Published in J Pineal Res on December 05, 2011
CHOCOlate MeLatonin for AdolescenT MigrainE (CHOCOLATE) | NCT03597529
Melatonin: buffering the immune system. Int J Mol Sci (2013) 1.11
Therapeutic applications of melatonin. Ther Adv Endocrinol Metab (2013) 0.89
Analgesic, anxiolytic and anaesthetic effects of melatonin: new potential uses in pediatrics. Int J Mol Sci (2015) 0.87
Antenatal melatonin as an antioxidant in human pregnancies complicated by fetal growth restriction--a phase I pilot clinical trial: study protocol. BMJ Open (2013) 0.86
New role of JAK2/STAT3 signaling in endothelial cell oxidative stress injury and protective effect of melatonin. PLoS One (2013) 0.86
Sleep deprivation aggravates median nerve injury-induced neuropathic pain and enhances microglial activation by suppressing melatonin secretion. Sleep (2014) 0.82
Analgesic effects of melatonin on post-herpetic neuralgia. Int J Clin Exp Med (2015) 0.78
Expression of melatonin synthesizing enzymes in Helicobacter pylori infected gastric mucosa. Biomed Res Int (2013) 0.78
Is melatonin the next "new" therapy to improve sleep and reduce pain? Sleep (2014) 0.75
The Role of Melatonin in the Treatment of Primary Headache Disorders. Headache (2016) 0.75
Neonatal analgesia: A neglected issue in the tropics. Niger Med J (2014) 0.75
Dietary Sources and Bioactivities of Melatonin. Nutrients (2017) 0.75
Infant Colic. Semin Pediatr Neurol (2015) 0.75
Premedication with melatonin vs midazolam: efficacy on anxiety and compliance in paediatric surgical patients. Eur J Pediatr (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Introduction of gluten, HLA status, and the risk of celiac disease in children. N Engl J Med (2014) 4.64
Effect of thalidomide on clinical remission in children and adolescents with refractory Crohn disease: a randomized clinical trial. JAMA (2013) 3.67
Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res (2004) 2.87
One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? J Pineal Res (2007) 2.84
Melatonin as a natural ally against oxidative stress: a physicochemical examination. J Pineal Res (2011) 2.12
Melatonin: from basic research to cancer treatment clinics. J Clin Oncol (2002) 1.99
Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. Curr Top Med Chem (2002) 1.75
On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK. J Pineal Res (2012) 1.60
A review of the multiple actions of melatonin on the immune system. Endocrine (2005) 1.55
Melatonin reduces the severity of anesthesia-induced apoptotic neurodegeneration in the developing rat brain. Neurobiol Dis (2005) 1.52
Melatonin membrane receptors in peripheral tissues: distribution and functions. Mol Cell Endocrinol (2012) 1.47
R298Q mutation of p63 gene in autosomal dominant ectodermal dysplasia associated with arrhythmogenic right ventricular cardiomyopathy. Eur J Med Genet (2008) 1.45
First intention high-frequency oscillatory and conventional mechanical ventilation in premature infants without antenatal glucocorticoid prophylaxis. Pediatr Crit Care Med (2012) 1.40
Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate. J Pineal Res (2008) 1.40
Extrapineal melatonin: sources, regulation, and potential functions. Cell Mol Life Sci (2014) 1.31
Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. J Pineal Res (2009) 1.29
Melatonin and the ovary: physiological and pathophysiological implications. Fertil Steril (2008) 1.29
Melatonin mitigates mitochondrial malfunction. J Pineal Res (2005) 1.27
Causes of oxidative stress in the pre- and perinatal period. Biol Neonate (2002) 1.26
Melatonin as a radioprotective agent: a review. Int J Radiat Oncol Biol Phys (2004) 1.25
Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin. J Pineal Res (2003) 1.23
Melatonin-immune system relationships. Curr Top Med Chem (2002) 1.21
A review of the molecular aspects of melatonin's anti-inflammatory actions: recent insights and new perspectives. J Pineal Res (2012) 1.21
Oxidative stress of the newborn in the pre- and postnatal period and the clinical utility of melatonin. J Pineal Res (2008) 1.21
Melatonin and mitochondrial function. Life Sci (2004) 1.20
Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review. J Pineal Res (2014) 1.20
Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling. J Pineal Res (2011) 1.20
Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies. J Pineal Res (2011) 1.19
Functional roles of melatonin in plants, and perspectives in nutritional and agricultural science. J Exp Bot (2011) 1.19
Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations. J Pineal Res (2011) 1.18
Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance. FASEB J (2004) 1.17
Melatonin and pregnancy in the human. Reprod Toxicol (2008) 1.17
Defining chronodisruption. J Pineal Res (2009) 1.17
Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes. J Pineal Res (2012) 1.15
Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages. J Neuroimmunol (2005) 1.14
Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats. J Pineal Res (2007) 1.11
Shift work and cancer: the evidence and the challenge. Dtsch Arztebl Int (2010) 1.10
Cardiovascular diseases: protective effects of melatonin. J Pineal Res (2008) 1.10
Phytomelatonin: a review. J Exp Bot (2008) 1.09
Pediatric idiopathic intracranial hypertension and extreme childhood obesity: a role for weight gain. J Pediatr (2013) 1.09
Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism. Prostate (2005) 1.08
Chronodisruption and cancer. Naturwissenschaften (2008) 1.08
Melatonin alleviates lung damage induced by the chemical warfare agent nitrogen mustard. Toxicol Lett (2007) 1.08
Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis. J Pineal Res (2007) 1.07
Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1. FASEB J (2003) 1.07
The RNA-seq approach to discriminate gene expression profiles in response to melatonin on cucumber lateral root formation. J Pineal Res (2013) 1.07
Mechanisms of cancer inhibition by melatonin. J Pineal Res (2004) 1.06
Melatonin-mitochondria interplay in health and disease. Curr Top Med Chem (2011) 1.06
Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice. J Pineal Res (2005) 1.06
Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes. J Pineal Res (2004) 1.05
Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice. J Pineal Res (2008) 1.05
Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease. J Pineal Res (2010) 1.04
Melatonin as an antioxidant: physiology versus pharmacology. J Pineal Res (2005) 1.03
Melatonin: an established antioxidant worthy of use in clinical trials. Mol Med (2008) 1.03
Role of melatonin in metabolic regulation. Rev Endocr Metab Disord (2009) 1.03
Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair. Exp Dermatol (2008) 1.03
Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer. J Pineal Res (2010) 1.02
Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells. FASEB J (2013) 1.02
Melatonin and circadian biology in human cardiovascular disease. J Pineal Res (2010) 1.01
The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors. J Pineal Res (2010) 1.01
Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a review. Expert Opin Ther Targets (2013) 1.00
A generalized theory of carcinogenesis due to chronodisruption. Neuro Endocrinol Lett (2008) 1.00
Stress response and procedural pain in the preterm newborn: the role of pharmacological and non-pharmacological treatments. Eur J Pediatr (2011) 1.00
Prophylactic effect of melatonin in reducing lead-induced neurotoxicity in the rat. Cell Mol Biol Lett (2003) 0.99
Light, timing of biological rhythms, and chronodisruption in man. Naturwissenschaften (2003) 0.99
The changing biological roles of melatonin during evolution: from an antioxidant to signals of darkness, sexual selection and fitness. Biol Rev Camb Philos Soc (2009) 0.99
Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction. Redox Rep (2003) 0.98
Clinical significance of NOD2/CARD15 and Toll-like receptor 4 gene single nucleotide polymorphisms in inflammatory bowel disease. World J Gastroenterol (2008) 0.98
Relationship of blood lead levels to blood pressure in exhaust battery storage workers. Ind Health (2006) 0.98
AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail. J Pineal Res (2013) 0.98
Oxidative and inflammatory parameters in respiratory distress syndrome of preterm newborns: beneficial effects of melatonin. Am J Perinatol (2004) 0.98
Melatonin and tryptophan affect the activity-rest rhythm, core and peripheral temperatures, and interleukin levels in the ringdove: changes with age. J Gerontol A Biol Sci Med Sci (2009) 0.98
Melatonin resynchronizes dysregulated circadian rhythm circuitry in human prostate cancer cells. J Pineal Res (2010) 0.97
Frequency of Hashimoto's thyroiditis antecedents in the history of children and adolescents with graves' disease. Horm Res Paediatr (2010) 0.97
Melatonin: potential functions in the oral cavity. J Periodontol (2007) 0.97
Melatonin counteracts inducible mitochondrial nitric oxide synthase-dependent mitochondrial dysfunction in skeletal muscle of septic mice. J Pineal Res (2006) 0.97
Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells. J Pineal Res (2009) 0.96
Melatonin inhibits free radical-mediated mitochondrial-dependent hepatocyte apoptosis and liver damage induced during malarial infection. J Pineal Res (2007) 0.96
Exogenously applied melatonin stimulates root growth and raises endogenous indoleacetic acid in roots of etiolated seedlings of Brassica juncea. J Plant Physiol (2008) 0.96
Melatonin protects against isoproterenol-induced myocardial injury in the rat: antioxidative mechanisms. J Pineal Res (2010) 0.96
Novel rhythms of N1-acetyl-N2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation. FASEB J (2007) 0.95
Melatonin decreases cell proliferation and induces melanogenesis in human melanoma SK-MEL-1 cells. J Pineal Res (2010) 0.95
Pharmacokinetics of orally administered melatonin in critically ill patients. J Pineal Res (2010) 0.95
Exercise and melatonin in humans: reciprocal benefits. J Pineal Res (2011) 0.95
Melatonin inhibits telomerase activity in the MCF-7 tumor cell line both in vivo and in vitro. J Pineal Res (2003) 0.95
Alzheimer's disease: pathological mechanisms and the beneficial role of melatonin. J Pineal Res (2011) 0.95
Protective effects of melatonin in experimental free radical-related ocular diseases. J Pineal Res (2006) 0.94
Melatonin promotes the in vitro development of pronuclear embryos and increases the efficiency of blastocyst implantation in murine. J Pineal Res (2013) 0.94
Bispectral Index in ICU: correlation with Ramsay Score on assessment of sedation level. J Clin Monit Comput (2002) 0.94
SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin. Autophagy (2015) 0.94