Inhibition of membrane Na+ channels by A type botulinum toxin at femtomolar concentrations in central and peripheral neurons.

PubWeight™: 0.87‹?›

🔗 View Article (PMID 22156364)

Published in J Pharmacol Sci on December 10, 2011

Authors

Min-Chul Shin1, Masahito Wakita, Du-Jie Xie, Toshitaka Yamaga, Satomi Iwata, Yasushi Torii, Tetsuhiro Harakawa, Akihiro Ginnaga, Shunji Kozaki, Norio Akaike

Author Affiliations

1: Research Division for Life Sciences, Kumamoto Health Science University, Japan.

Articles by these authors

Reduction of KCC2 expression and GABAA receptor-mediated excitation after in vivo axonal injury. J Neurosci (2002) 1.58

A novel M cell-specific carbohydrate-targeted mucosal vaccine effectively induces antigen-specific immune responses. J Exp Med (2007) 1.47

Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines. Nat Mater (2010) 1.45

Characterization of the neurotoxin produced by isolates associated with avian botulism. Avian Dis (2005) 1.39

Functional changes in piriform cortex pyramidal neurons in the chronic methamphetamine-treated rat. Gen Physiol Biophys (2014) 1.38

Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins. J Biol Chem (2005) 1.37

Properties of corynephage attachment site and molecular epidemiology of Corynebacterium ulcerans isolated from humans and animals in Japan. Jpn J Infect Dis (2008) 1.35

De Novo mutations in GNAO1, encoding a Gαo subunit of heterotrimeric G proteins, cause epileptic encephalopathy. Am J Hum Genet (2013) 1.27

Altered emotional behavioral responses in mice lacking brain-type fatty acid-binding protein gene. Eur J Neurosci (2006) 1.26

Genetic characterization of Clostridium botulinum associated with type B infant botulism in Japan. J Clin Microbiol (2009) 1.21

GABAA receptor phospho-dependent modulation is regulated by phospholipase C-related inactive protein type 1, a novel protein phosphatase 1 anchoring protein. J Neurosci (2004) 1.17

Sequence of the gene for Clostridium botulinum type B neurotoxin associated with infant botulism, expression of the C-terminal half of heavy chain and its binding activity. Biochim Biophys Acta (2003) 1.14

Characterization of the D/C mosaic neurotoxin produced by Clostridium botulinum associated with bovine botulism in Japan. Vet Microbiol (2009) 1.12

Brain-derived neurotrophic factor regulates surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid receptors by enhancing the N-ethylmaleimide-sensitive factor/GluR2 interaction in developing neocortical neurons. J Biol Chem (2002) 1.12

Role of the PLC-related, catalytically inactive protein p130 in GABA(A) receptor function. EMBO J (2002) 1.08

alpha 2-Adrenoceptor-mediated presynaptic modulation of GABAergic transmission in mechanically dissociated rat ventrolateral preoptic neurons. J Neurophysiol (2003) 1.06

Transsynaptic inhibition of spinal transmission by A2 botulinum toxin. J Physiol (2012) 1.01

Cytokine-induced enhancement of calcium-dependent glutamate release from astrocytes mediated by nitric oxide. Neurosci Lett (2007) 1.00

Differential distributions of the Ca2+ -dependent activator protein for secretion family proteins (CAPS2 and CAPS1) in the mouse brain. J Comp Neurol (2006) 0.97

Identification of the receptor-binding sites in the carboxyl-terminal half of the heavy chain of botulinum neurotoxin types C and D. Microb Pathog (2008) 0.96

Biochemical and molecular characterization of minor serogroups of Shiga toxin-producing Escherichia coli isolated from humans in Osaka prefecture. J Vet Med Sci (2007) 0.95

A novel neurotoxoid vaccine prevents mucosal botulism. J Immunol (2005) 0.95

Two Japanese Corynebacterium ulcerans isolates from the same hospital: ribotype, toxigenicity and serum antitoxin titre. J Med Microbiol (2010) 0.95

Comparison of effects of botulinum toxin subtype A1 and A2 using twitch tension assay and rat grip strength test. Toxicon (2010) 0.94

Activation of presynaptic glycine receptors facilitates glycine release from presynaptic terminals synapsing onto rat spinal sacral dorsal commissural nucleus neurons. J Physiol (2003) 0.94

Adenosine A1 receptor-mediated presynaptic inhibition of GABAergic transmission in immature rat hippocampal CA1 neurons. J Neurophysiol (2003) 0.94

