxygen costs in the anesthetized rhesus monkey of inhaling drugs used in the therapy and diagnosis of asthma. Am Rev Respir Dis (1991) 0.85
Vitamin D supplementation in older adults: searching for specific guidelines in nursing homes. J Nutr Health Aging (2013) 0.85
Effects of a potassium channel opener (SDZ PCO 400) on guinea-pig and human pulmonary airways. Br J Pharmacol (1992) 0.84
Evidence for an atypical receptor mediating the augmented bronchoconstrictor response to adenosine induced by allergen challenge in actively sensitized Brown Norway rats. Br J Pharmacol (2002) 0.84
Platelets in asthma. Lancet (1985) 0.84
Inhibition of PAF-induced eosinophil accumulation in pulmonary airways of guinea pigs by anti-asthma drugs. Jpn J Pharmacol (1989) 0.84
Selective airway responsiveness in asthma. Trends Pharmacol Sci (1999) 0.83
Mechanism of airway hyperresponsiveness to adenosine induced by allergen challenge in actively sensitized Brown Norway rats. Br J Pharmacol (2001) 0.83
Allergy to tetracosactrin-depot. Lancet (1971) 0.83
Defective PGE reactivity in leucocytes of multiple sclerosis patients. Prostaglandins (1976) 0.83
Modulation by cyclosporin-A of mononuclear cell distribution during experimental allergic encephalomyelitis. Int J Immunopharmacol (1984) 0.83
Active enantiomers may cause adverse effects in asthma. Trends Pharmacol Sci (1992) 0.83
Effects of ketotifen upon responses to platelet activating factor: a basis for asthma prophylaxis. Ann Allergy (1986) 0.82
Prostaglandins and lymphokines in inflammation. Rheumatol Rehabil (1978) 0.82
Pretreatment with rh-GMCSF, but not rh-IL3, enhances PAF-induced eosinophil accumulation in guinea-pig airways. Br J Pharmacol (1990) 0.82
Palladium-catalyzed cross-coupling reactions for the synthesis of 6, 8-disubstituted 1,7-naphthyridines: a novel class of potent and selective phosphodiesterase type 4D inhibitors. J Med Chem (2000) 0.82
Differential responses of asthmatic airways to enantiomers of albuterol. Implications for clinical treatment of asthma. Clin Rev Allergy Immunol (1996) 0.82
A placebo-controlled, double-blind crossover study of naltrexone hydrochloride in outpatients with normal weight bulimia. J Clin Psychopharmacol (1989) 0.82
Mechanisms of inhibition by cyclosporin A on pulmonary leukocyte accumulation. Trends Pharmacol Sci (1994) 0.81
Designing pharmaceutical trials for sarcopenia in frail older adults: EU/US Task Force recommendations. J Nutr Health Aging (2013) 0.81
Regulation of allergic responses by prostaglandins: a review. J R Soc Med (1980) 0.81
Identification, preparation, and characterization of several polymorphs and solvates of terazosin hydrochloride. J Pharm Sci (2006) 0.81
Sunbed use among subjects at high risk of melanoma: an Italian survey after the ban. Br J Dermatol (2013) 0.81
Use of radioactiv isotopes for continuous recording of increased vascular permeability in the rabbit ear. J Physiol (1970) 0.80
Anti-inflammatory drug actions on allergic responses in guinea-pig skin. Agents Actions (1978) 0.80
beta-Adrenergic tachyphylaxis in the rat and its reversal and prevention by ketotifen. Eur J Pharmacol (1983) 0.80
Pharmacology of the late response to allergen and its relevance to asthma prophylaxis. Int Arch Allergy Appl Immunol (1985) 0.80
Inflammatory cell accumulation in response to intracutaneous Paf-acether: a mediator of acute and persistent inflammation? Br J Dermatol (1985) 0.80
Development of airway hyperreactivity in the guinea-pig following allergic reactions. Agents Actions Suppl (1991) 0.80
The effect of prophylactic anti-asthma drugs on PAF-induced airway hyperreactivity. Jpn J Pharmacol (1989) 0.80
Pharmacological properties of a proposed mediator of dealyed hypersensitivity reactions. Int Arch Allergy Appl Immunol (1973) 0.79