|
1
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
|
2
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
|
3
|
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
Nature
|
2011
|
13.25
|
|
4
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
|
5
|
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
|
Nat Genet
|
2012
|
5.48
|
|
6
|
Physical activity from childhood to adulthood: a 21-year tracking study.
|
Am J Prev Med
|
2005
|
5.28
|
|
7
|
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.
|
PLoS Med
|
2011
|
3.94
|
|
8
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
|
9
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
10
|
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
|
Nat Genet
|
2012
|
3.04
|
|
11
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
|
12
|
Seventy-five genetic loci influencing the human red blood cell.
|
Nature
|
2012
|
2.77
|
|
13
|
Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.
|
PLoS Med
|
2013
|
2.73
|
|
14
|
A genome-wide association meta-analysis identifies new childhood obesity loci.
|
Nat Genet
|
2012
|
2.60
|
|
15
|
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.
|
Nat Genet
|
2013
|
2.36
|
|
16
|
Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
|
PLoS Genet
|
2012
|
1.97
|
|
17
|
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.
|
Nat Genet
|
2011
|
1.92
|
|
18
|
Genome-wide association and functional follow-up reveals new loci for kidney function.
|
PLoS Genet
|
2012
|
1.68
|
|
19
|
Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.
|
PLoS Genet
|
2013
|
1.64
|
|
20
|
Genome-wide association analysis identifies susceptibility loci for migraine without aura.
|
Nat Genet
|
2012
|
1.64
|
|
21
|
WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk.
|
PLoS Genet
|
2012
|
1.55
|
|
22
|
Genetic determinants of serum testosterone concentrations in men.
|
PLoS Genet
|
2011
|
1.45
|
|
23
|
Distinct variants at LIN28B influence growth in height from birth to adulthood.
|
Am J Hum Genet
|
2010
|
1.37
|
|
24
|
Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake.
|
Am J Clin Nutr
|
2013
|
1.35
|
|
25
|
Effect of 7-year infancy-onset dietary intervention on serum lipoproteins and lipoprotein subclasses in healthy children in the prospective, randomized Special Turku Coronary Risk Factor Intervention Project for Children (STRIP) study.
|
Circulation
|
2003
|
1.32
|
|
26
|
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.
|
PLoS Genet
|
2012
|
1.23
|
|
27
|
Maintenance of genetic variation in human personality: testing evolutionary models by estimating heritability due to common causal variants and investigating the effect of distant inbreeding.
|
Evolution
|
2012
|
1.21
|
|
28
|
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.
|
Hum Mol Genet
|
2012
|
1.14
|
|
29
|
Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci.
|
Hum Mol Genet
|
2011
|
1.13
|
|
30
|
Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.
|
Arch Gen Psychiatry
|
2012
|
1.08
|
|
31
|
Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
|
Am J Hum Genet
|
2013
|
1.06
|
|
32
|
Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts.
|
Am J Epidemiol
|
2012
|
1.03
|
|
33
|
Low-saturated fat dietary counseling starting in infancy improves insulin sensitivity in 9-year-old healthy children: the Special Turku Coronary Risk Factor Intervention Project for Children (STRIP) study.
|
Diabetes Care
|
2006
|
1.02
|
|
34
|
Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site.
|
Am J Hum Genet
|
2012
|
1.01
|
|
35
|
C-peptide improves adenosine-induced myocardial vasodilation in type 1 diabetes patients.
|
Am J Physiol Endocrinol Metab
|
2003
|
0.99
|
|
36
|
The molecular genetic architecture of self-employment.
|
PLoS One
|
2013
|
0.96
|
|
37
|
The effects of adult-type hypolactasia on body height growth and dietary calcium intake from childhood into young adulthood: a 21-year follow-up study--the Cardiovascular Risk in Young Finns Study.
|
Pediatrics
|
2006
|
0.95
|
|
38
|
Scrutiny of the CHRNA5-CHRNA3-CHRNB4 smoking behavior locus reveals a novel association with alcohol use in a Finnish population based study.
|
Int J Mol Epidemiol Genet
|
2013
|
0.93
|
|
39
|
Cardiac autonomic reactivity and recovery in predicting carotid atherosclerosis: the cardiovascular risk in young Finns study.
|
Health Psychol
|
2007
|
0.92
|
|
40
|
Polymorphism in the IL6 promoter region is associated with the risk factors and markers of subclinical atherosclerosis in men: The Cardiovascular Risk in Young Finns Study.
|
Atherosclerosis
|
2008
|
0.91
|
|
41
|
European lactase persistence genotype shows evidence of association with increase in body mass index.
|
Hum Mol Genet
|
2009
|
0.91
|
|
42
|
Dose-dependent vasodilating effects of insulin on adenosine-stimulated myocardial blood flow.
|
Diabetes
|
2002
|
0.89
|
|
43
|
Genome-wide meta-analysis of common variant differences between men and women.
|
Hum Mol Genet
|
2012
|
0.88
|
|
44
|
The polymorphic androgen receptor gene CAG repeat, pituitary-testicular function and andropausal symptoms in ageing men.