Type A1 but not type A2 botulinum toxin decreases the grip strength of the contralateral foreleg through axonal transport from the toxin-treated foreleg of rats. J Pharmacol Sci (2011) 0.92

The Na(+)/H(+) exchanger is a major pH regulator in GABAergic presynaptic nerve terminals synapsing onto rat CA3 pyramidal neurons. J Neurochem (2006) 0.92

Mucosal vaccine targeting improves onset of mucosal and systemic immunity to botulinum neurotoxin A. J Immunol (2006) 0.91

Functional roles of presynaptic GABA(A) receptors on glycinergic nerve terminals in the rat spinal cord. J Physiol (2002) 0.91

Alpha 1-adrenoceptor-activated cation currents in neurones acutely isolated from rat cardiac parasympathetic ganglia. J Physiol (2003) 0.90

The effects of volatile anesthetics on synaptic and extrasynaptic GABA-induced neurotransmission. Brain Res Bull (2012) 0.90

Effects of ethanol on GABA(A) receptors in GABAergic and glutamatergic presynaptic nerve terminals. J Pharmacol Exp Ther (2012) 0.88

Circadian rhythm in intracellular Cl(-) activity of acutely dissociated neurons of suprachiasmatic nucleus. Am J Physiol Cell Physiol (2002) 0.88

Identification of 5-HT receptor subtypes enhancing inhibitory transmission in the rat spinal dorsal horn in vitro. Mol Pain (2012) 0.87

Structural and mutational analyses of the receptor binding domain of botulinum D/C mosaic neurotoxin: insight into the ganglioside binding mechanism. Biochem Biophys Res Commun (2011) 0.87

Pre- and postsynaptic ATP-sensitive potassium channels during metabolic inhibition of rat hippocampal CA1 neurons. J Physiol (2002) 0.87

Characterization of Clostridium butyricum neurotoxin associated with food-borne botulism. Microb Pathog (2002) 0.87

Determination of the glycosaminoglycan-protein linkage region oligosaccharide structures of proteoglycans from Drosophila melanogaster and Caenorhabditis elegans. J Biol Chem (2002) 0.87

Involvement of the C-terminal tail of Arthrobacter ureafaciens sialidase isoenzyme M in cleavage of the internal sialic acid of ganglioside GM1. J Biochem (2005) 0.87

Syntaxin 1B suppresses macropinocytosis and semaphorin 3A-induced growth cone collapse. J Neurosci (2011) 0.86

Effects of A2 type botulinum toxin on spontaneous miniature and evoked transmitter release from the rat spinal excitatory and inhibitory synapses. Toxicon (2010) 0.86

Modulation of allopregnanolone on excitatory transmitters release from single glutamatergic terminal. Brain Res Bull (2012) 0.85

GABAB receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert. J Physiol (2003) 0.85

Production and immunogenic efficacy of botulinum tetravalent (A, B, E, F) toxoid. Vaccine (2002) 0.85

Calcium channel subtypes on single GABAergic presynaptic terminal projecting to rat hippocampal neurons. Brain Res (2002) 0.84

Multiplex PCRs for assignment of Staphylocoagulase types and subtypes of type VI Staphylocoagulase. J Microbiol Methods (2008) 0.84

Role of presynaptic 5-HT1A and 5-HT3 receptors in modulation of synaptic GABA transmission in dissociated rat basolateral amygdala neurons. Life Sci (2002) 0.84

Quantitative analysis of toxin extracts from various tissues of wild and cultured puffer fish by an electrophysiological method. Toxicon (2007) 0.83

Possible roles of kainate receptors on GABAergic nerve terminals projecting to rat substantia nigra dopaminergic neurons. J Neurophysiol (2003) 0.83

Inhibition of Na currents by the toxin extracts from puffer fishes captured in the sea coast of Japan. Toxicon (2010) 0.83

Protective effect of botulinum C/D mosaic toxoid against avian botulism. J Vet Med Sci (2006) 0.83

Location of the primary gustatory area in humans and its properties, studied by magnetoencephalography. Chem Senses (2005) 0.82

Unique biological activity of botulinum D/C mosaic neurotoxin in murine species. Infect Immun (2012) 0.82

RNAi suppression of rice endogenous storage proteins enhances the production of rice-based Botulinum neutrotoxin type A vaccine. Vaccine (2012) 0.82

