Melatonin as an antioxidant: physiology versus pharmacology.

Melatonin: an established antioxidant worthy of use in clinical trials. Mol Med (2008) 1.03

Diaphragmatic breathing reduces exercise-induced oxidative stress. Evid Based Complement Alternat Med (2011) 1.01

Aquaporin 1 - a novel player in spinal cord injury. J Neurochem (2008) 0.96

Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp-9) and effector caspases (casp-3/casp-7) and PARP in UVR-exposed HaCaT keratinocytes. J Pineal Res (2007) 0.92

Melatonin modulates the severity of taurocholate-induced acute pancreatitis in the rat. Dig Dis Sci (2009) 0.87

Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances, but does not improve the sleeping problems. J Assist Reprod Genet (2011) 0.87

Abnormal Skeletal Growth in Adolescent Idiopathic Scoliosis Is Associated with Abnormal Quantitative Expression of Melatonin Receptor, MT2. Int J Mol Sci (2013) 0.83

Melatonin represses oxidative stress-induced activation of the MAP kinase and mTOR signaling pathways in H4IIE hepatoma cells through inhibition of Ras. J Pineal Res (2008) 0.83

The circadian control of skin and cutaneous photodamage. Photochem Photobiol (2012) 0.81

Melatonin-Producing Endophytic Bacteria from Grapevine Roots Promote the Abiotic Stress-Induced Production of Endogenous Melatonin in Their Hosts. Front Plant Sci (2016) 0.81

Effect of a combined treatment with erythropoietin and melatonin on renal ischemia reperfusion injury in male rats. Clin Exp Nephrol (2014) 0.80

Melatonin and human skin aging. Dermatoendocrinol (2012) 0.79

Melatonin effect during different maturation stages of oocyte and subsequent embryo development in mice. Iran J Reprod Med (2013) 0.78

Melatonin: Pharmacology, Functions and Therapeutic Benefits. Curr Neuropharmacol (2017) 0.77

Mitochondria Synthesize Melatonin to Ameliorate Its Function and Improve Mice Oocyte's Quality under in Vitro Conditions. Int J Mol Sci (2016) 0.77

Melatonin treatment results in regression of endometriotic lesions in an ooferectomized rat endometriosis model. J Turk Ger Gynecol Assoc (2013) 0.77

Metabolomics analysis reveals insights into biochemical mechanisms of mental stress-induced left ventricular dysfunction. Metabolomics (2015) 0.76

Melatonin and its correlation with testosterone in polycystic ovarian syndrome. J Hum Reprod Sci (2013) 0.75

Melatonin attenuates intermittent hypoxia-induced lipid peroxidation and local inflammation in rat adrenal medulla. Int J Mol Sci (2014) 0.75

Utilizing melatonin to combat bacterial infections and septic injury. Br J Pharmacol (2017) 0.75

The combination of letrozole and melatonin causes regression in size not histopathological scores on endometriosis in an experimental rat model. J Turk Ger Gynecol Assoc (2009) 0.75

Melatonin implantation improved the egg-laying rate and quality in hens past their peak egg-laying age. Sci Rep (2016) 0.75

Melatonin modulates drug-induced acute porphyria. Toxicol Rep (2016) 0.75

Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08

Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res (2004) 2.87

One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? J Pineal Res (2007) 2.84

Melatonin as a natural ally against oxidative stress: a physicochemical examination. J Pineal Res (2011) 2.12

Melatonin: from basic research to cancer treatment clinics. J Clin Oncol (2002) 1.99

Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. Curr Top Med Chem (2002) 1.75

On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK. J Pineal Res (2012) 1.60

A review of the multiple actions of melatonin on the immune system. Endocrine (2005) 1.55

Melatonin reduces the severity of anesthesia-induced apoptotic neurodegeneration in the developing rat brain. Neurobiol Dis (2005) 1.52

Melatonin membrane receptors in peripheral tissues: distribution and functions. Mol Cell Endocrinol (2012) 1.47

Melatonin: a multitasking molecule. Prog Brain Res (2010) 1.46

Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate. J Pineal Res (2008) 1.40

Extrapineal melatonin: sources, regulation, and potential functions. Cell Mol Life Sci (2014) 1.31

Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans. Acta Biochim Pol (2003) 1.30

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. J Pineal Res (2009) 1.29

Melatonin and the ovary: physiological and pathophysiological implications. Fertil Steril (2008) 1.29

Melatonin mitigates mitochondrial malfunction. J Pineal Res (2005) 1.27

Causes of oxidative stress in the pre- and perinatal period. Biol Neonate (2002) 1.26

Melatonin as a radioprotective agent: a review. Int J Radiat Oncol Biol Phys (2004) 1.25

Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin. J Pineal Res (2003) 1.23

Melatonin: reducing the toxicity and increasing the efficacy of drugs. J Pharm Pharmacol (2002) 1.23

A review of the molecular aspects of melatonin's anti-inflammatory actions: recent insights and new perspectives. J Pineal Res (2012) 1.21

Oxidative stress of the newborn in the pre- and postnatal period and the clinical utility of melatonin. J Pineal Res (2008) 1.21

Melatonin-immune system relationships. Curr Top Med Chem (2002) 1.21

Melatonin and mitochondrial function. Life Sci (2004) 1.20

Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review. J Pineal Res (2014) 1.20

Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling. J Pineal Res (2011) 1.20

Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies. J Pineal Res (2011) 1.19

Functional roles of melatonin in plants, and perspectives in nutritional and agricultural science. J Exp Bot (2011) 1.19

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations. J Pineal Res (2011) 1.18

Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance. FASEB J (2004) 1.17

Melatonin and pregnancy in the human. Reprod Toxicol (2008) 1.17

Defining chronodisruption. J Pineal Res (2009) 1.17

Melatonin: a novel protective agent against oxidative injury of the ischemic/reperfused heart. Cardiovasc Res (2003) 1.15

Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes. J Pineal Res (2012) 1.15

Melatonin and reproduction revisited. Biol Reprod (2009) 1.14

Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages. J Neuroimmunol (2005) 1.14

Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats. J Pineal Res (2007) 1.11

Shift work and cancer: the evidence and the challenge. Dtsch Arztebl Int (2010) 1.10

Cardiovascular diseases: protective effects of melatonin. J Pineal Res (2008) 1.10

Phytomelatonin: a review. J Exp Bot (2008) 1.09

Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism. Prostate (2005) 1.08

Chronodisruption and cancer. Naturwissenschaften (2008) 1.08

Melatonin alleviates lung damage induced by the chemical warfare agent nitrogen mustard. Toxicol Lett (2007) 1.08

Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis. J Pineal Res (2007) 1.07

Melatonin and its potential biological functions in the fruits of sweet cherry. J Pineal Res (2013) 1.07

Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1. FASEB J (2003) 1.07

The RNA-seq approach to discriminate gene expression profiles in response to melatonin on cucumber lateral root formation. J Pineal Res (2013) 1.07

Mechanisms of cancer inhibition by melatonin. J Pineal Res (2004) 1.06

Melatonin-mitochondria interplay in health and disease. Curr Top Med Chem (2011) 1.06

When melatonin gets on your nerves: its beneficial actions in experimental models of stroke. Exp Biol Med (Maywood) (2005) 1.06

Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice. J Pineal Res (2005) 1.06

Light at night, chronodisruption, melatonin suppression, and cancer risk: a review. Crit Rev Oncog (2007) 1.05

Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes. J Pineal Res (2004) 1.05

Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice. J Pineal Res (2008) 1.05

Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease. J Pineal Res (2010) 1.04

Melatonin: an established antioxidant worthy of use in clinical trials. Mol Med (2008) 1.03

Role of melatonin in metabolic regulation. Rev Endocr Metab Disord (2009) 1.03

Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair. Exp Dermatol (2008) 1.03

Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer. J Pineal Res (2010) 1.02

Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells. FASEB J (2013) 1.02

Melatonin and circadian biology in human cardiovascular disease. J Pineal Res (2010) 1.01

The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors. J Pineal Res (2010) 1.01

Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a review. Expert Opin Ther Targets (2013) 1.00

A generalized theory of carcinogenesis due to chronodisruption. Neuro Endocrinol Lett (2008) 1.00

Stress response and procedural pain in the preterm newborn: the role of pharmacological and non-pharmacological treatments. Eur J Pediatr (2011) 1.00

Prophylactic effect of melatonin in reducing lead-induced neurotoxicity in the rat. Cell Mol Biol Lett (2003) 0.99

Light, timing of biological rhythms, and chronodisruption in man. Naturwissenschaften (2003) 0.99

The changing biological roles of melatonin during evolution: from an antioxidant to signals of darkness, sexual selection and fitness. Biol Rev Camb Philos Soc (2009) 0.99

Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction. Redox Rep (2003) 0.98

AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail. J Pineal Res (2013) 0.98

Melatonin and tryptophan affect the activity-rest rhythm, core and peripheral temperatures, and interleukin levels in the ringdove: changes with age. J Gerontol A Biol Sci Med Sci (2009) 0.98

Oxidative and inflammatory parameters in respiratory distress syndrome of preterm newborns: beneficial effects of melatonin. Am J Perinatol (2004) 0.98

The universal nature, unequal distribution and antioxidant functions of melatonin and its derivatives. Mini Rev Med Chem (2013) 0.98

Obesity and metabolic syndrome: association with chronodisruption, sleep deprivation, and melatonin suppression. Ann Med (2011) 0.98

Neurotoxins: free radical mechanisms and melatonin protection. Curr Neuropharmacol (2010) 0.97

Pain in neonatal intensive care: role of melatonin as an analgesic antioxidant. J Pineal Res (2011) 0.97

Melatonin: potential functions in the oral cavity. J Periodontol (2007) 0.97

Melatonin resynchronizes dysregulated circadian rhythm circuitry in human prostate cancer cells. J Pineal Res (2010) 0.97

Melatonin counteracts inducible mitochondrial nitric oxide synthase-dependent mitochondrial dysfunction in skeletal muscle of septic mice. J Pineal Res (2006) 0.97

Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells. J Pineal Res (2009) 0.96

Exogenously applied melatonin stimulates root growth and raises endogenous indoleacetic acid in roots of etiolated seedlings of Brassica juncea. J Plant Physiol (2008) 0.96

Melatonin protects against isoproterenol-induced myocardial injury in the rat: antioxidative mechanisms. J Pineal Res (2010) 0.96

Melatonin inhibits free radical-mediated mitochondrial-dependent hepatocyte apoptosis and liver damage induced during malarial infection. J Pineal Res (2007) 0.96