|
Int J Androl
|
2003
|
0.88
|
|
45
|
Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking.
|
Genet Epidemiol
|
2013
|
0.87
|
|
46
|
Obesity affects myocardial vasoreactivity and coronary flow response to insulin.
|
Obes Res
|
2002
|
0.86
|
|
47
|
Novel associations for coronary artery disease derived from genome wide association studies are not associated with increased carotid intima-media thickness, suggesting they do not act via early atherosclerosis or vessel remodeling.
|
Atherosclerosis
|
2011
|
0.86
|
|
48
|
Cholesterol absorption and synthesis in children with type 1 diabetes.
|
Diabetes Care
|
2006
|
0.86
|
|
49
|
Polymorphism in the IL10 promoter region and early markers of atherosclerosis: the Cardiovascular Risk in Young Finns Study.
|
Atherosclerosis
|
2009
|
0.85
|
|
50
|
Genome-wide association study of sleep duration in the Finnish population.
|
J Sleep Res
|
2014
|
0.84
|
|
51
|
Resting heart rate and the association of physical fitness with carotid artery stiffness.
|
Am J Hypertens
|
2013
|
0.83
|
|
52
|
Use of combined oral contraceptives alters metabolic determinants and genetic regulation of C-reactive protein. The Cardiovascular Risk in Young Finns Study.
|
Scand J Clin Lab Invest
|
2009
|
0.82
|
|
53
|
A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure.
|
Hum Genet
|
2015
|
0.82
|
|
54
|
Association of apolipoprotein E promoter polymorphisms with bone structural traits is modified by dietary saturated fat intake - the Cardiovascular Risk in Young Finns study.
|
Bone
|
2011
|
0.82
|
|
55
|
Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT.
|
J Bone Miner Res
|
2014
|
0.82
|
|
56
|
Associations between dimensional personality measures and preclinical atherosclerosis: the cardiovascular risk in Young Finns study.
|
J Psychosom Res
|
2012
|
0.82
|
|
57
|
Common variants in Mendelian kidney disease genes and their association with renal function.
|
J Am Soc Nephrol
|
2013
|
0.82
|
|
58
|
Overnight variability in transcutaneous carbon dioxide predicts vascular impairment in women.
|
Exp Physiol
|
2008
|
0.81
|
|
59
|
A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern.
|
Heart Rhythm
|
2012
|
0.81
|
|
60
|
Mapping neurotransmitter networks with PET: an example on serotonin and opioid systems.
|
Hum Brain Mapp
|
2013
|
0.81
|
|
61
|
Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
|
Nat Genet
|
2016
|
0.81
|
|
62
|
Temperament trait Harm Avoidance associates with μ-opioid receptor availability in frontal cortex: a PET study using [(11)C]carfentanil.
|
Neuroimage
|
2012
|
0.79
|
|
63
|
Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.
|
Hum Genet
|
2014
|
0.79
|
|
64
|
Tracking and determinants of LDL particle size in healthy children from 7 to 11 years of age: the STRIP Study.
|
Eur J Pediatr
|
2008
|
0.78
|
|
65
|
[Reduced sitting time improves health].
|
Duodecim
|
2013
|
0.78
|
|
66
|
Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: the Cardiovascular Risk in Young Finns Study.
|
Clin Sci (Lond)
|
2008
|
0.78
|
|
67
|
Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.
|
Nat Genet
|
2016
|
0.77
|
|
68
|
Is dispositional optimism or dispositional pessimism predictive of ideal cardiovascular health? The Young Finns Study.
|
Psychol Health
|
2015
|
0.75
|
|
69
|
[Prevention of cardiovascular diseases--the most recent recommendations from the United States].
|
Duodecim
|
2014
|
0.75
|
|
70
|
Low Childhood Cholesterol Absorption Predisposes to Gallstone Disease: The Cardiovascular Risk in Young Finns Study.
|
J Pediatr Gastroenterol Nutr
|
2017
|
0.75
|
|
71
|
Cold pressor test safety-the incidence of vasovagal reactions.
|
Am J Cardiol
|
2011
|
0.75
|
|
72
|
Osteoblastic activity of the rabbit temporomandibular joint during distraction osteogenesis assessed by [18F]fluoride positron emission tomography.
|
Eur J Oral Sci
|
2002
|
0.75
|
|
73
|
Blunted coronary vasoreactivity to insulin is an early alteration in hypertension.
|
J Vasc Res
|
2003
|
0.75
|
|
74
|
The association between coronary flow reserve and development of coronary calcifications: a follow-up study for 11 years in healthy young men.
|
Eur Heart J Cardiovasc Imaging
|
2012
|
0.75
|
|
75
|
Parental Physical Activity Associates With Offspring's Physical Activity Until Middle Age - A 30-year Study.
|
J Phys Act Health
|
2017
|
0.75
|
|
76
|
The serum copper/zinc ratio in childhood and educational attainment: a population-based study.
|
J Public Health (Oxf)
|
2016
|
0.75
|
|
77
|
Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
|
Nat Genet
|
2016
|
0.75
|