Inhibition of nitric oxide production and inducible nitric oxide synthase expression by a polymethoxyflavone from young fruits of Citrus unshiu in rat primary astrocytes. Biosci Biotechnol Biochem (2012) 0.82

Improved detection methods by genetic and immunological techniques for botulinum C/D and D/C mosaic neurotoxins. Vet Microbiol (2012) 0.82

Effects of propofol on GABAergic and glutamatergic transmission in isolated hippocampal single nerve-synapse preparations. Eur J Pharmacol (2013) 0.82

Synaptic vesicle chips to assay botulinum neurotoxins. Biochem J (2005) 0.82

Diversity of neuron-specific K+-Cl- cotransporter expression and inhibitory postsynaptic potential depression in rat motoneurons. J Biol Chem (2001) 0.82

Visualization of gaseous monoxide reception by soluble guanylate cyclase in the rat retina. FASEB J (2003) 0.82

Cytotoxicity of Clostridium septicum alpha-toxin: its oligomerization in detergent resistant membranes of mammalian cells. Microb Pathog (2004) 0.81

Reduced NR2A expression and prolonged decay of NMDA receptor-mediated synaptic current in rat vagal motoneurons following axotomy. J Physiol (2002) 0.81

Allopregnanolone enhancement of GABAergic transmission in rat medial preoptic area neurons. Am J Physiol Endocrinol Metab (2002) 0.81

Differential modulation of evoked and spontaneous glycine release from rat spinal cord glycinergic terminals by the cyclic AMP/protein kinase A transduction cascade. J Neurochem (2004) 0.81

Effects of various K+ channel blockers on spontaneous glycine release at rat spinal neurons. Brain Res (2007) 0.81

Effects of polyamines on two strains of Trypanosoma brucei in infected rats and in vitro culture. J Parasitol (2006) 0.81

P19 embryonal carcinoma cells exhibit high sensitivity to botulinum type C and D/C mosaic neurotoxins. Microbiol Immunol (2012) 0.81

Accumulation of GABAergic neurons, causing a focal ambient GABA gradient, and downregulation of KCC2 are induced during microgyrus formation in a mouse model of polymicrogyria. Cereb Cortex (2012) 0.80

A novel multiplex PCR method for Clostridium botulinum neurotoxin type A gene cluster typing. Microbiol Immunol (2010) 0.80

Specificity of botulinum protease for human VAMP family proteins. Microbiol Immunol (2012) 0.80

Detection of Salmonella invA by isothermal and chimeric primer-initiated amplification of nucleic acids (ICAN) in Zambia. Comp Immunol Microbiol Infect Dis (2005) 0.80

Mucosal vaccine development for botulinum intoxication. Expert Rev Vaccines (2007) 0.80

A selective T-type Ca2+ channel blocker R(-) efonidipine. Naunyn Schmiedebergs Arch Pharmacol (2008) 0.80

An electrophysiological study of muscarinic and nicotinic receptors of rat paratracheal ganglion neurons and their inhibition by Z-338. Br J Pharmacol (2002) 0.79

Neurotoxin A2NTX blocks fast inhibitory and excitatory transmitter release from presynaptic terminals. J Pharmacol Sci (2011) 0.79

Exocytotic release of alanine from cultured cerebellar neurons. Brain Res (2002) 0.79

Relationship between Clostridium septicum alpha-toxin activity and binding to erythrocyte membranes. J Vet Med Sci (2005) 0.79

GABA(A) receptor-mediated presynaptic inhibition on glutamatergic transmission. Brain Res Bull (2010) 0.79

Differential contribution of the residues in C-terminal half of the heavy chain of botulinum neurotoxin type B to its binding to the ganglioside GT1b and the synaptotagmin 2/GT1b complex. Microb Pathog (2006) 0.79

Effects of tetanus toxin on spontaneous and evoked transmitter release at inhibitory and excitatory synapses in the rat SDCN neurons. Toxicon (2011) 0.79

Multi-locus variable number tandem repeat analysis for Clostridium botulinum type B isolates in Japan: comparison with other isolates and genotyping methods. Infect Genet Evol (2013) 0.79

Purification and sensitivity of Clostridium chauvoei hemolysin to various erythrocytes. Comp Immunol Microbiol Infect Dis (2006) 0.79

Differential effects of divalent cations on spontaneous and evoked glycine release from spinal interneurons. J Neurophysiol (2008) 0.79

In vivo molecular imaging analysis of a nasal vaccine that induces protective immunity against botulism in nonhuman primates. J Immunol (2010) 0.79